메뉴 건너뛰기




Volumn 4, Issue 2, 2003, Pages 149-155

Have the oxazolidinones lived up to their billing? Future perspectives for this antibacterial class

Author keywords

AZD 2563; Linezolid; Multidrug resistant Gram positive pathogens; New antibacterial agents; Oxazolidinone; Ranbezolid

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIINFECTIVE AGENT; BACTERIAL RNA; CHLORAMPHENICOL; CLINDAMYCIN; DALFOPRISTIN PLUS QUINUPRISTIN; EPEREZOLID; ERYTHROMYCIN; GENTAMICIN; LINCOMYCIN; LINEZOLID; METICILLIN; MONOAMINE OXIDASE INHIBITOR; N [[3 (4 ACETYLPHENYL) 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [4 (METHYLSULFINYL)PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; OXAZOLIDINONE DERIVATIVE; PENICILLIN G; PHENYLPROPANOLAMINE; POSIZOLID; PROTEIN SYNTHESIS INHIBITOR; PSEUDOEPHEDRINE; RANBEZOLID; RNA 23S; SEROTONIN AGONIST; SEROTONIN UPTAKE INHIBITOR; TOLOXATONE; TYRAMINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN; XA 043;

EID: 0037303362     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (36)

References (54)
  • 2
    • 0038811886 scopus 로고    scopus 로고
    • Oxazolidinone antibacterial agents: A critical review
    • in press; note
    • Hutchinson DK: Oxazolidinone antibacterial agents: A critical review. Curr Topics Med Chem (2003): in press. This recent review contains a detailed discussion of the structure-activity relationships in the oxazolidinone class.
    • (2003) Curr Topics Med Chem
    • Hutchinson, D.K.1
  • 3
    • 0023838224 scopus 로고
    • The mechanism of action of DuP-721, a new antibacterial agent: Effects on macromolecular synthesis
    • Eustice DC, Feldman PA, Slee AM: The mechanism of action of DuP-721, a new antibacterial agent: Effects on macromolecular synthesis. Biochem Biophys Res Commun (1988) 150(3):965-971.
    • (1988) Biochem Biophys Res Commun , vol.150 , Issue.3 , pp. 965-971
    • Eustice, D.C.1    Feldman, P.A.2    Slee, A.M.3
  • 5
    • 0030773903 scopus 로고    scopus 로고
    • The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin
    • Lin AH, Murray RW, Vidmar TJ, Marotti KR: The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother (1997) 41(10):2127-2131.
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.10 , pp. 2127-2131
    • Lin, A.H.1    Murray, R.W.2    Vidmar, T.J.3    Marotti, K.R.4
  • 7
    • 0031729229 scopus 로고    scopus 로고
    • The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria
    • Swaney SM, Aoki H, Ganoza MC, Shinabarger DL: The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria. Antimicrob Agents Chemother (1998) 42(12):3251-3255..
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.12 , pp. 3251-3255
    • Swaney, S.M.1    Aoki, H.2    Ganoza, M.C.3    Shinabarger, D.L.4
  • 10
    • 0032549507 scopus 로고    scopus 로고
    • On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria
    • Burghadt H, Schmitz K-L, Müller M: On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria. FEBS Lett (1998) 425(1):40-44.
    • (1998) FEBS Lett , vol.425 , Issue.1 , pp. 40-44
    • Burghadt, H.1    Schmitz, K.-L.2    Müller, M.3
  • 11
    • 0033584879 scopus 로고    scopus 로고
    • Resistance mutations in 23S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl-transferase center
    • Kloss P, Xiong L, Shinabarger DL, Mankin AS: Resistance mutations in 23S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl-transferase center. J Mol Biol (1999) 294(1):93-101.
    • (1999) J Mol Biol , vol.294 , Issue.1 , pp. 93-101
    • Kloss, P.1    Xiong, L.2    Shinabarger, D.L.3    Mankin, A.S.4
  • 12
    • 0036384314 scopus 로고    scopus 로고
    • The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo
    • Thompson J, O'Connor M, Mills JA, Dahlberg AE: The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo. J Mol Biol (2002) 322(2):273-279.
    • (2002) J Mol Biol , vol.322 , Issue.2 , pp. 273-279
    • Thompson, J.1    O'Connor, M.2    Mills, J.A.3    Dahlberg, A.E.4
  • 13
    • 0002625718 scopus 로고    scopus 로고
    • Oxazolidinone resistance is associated with a mutation in the peptidyl-transferase region of 23S rRNA
    • Abs 104
    • Swaney SM, Shinabarger DL, Schaadt RD, Bock JH, Slightom JL, Zurenko GE: Oxazolidinone resistance is associated with a mutation in the peptidyl-transferase region of 23S rRNA. ICAAC (1998) 38: Abs 104.
    • (1998) ICAAC , vol.38
    • Swaney, S.M.1    Shinabarger, D.L.2    Schaadt, R.D.3    Bock, J.H.4    Slightom, J.L.5    Zurenko, G.E.6
  • 14
    • 0031956779 scopus 로고    scopus 로고
    • Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay
    • Murray RW, Schaadt RD, Zurenko GE, Marotti KR: Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay. Antimicrob Agents Chemother (1998) 42(4):947-950.
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.4 , pp. 947-950
    • Murray, R.W.1    Schaadt, R.D.2    Zurenko, G.E.3    Marotti, K.R.4
  • 16
    • 0033797686 scopus 로고    scopus 로고
    • Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action
    • Xiong L, Kloss P, Douthwaite S, Andersen NM, Swaney S, Shinabarger DL, Mankin AS: Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. J Bacteriol (2000) 182(19):5325-5331.
    • (2000) J Bacteriol , vol.182 , Issue.19 , pp. 5325-5331
    • Xiong, L.1    Kloss, P.2    Douthwaite, S.3    Andersen, N.M.4    Swaney, S.5    Shinabarger, D.L.6    Mankin, A.S.7
  • 18
    • 0002895223 scopus 로고    scopus 로고
    • Development of linezolid-resistant Enterococcus faecium in two compassionate use program patients treated with linezolid
    • Abs 848
    • Zurenko GE, Todd WM, Hafkin B, Meyers B, Kauffman C, Bock J, Slightom J, Shinabarger D: Development of linezolid-resistant Enterococcus faecium in two compassionate use program patients treated with linezolid. ICAAC (1999) 39: Abs 848.
    • (1999) ICAAC , vol.39
    • Zurenko, G.E.1    Todd, W.M.2    Hafkin, B.3    Meyers, B.4    Kauffman, C.5    Bock, J.6    Slightom, J.7    Shinabarger, D.8
  • 19
    • 0036177450 scopus 로고    scopus 로고
    • Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: Report from the SENTRY Antimicrobial Surveillance Program
    • Jones RN, Della-Latta P, Lee LV, Beidenbach DJ: Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: Report from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis (2002) 42(2):137-139.
    • (2002) Diagn Microbiol Infect Dis , vol.42 , Issue.2 , pp. 137-139
    • Jones, R.N.1    Della-Latta, P.2    Lee, L.V.3    Beidenbach, D.J.4
  • 20
    • 0037076032 scopus 로고    scopus 로고
    • Nosocomial spread of linezolid-resistant, vancomycin-resistant Enterococcus faecium
    • note
    • Herrero IA, Issa NC, Patel R: Nosocomial spread of linezolid-resistant, vancomycin-resistant Enterococcus faecium. N Eng J Med (2002) 346(11):867-869. Describes transmission of a linezolid-resistant strain of E faecium, which developed in a patient treated with linezolid, to other patients in the same transplantation unit who had not been treated with linezolid.
    • (2002) N Eng J Med , vol.346 , Issue.11 , pp. 867-869
    • Herrero, I.A.1    Issa, N.C.2    Patel, R.3
  • 21
    • 0036841967 scopus 로고    scopus 로고
    • Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by RT-PCR and PCR restriction fragment length polymorphism analysis
    • Woolford N, Tysall L, Auckland C, Stockdale MW, Lawson AJ, Walker RA, Livermore DM: Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by RT-PCR and PCR restriction fragment length polymorphism analysis. J Clin Microbiol (2002) 40(11):4298-4300.
    • (2002) J Clin Microbiol , vol.40 , Issue.11 , pp. 4298-4300
    • Woolford, N.1    Tysall, L.2    Auckland, C.3    Stockdale, M.W.4    Lawson, A.J.5    Walker, R.A.6    Livermore, D.M.7
  • 23
    • 0036783696 scopus 로고    scopus 로고
    • Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis
    • Marshall SH, Donskey CJ, Hutton-Thomas R, Salata RA, Rice LB: Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis. Antimicrob Agents Chemother (2002) 46(10):3334-3336. Describes the impact of the copy number changes of rDNA on the linezolid minimum inhibitory concentration.
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.10 , pp. 3334-3336
    • Marshall, S.H.1    Donskey, C.J.2    Hutton-Thomas, R.3    Salata, R.A.4    Rice, L.B.5
  • 24
    • 0035991983 scopus 로고    scopus 로고
    • In vitro evaluation of AZD-2563, a novel oxazolidinone, against 603 recent staphylococcal isolates
    • Anderegg TR, Biedenbach DJ, Jones RN: In vitro evaluation of AZD-2563, a novel oxazolidinone, against 603 recent staphylococcal isolates. Antimicrob Agents Chemother (2002) 46(8):2662-2664.
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.8 , pp. 2662-2664
    • Anderegg, T.R.1    Biedenbach, D.J.2    Jones, R.N.3
  • 25
    • 0036668114 scopus 로고    scopus 로고
    • In vitro activity of AZD-2563, a novel oxazolidinone, against European Gram-positive cocci
    • note
    • Fluit AC, Schmitz F-J, Verhoef J, Milatovic D: In vitro activity of AZD-2563, a novel oxazolidinone, against European Gram-positive cocci. J Antimicrob Chemother (2002) 50(2):271-276. Comprehensive comparative study of the antibacterial activity of AZD-2563 and linezolid with 1543 staphylococci, enterococci and streptococci using reference methods of the National Committee for Clinical Laboratory Standards (USA).
    • (2002) J Antimicrob Chemother , vol.50 , Issue.2 , pp. 271-276
    • Fluit, A.C.1    Schmitz, F.-J.2    Verhoef, J.3    Milatovic, D.4
  • 27
    • 0036720617 scopus 로고    scopus 로고
    • Comparative activities of the oxazolidinone AZD-2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae
    • Baum SE, Crawford SA, McElmeel ML, Whitney CG, Jorgensen JH: Comparative activities of the oxazolidinone AZD-2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother (2002) 46(9):3094-3095.
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.9 , pp. 3094-3095
    • Baum, S.E.1    Crawford, S.A.2    McElmeel, M.L.3    Whitney, C.G.4    Jorgensen, J.H.5
  • 28
    • 0035996097 scopus 로고    scopus 로고
    • Anti-pneumococcal activity of AZD-2563, a new oxazolidinone, compared with nine other agents
    • Peric M, Lin G, Clark CL, Jacobs MR, Appelbaum PC: Anti-pneumococcal activity of AZD-2563, a new oxazolidinone, compared with nine other agents. J Antimicrob Chemother (2002) 50(1):95-100.
    • (2002) J Antimicrob Chemother , vol.50 , Issue.1 , pp. 95-100
    • Peric, M.1    Lin, G.2    Clark, C.L.3    Jacobs, M.R.4    Appelbaum, P.C.5
  • 29
    • 0036848203 scopus 로고    scopus 로고
    • In vitro activity of 21 antimicrobials against vancomycin-resistant Staphylococcus aureus (VRSA) and heteroVRSA (hVRSA)
    • note
    • Wootton M, Howe RA, Walsh TR, Bennett PM, MacGowan AP: In vitro activity of 21 antimicrobials against vancomycin-resistant Staphylococcus aureus (VRSA) and heteroVRSA (hVRSA). J Antimicrob Chemother (2002) 50(5):760-761. Reports the activity of linezolid against vancomycin-resistant S aureus.
    • (2002) J Antimicrob Chemother , vol.50 , Issue.5 , pp. 760-761
    • Wootton, M.1    Howe, R.A.2    Walsh, T.R.3    Bennett, P.M.4    MacGowan, A.P.5
  • 31
    • 0035996110 scopus 로고    scopus 로고
    • Anti-anaerobic activity of AZD-2563, a new oxazolidinone, compared with eight other agents
    • Ednie LM, Jacobs MR, Appelbaum PC: Anti-anaerobic activity of AZD-2563, a new oxazolidinone, compared with eight other agents. J Antimicrob Chemother (2002) 50(1):101-105.
    • (2002) J Antimicrob Chemother , vol.50 , Issue.1 , pp. 101-105
    • Ednie, L.M.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 33
    • 0034863518 scopus 로고    scopus 로고
    • Susceptibilities of Mycoplasma hominis, M pneumoniae and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines and quinolones
    • Kenny GE, Cartwright FD: Susceptibilities of Mycoplasma hominis, M pneumoniae and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines and quinolones. Antimicrob Agents Chemother (2001) 45(9):2604-2608.
    • (2001) Antimicrob Agents Chemother , vol.45 , Issue.9 , pp. 2604-2608
    • Kenny, G.E.1    Cartwright, F.D.2
  • 34
    • 0032905529 scopus 로고    scopus 로고
    • Recent developments with oxazolidinone antibiotics
    • Reidl B, Endermann R: Recent developments with oxazolidinone antibiotics. Exp Opin Ther Pat (1999) 9(5):625-633.
    • (1999) Exp Opin Ther Pat , vol.9 , Issue.5 , pp. 625-633
    • Reidl, B.1    Endermann, R.2
  • 35
    • 0345056242 scopus 로고    scopus 로고
    • Linezolid injection, linezolid tablets, linezolid for oral suspension
    • Package insert
    • Zyvox: Linezolid injection, linezolid tablets, linezolid for oral suspension. Pharmacia Corp Package insert (2002).
    • (2002) Pharmacia Corp
    • Zyvox1
  • 36
    • 0037442373 scopus 로고    scopus 로고
    • Quinupristin-dalfopristin and linezolid: Evidence and opinion
    • note
    • Eliopoulos GM: Quinupristin-dalfopristin and linezolid: Evidence and opinion. Clin Infect Dis (2003) 36(4):473-481. Opinion paper sponsored by the Antimicrobial usage and Clinical Trials Committee of Infectious Diseases Society of America.
    • (2003) Clin Infect Dis , vol.36 , Issue.4 , pp. 473-481
    • Eliopoulos, G.M.1
  • 37
    • 0035063748 scopus 로고    scopus 로고
    • Linezolid: A review of its use in the management of serious Gram-positive infections
    • note
    • Perry CM, Jarvis B: Linezolid: A review of its use in the management of serious Gram-positive infections. Drugs (2001) 61(4):525-551. Review of studies leading to the regulatory approval of linezolid.
    • (2001) Drugs , vol.61 , Issue.4 , pp. 525-551
    • Perry, C.M.1    Jarvis, B.2
  • 38
    • 0036604489 scopus 로고    scopus 로고
    • Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections
    • Stevens DL, Herr D, Lampiris H, Hunt JL, Batts DH, Hafkin B: Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis (2002) 34(11):1481-1490.
    • (2002) Clin Infect Dis , vol.34 , Issue.11 , pp. 1481-1490
    • Stevens, D.L.1    Herr, D.2    Lampiris, H.3    Hunt, J.L.4    Batts, D.H.5    Hafkin, B.6
  • 39
    • 0001024214 scopus 로고    scopus 로고
    • Linezolid in the treatment of vancomycin-resistant enterococcus: A dose-comparative, multicenter phase III trial
    • Abs 2235.
    • Hartman CS, Leach TS, Kaja RW, Schaser RJ, Todd WM, Hafkin B: Linezolid in the treatment of vancomycin-resistant enterococcus: A dose-comparative, multicenter phase III trial. ICAAC (2000) 40:Abs 2235.
    • (2000) ICAAC , vol.40
    • Hartman, C.S.1    Leach, T.S.2    Kaja, R.W.3    Schaser, R.J.4    Todd, W.M.5    Hafkin, B.6
  • 40
    • 0033973539 scopus 로고    scopus 로고
    • Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant Gram-positive bacterial infections
    • Chien JW, Kucia ML, Salata RA: Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant Gram-positive bacterial infections. Clin Infect Dis (2000) 30(1):146-151.
    • (2000) Clin Infect Dis , vol.30 , Issue.1 , pp. 146-151
    • Chien, J.W.1    Kucia, M.L.2    Salata, R.A.3
  • 42
    • 0036498896 scopus 로고    scopus 로고
    • Thrombocytopenia associated with linezolid therapy
    • note
    • Attassi K, Hershberger E, Alam R, Zervos MJ: Thrombocytopenia associated with linezolid therapy. Clin Infect Dis (2002) 34(5):695-698. An analysis of patients on linezolid for incidence of thrombocytopenia.
    • (2002) Clin Infect Dis , vol.34 , Issue.5 , pp. 695-698
    • Attassi, K.1    Hershberger, E.2    Alam, R.3    Zervos, M.J.4
  • 43
    • 0036680631 scopus 로고    scopus 로고
    • Thrombocytopenia secondary to linezolid administration: What is the risk?
    • Orrick JJ,. Johns T, Janelle J, Ramphal R: Thrombocytopenia secondary to linezolid administration: What is the risk? Clin Infect Dis (2002) 35(3):348-349.
    • (2002) Clin Infect Dis , vol.35 , Issue.3 , pp. 348-349
    • Orrick, J.J.1    Johns, T.2    Janelle, J.3    Ramphal, R.4
  • 47
    • 85046911353 scopus 로고    scopus 로고
    • Linezolid-induced pancytopenia
    • Halpren M: Linezolid-induced pancytopenia. Clin Infect Dis (2002) 35(3):347-348.
    • (2002) Clin Infect Dis , vol.35 , Issue.3 , pp. 347-348
    • Halpren, M.1
  • 48
    • 0036137811 scopus 로고    scopus 로고
    • Linezolid-induced anemia and thrombocytopenia
    • Waldrep TW, Skiest DJ: Linezolid-induced anemia and thrombocytopenia. Pharmacotherapy (2002) 22(1):109-112.
    • (2002) Pharmacotherapy , vol.22 , Issue.1 , pp. 109-112
    • Waldrep, T.W.1    Skiest, D.J.2
  • 49
    • 0035031377 scopus 로고    scopus 로고
    • Linezolid: Pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanolamine HCl, and dextromethorphan HBr
    • Hendershot PE, Antal EJ, Welshman IR, Batts DH, Hopkins NK: Linezolid: Pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanolamine HCl, and dextromethorphan HBr. J Clin Pharmacol (2001) 41(5):563-572.
    • (2001) J Clin Pharmacol , vol.41 , Issue.5 , pp. 563-572
    • Hendershot, P.E.1    Antal, E.J.2    Welshman, I.R.3    Batts, D.H.4    Hopkins, N.K.5
  • 50
    • 0035040180 scopus 로고    scopus 로고
    • Linezolid, a novel oxazolidinone antibiotic: Assessment of monoamine oxidase inhibition using pressor response to oral tyramine
    • Antal EJ, Hendersot PE, Batts DH, Sheu W-P, Hopkins NK, Donaldson KM: Linezolid, a novel oxazolidinone antibiotic: Assessment of monoamine oxidase inhibition using pressor response to oral tyramine. J Clin Pharmacol (2001) 41(5):552-562.
    • (2001) J Clin Pharmacol , vol.41 , Issue.5 , pp. 552-562
    • Antal, E.J.1    Hendersot, P.E.2    Batts, D.H.3    Sheu, W.-P.4    Hopkins, N.K.5    Donaldson, K.M.6
  • 51
    • 0037097653 scopus 로고    scopus 로고
    • Serotonin syndrome and linezolid
    • Wigen CL, Goetz MB: Serotonin syndrome and linezolid. Clin Infect Dis (2002) 34(12):1651-1652.
    • (2002) Clin Infect Dis , vol.34 , Issue.12 , pp. 1651-1652
    • Wigen, C.L.1    Goetz, M.B.2
  • 53
    • 0344194022 scopus 로고    scopus 로고
    • Proposed susceptibility testing criteria for AZD-2563, a novel long-acting oxazolidinone (OXA)
    • Abs 1308.
    • Anderegg T, Biedenbach D, Kirby J, Jones RN: Proposed susceptibility testing criteria for AZD-2563, a novel long-acting oxazolidinone (OXA). ICAAC (2002) 42:Abs 1308.
    • (2002) ICAAC , vol.42
    • Anderegg, T.1    Biedenbach, D.2    Kirby, J.3    Jones, R.N.4
  • 54
    • 0037111554 scopus 로고    scopus 로고
    • Risk factors associated with the development of infection with linezolid and vancomycin-resistant Enterococcus faecium
    • note
    • Pai MP, Rodvold KA, Schreckenberger PC, Gonzales RD, PetrolattiJM, Quinn JP: Risk factors associated with the development of infection with linezolid and vancomycin-resistant Enterococcus faecium. Clin Infect Dis 35(10):1269-1272. Discussion of the factors associated with the emergence of linezolid-resistant E faecium.
    • (2002) Clin Infect Dis , vol.35 , Issue.10 , pp. 1269-1272
    • Pai, M.P.1    Rodvold, K.A.2    Schreckenberger, P.C.3    Gonzales, R.D.4    Petrolatti, J.M.5    Quinn, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.