Enhanced 11β-hydroxysteroid dehydrogenase type 1 activity in stress adaptation in the guinea pig

Journal of Endocrinology

Volumn 176, Issue 2, 2003, Pages 185-192

  Quinkler, M ^a   Troeger, H ^a   Eigendorff, E ^a   Maser Gluth, C ^b   Stiglic, A ^a   Oelkers, W ^a   Bahr V ^a   Diederich, S ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ANDROSTENEDIONE; CORTICOTROPIN; CORTISONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; HYDROXYPROGESTERONE; MINERALOCORTICOID RECEPTOR; OXIDOREDUCTASE; PROGESTERONE; TETRAHYDROCORTISOL; ANTIINFLAMMATORY AGENT; HYDROXYSTEROID DEHYDROGENASE;

ADAPTATION; ANDROSTENEDIONE BLOOD LEVEL; ANIMAL TISSUE; CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; GUINEA PIG; HORMONE METABOLISM; HORMONE SYNTHESIS; HYDROCORTISONE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; STRESS; URINE LEVEL; ADAPTIVE BEHAVIOR; ANIMAL; ARTICLE; BLOOD; CULTURE TECHNIQUE; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; MENTAL STRESS; METABOLISM; PHYSIOLOGY; STIMULATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; 17-ALPHA-HYDROXYPROGESTERONE; ADAPTATION, PSYCHOLOGICAL; ADRENOCORTICOTROPIC HORMONE; ANDROSTENEDIONE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CORTISONE; CULTURE TECHNIQUES; ENZYME ACTIVATION; GUINEA PIGS; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASES; KIDNEY; LIVER; MALE; PROGESTERONE; STIMULATION, CHEMICAL; STRESS, PSYCHOLOGICAL;

EID: 0037291642     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1760185     Document Type: Review

References (55)

1. Abel SM, Back DJ, Maggs JL & Park BK 1993 Cortisol metabolism in vitro. II Species difference. Journal of Steroid Biochemistry and Molecular Biology 45 445-453.
2. Albiston AL, Obeyesekere VR, Smith RE & Krozowski ZS 1994 Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Molecular and Cellular Endocrinology 105 R11-R17.
3. Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE & Evans RM 1987 Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237 268-275.
4. Bach PH, Vickers AEM, Fisher R, Baumann A, Brittebo E, Carlile DJ, Koster HJ, Lake BG, Salmon F, Sawyer TW & Skibinski G 1996 The use of tissue slices for pharmacotoxicology studies. The report and recommendations of ECVAM workshop 20. Alternatives to Laboratory Animals 24 893-923.
5. Best R, Nelson S & Walker BR 1997 Dexamethasone and 11-dehydrodexamethasone as tools to investigate the isoenzymes of 11β-hydroxysteroid dehydrogenase in vitro and in vivo. Journal of Endocrinology 153 41-48.
6. Brown RW, Chapman KE, Edwards CR & Seckl JR 1993 Human placental 11β-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology 132 2614-2621.
7. Cooper MS, Rabbitt EH, Goddard PE, Bartlett WA, Hewison M & Stewart PM 2002 Osteoblastic 11β-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure. Journal of Bone and Mineral Research 17 979-986.
8. Diederich S, Quinkler M, Miller K, Heilmann P, Schöneshöfer M & Oelkers W 1996 Human kidney 11β-hydroxysteroid dehydrogenase: regulation by adrenocorticotropin? European Journal of Endocrinology 134 301-307.
9. Diederich S, Hanke B, Oelkers W & Bähr V 1997 Metabolism of dexamethasone in the human kidney: nicotinamide adenine dinucleotide-dependent 11-reduction. Journal of Clinical Endocrinology and Metabolism 82 1598-1602.
10. Edwards CR, Stewart PM, Burt D, Brett L, McIntyre MA, Sutanto WS, de Kloet ER & Monder C 1988 Localisation of 11β-hydroxysteroid dehydrogenase - tissue specific protector of the mineralocorticoid receptor. Lancet 2 986-989.
11. Eisenschmid B, Heilmann P, Oelkers W, Rejaibi R & Schöneshöfer M 1987 20-Dihydroisomers of cortisol and cortisone in human urine: excretion rates under different physiological conditions. Journal of Clinical Chemistry and Clinical Biochemistry 25 345-349.
12. Fenske M 1997 Role of cortisol in the ACTH-induced suppression of testicular steroidogenesis in guinea pigs. Journal of Endocrinology 154 407-414.
13. Ferrari P, Sansonnens A, Dick B & Frey FJ 2001 In vivo 11β-HSD-2 activity: variability, salt-sensitivity, and effect of licorice. Hypertension 38 1330-1336.
14. Fujieda K, Goff AK, Pugeat M & Strott CA 1982 Regulation of the pituitary-adrenal axis and corticosteroid-binding globulin-cortisol interaction in the guinea pig. Endocrinology 111 1944-1950.
15. Funder JW, Pearce PT, Smith R & Smith AI 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242 583-585.
16. Hammami MM & Siiteri PK 1991 Regulation of 11β-hydroxysteroid dehydrogenase activity in human skin fibroblasts: enzymatic modulation of glucocorticoid action. Journal of Clinical Endocrinology and Metabolism 73 326-334.
17. Hodgson AJ & Funder JW 1978 Glucocorticoid receptors in the guinea pig. American Journal of Physiology 235 R115-R120.
18. Hundertmark S, Bühler H, Ragosch V, Dinkelborg L, Arabin B & Weitzel HK 1995 Correlation of surfactant phosphatidylcholine synthesis and 11β-hydroxysteroid dehydrogenase in the fetal lung. Endocrinology 136 2573-2578.
19. Jamieson PM, Chapman KE, Edwards CRW & Seckl JR 1995 11β-Hydroxysteroid dehydrogenase is an exclusive 11β-reductase in primary cultures of rat hepatocytes: effect of physiochemical and hormonal manipulations. Endocrinology 136 4754-4761.
20. Jamieson PM, Chapman KE & Seckl JR 1999 Tissue- and temporal-specific regulation of 11β-hydroxysteroid dehydrogenase type 1 by glucocorticoids in vivo. Journal of Steroid Biochemistry and Molecular Biology 68 245-250.
21. Jamieson PM, Walker BR, Chapman KE, Andrews R, Rossiter S & Seckl JR 2000 11β-Hydroxysteroid dehydrogenase type 1 is a predominant 11β-reductase in the intact perfused rat liver. Journal of Endocrinology 165 685-692.
22. Keightley MC & Fuller PJ 1996 Anomalies in the endocrine axes of the guinea pig: relevance to human physiology and disease. Endocrine Reviews 17 30-44.
23. Keightley MC, Funder JW & Fuller PJ 1991 Molecular cloning and sequencing of a guinea-pig pro-opiomelanocortin cDNA. Molecular and Cellular Endocrinology 82 89-98.
24. Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, Best R, Brown R, Edwards CR, Seckl JR & Mullins JJ 1997 11 beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. PNAS 94 14924-14929.
25. Kraft N, Hodgson AJ & Funder JW 1979 Glucocorticoid receptor and effector mechanisms: a comparison of the corticosensitive mouse with the corticoresistant guinea pig. Endocrinology 104 344-349.
26. Li KXZ, Smith RE, Ferrari P, Funder JW & Krozowski ZS 1996 Rat 11β-hydroxysteroid dehydrogenase type 2 enzyme is expressed at low levels in the placenta and is modulated by adrenal steroids in the kidney. Molecular and Cellular Endocrinology 120 67-75.
27. Li KXZ, Obeyesekere VR, Krozowski ZS & Ferrari P 1997 Oxoreductase and dehydrogenase activities of the human and rat 11β-hydroxysteroid dehydrogenase type 2 enzyme. Endocrinology 138 2948-2952.
28. Liu YJ, Nakagawa Y, Nasuda K, Saegusa H & Igarashi Y 1996 Effect of growth hormone, insulin and dexamethasone on 11β-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes. Life Sciences 59 227-234.
29. Martin MJ, McClelland AE & Funder JW 1980 The pituitary-adrenal axis in the guinea pig: studies on ACTH secretion. Clinical and Experimental Pharmacology and Physiology 7 46-47.
30. Maser E, Richter E & Friebertshäuser J 1996 The identification of 11β-hydroxysteroid dehydrogenase as carbonyl reductase of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. European Journal of Biochemistry 238 484-489.
31. Maser-Gluth C, Reincke M, Allolio B & Schulze E 2000 Metabolism of glucocorticoids and mineralocorticoids in patients with adrenal incidentalomas. European Journal of Clinical Investigation 30 (Suppl 3) 83-86.
32. Michael AE & Cooke BA 1994 A working hypothesis for the regulation of steroidogenesis and germ cell development in the gonads by glucocorticoids and 11β-hydroxysteroid dehydrogenase (11β-HSD). Molecular and Cellular Endocrinology 100 55-63.
33. Myles K & Funder JW 1994 Type I (mineralocorticoid) receptors in the guinea pig. American Journal of Physiology 267 E268-E272.
34. Nwe KHH, Hamid A, Morat PB & Khalid BAK 2000 Differential regulation of the oxidative 11β-hydroxysteroid dehydrogenase activity in testis and liver. Steroids 65 40-45.
35. Oelkers W, Buchen S, Diederich S, Krain J, Muhme S & Schöneshöfer M 1994 Impaired renal 11β-oxidation of 9 alpha-fluorocortisol: an explanation for its mineralocorticoid potency. Journal of Clinical Endocrinology and Metabolism 78 928-932.
36. Palermo M, Shackleton CHL, Mantero F & Stewart PM 1996 Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man. Clinical Endocrinology 45 605-611.
37. Provencher PH, Tremblay Y, Caron S & Belanger A 1992 Effect of chronic ACTH treatment on guinea-pig adrenal steroidogenesis - steroid plasma levels, steroid adrenal levels, activity of steroidogenic enzymes and their steady-state messenger RNA levels. Journal of Steroid Biochemistry and Molecular Biology 41 69-78.
38. Pu X & Yang K 2000 Guinea pig 11β-hydroxysteroid dehydrogenase type 1: primary structure and catalytic properties. Steroids 65 148-156.
39. Quinkler M, Kosmale B, Bähr V, Oelkers W & Diederich S 1997 Evidence for isoforms of 11β-hydroxysteroid dehydrogenase in the liver and kidney of the guinea pig. Journal of Endocrinology 153 291-298.
40. Quinkler M, Johanssen S, Grossmann C, Bähr V, Muller M, Oelkers W & Diederich S 1999 Progesterone metabolism in the human kidney and inhibition of 11β-hydroxysteroid dehydrogenase type 2 by progesterone and its metabolites. Journal of Clinical Endocrinology and Metabolism 84 4165-4171.
41. Quinkler M, Oelkers W & Diederich S 2000. In vivo measurement of renal 11β-hydroxysteroid dehydrogenase type 2 activity. Journal of Clinical Endocrinology and Metabolism 85 4921-4922.
42. Quinkler M, Oelkers W & Diederich S 2001 Clinical implications of glucocorticoid metabolism by 11β-hydroxysteroid dehydrogenases in target tissues. European Journal of Endocrinology 144 87-97.
43. Rusvai E & Náray-Fejes-Tóth A 1993 A new isoform of 11β-hydroxysteroid dehydrogenase in aldosterone target cells. Journal of Biological Chemistry 268 10717-10720.
44. Shinzawa K, Kominami S & Takemori S 1985 Studies on cytochrome P-450 (P-450 17 alpha,lyase) from guinea pig adrenal microsomes. Dual function of a single enzyme and effect of cytochrome b5. Biochimica et Biophysica Acta 833 151-160.
45. Stewart PM 1996 11β-Hydroxysteroid dehydrogenase: implications for clinical medicine. Clinical Endocrinology 44 493-499.
46. Stewart PM & Krozowski Z 1999 11β-Hydroxysteroid dehydrogenase. Vitamins and Hormones 57 249-324.
47. Stewart PM & Tomlinson JW 2002 Cortisol, 11β-hydroxysteroid dehydrogenase type 1 and central obesity. Trends in Endocrinology and Metabolism 13 94-96.
48. Stewart PM, Whorwood CB & Mason JI 1995 Type 2 11β-hydroxysteroid dehydrogenase in foetal and adult life. Journal of Steroid Biochemistry and Molecular Biology 55 465-471.
49. Tannin GM, Agarwal AK, Mender C, New MI & White PC 1991 The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. Journal of Biological Chemistry 266 16653-16658.
50. Tetsuka M, Thomas FJ, Thomas MJ, Anderson RA, Mason JI & Hillier SG 1997 Differential expression of messenger ribonucleic acids encoding 11β-hydroxysteroid dehydrogenase types 1 and 2 in human granulosa cells. Journal of Clinical Endocrinology and Metabolism 82 2006-2009.
51. Tomlinson JW, Moore J, Cooper MS, Bujalska I, Shahmanesh M, Burt C, Strain A, Hewison M & Stewart PM 2001 Regulation of expression of 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. Endocrinology 142 1982-1989.
52. Ulick S, Wang JZ, Blumenfeld JD & Pickering TG 1992 Cortisol inactivation overload: a mechanism of mineralocorticoid hypertension in the ectopic adrenocorticotropin syndrome. Journal of Clinical Endocrinology and Metabolism 74 963-967.
53. Voice MW, Seckl JR, Edwards CRW & Chapman KE 1996 11β-Hydroxysteroid dehydrogenase type 1 expression in 2S FAZA hepatoma cells is hormonally regulated: a model system for the study of hepatic glucocorticoid metabolism. Biochemical Journal 317 621-625.
54. Walker BR, Campbell JC, Fraser R, Stewart PM & Edwards CR 1992 Mineralocorticoid excess and inhibition of 11β-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. Clinical Endocrinology 37 483-492.
55. Walker BR, Williams BC & Edwards CRW 1994 Regulation of 11β-hydroxysteroid dehydrogenase activity by the hypothalamic-pituitary-adrenal axis in the rat. Journal of Endocrinology 141 467-472.