-
1
-
-
0023743171
-
Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
-
Funder JW, Pearce FT, Smith R, Smith AI 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585
-
(1988)
Science
, vol.242
, pp. 583-585
-
-
Funder, J.W.1
Pearce, F.T.2
Smith, R.3
Smith, A.I.4
-
2
-
-
0021694134
-
11β-Hydroxysteroid dehydrogenase: Fact or fancy
-
Monder C, Shackelton CHL 1984 11β-Hydroxysteroid dehydrogenase: fact or fancy. Steroids 44:383-417
-
(1984)
Steroids
, vol.44
, pp. 383-417
-
-
Monder, C.1
Shackelton, C.H.L.2
-
3
-
-
0023761690
-
Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor
-
Edwards CR, Stewart PM, Burt D, Brett L, McIntyre MA, Sutano WS, deKloet ER, Monder C 1988 Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 1:986-989
-
(1988)
Lancet
, vol.1
, pp. 986-989
-
-
Edwards, C.R.1
Stewart, P.M.2
Burt, D.3
Brett, L.4
McIntyre, M.A.5
Sutano, W.S.6
DeKloet, E.R.7
Monder, C.8
-
4
-
-
0025222242
-
Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: Toward a redefinition of mineralocorticoid action
-
Funder JW, Pearce PT, Myles K, Roy LP 1990 Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action. FASEB J 4:3234-3238
-
(1990)
FASEB J
, vol.4
, pp. 3234-3238
-
-
Funder, J.W.1
Pearce, P.T.2
Myles, K.3
Roy, L.P.4
-
5
-
-
0024789306
-
Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase
-
Agarwal AK, Monder C, Eckstein B, White PC 1989 Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase. J Biol Chem 264:18939-18943
-
(1989)
J Biol Chem
, vol.264
, pp. 18939-18943
-
-
Agarwal, A.K.1
Monder, C.2
Eckstein, B.3
White, P.C.4
-
7
-
-
0025611952
-
Expression of 11β-hydroxysteroid dehydrogenase using recombinant vaccinia virus
-
Agarwal AK, Tuner-Lona MT, Monder C, White PC 1990 Expression of 11β-hydroxysteroid dehydrogenase using recombinant vaccinia virus. Mol Endocrinol 4:1827-1832
-
(1990)
Mol Endocrinol
, vol.4
, pp. 1827-1832
-
-
Agarwal, A.K.1
Tuner-Lona, M.T.2
Monder, C.3
White, P.C.4
-
8
-
-
0027459238
-
Rat liver 11β-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid encodes oxoreductase activity in a mineralocorticoid-responsive toad bladder cell line
-
Duperrex H, Kenouch S, Gaeggler HP, Seckl JR, Edwards C, Farman N, Rossier BC 1993 Rat liver 11β-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid encodes oxoreductase activity in a mineralocorticoid-responsive toad bladder cell line. Endocrinology 132:612-619
-
(1993)
Endocrinology
, vol.132
, pp. 612-619
-
-
Duperrex, H.1
Kenouch, S.2
Gaeggler, H.P.3
Seckl, J.R.4
Edwards, C.5
Farman, N.6
Rossier, B.C.7
-
9
-
-
0028081325
-
+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney
-
+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney. J Biol Chem 269:25959-25962
-
(1994)
J Biol Chem
, vol.269
, pp. 25959-25962
-
-
Agarwal, A.K.1
Mune, T.2
Monder, C.3
White, P.C.4
-
10
-
-
0027159080
-
Human placental 11β-hydroxysteroid dehydrogenase: Evidence for and partial purification of a distinct NAD-dependent isoform
-
Brown RW, Chapman KE, Edwards C, Seckl JR 1993 Human placental 11β-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology 132:2614-2621
-
(1993)
Endocrinology
, vol.132
, pp. 2614-2621
-
-
Brown, R.W.1
Chapman, K.E.2
Edwards, C.3
Seckl, J.R.4
-
12
-
-
0025887907
-
11β-Hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone
-
Naray-Fejes-Toth A, Watlington CO, Fejes-Toth G 1991 11β-Hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology 129:17-21
-
(1991)
Endocrinology
, vol.129
, pp. 17-21
-
-
Naray-Fejes-Toth, A.1
Watlington, C.O.2
Fejes-Toth, G.3
-
13
-
-
0027162955
-
A new isoform of 11β-hydroxysteroid dehydrogenase in aldosterone target cells
-
Rusvai E, Naray-Fejes-Toth A 1993 A new isoform of 11β-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem 268:10717-10720
-
(1993)
J Biol Chem
, vol.268
, pp. 10717-10720
-
-
Rusvai, E.1
Naray-Fejes-Toth, A.2
-
14
-
-
0029035143
-
Detection of human 11β-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts
-
Whorwood CB, Mason JI, Ricketts ML, Howie AJ, Stewart PM 1995 Detection of human 11β-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts. Mol Cell Endocrinol 110:R7-R12
-
(1995)
Mol Cell Endocrinol
, vol.110
-
-
Whorwood, C.B.1
Mason, J.I.2
Ricketts, M.L.3
Howie, A.J.4
Stewart, P.M.5
-
15
-
-
0029065303
-
Glucocorticoid receptor, mineralocorticoid receptors, 11β-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: In situ studies
-
Roland BL, Krozowski ZS, Funder JW 1995 Glucocorticoid receptor, mineralocorticoid receptors, 11β-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: in situ studies. Mol Cell Endocrinol 111:R1-R7
-
(1995)
Mol Cell Endocrinol
, vol.111
-
-
Roland, B.L.1
Krozowski, Z.S.2
Funder, J.W.3
-
16
-
-
0029026673
-
Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta
-
Krozowski Z, Maguire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK 1995 Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol Metab 80:2203-2209
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2203-2209
-
-
Krozowski, Z.1
Maguire, J.A.2
Stein-Oakley, A.N.3
Dowling, J.4
Smith, R.E.5
Andrews, R.K.6
-
17
-
-
0018598286
-
A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol
-
Ulick S, Levine SL, Gunczler P, Zanconato G, Ramirez LC, Rauh W, Rosler A, Bradlow LH, New MI 1979 A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab 49:757-763
-
(1979)
J Clin Endocrinol Metab
, vol.49
, pp. 757-763
-
-
Ulick, S.1
Levine, S.L.2
Gunczler, P.3
Zanconato, G.4
Ramirez, L.C.5
Rauh, W.6
Rosler, A.7
Bradlow, L.H.8
New, M.I.9
-
18
-
-
0026767928
-
Evidence for cortisol as the mineralocorticoid in the syndrome of apparent mineralocorticoid excess
-
Tedde R, Pala A, Melis A, Ulick S 1992 Evidence for cortisol as the mineralocorticoid in the syndrome of apparent mineralocorticoid excess. J Endocrinol Invest 15:471-474
-
(1992)
J Endocrinol Invest
, vol.15
, pp. 471-474
-
-
Tedde, R.1
Pala, A.2
Melis, A.3
Ulick, S.4
-
19
-
-
0029060080
-
A mutation in the USD11B2 gene in a family with apparent mineralocorticoid excess
-
Wilson RC, Krozowski ZS, Li K, Obeyesekere VR, Razzaghyazar M, Harbison MD, Wei JQ, Shackleton C, Funder JW, New MI 1995 A mutation in the USD11B2 gene in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab 80:2263-2266
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2263-2266
-
-
Wilson, R.C.1
Krozowski, Z.S.2
Li, K.3
Obeyesekere, V.R.4
Razzaghyazar, M.5
Harbison, M.D.6
Wei, J.Q.7
Shackleton, C.8
Funder, J.W.9
New, M.I.10
-
20
-
-
0029160972
-
Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase
-
Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC 1995 Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase. Nat Genet 10:394-399
-
(1995)
Nat Genet
, vol.10
, pp. 394-399
-
-
Mune, T.1
Rogerson, F.M.2
Nikkila, H.3
Agarwal, A.K.4
White, P.C.5
-
21
-
-
0028785017
-
Several homozygous mutations in the gene for 11β-hydroxysteroid dehydrogenase type 2 in patients with apparent mineralocorticoid excess
-
Wilson RC, Harbison MD, Krozowski ZS, Funder JW, Shackleton C, Hanauskeabel HM, Wei JQ, Hertecant J, Moran A, Neiberger RE, Balfe JW, Fattah A, Daneman D, Licholai T, New MI 1995 Several homozygous mutations in the gene for 11β-hydroxysteroid dehydrogenase type 2 in patients with apparent mineralocorticoid excess. J Clin Endocrinol Metab 80:3145-3150
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3145-3150
-
-
Wilson, R.C.1
Harbison, M.D.2
Krozowski, Z.S.3
Funder, J.W.4
Shackleton, C.5
Hanauskeabel, H.M.6
Wei, J.Q.7
Hertecant, J.8
Moran, A.9
Neiberger, R.E.10
Balfe, J.W.11
Fattah, A.12
Daneman, D.13
Licholai, T.14
New, M.I.15
-
22
-
-
0030049329
-
Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene
-
Stewart PM, Krozowski ZS, Gupta A, Milford DV, Howie AJ, Sheppard MC, Whorwood CB 1996 Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene. Lancet 1:88-91
-
(1996)
Lancet
, vol.1
, pp. 88-91
-
-
Stewart, P.M.1
Krozowski, Z.S.2
Gupta, A.3
Milford, D.V.4
Howie, A.J.5
Sheppard, M.C.6
Whorwood, C.B.7
-
23
-
-
0025297450
-
Fetal and placental size and risk of hypertension in adult life
-
Barker DJ, Bull AR, Osmond C, Simmonds SJ 1990 Fetal and placental size and risk of hypertension in adult life. Br Med J 301:259-262
-
(1990)
Br Med J
, vol.301
, pp. 259-262
-
-
Barker, D.J.1
Bull, A.R.2
Osmond, C.3
Simmonds, S.J.4
-
24
-
-
0027530474
-
Dysfunction of placental glucocorticoid barrier: Link between fetal environment and adult hypertension?
-
Edwards C, Benediktsson R, Lindsay RS, Seckl JR 1993 Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? Lancet 341:355-357
-
(1993)
Lancet
, vol.341
, pp. 355-357
-
-
Edwards, C.1
Benediktsson, R.2
Lindsay, R.S.3
Seckl, J.R.4
-
25
-
-
0028986997
-
Type 2 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: Its relationship to birth weight and putative role in fetal adrenal steroidogenesis
-
Stewart PM, Rogerson FM, Mason JI 1995 Type 2 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis. J Clin Endocrinol Metab 80:885-890
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 885-890
-
-
Stewart, P.M.1
Rogerson, F.M.2
Mason, J.I.3
-
26
-
-
0026538832
-
Localization of an 11β-hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney
-
Mercer WR, Krozowski ZS 1992 Localization of an 11β-hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology 130:540-543
-
(1992)
Endocrinology
, vol.130
, pp. 540-543
-
-
Mercer, W.R.1
Krozowski, Z.S.2
-
27
-
-
0029999371
-
Substrate and inhibitor specificity of the cloned human 11β-hydroxysteroid dehydrogenase type 2 isoform
-
Ferrari P, Smith RE, Funder JW, Krozowski ZS 1996 Substrate and inhibitor specificity of the cloned human 11β-hydroxysteroid dehydrogenase type 2 isoform. Am J Physiol 270:E900-E904
-
(1996)
Am J Physiol
, vol.270
-
-
Ferrari, P.1
Smith, R.E.2
Funder, J.W.3
Krozowski, Z.S.4
-
28
-
-
84995839597
-
Impaired renal 11β-oxidation of 9α-fluorocortisol: An explanation for its mineralocorticoid potency
-
Oelkers W, Buchen S, Diederich S, Krain J, Muhme S, Schoneshofer M 1994 Impaired renal 11β-oxidation of 9α-fluorocortisol: an explanation for its mineralocorticoid potency. J Clin Endocrinol Metab 78:928-932
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 928-932
-
-
Oelkers, W.1
Buchen, S.2
Diederich, S.3
Krain, J.4
Muhme, S.5
Schoneshofer, M.6
-
29
-
-
0030474851
-
The metabolism of 9α-fluorinated steroids in the human kidney
-
Diederich S, Hanke B, Bähr V, Oelkers W 1996 The metabolism of 9α-fluorinated steroids in the human kidney. Endocr Res 22:803-810
-
(1996)
Endocr Res
, vol.22
, pp. 803-810
-
-
Diederich, S.1
Hanke, B.2
Bähr, V.3
Oelkers, W.4
-
30
-
-
0025979313
-
Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells
-
Heffernan M, Dennis J W 1991 Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells. Nucleic Acid Res 19:85-92
-
(1991)
Nucleic Acid Res
, vol.19
, pp. 85-92
-
-
Heffernan, M.1
Dennis, J.W.2
-
31
-
-
0028856350
-
The R337C mutation generates a high Km 11β-hydroxysteroid dehydrogenase type II enzyme in a family with apparent mineralocorticoid excess
-
Obeyesekere V, Ferrari P, Andrews RK, Wilson RC, New MI, Funder JW, Krozowski ZS 1995 The R337C mutation generates a high Km 11β-hydroxysteroid dehydrogenase type II enzyme in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab 80:3381-3383
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3381-3383
-
-
Obeyesekere, V.1
Ferrari, P.2
Andrews, R.K.3
Wilson, R.C.4
New, M.I.5
Funder, J.W.6
Krozowski, Z.S.7
-
32
-
-
0029954797
-
Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess
-
Ferrari P, Obeyesekere VR, Li K, Wilson RC, New MI, Funder JW, Krozowski ZS 1996 Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess. Mol Cell Endocrinol 119:21-24
-
(1996)
Mol Cell Endocrinol
, vol.119
, pp. 21-24
-
-
Ferrari, P.1
Obeyesekere, V.R.2
Li, K.3
Wilson, R.C.4
New, M.I.5
Funder, J.W.6
Krozowski, Z.S.7
-
33
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding
-
Bradford M 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding. Anal Biochem 72:248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.1
-
34
-
-
0031039926
-
Immunohistochemical and molecular characterization of the rat 11β-hydroxysteroid dehydrogenase type II enzyme
-
Smith RE, Li KXZ, Andrews RK, Krozowski ZS 1997 Immunohistochemical and molecular characterization of the rat 11β-hydroxysteroid dehydrogenase type II enzyme. Endocrinology 138:540-547
-
(1997)
Endocrinology
, vol.138
, pp. 540-547
-
-
Smith, R.E.1
Li, K.X.Z.2
Andrews, R.K.3
Krozowski, Z.S.4
-
35
-
-
0025325667
-
Corticosteroid 11β-dehydrogenase of rat tissues: Immunological studies
-
Monder C, Lakshmi V 1990 Corticosteroid 11β-dehydrogenase of rat tissues: immunological studies. Endocrinology 126:2435-2443
-
(1990)
Endocrinology
, vol.126
, pp. 2435-2443
-
-
Monder, C.1
Lakshmi, V.2
-
36
-
-
0030031914
-
Cloning and production of antisera to human placental 11β-hydroxysteroid dehydrogenase type 2
-
Brown RW, Chapman KE, Kotelevtsev Y, Yau JLW, Lindsay RS, Brett L, Leckie C, Murad P, Lyons V, Mullins JL, Edwards CRW, Seckl JR 1996 Cloning and production of antisera to human placental 11β-hydroxysteroid dehydrogenase type 2. Biochem J 313:1007-1017
-
(1996)
Biochem J
, vol.313
, pp. 1007-1017
-
-
Brown, R.W.1
Chapman, K.E.2
Kotelevtsev, Y.3
Yau, J.L.W.4
Lindsay, R.S.5
Brett, L.6
Leckie, C.7
Murad, P.8
Lyons, V.9
Mullins, J.L.10
Edwards, C.R.W.11
Seckl, J.R.12
-
37
-
-
33646755820
-
NADPH is the major electron donor in reductive biosynthesis
-
Stryer L (ed) Freeman, New York
-
Stryer L 1988 NADPH is the major electron donor in reductive biosynthesis. In: Stryer L (ed) Biochemistry, ed 3. Freeman, New York, pp 321-322
-
(1988)
Biochemistry, Ed 3
, pp. 321-322
-
-
Stryer, L.1
-
38
-
-
0027165109
-
Structure and function of the hepatic form of 11β-hydroxysteroid dehydrogenase in the squirrel monkey an animal model of glucocorticoid resistance
-
Moore CCD, Mellon SH, Murai J, Siiteri PK, Miller WL 1993 Structure and function of the hepatic form of 11β-hydroxysteroid dehydrogenase in the squirrel monkey an animal model of glucocorticoid resistance. Endocrinology 133:368-375
-
(1993)
Endocrinology
, vol.133
, pp. 368-375
-
-
Moore, C.C.D.1
Mellon, S.H.2
Murai, J.3
Siiteri, P.K.4
Miller, W.L.5
-
39
-
-
0026077176
-
Kinetic studies on rat liver 11β-hydroxysteroid dehydrogenase
-
Monder C, Lakshmi V, Miroff Y 1991 Kinetic studies on rat liver 11β-hydroxysteroid dehydrogenase. Biochim Biophys Acta 1115:23-29
-
(1991)
Biochim Biophys Acta
, vol.1115
, pp. 23-29
-
-
Monder, C.1
Lakshmi, V.2
Miroff, Y.3
-
40
-
-
0024410541
-
Licorice inhibits corticosteroid 11β-dehydrogenase of rat kidney and liver: In vivo and in vitro studies
-
Monder C, Stewart PM, Lakshmi V, Valentino R, Burt D, Edwards CR 1989 Licorice inhibits corticosteroid 11β-dehydrogenase of rat kidney and liver: in vivo and in vitro studies. Endocrinology 125:1046-1053
-
(1989)
Endocrinology
, vol.125
, pp. 1046-1053
-
-
Monder, C.1
Stewart, P.M.2
Lakshmi, V.3
Valentino, R.4
Burt, D.5
Edwards, C.R.6
|