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Volumn 120, Issue 1, 1996, Pages 67-75

Rat 11β-hydroxysteroid dehydrogenase type 2 enzyme is expressed at low levels in the placenta and is modulated by adrenal steroids in the kidney

Author keywords

11 hydroxysteroid dehydrogenase; Gene expression; Kidney

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTEROID; DEOXYCORTICOSTERONE; DEXAMETHASONE; FLUDROCORTISONE; GLUCOCORTICOID; KIDNEY ENZYME; MINERALOCORTICOID RECEPTOR;

EID: 0029973501     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/0303-7207(96)03822-1     Document Type: Article
Times cited : (45)

References (46)
  • 1
    • 2542624590 scopus 로고
    • Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity
    • Krozowski, Z.S. and Funder, J.W. (1983) Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity. Proc. Natl. Acad. Sci. USA 80, 6056-6060.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6056-6060
    • Krozowski, Z.S.1    Funder, J.W.2
  • 2
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • Funder, J.W., Pearce, P.T., Smith, R. and Smith, A.I. (1988) Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242, 583-585.
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3    Smith, A.I.4
  • 3
    • 0023761690 scopus 로고
    • Localisation of 11 beta-hydroxysteroid dehydrogenase - Tissue specific protector of the mineralocorticoid receptor
    • Edwards, C.R., Stewart, P.M., Burt, D., Brett, L., McIntyre, M.A., Sutanto, W.S., deKloet E.R. and Monder, C. (1988) Localisation of 11 beta-hydroxysteroid dehydrogenase - tissue specific protector of the mineralocorticoid receptor. Lancet 2, 986-989.
    • (1988) Lancet , vol.2 , pp. 986-989
    • Edwards, C.R.1    Stewart, P.M.2    Burt, D.3    Brett, L.4    McIntyre, M.A.5    Sutanto, W.S.6    DeKloet, E.R.7    Monder, C.8
  • 5
    • 0026767928 scopus 로고
    • Evidence for cortisol as the mineralocorticoid in the syndrome of apparent mineralocorticoid excess
    • Tedde, R., Pala, A., Melis, A. and Ulick, S. (1992) Evidence for cortisol as the mineralocorticoid in the syndrome of apparent mineralocorticoid excess. J. Endocrinol. Invest. 15, 471-474.
    • (1992) J. Endocrinol. Invest. , vol.15 , pp. 471-474
    • Tedde, R.1    Pala, A.2    Melis, A.3    Ulick, S.4
  • 6
    • 0028034209 scopus 로고
    • Cloning and tissue distribution of the human 11beta-hydroxysteroid dehydrogenase type 2 enzyme
    • Albiston, A.L., Obeyesekere, V.R., Smith, R.E. and Krozowski, Z.S. (1994) Cloning and tissue distribution of the human 11beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol. Cell. Endocrinol. 105, R11-R17.
    • (1994) Mol. Cell. Endocrinol. , vol.105
    • Albiston, A.L.1    Obeyesekere, V.R.2    Smith, R.E.3    Krozowski, Z.S.4
  • 7
    • 0028081325 scopus 로고
    • NAD(+)-dependent isoform of 11beta-hydroxysteroid dehydrogenase - Cloning and characterization of cDNA from sheep kidney
    • Agarwal, A.K., Mune, T., Monder, C. and White, P.C. (1994) NAD(+)-dependent isoform of 11beta-hydroxysteroid dehydrogenase - cloning and characterization of cDNA from sheep kidney. J. Biol. Chem. 269, 25959-25962.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25959-25962
    • Agarwal, A.K.1    Mune, T.2    Monder, C.3    White, P.C.4
  • 8
    • 0029041767 scopus 로고
    • Expression cloning of the aldosterone target cell-specific 11 beta-hydroxysteroid dehydrogenase from rabbit collecting duct cells
    • Naray-Fejes-Toth, A. and Fejes-Toth, G. (1995) Expression cloning of the aldosterone target cell-specific 11 beta-hydroxysteroid dehydrogenase from rabbit collecting duct cells. Endocrinology 136, 2579-2586.
    • (1995) Endocrinology , vol.136 , pp. 2579-2586
    • Naray-Fejes-Toth, A.1    Fejes-Toth, G.2
  • 9
    • 0029122448 scopus 로고
    • Cloning, expression, and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11 beta-hydroxysteroid dehydrogenase
    • Zhou, M.Y., Gomez-Sanchez, E.P., Cox, D.L., Cosby, D. and Gomez-Sanchez, C.E. (1995) Cloning, expression, and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11 beta-hydroxysteroid dehydrogenase. Endocrinology 136, 3729-3734.
    • (1995) Endocrinology , vol.136 , pp. 3729-3734
    • Zhou, M.Y.1    Gomez-Sanchez, E.P.2    Cox, D.L.3    Cosby, D.4    Gomez-Sanchez, C.E.5
  • 10
    • 0029035143 scopus 로고
    • Detection of human 11 beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts
    • Whorwood, C.B., Mason, J.I., Ricketts, M.L., Howie, A.J. and Stewart, P.M. (1995) Detection of human 11 beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts. Mol. Cell. Endocrinol. 110, R7-R12.
    • (1995) Mol. Cell. Endocrinol. , vol.110
    • Whorwood, C.B.1    Mason, J.I.2    Ricketts, M.L.3    Howie, A.J.4    Stewart, P.M.5
  • 11
    • 0029065303 scopus 로고
    • Glucocorticoid receptor, mineralocorticoid receptors, 11 beta-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: In situ studies
    • Roland, B.L., Krozowski, Z.S. and Funder, J.W. (1995) Glucocorticoid receptor, mineralocorticoid receptors, 11 beta-hydroxysteroid dehydrogenase-1 and -2 expression in rat brain and kidney: in situ studies. Mol. Cell. Endocrinol. 111, R1-R7.
    • (1995) Mol. Cell. Endocrinol. , vol.111
    • Roland, B.L.1    Krozowski, Z.S.2    Funder, J.W.3
  • 12
    • 0029026673 scopus 로고
    • Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta
    • Krozowski, Z., Maguire, J.A., Stein-Oakley, A.N., Dowling, J., Smith, R.E. and Andrews, R.K. (1995) Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J. Clin. Endocrinol. Metab. 80, 2203-2209.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 2203-2209
    • Krozowski, Z.1    Maguire, J.A.2    Stein-Oakley, A.N.3    Dowling, J.4    Smith, R.E.5    Andrews, R.K.6
  • 13
    • 0027530474 scopus 로고
    • Dysfunction of placental glucocorticoid barrier - Link between fetal environment and adult hypertension
    • Edwards, C., Benediktsson, R., Lindsay, R.S. and Seckl, J.R. (1993) Dysfunction of placental glucocorticoid barrier - link between fetal environment and adult hypertension. Lancet 341, 355-357.
    • (1993) Lancet , vol.341 , pp. 355-357
    • Edwards, C.1    Benediktsson, R.2    Lindsay, R.S.3    Seckl, J.R.4
  • 15
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
    • Mune, T., Rogerson, F.M., Nikkila, H., Agarwal, A.K. and White, P.C. (1995) Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat. Genet. 10, 394-399.
    • (1995) Nat. Genet. , vol.10 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkila, H.3    Agarwal, A.K.4    White, P.C.5
  • 17
    • 0030049329 scopus 로고    scopus 로고
    • Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene
    • Stewart, P.M., Krozowski, Z.S., Gupta, A., Milford, D.V., Howie, AJ., Sheppard, M.C. and Whorwood, C.B. (1996) Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene. Lancet 347, 88-91.
    • (1996) Lancet , vol.347 , pp. 88-91
    • Stewart, P.M.1    Krozowski, Z.S.2    Gupta, A.3    Milford, D.V.4    Howie, A.J.5    Sheppard, M.C.6    Whorwood, C.B.7
  • 18
    • 0024461815 scopus 로고
    • The intrarenal localization of mineralocorticoid receptors and 11-beta dehydrogenase: Immunocytochemical studies
    • Rundle, S., E, Funder, J., W, Lakshmi, V. and Monder, C. (1989) The intrarenal localization of mineralocorticoid receptors and 11-beta dehydrogenase: immunocytochemical studies. Endocrinology 125, 1700-1704.
    • (1989) Endocrinology , vol.125 , pp. 1700-1704
    • Rundle, S.E.1    Funder, J.W.2    Lakshmi, V.3    Monder, C.4
  • 19
    • 0026095840 scopus 로고
    • The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • Tannin, G.M., Agarwal, A.K., Monder, C., New, M.I. and White, P.C. (1991) The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J. Biol. Chem. 266, 16653-16658.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 20
    • 0028990121 scopus 로고
    • Ovine 11 beta-hydroxysteroid dehydrogenase: From gene to function
    • Yang, K. (1995) Ovine 11 beta-hydroxysteroid dehydrogenase: from gene to function. Endocr. Res. 21, 367-377.
    • (1995) Endocr. Res. , vol.21 , pp. 367-377
    • Yang, K.1
  • 21
    • 0027444885 scopus 로고
    • Defects in the HSD11 gene encoding 11-beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency
    • Nikkila, H., Tannin, G.M., New, M.I., Taylor, N.F., Kalaitzoglou, G., Monder, C. and White, P.C. (1993) Defects in the HSD11 gene encoding 11-beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency. J. Clin. Endocrinol. Metab. 77, 687-691.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 687-691
    • Nikkila, H.1    Tannin, G.M.2    New, M.I.3    Taylor, N.F.4    Kalaitzoglou, G.5    Monder, C.6    White, P.C.7
  • 22
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J.M., Pryzbyla, A.E., MacDonald, R.J. and Rutter, W.J. (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Pryzbyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 23
    • 0026806849 scopus 로고
    • Tissue-specific expression of an 11 beta-hydroxysteroid dehydrogenase with a truncated N-terminal domain. A potential mechanism for differential intracellular localization within mineralocorticoid target cells
    • Krozowski, Z., Obeyesekere, V., Smith, R. and Mercer, W. (1992) Tissue-specific expression of an 11 beta-hydroxysteroid dehydrogenase with a truncated N-terminal domain. A potential mechanism for differential intracellular localization within mineralocorticoid target cells. J. Biol. Chem. 267, 2569-2574.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2569-2574
    • Krozowski, Z.1    Obeyesekere, V.2    Smith, R.3    Mercer, W.4
  • 24
    • 0020045217 scopus 로고
    • Glucocorticoid and mineralocorticoid effects on adrenocorticotropin and beta-endorphin in the adrenalectomized rat
    • Lim, A.T., Khalid, B.A., Clements, J. and Funder, J.W. (1982) Glucocorticoid and mineralocorticoid effects on adrenocorticotropin and beta-endorphin in the adrenalectomized rat. J. Clin. Invest. 69, 1191-1198.
    • (1982) J. Clin. Invest. , vol.69 , pp. 1191-1198
    • Lim, A.T.1    Khalid, B.A.2    Clements, J.3    Funder, J.W.4
  • 25
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding
    • Bradford, M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.1
  • 26
    • 0028982718 scopus 로고
    • Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: Tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney
    • Cole, T.J. (1995) Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney. Endocrinology 136, 4693-4696.
    • (1995) Endocrinology , vol.136 , pp. 4693-4696
    • Cole, T.J.1
  • 27
    • 0029095113 scopus 로고
    • Gene structure and chromosomal localization of the human HSD11k gene encoding the kidney (type 2) isozyme of 11 beta-hydroxysteroid dehydrogenase
    • Agarwal, A.K., Rogerson, F.M., Mune, T. and White, P.C. (1995) Gene structure and chromosomal localization of the human HSD11k gene encoding the kidney (type 2) isozyme of 11 beta-hydroxysteroid dehydrogenase. Genomics 29, 195-199.
    • (1995) Genomics , vol.29 , pp. 195-199
    • Agarwal, A.K.1    Rogerson, F.M.2    Mune, T.3    White, P.C.4
  • 28
    • 0028178473 scopus 로고
    • Regulation of 11 beta-hydroxysteroid dehydrogenase activity by the hypothalamic-pituitary-adrenal axis in the rat
    • Walker, B.R., Williams, B.C. and Edwards, C. (1994) Regulation of 11 beta-hydroxysteroid dehydrogenase activity by the hypothalamic-pituitary-adrenal axis in the rat. J. Endocrinol. 141, 467-472.
    • (1994) J. Endocrinol. , vol.141 , pp. 467-472
    • Walker, B.R.1    Williams, B.C.2    Edwards, C.3
  • 29
    • 0026828603 scopus 로고
    • 11-Beta-hydroxysteroid dehydrogenase and the short-chain alcohol dehydrogenase (SCAD) superfamily
    • Krozowski, Z. (1992) 11-beta-Hydroxysteroid dehydrogenase and the short-chain alcohol dehydrogenase (SCAD) superfamily. Mol. Cell. Endocrinol. 84, C25-C31.
    • (1992) Mol. Cell. Endocrinol. , vol.84
    • Krozowski, Z.1
  • 30
    • 0026538832 scopus 로고
    • Localization of an 11 beta-hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney
    • Mercer, W.R. and Krozowski, Z.S. (1992) Localization of an 11 beta-hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology 130, 540-543.
    • (1992) Endocrinology , vol.130 , pp. 540-543
    • Mercer, W.R.1    Krozowski, Z.S.2
  • 31
    • 0028979946 scopus 로고
    • Cellular localization of 11 beta-hydroxysteroid dehydrogenase 2 gene expression in the ovine adrenal gland
    • Yang, K. and Matthews, S.G. (1995) Cellular localization of 11 beta-hydroxysteroid dehydrogenase 2 gene expression in the ovine adrenal gland. Mol. Cell. Endocrinol. 111, R19-R23.
    • (1995) Mol. Cell. Endocrinol. , vol.111
    • Yang, K.1    Matthews, S.G.2
  • 32
    • 85047676188 scopus 로고    scopus 로고
    • Localization of 11-beta-hydroxysteroid dehydrogenase type 2 in rat tissues: In situ studies
    • Roland, B.L and Funder, J.W. (1996) Localization of 11-beta-Hydroxysteroid dehydrogenase type 2 in rat tissues: in situ studies. Endocrinology 137, 1123-1128.
    • (1996) Endocrinology , vol.137 , pp. 1123-1128
    • Roland, B.L.1    Funder, J.W.2
  • 33
    • 0028969499 scopus 로고
    • Sex- and tissue-specific regulation of 11 beta-hydroxysteroid dehydrogenase mRNA
    • Albiston, A.L., Smith, R.E. and Krozowski, Z.S. (1995) Sex-and tissue-specific regulation of 11 beta-hydroxysteroid dehydrogenase mRNA. Mol. Cell. Endocrinol. 109, 183-188.
    • (1995) Mol. Cell. Endocrinol. , vol.109 , pp. 183-188
    • Albiston, A.L.1    Smith, R.E.2    Krozowski, Z.S.3
  • 34
    • 0025078520 scopus 로고
    • Inhibition of 11 beta-hydroxysteroid dehydrogenase and its effect on epithelial sodium transport
    • Hierholzer, K., Siebe, H. and Fromm, M. (1990) Inhibition of 11 beta-hydroxysteroid dehydrogenase and its effect on epithelial sodium transport. Kidney Int. 38, 673-678.
    • (1990) Kidney Int. , vol.38 , pp. 673-678
    • Hierholzer, K.1    Siebe, H.2    Fromm, M.3
  • 35
    • 0028036675 scopus 로고
    • Epithelial cell localization of type 2 11 beta-hydroxysteroid dehydrogenase in rat and human colon
    • Whorwood, C.B., Ricketts, M.L. and Stewart, P.M. (1994) Epithelial cell localization of type 2 11 beta-hydroxysteroid dehydrogenase in rat and human colon. Endocrinology 135, 2533-2541.
    • (1994) Endocrinology , vol.135 , pp. 2533-2541
    • Whorwood, C.B.1    Ricketts, M.L.2    Stewart, P.M.3
  • 36
    • 0028171669 scopus 로고
    • 11 Beta-hydroxysteroid dehydrogenase in the rat placenta: Developmental changes and the effects of altered glucocorticoid exposure
    • Burton, P.J. and Waddell, B.J. (1994) 11 beta-hydroxysteroid dehydrogenase in the rat placenta: developmental changes and the effects of altered glucocorticoid exposure. J. Endocrinol. 143, 505-513.
    • (1994) J. Endocrinol. , vol.143 , pp. 505-513
    • Burton, P.J.1    Waddell, B.J.2
  • 37
    • 0027972092 scopus 로고
    • Sexual dimorphism of hepatic 11 beta-hydroxysteroid dehydrogenase in the rat: The role of growth hormone patterns
    • Low, S.C., Chapman, K.E., Edwards, C., Wells, T., Robinson, I. and Seckl, J.R. (1994) Sexual dimorphism of hepatic 11 beta-hydroxysteroid dehydrogenase in the rat: the role of growth hormone patterns. J. Endocrinol. 143, 541-548.
    • (1994) J. Endocrinol. , vol.143 , pp. 541-548
    • Low, S.C.1    Chapman, K.E.2    Edwards, C.3    Wells, T.4    Robinson, I.5    Seckl, J.R.6
  • 38
    • 0018172872 scopus 로고
    • The hormonal regulation of hepatic microsomal 11-beta-hydroxysteroid dehydrogenase activity in the rat
    • Lax, E.R., Ghraf, R. and Schriefers, H. (1978) The hormonal regulation of hepatic microsomal 11-beta-hydroxysteroid dehydrogenase activity in the rat. Acta Endocrinol. (Cph.) 89, 352-358.
    • (1978) Acta Endocrinol. (Cph.) , vol.89 , pp. 352-358
    • Lax, E.R.1    Ghraf, R.2    Schriefers, H.3
  • 39
    • 0028286261 scopus 로고
    • Glucocorticoids regulate hippocampal 11 beta-hydroxysteroid dehydrogenase activity and gene expression in vivo in the rat
    • Low, S.C., Moisan, M.P., Noble, J.M., Edwards, C. and Seckl, J.R. (1994) Glucocorticoids regulate hippocampal 11 beta-hydroxysteroid dehydrogenase activity and gene expression in vivo in the rat. J. Neuroendocrinol. 6, 285-290.
    • (1994) J. Neuroendocrinol. , vol.6 , pp. 285-290
    • Low, S.C.1    Moisan, M.P.2    Noble, J.M.3    Edwards, C.4    Seckl, J.R.5
  • 41
    • 0029999371 scopus 로고    scopus 로고
    • Substrate and inhibitior specificity of the cloned human 11 β-hydroxysteroid dehydrogenase type 2 isoform
    • in press
    • Ferrari, P., Smith, R.E., Funder, J.W. and Krozowski, Z.S. (1996) Substrate and inhibitior specificity of the cloned human 11 β-hydroxysteroid dehydrogenase type 2 isoform. Am. J. Physiol. (in press).
    • (1996) Am. J. Physiol.
    • Ferrari, P.1    Smith, R.E.2    Funder, J.W.3    Krozowski, Z.S.4
  • 42
    • 0024567253 scopus 로고
    • Evidence for kinetically distinct forms of corticosteroid 11 beta-dehydrogenase in rat liver microsomes
    • Monder, C. and Lakshmi, V. (1989) Evidence for kinetically distinct forms of corticosteroid 11 beta-dehydrogenase in rat liver microsomes. J. Steroid Biochem. 32, 77-83.
    • (1989) J. Steroid Biochem. , vol.32 , pp. 77-83
    • Monder, C.1    Lakshmi, V.2
  • 43
    • 0027198865 scopus 로고
    • Characterization of 11-beta-hydroxysteroid dehydrogenase of human placenta - Evidence for the existence of two species of 11-beta-hydroxysteroid dehydrogenase
    • Lakshmi, V., Nath, N. and Muneyyircidelale, O. (1993) Characterization of 11-beta-hydroxysteroid dehydrogenase of human placenta - evidence for the existence of two species of 11-beta-hydroxysteroid dehydrogenase. J. Steroid Biochem. Mol. Biol. 45, 391-397.
    • (1993) J. Steroid Biochem. Mol. Biol. , vol.45 , pp. 391-397
    • Lakshmi, V.1    Nath, N.2    Muneyyircidelale, O.3
  • 44
    • 84995839597 scopus 로고
    • Impaired renal 11β-oxidation of 9alpha-fluorocortisol: An explanation for its mineralocorticoid potency
    • Oelkers, W., Buchen, S., Diederich, S., Krain, J., Muhme, S. and Schoneshofer, M. (1994) Impaired renal 11β-oxidation of 9alpha-fluorocortisol: an explanation for its mineralocorticoid potency. J. Clin. Endo. Metab. 78, 928-932.
    • (1994) J. Clin. Endo. Metab. , vol.78 , pp. 928-932
    • Oelkers, W.1    Buchen, S.2    Diederich, S.3    Krain, J.4    Muhme, S.5    Schoneshofer, M.6
  • 45
    • 0025222242 scopus 로고
    • Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: Toward a redefinition of mineralocorticoid action
    • Funder, J.W., Pearce, P.T., Myles, K. and Roy, L.P. (1990) Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action. FASEB J. 4, 3234-3238
    • (1990) FASEB J. , vol.4 , pp. 3234-3238
    • Funder, J.W.1    Pearce, P.T.2    Myles, K.3    Roy, L.P.4
  • 46
    • 0025027755 scopus 로고
    • Glucocorticoid receptors mediate mineralocorticoid-like effects in cultured collecting duct cells
    • Naray-Fejes-Toth, A. and Fejes-Toth, G. (1990) Glucocorticoid receptors mediate mineralocorticoid-like effects in cultured collecting duct cells. Am. J. Physiol. 259, F672-F678.
    • (1990) Am. J. Physiol. , vol.259
    • Naray-Fejes-Toth, A.1    Fejes-Toth, G.2


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