Prothrombotic genetic risk factors in young survivors of myocardial infarction

Blood

Volumn 94, Issue 1, 1999, Pages 46-51

  Ardissino, D ^b   Mannucci, P M ^a   Merlini, P A ^b   Duca, F ^b   Fetiveau, R ^b   Tagliabue, L ^b   Tubaro, M ^b   Galvani, M ^b   Ottani, F ^b   Ferrario, M ^b   Corral, J ^b   Margaglione, M ^b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN IIIA;

ADULT; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENETIC PREDISPOSITION; GENETIC RISK; HEART INFARCTION; HEREDITY; HUMAN; MALE; PRIORITY JOURNAL; THROMBOSIS;

ADULT; ALLELES; ANTIGENS, CD; CASE-CONTROL STUDIES; FACTOR V; FACTOR VII; FEMALE; HUMANS; INTEGRIN BETA3; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MYOCARDIAL INFARCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; POLYMORPHISM, GENETIC; PROTHROMBIN; RISK FACTORS; THROMBOSIS;

EID: 0033169099     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Di Minno G, Grandone E, Margaglione M: Clinical relevance of polymorphic markers of arterial thrombosis. Thromb Haemost 78:462, 1997
2. Grant PJ: Polymorphisms of coagulation fibrinolysis genes: Gene environment interaction and vascular risk. Stroke 28:816, 1997
3. Rozan R: Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR). Thromb Haemost 78:523, 1997
4. Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH: Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64, 1994
5. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM: A common genetic variation in the 3-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698, 1997
6. Zimmerman FH, Cameron A, Fisher LD, Ng G: Myocardial infarction in young adults: Angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Registry). J Am Coll Cardiol 26:654, 1995
7. Kanitz MG, Giovannucci SI, Jones JS, Molt M: Myocardial infarction in young adults: Risk factors and clinical features. J Emerg Med 14:139, 1996
8. Miller SA, Dykes DD, Polesky HF: A simple salting-out procedure for extracting DNA from human nucleate cell. Nucleic Acids Res 16:1219, 1988
9. Margaglione M, Grandone E, Cappucci G, Colaizzo D, Giuliani N, Vecchione G, D'Addedda M, Di Minno G: An alternative method for PAI-I promoter polymorphism (4G/5G) typing. Thromb Haemost 77:605, 1997
10. Weiss EJ, Bray PF, Tayback M, Schulmen SP, Kickler TS, Becker LC, Weiss JL, Gerstenblith G, Goldschmidt-Clermont PJ: A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med 334:1090, 1996
11. 2-terminal globular domain of human platelet glycoprotein Iba has a metionine 145/threonine 145 amino acid polymorphism which is associated with the HPA-2(Ko) alloantigens. J Clin Invest 79:3086, 1992
12. Gonzáles-Conejero R, Lozano ML, Rivera J, Corral J, Aniesta JA, Maroleda JM, Vicente V: Polymorphisms of platelet glycoprotein Ibα associated with arterial thrombotic disease. Blood 92:2771, 1998
13. Green F, Kelleher C, Wilkes HC, Meade TW, Humphries SE: A common genetic polymorphism associated with lower coagulation factor VII levels in healthy individuals. Arterioscler Thromb 11:540, 1991
14. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Metthews RG, Boers GJH, den Heijer H, Kluijtmans LAJ, van den Heuvel LP, Rozen R: A candidate genetic risk factor for vascular disease. A common mutation in the methylenetetrahydrofolate reductase gene. Nat Genet 10:111, 1995
15. Hosmer DW, Lemeshow S: Confidence interval estimation of interaction. Epidemiology 3:452, 1992
16. Fuster V, Badimon L, Badimon JJ, Chesebro JH: Mechanism of disease: The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 326:242, 1992 (part 1)
17. Fuster V, Badimon L, Badimon JJ, Chesebro JH: Mechanism of disease: The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 326:310, 1992 (part 2)
18. Meade TW, Mellows S, Brozovic M, Miller GJ, Chakrabarti RR, North WR, Haines AP, Stirling Y, Imeson JD, Thompson SG: Hemostatic function and ischemic heart disease: Principal results of the Northwick Park Heart Study. Lancet 1:533, 1986
19. Hamsten A, Wiman B, de Faire U, Blomback M: Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 313:1557, 1985
20. Meade TW, Imeson J, Stirling J: Effects of changes in smoking and other characteristics of clotting factors and the risk of ischemic heart disease. Lancet 1:986, 1987
21. Feng D, Lindpaintner K, Larson MG, O'Donnel CJ, Lipinska L, Schimitz C, Sutherland P, Muller JA, Levy D, Toner GH: Increased platelet aggregability associated with platelet GPIIIa PLA2 polymorphism. Circulation 96:I-412, 1997 (suppl)
22. Zotz RB, Deitenbeck R, Rehfeld ISB, Maruhn-Debowski B, Giers G, Bauer H, Winkelmann BR, Scharf RE: Increased platelet sensitivity related to GPIIIa polymorphism (HPA-1b/PLA2). Circulation 96:1-664, 1997 (suppl)
23. Walter DH, Schachinger V, Elsner M, Dimmel S, Zeiher A: Platelet glycoprotein III polymorphisms and the risk of coronary stent thrombosis. Lancet 96:1424, 1997
24. Bray PF, Cannon C, Goldschmidt-Clermont P, Moye LA, Ochiai L, Pfeffer MA, Sacks FM, Braunwald E: The platelet PIA2 and ACE D allele polymorphisms are synergistic for the risk of recurrent events in patients post myocardial infarction and pravastatin reduces the risk. Blood 92:304a, 1998 (suppl 1)
25. A1/A2 polymorphism of platelet glycoprotein IIIa and the risk of myocardial infarction, stroke and venous thrombosis. Lancet 349:385, 1997
26. Gardemann A, Humme J, Stricker J, Nguyen QD, Katz N, Philipp M, Tillmanns H, Hehrlein FW, Rau M, Haberbosch W: Association of the platelet glycoprotein IIIa PIA1/A2 gene polymorphism to coronary artery disease but not to nonfatal myocardial infarction in low risk patients. Thromb Haemost 80:214, 1998
27. Iacoviello L, Di Castelnuovo A, de Kniff P, D'Orazio A, Amore C, Arboretti R, Kluft C, Donati MB: Polymorphism in the coagulation factor VII gene and the risk of myocardial infarction. N Engl J Med 338:79, 1998
28. Selighson U, Zivelin A: Thrombophilia as a multigenic disorder. Thromb Haemost 78:297, 1997
29. Ardissino D, Peyvandi F, Merlini PA, Colombi E, Mannucci PM: Factor V (Arg506 - Gln) mutation in young survivors of myocardial infarction. Thromb Haemost 75:701, 1996
30. Eikelboom JW, Baker RI, Parsons R, Taylor RR, van Bockxmeer FM: No association between the 20210G/A prothrombin gene mutation and premature coronary artery disease. Thromb Haemost 80:878, 1998
31. Rosendaal FR, Siscovick DS, Schwartz SM, Beverly RK, Psaty BM, Longstreth WT Jr, Raghunathan TE, Koepsell TD, Reitsma PH: Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood 89:2817, 1997
32. Rosendaal FR, Siscovick DS, Schwartz SM, Psaty BM, Raghunathan TE, Vos HL: A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood 90:1747, 1997