메뉴 건너뛰기




Volumn 339, Issue 7, 1998, Pages 436-443

Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes

Author keywords

[No Author keywords available]

Indexed keywords

EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; HEPTAPEPTIDE; PLACEBO; UNCLASSIFIED DRUG;

EID: 0008926519     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199808133390704     Document Type: Article
Times cited : (1746)

References (41)
  • 1
    • 0026635686 scopus 로고
    • Thrombosis in unstable angina
    • Chesebro JH, Fuster V. Thrombosis in unstable angina. N Engl J Med 1992;327:192-4.
    • (1992) N Engl J Med , vol.327 , pp. 192-194
    • Chesebro, J.H.1    Fuster, V.2
  • 2
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med 1994;330:956-61.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 3
    • 0030919511 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
    • The IMPACT-II Investigators. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet 1997;349:1422-8.
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 4
    • 0030918995 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study
    • Erratum, Lancet 1997;350:744
    • The CAPTURE Investigators. Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE study. Lancet 1997;349:1429-35. [Erratum, Lancet 1997;350:744.]
    • (1997) Lancet , vol.349 , pp. 1429-1435
  • 5
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
    • The EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 1997;336:1689-96.
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
  • 6
    • 0343376106 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
    • The RESTORE Study Group. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation 1997;96:1445-53.
    • (1997) Circulation , vol.96 , pp. 1445-1453
  • 7
    • 0031606917 scopus 로고    scopus 로고
    • Session highlights from the American Heart Association Scientific Sessions: November 9-12, 1997
    • Alexander IH, Alexander K, Kong DF, Tung CY, Whellan D. Session highlights from the American Heart Association Scientific Sessions: November 9-12, 1997. Am Heart J 1998;135:157-80.
    • (1998) Am Heart J , vol.135 , pp. 157-180
    • Alexander, I.H.1    Alexander, K.2    Kong, D.F.3    Tung, C.Y.4    Whellan, D.5
  • 9
    • 0029062761 scopus 로고
    • Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine
    • Lefkovits J, Plow EF, Topol EJ. Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995;332:1553-9.
    • (1995) N Engl J Med , vol.332 , pp. 1553-1559
    • Lefkovits, J.1    Plow, E.F.2    Topol, E.J.3
  • 10
    • 0028876339 scopus 로고
    • Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy
    • Coller BS. Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy. Circulation 1995;92:2373-80.
    • (1995) Circulation , vol.92 , pp. 2373-2380
    • Coller, B.S.1
  • 11
    • 0030738122 scopus 로고    scopus 로고
    • Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization
    • Lincoff AM, Califf RM, Anderson KM, et al. Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization. J Am Coll Cardiol 1997;30:149-56.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 149-156
    • Lincoff, A.M.1    Califf, R.M.2    Anderson, K.M.3
  • 12
    • 0342777621 scopus 로고    scopus 로고
    • Reduction of recurrent ischemia with abciximab during continuous ECG-ischemia monitoring in patients with unstable angina refractory to standard treatment (CAPTURE)
    • abstract
    • Klootwijk P, Meij S, Melkert R, Simoons ML. Reduction of recurrent ischemia with abciximab during continuous ECG-ischemia monitoring in patients with unstable angina refractory to standard treatment (CAPTURE). J Am Coll Cardiol 1997;29:Suppl A:367A. abstract.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.SUPPL. A
    • Klootwijk, P.1    Meij, S.2    Melkert, R.3    Simoons, M.L.4
  • 13
  • 14
    • 0028930680 scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention
    • Tcheng JE, Harrington RA, Kottke-Marchant K, et al. Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. Circulation 1995;91:2151-7.
    • (1995) Circulation , vol.91 , pp. 2151-2157
    • Tcheng, J.E.1    Harrington, R.A.2    Kottke-Marchant, K.3
  • 15
    • 0028811436 scopus 로고
    • Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention
    • Harrington RA, Kleiman NS, Kottke-Marchant K, et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention. Am J Cardiol 1995;76:1222-7.
    • (1995) Am J Cardiol , vol.76 , pp. 1222-1227
    • Harrington, R.A.1    Kleiman, N.S.2    Kottke-Marchant, K.3
  • 16
    • 0030610564 scopus 로고    scopus 로고
    • Effect of Ca2+ on GP IIb-IIIa interactions with Integrilin: Enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate
    • Phillips DR, Teng W, Arfsten A, et al. Effect of Ca2+ on GP IIb-IIIa interactions with Integrilin: enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate. Circulation 1997;96:1488-94.
    • (1997) Circulation , vol.96 , pp. 1488-1494
    • Phillips, D.R.1    Teng, W.2    Arfsten, A.3
  • 17
    • 10244253888 scopus 로고    scopus 로고
    • Effects of Integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina: A randomized multicenter trial
    • Schulman SP, Goldschmidt-Clermont PJ, Topol EJ, et al. Effects of Integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina: a randomized multicenter trial. Circulation 1996;94:2083-9.
    • (1996) Circulation , vol.94 , pp. 2083-2089
    • Schulman, S.P.1    Goldschmidt-Clermont, P.J.2    Topol, E.J.3
  • 18
    • 0030749074 scopus 로고    scopus 로고
    • Design and methodology of the PURSUIT trial: Evaluating eptifibatide for acute ischemic coronary syndromes
    • Harrington RA. Design and methodology of the PURSUIT trial: evaluating eptifibatide for acute ischemic coronary syndromes. Am J Cardiol 1997;80:Suppl 4A:34B-38B.
    • (1997) Am J Cardiol , vol.80 , Issue.SUPPL. 4A
    • Harrington, R.A.1
  • 21
    • 0027240597 scopus 로고
    • An international randomized trial comparing four thrombolytic strategies tor acute myocardial infarction
    • The GUSTO Investigators. An international randomized trial comparing four thrombolytic strategies tor acute myocardial infarction. N Engl J Med 1993;329:673-82.
    • (1993) N Engl J Med , vol.329 , pp. 673-682
  • 22
    • 0023258694 scopus 로고
    • Thrombolysis in Myocardial Infarction (TIMI) Trial, phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase: clinical findings through hospital discharge
    • Chesebro JH, Knatterud G, Roberts R, et al. Thrombolysis in Myocardial Infarction (TIMI) Trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase: clinical findings through hospital discharge. Circulation 1987;76:142-54.
    • (1987) Circulation , vol.76 , pp. 142-154
    • Chesebro, J.H.1    Knatterud, G.2    Roberts, R.3
  • 23
  • 24
    • 0002296743 scopus 로고
    • Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis
    • Pampallona S, Tsiatis AA. Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis. J Stat Plann Inference 1994;42:19-35.
    • (1994) J Stat Plann Inference , vol.42 , pp. 19-35
    • Pampallona, S.1    Tsiatis, A.A.2
  • 25
    • 0029835392 scopus 로고    scopus 로고
    • A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
    • The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996;335:775-82.
    • (1996) N Engl J Med , vol.335 , pp. 775-782
  • 26
    • 0028349701 scopus 로고
    • Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction: Results of the TIMI IIIB Trial
    • Thrombolysis in Myocardial Ischemia (TIMI) Study Group. Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction: results of the TIMI IIIB Trial. Circulation 1994;89:1545-56.
    • (1994) Circulation , vol.89 , pp. 1545-1556
  • 27
    • 0029101260 scopus 로고
    • A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty
    • Serruys PW, Herrman J-PR, Simon R, et al. A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. N Engl J Med 1995;333:757-63.
    • (1995) N Engl J Med , vol.333 , pp. 757-763
    • Serruys, P.W.1    Herrman, J.-P.R.2    Simon, R.3
  • 28
    • 0029103184 scopus 로고
    • Treatment with bivalirudin (Hirulog) as compared with heparin during coronary angioplasty for unstable or postinfarction angina
    • Bittl JA, Strony J, Brinker JA, et al. Treatment with bivalirudin (Hirulog) as compared with heparin during coronary angioplasty for unstable or postinfarction angina. N Engl J Med 1995;333:764-9.
    • (1995) N Engl J Med , vol.333 , pp. 764-769
    • Bittl, J.A.1    Strony, J.2    Brinker, J.A.3
  • 29
    • 0025737883 scopus 로고
    • Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials
    • Yusuf S, Wittes J, Probsfield J, Tyroler HA. Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. JAMA 1991;266:93-8.
    • (1991) JAMA , vol.266 , pp. 93-98
    • Yusuf, S.1    Wittes, J.2    Probsfield, J.3    Tyroler, H.A.4
  • 30
    • 0029009091 scopus 로고
    • Variations in patient management and outcomes for acute myocardial infarction in the United States and other countries: Results from the GUSTO trial
    • Van de Werf F, Topol EJ, Lee KL, et al. Variations in patient management and outcomes for acute myocardial infarction in the United States and other countries: results from the GUSTO trial. JAMA 1995;273:1586-91.
    • (1995) JAMA , vol.273 , pp. 1586-1591
    • Van De Werf, F.1    Topol, E.J.2    Lee, K.L.3
  • 31
    • 0004224813 scopus 로고    scopus 로고
    • Endpoint adjudication by a Clinical Events Committee can impact the statistical outcome of a clinical trial: Results from GUSTO-IIb
    • abstract
    • Mahaffey KW, Granger CB, Tardiff BE, et al. Endpoint adjudication by a Clinical Events Committee can impact the statistical outcome of a clinical trial: results from GUSTO-IIb. J Am Coll Cardiol 1997;29:Suppl A:410A. abstract.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.SUPPL. A
    • Mahaffey, K.W.1    Granger, C.B.2    Tardiff, B.E.3
  • 32
    • 0030467703 scopus 로고    scopus 로고
    • The myth of the myocardial 'infarctlet' during percutaneous coronary revascularization procedures
    • Abdelmeguid AE, Topol EJ. The myth of the myocardial 'infarctlet' during percutaneous coronary revascularization procedures. Circulation 1996;94:3369-75.
    • (1996) Circulation , vol.94 , pp. 3369-3375
    • Abdelmeguid, A.E.1    Topol, E.J.2
  • 33
    • 0029020065 scopus 로고
    • Characteristics and consequences of myocardial infarction after percutaneous coronary intervention: Insights from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT)
    • Harrington RA, Lincoff AM, Califf RM, et al. Characteristics and consequences of myocardial infarction after percutaneous coronary intervention: insights from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT). J Am Coll Cardiol 1995;25:1693-9.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 1693-1699
    • Harrington, R.A.1    Lincoff, A.M.2    Califf, R.M.3
  • 34
    • 0028940866 scopus 로고
    • One-year follow-up in the Coronary Angioplasty Versus Excisional Atherectomy Trial
    • Elliott JM, Berdan LG, Holmes DR, et al. One-year follow-up in the Coronary Angioplasty Versus Excisional Atherectomy Trial. Circulation 1995;91:2158-66.
    • (1995) Circulation , vol.91 , pp. 2158-2166
    • Elliott, J.M.1    Berdan, L.G.2    Holmes, D.R.3
  • 35
    • 8044222756 scopus 로고    scopus 로고
    • Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization
    • Lincoff AM, Tcheng JE, Califf RM, et al. Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization. Am J Cardiol 1997;79:286-91.
    • (1997) Am J Cardiol , vol.79 , pp. 286-291
    • Lincoff, A.M.1    Tcheng, J.E.2    Califf, R.M.3
  • 36
    • 0027988086 scopus 로고
    • Effects of profound platelet inhibition with c7E3 before coronary angioplasty on complications of coronary bypass surgery: EPIC Investigators
    • Boehrer JD, Kereiakes DJ, Navetta FI, Califf RM, Topol EJ. Effects of profound platelet inhibition with c7E3 before coronary angioplasty on complications of coronary bypass surgery: EPIC Investigators. Am J Cardiol 1994;74:1166-70.
    • (1994) Am J Cardiol , vol.74 , pp. 1166-1170
    • Boehrer, J.D.1    Kereiakes, D.J.2    Navetta, F.I.3    Califf, R.M.4    Topol, E.J.5
  • 37
    • 0028092111 scopus 로고
    • Hirudin in acute myocardial infarction: Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial
    • Antman EM. Hirudin in acute myocardial infarction: safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial. Circulation 1994;90:1624-30.
    • (1994) Circulation , vol.90 , pp. 1624-1630
    • Antman, E.M.1
  • 38
    • 0028037517 scopus 로고
    • Randomized trial of intravenous heparin versus recombinant hirudin tor acute coronary syndromes
    • The GUSTO IIa Investigators. Randomized trial of intravenous heparin versus recombinant hirudin tor acute coronary syndromes. Circulation 1994;90:1631-7.
    • (1994) Circulation , vol.90 , pp. 1631-1637
  • 39
    • 2642654221 scopus 로고    scopus 로고
    • A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
    • The Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Study Investigators. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N Engl J Med 1998;338:1498-505.
    • (1998) N Engl J Med , vol.338 , pp. 1498-1505
  • 40
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction
    • The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. N Engl J Med 1998;338:1488-97.
    • (1998) N Engl J Med , vol.338 , pp. 1488-1497
  • 41
    • 0032560628 scopus 로고    scopus 로고
    • An international, randomized, controlled trial of lamifiban, a platelet glycoprotein IIb/IIIa inhibitor, heparin or both in unstable angina
    • The PARAGON Investigators. An international, randomized, controlled trial of lamifiban, a platelet glycoprotein IIb/IIIa inhibitor, heparin or both in unstable angina. Circulation 1998;97:2386-95.
    • (1998) Circulation , vol.97 , pp. 2386-2395


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.