The Leu33/Pro polymorphism (Pl(A1)/Pl(A2)) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM study

Thrombosis and Haemostasis

Volumn 77, Issue 6, 1997, Pages 1179-1181

  Herrmann, Stefan Martin ^a   Poirier, Odette ^a   Marques Vidal, Pedro ^b   Evans, Alun ^c   Arveiler, Dominique ^d   Luc, Gerald ^e   Emmerich, Joseph ^f   Cambien, François ^a  

^a INSERM   (France)

^b MONICA Project   (France)

^c MONICA Project   (United Kingdom)

^d MONICA Project   (France)

^e MONICA Project   (France)

^f HÔPITAL BROUSSAIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIIA; LEUCINE;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENOTYPE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; BLOOD; GENETIC POLYMORPHISM; GENETICS; MIDDLE AGED; POLYMERASE CHAIN REACTION;

ADULT; HUMANS; LEUCINE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 0031155630     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1656134     Document Type: Article

References (13)

1. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992; 326: 242-50.
2. The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor complex in high-risk coronary angioplasty. N Engl J Med 1994; 330: 956-61.
3. Coller BS. Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy. Circulation 1995; 92: 2373-80.
4. Weiss EJ, Bray PF, Tayback M, Schulman SP. Kickler TS, Becker LC, Weiss JL, Gerstenblith G, Goldschmidt-Clermont PJ. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med 1996; 334: 1090-4.
5. Parra HJ, Arveiler D, Evans AE, Cambou JP, Amouyel P, Bingham A, McMaster D, Schaffer P, Douste-Blazy P, Luc G, Richard JL, Ducimetière P. Cambien F. A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease: the ECTIM Study. Arterioscler Thromb 1992; 12: 701-7.
6. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, Tiret L, Amouyel P, Alhenc-Gelas F, Soubrier F. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-4.
7. WHO MONICA Project principal investigators. The World Health Organization MONICA project (MONItoring trends and determinants in CArdiovascular disease): a major international collaboration. J Clin Epidemiol 1988; 41: 105-14.
8. Jin Y, Dietz HC, Nurden A, Bray PF. Single-strand conformation polymorphism analysis is a rapid and effective method for the identification of mutations and polymorphisms in the gene for glycoprotein IIIa. Blood 1993; 82: 2281-8.
9. Saiki RK. Genetic analysis of enzymatically amplified β-globin and HLA-DQA genomic DNA with allele specific oligonucleotide probes. Nature 1987; 324: 163-6.
10. A polymorphism and myocardial infarction. N Engl J Med 1996; 335: 1071-2.
11. A polymorphism and myocardial infarction. N Engl J Med 1996; 335: 1072-3.
12. Osborn SV, Hampton KK, Smillie D, Channer KS, Daly ME. Platelet glycoprotein IIIa gene polymorphism and myocardial infarction. Lancet 1996; 348: 1309-10.
13. A polymorphism and Japanese diabetic patients with coronary heart disease. Lancet 1996; 348: 1310.