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Volumn 10, Issue 1, 2003, Pages 23-33

C-Med 100®, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo

Author keywords

Cat's claw; Cell number; Expansion; Lymphocyte turnover

Indexed keywords

C MED 100; DRINKING WATER; UNCARIA TOMENTOSA EXTRACT; UNCLASSIFIED DRUG;

EID: 0037282828     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1078/094471103321648629     Document Type: Article
Times cited : (47)

References (40)
  • 1
    • 0026038531 scopus 로고
    • Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa
    • Aquino R, De Feo V, De Simone F, Pizza C, Cirino G (1991) Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa. J Nat Prod 54: 453-459
    • (1991) J Nat Prod , vol.54 , pp. 453-459
    • Aquino, R.1    De Feo, V.2    De Simone, F.3    Pizza, C.4    Cirino, G.5
  • 2
    • 0024446865 scopus 로고
    • Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda
    • Aquino R, De Simone F, Pizza C, Conti C, Stein ML (1989) Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda. J Nat Prod 52: 679-685
    • (1989) J Nat Prod , vol.52 , pp. 679-685
    • Aquino, R.1    De Simone, F.2    Pizza, C.3    Conti, C.4    Stein, M.L.5
  • 3
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Bäuerle PA, Henkel T (1994) Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12: 141-179
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Bäuerle, P.A.1    Henkel, T.2
  • 5
    • 0031465301 scopus 로고    scopus 로고
    • The peripheral T-cell pool: Regulation by non-antigen induced proliferation?
    • Bell EB, Sparshott SM (1997) The peripheral T-cell pool: regulation by non-antigen induced proliferation? Semin Immunol 9: 347-353
    • (1997) Semin Immunol , vol.9 , pp. 347-353
    • Bell, E.B.1    Sparshott, S.M.2
  • 6
    • 0023200330 scopus 로고
    • The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells
    • Bell EB, Sparshott SM, Drayson MT, Ford WL (1987) The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells. J Immunol 139: 1379-1384
    • (1987) J Immunol , vol.139 , pp. 1379-1384
    • Bell, E.B.1    Sparshott, S.M.2    Drayson, M.T.3    Ford, W.L.4
  • 7
    • 0001693512 scopus 로고
    • New quinovic acid glycosides from Uncaria Tomentosa
    • Cerri R, Aquino R, De Simone F, Pizza C (1988) New quinovic acid glycosides from Uncaria Tomentosa. J Nat Prod 51: 257-261
    • (1988) J Nat Prod , vol.51 , pp. 257-261
    • Cerri, R.1    Aquino, R.2    De Simone, F.3    Pizza, C.4
  • 8
    • 0030894638 scopus 로고    scopus 로고
    • Evaluation of the in vitro antioxidant activity in extracts of Uncaria Tomentosa
    • Desmarchelier C, Mongelli E, Coussio J, Ciccia G (1997) Evaluation of the in vitro antioxidant activity in extracts of Uncaria Tomentosa. Phytotherapy Res 11: 254-256
    • (1997) Phytotherapy Res , vol.11 , pp. 254-256
    • Desmarchelier, C.1    Mongelli, E.2    Coussio, J.3    Ciccia, G.4
  • 9
    • 0034305740 scopus 로고    scopus 로고
    • CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
    • Dorfman JR, Stefanova I, Yasutomo K, Germain RN (2000) CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling. Nat Immunol 1: 329-335
    • (2000) Nat Immunol , vol.1 , pp. 329-335
    • Dorfman, J.R.1    Stefanova, I.2    Yasutomo, K.3    Germain, R.N.4
  • 10
    • 0029954114 scopus 로고    scopus 로고
    • Cellular competition modulates survival and selection of CD8+ T cells
    • Freitas AA, Agenes F, Coutinho GC (1996) Cellular competition modulates survival and selection of CD8+ T cells. Eur J Immunol 26: 2640-2649
    • (1996) Eur J Immunol , vol.26 , pp. 2640-2649
    • Freitas, A.A.1    Agenes, F.2    Coutinho, G.C.3
  • 11
    • 0025198395 scopus 로고
    • Selection of VH gene repërtoires: Differentiating B cells of adult bone marrow mimic fetal development
    • Freitas AA, Andrade L, Lembezat MP, Coutinho A (1990) Selection of VH gene repërtoires: differentiating B cells of adult bone marrow mimic fetal development. Int Immunol 2: 15-23
    • (1990) Int Immunol , vol.2 , pp. 15-23
    • Freitas, A.A.1    Andrade, L.2    Lembezat, M.P.3    Coutinho, A.4
  • 12
    • 0034080178 scopus 로고    scopus 로고
    • Population biology of lymphocytes: The flight for survival
    • Freitas AA, Rocha B (2000) Population biology of lymphocytes: the flight for survival. Annu Rev Immunol 18: 83-111
    • (2000) Annu Rev Immunol , vol.18 , pp. 83-111
    • Freitas, A.A.1    Rocha, B.2
  • 13
    • 0027402403 scopus 로고
    • Lymphocyte lifespans: Homeostasis, selection and competition
    • Freitas AA, Rocha BB (1993) Lymphocyte lifespans: homeostasis, selection and competition. Immunol Today 14: 25-29
    • (1993) Immunol Today , vol.14 , pp. 25-29
    • Freitas, A.A.1    Rocha, B.B.2
  • 14
    • 0029049941 scopus 로고
    • The role of cellular competition in B cell survival and selection of B cell repertoires
    • Freitas AA, Rosado MM, Viale AC, Grandien A (1995) The role of cellular competition in B cell survival and selection of B cell repertoires. Eur J Immunol 25: 1729-1738
    • (1995) Eur J Immunol , vol.25 , pp. 1729-1738
    • Freitas, A.A.1    Rosado, M.M.2    Viale, A.C.3    Grandien, A.4
  • 15
    • 0026568356 scopus 로고
    • T cell subset-specific expression of antigen receptor beta chains in alpha chain-transgenic mice
    • Ivars F (1992) T cell subset-specific expression of antigen receptor beta chains in alpha chain-transgenic mice. Eur J Immunol 22: 635-639
    • (1992) Eur J Immunol , vol.22 , pp. 635-639
    • Ivars, F.1
  • 17
    • 0025331311 scopus 로고
    • Analysis of recent thymic emigrants with subset- and maturity-related markers
    • Kelly KA, Scollay R (1990) Analysis of recent thymic emigrants with subset- and maturity-related markers. Int Immunol 2: 419-425
    • (1990) Int Immunol , vol.2 , pp. 419-425
    • Kelly, K.A.1    Scollay, R.2
  • 18
    • 0002655608 scopus 로고
    • Cytostatic, contraceptive and anti-inflammatory agents from Uncaria Tomentosa
    • Keplinger K (1982) Cytostatic, contraceptive and anti-inflammatory agents from Uncaria Tomentosa. In PCT int Appl
    • (1982) PCT Int Appl
    • Keplinger, K.1
  • 19
    • 0030775139 scopus 로고    scopus 로고
    • Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
    • Kirberg J, Berns A, von Boehmer H (1997) Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J Exp Med 186: 1269-1275
    • (1997) J Exp Med , vol.186 , pp. 1269-1275
    • Kirberg, J.1    Berns, A.2    Von Boehmer, H.3
  • 20
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam KP, Kuhn R, Rajewsky K (1997) In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90: 1073-1083
    • (1997) Cell , vol.90 , pp. 1073-1083
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 21
    • 0034886454 scopus 로고    scopus 로고
    • Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble extract of Uncaria tomentosa, C-Med 100
    • Lamm S, Sheng Y, Pero RW (2001) Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble extract of Uncaria tomentosa, C-Med 100. Phytomedicine 8: 267-274
    • (2001) Phytomedicine , vol.8 , pp. 267-274
    • Lamm, S.1    Sheng, Y.2    Pero, R.W.3
  • 25
    • 0024332461 scopus 로고
    • Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo
    • Rocha B, Dautigny N, Pereira P (1989) Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo. Eur J Immunol 19: 905-911
    • (1989) Eur J Immunol , vol.19 , pp. 905-911
    • Rocha, B.1    Dautigny, N.2    Pereira, P.3
  • 26
    • 0030849637 scopus 로고    scopus 로고
    • Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
    • Rooke R, Waltzinger C, Benoist C, Mathis D (1997) Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity 7: 123-134
    • (1997) Immunity , vol.7 , pp. 123-134
    • Rooke, R.1    Waltzinger, C.2    Benoist, C.3    Mathis, D.4
  • 29
    • 0034142139 scopus 로고    scopus 로고
    • Enhanced DNA repair, immune function and reduced toxicity of C-MED 100, a novel aqueous extract from Uncaria tomentosa
    • Sheng Y, Bryngelsson C, Pero RW (2000a) Enhanced DNA repair, immune function and reduced toxicity of C-MED 100, a novel aqueous extract from Uncaria tomentosa. J Ethnopharmacol 69: 115-126
    • (2000) J Ethnopharmacol , vol.69 , pp. 115-126
    • Sheng, Y.1    Bryngelsson, C.2    Pero, R.W.3
  • 30
    • 0031790342 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa
    • Sheng Y, Pero RW, Amiri A, Bryngelsson C (1998) Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anticancer Res 18: 3363-3368
    • (1998) Anticancer Res , vol.18 , pp. 3363-3368
    • Sheng, Y.1    Pero, R.W.2    Amiri, A.3    Bryngelsson, C.4
  • 31
    • 0034108493 scopus 로고    scopus 로고
    • Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa
    • Sheng Y, Pero RW, Wagner H (2000b) Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa. Phytomedicine 7: 137-143
    • (2000) Phytomedicine , vol.7 , pp. 137-143
    • Sheng, Y.1    Pero, R.W.2    Wagner, H.3
  • 32
    • 0032589687 scopus 로고    scopus 로고
    • Class II-independent generation of CD4 memory T cells from effectors
    • Swain SL, Hu H, Huston G (1999) Class II-independent generation of CD4 memory T cells from effectors. Science 286: 1381-1383
    • (1999) Science , vol.286 , pp. 1381-1383
    • Swain, S.L.1    Hu, H.2    Huston, G.3
  • 33
    • 0030249953 scopus 로고    scopus 로고
    • MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span
    • Takeda S, Rodewald HR, Arakawa H, Bluethmann H, Shimizu T (1996) MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity 5: 217-228
    • (1996) Immunity , vol.5 , pp. 217-228
    • Takeda, S.1    Rodewald, H.R.2    Arakawa, H.3    Bluethmann, H.4    Shimizu, T.5
  • 34
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naive or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B (1997a) Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276: 2057-2062
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 35
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naive or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B (1997b) Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276: 2057-2062
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 36
    • 0029147807 scopus 로고
    • The peripheral T cell repertoire: Independent homeostatic regulation of virgin and activated CD8+ T cell pools
    • Tanchot C, Rocha B (1995) The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools. Eur J Immunol 25: 2127-2136
    • (1995) Eur J Immunol , vol.25 , pp. 2127-2136
    • Tanchot, C.1    Rocha, B.2
  • 37
    • 0020346563 scopus 로고
    • Resource competition and community structure
    • Tilman D (1982) Resource competition and community structure. Monogr Popul Biol 17: 1-296
    • (1982) Monogr Popul Biol , vol.17 , pp. 1-296
    • Tilman, D.1
  • 38
    • 0018291288 scopus 로고
    • Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors
    • Unkeless JC (1979) Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J Exp Med 150: 580-596
    • (1979) J Exp Med , vol.150 , pp. 580-596
    • Unkeless, J.C.1
  • 39
    • 0027165835 scopus 로고
    • V region dependent selection of persistent resting peripheral B cells in normal mice
    • Viale AC, Coutinho A, Heyman RA, Freitas AA (1993) V region dependent selection of persistent resting peripheral B cells in normal mice. Int Immunol 5: 599-605
    • (1993) Int Immunol , vol.5 , pp. 599-605
    • Viale, A.C.1    Coutinho, A.2    Heyman, R.A.3    Freitas, A.A.4
  • 40
    • 0022227710 scopus 로고
    • The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action
    • Wagner H, Kreutzkamp B, Jurcic K (1985) [The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action]. Planta Med 419-423
    • (1985) Planta Med , pp. 419-423
    • Wagner, H.1    Kreutzkamp, B.2    Jurcic, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.