Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets

Diabetologia

Volumn 42, Issue 10, 1999, Pages 1219-1227

  MacArthur, D L A ^c   De Koning, E J P ^c   Verbeek, J S ^a   Morris, J F ^c   Clark, A ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b RADCLIFFE INFIRMARY   (United Kingdom)

^c NONE

Author keywords

Amylin; Amyloid; Beta cell secretagogues; Fibrils; Glucose; Islet amyloid polypeptide (IAPP); Islets; Transgenic mice

Indexed keywords

2 OXOISOCAPROIC ACID; AMYLOID; GLUCOSE; GLUTAMINE; LEUCINE; TOLBUTAMIDE;

AMYLOIDOSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNOELECTRON MICROSCOPY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ASSAY; RADIOIMMUNOASSAY; TRANSGENIC MOUSE;

AMYLOID; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SPACE; FEMALE; GLUCOSE; GLUTAMINE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; ISLETS OF LANGERHANS; KETO ACIDS; LEUCINE; MALE; MICE; MICE, TRANSGENIC; TIME FACTORS; TOLBUTAMIDE;

EID: 2142728495     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051295     Document Type: Article

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