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Volumn 41, Issue 1, 2003, Pages 50-63

Loss of microglial ramification in microglia-astrocyte cocultures: Involvement of adenylate cyclase, calcium, phosphatase, and Gi-protein systems

Author keywords

Activation; Calcium; CAMP; In vitro; Microglia; Morphology; Phagocytosis

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CALCIUM IONOPHORE; CYCLIC AMP; CYTOKINE; GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN; KERATAN SULFATASE; METALLOPROTEINASE; PERTUSSIS TOXIN; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROSTAGLANDIN D2; PROTEINASE; THROMBIN;

EID: 0037258020     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10176     Document Type: Article
Times cited : (35)

References (88)
  • 1
    • 0025120244 scopus 로고
    • Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
    • Anderson NG, Maller JL, Tonks NK, Sturgill TW. 1990. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343:651-653.
    • (1990) Nature , vol.343 , pp. 651-653
    • Anderson, N.G.1    Maller, J.L.2    Tonks, N.K.3    Sturgill, T.W.4
  • 2
    • 0027519153 scopus 로고
    • - channel by specific protein kinases and protein phosphatases
    • - channel by specific protein kinases and protein phosphatases. J Biol Chem 268:2037-2047.
    • (1993) J Biol Chem , vol.268 , pp. 2037-2047
    • Berger, H.A.1    Travis, S.M.2    Welsh, M.J.3
  • 3
    • 0020645707 scopus 로고
    • 2+ flux as an initial event in phagocytosis by rat Kupffer cells
    • 2+ flux as an initial event in phagocytosis by rat Kupffer cells. Eur J Biochem 131:539-543.
    • (1983) Eur J Biochem , vol.131 , pp. 539-543
    • Bermelin, M.1    Decker, K.2
  • 4
    • 0033824640 scopus 로고    scopus 로고
    • Phagocytosis of neuronal or glial debris by rnicroglial cells: Upregulation of MHC class II expression and multinuclear giant cell formation in vitro
    • Beyer M, Gimsa U, Eyiipoglu IY, Hailer NP, Nitsch R. 2000. Phagocytosis of neuronal or glial debris by rnicroglial cells: upregulation of MHC class II expression and multinuclear giant cell formation in vitro. Glia 31:262-266.
    • (2000) Glia , vol.31 , pp. 262-266
    • Beyer, M.1    Gimsa, U.2    Eyiipoglu, I.Y.3    Hailer, N.P.4    Nitsch, R.5
  • 5
    • 0021271854 scopus 로고
    • Synthesis of prostanoids and cyclic nucleotides by phagocytosing rat Kupffer cells
    • Birmelin M, Decker K. 1984. Synthesis of prostanoids and cyclic nucleotides by phagocytosing rat Kupffer cells. Eur J Biochem 142:219-225.
    • (1984) Eur J Biochem , vol.142 , pp. 219-225
    • Birmelin, M.1    Decker, K.2
  • 6
    • 0023320961 scopus 로고
    • GTP binding proteins: A key role in cellular communication
    • Bockaert J, Homburger V, Rouot B. 1987. GTP binding proteins: a key role in cellular communication. Biochimie 69:329-338.
    • (1987) Biochimie , vol.69 , pp. 329-338
    • Bockaert, J.1    Homburger, V.2    Rouot, B.3
  • 8
    • 0021111692 scopus 로고
    • Identification of the predominant substrate for ADP-ribosylation by islet activating protein
    • Bokoch GM, Katada T, Northup JK, Hewlett EL, Gilman AG. 1983. Identification of the predominant substrate for ADP-ribosylation by islet activating protein. J Biol Chem 258:2072-2075.
    • (1983) J Biol Chem , vol.258 , pp. 2072-2075
    • Bokoch, G.M.1    Katada, T.2    Northup, J.K.3    Hewlett, E.L.4    Gilman, A.G.5
  • 10
    • 0025833766 scopus 로고
    • Fibronectin and larninin regulate the in vitro differentiation of differentiation of microglial cells
    • Chamak B, Mallat M. 1991. Fibronectin and larninin regulate the in vitro differentiation of differentiation of microglial cells. Neuroscience 45:513-527.
    • (1991) Neuroscience , vol.45 , pp. 513-527
    • Chamak, B.1    Mallat, M.2
  • 11
    • 0029891236 scopus 로고    scopus 로고
    • Regulation of colonystimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1
    • Chen HE, Chang S, Trub T, Neel BG. 1996. Regulation of colonystimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1. Mol Cell Biol 16:3685-3697.
    • (1996) Mol Cell Biol , vol.16 , pp. 3685-3697
    • Chen, H.E.1    Chang, S.2    Trub, T.3    Neel, B.G.4
  • 12
    • 0033662889 scopus 로고    scopus 로고
    • Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury
    • Citron BA, Smirnova IV, Arnold PM, Festoff BW. 2000. Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury. J Neurotrauma 17:1191-1203.
    • (2000) J Neurotrauma , vol.17 , pp. 1191-1203
    • Citron, B.A.1    Smirnova, I.V.2    Arnold, P.M.3    Festoff, B.W.4
  • 13
    • 0033835813 scopus 로고    scopus 로고
    • Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase
    • Defer N, Best-Belpomme M, Hanoune J. 2000. Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am J Physiol Renal Physiol 279:F400-F416.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Defer, N.1    Best-Belpomme, M.2    Hanoune, J.3
  • 14
    • 0003136106 scopus 로고
    • El "tercer elemento" de los centros nerviosos: II, intervencion de la microglia en los procesos patologicos
    • del Rio-Hortega P. 1919. El "tercer elemento" de los centros nerviosos: II, intervencion de la microglia en los procesos patologicos. Bol Soc Esp Biol 9:91-103.
    • (1919) Bol Soc Esp Biol , vol.9 , pp. 91-103
    • Del Rio-Hortega, P.1
  • 15
    • 0017581364 scopus 로고
    • The relation of cyclic AMP levels to phagocytosis and enzyme release in acute inflammation in vivo
    • Deporter DA, Dieppe PA, Glatt M, Willoughby DA. 1977. The relation of cyclic AMP levels to phagocytosis and enzyme release in acute inflammation in vivo. J Pathol 121:129-139.
    • (1977) J Pathol , vol.121 , pp. 129-139
    • Deporter, D.A.1    Dieppe, P.A.2    Glatt, M.3    Willoughby, D.A.4
  • 16
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson DW, Lee SC, Mattiace LA, Yen SH. 1993. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7:75-83.
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4
  • 17
    • 0026041196 scopus 로고
    • Diversity amongst the microglia in growing and regenerating fish CNS: Immunohistochemical characterization using FL.I, an anti-macrophage monoclonal antibody
    • Dowding AJ, Maggs A, Scholes J. 1991. Diversity amongst the microglia in growing and regenerating fish CNS: immunohistochemical characterization using FL.I, an anti-macrophage monoclonal antibody, Glia 4:345-364.
    • (1991) Glia , vol.4 , pp. 345-364
    • Dowding, A.J.1    Maggs, A.2    Scholes, J.3
  • 18
    • 0028829231 scopus 로고
    • IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage
    • Fattori E, Lazzaro D, Musiani P, Modesti A, Alonzi T, Ciliberto G. 1995. IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage. Eur J Neurosci 7:2441-2449.
    • (1995) Eur J Neurosci , vol.7 , pp. 2441-2449
    • Fattori, E.1    Lazzaro, D.2    Musiani, P.3    Modesti, A.4    Alonzi, T.5    Ciliberto, G.6
  • 19
    • 0014721292 scopus 로고
    • Conversion of ATP by mouse lung preparations and by an extract of Bordetella pertussis
    • Fishel CW, O'Bryan BS, Smith DL, Jewell GW. 1970. Conversion of ATP by mouse lung preparations and by an extract of Bordetella pertussis. Int Arch Allergy Appl Immunol 38:457-465.
    • (1970) Int Arch Allergy Appl Immunol , vol.38 , pp. 457-465
    • Fishel, C.W.1    O'Bryan, B.S.2    Smith, D.L.3    Jewell, G.W.4
  • 21
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian D, Baker TJ. 1986. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci 6:2163-2178.
    • (1986) J Neurosci , vol.6 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 22
    • 0028881820 scopus 로고
    • Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte
    • Giulian D, Li J, Bartel S, Broker J, Li X, Kirkpatrick JB. 1995. Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte. J Neurosci 15:7712-7726.
    • (1995) J Neurosci , vol.15 , pp. 7712-7726
    • Giulian, D.1    Li, J.2    Bartel, S.3    Broker, J.4    Li, X.5    Kirkpatrick, J.B.6
  • 23
    • 0027535027 scopus 로고
    • Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils
    • Gomez-Cambronero J, Colasanto JM, Huang CK, Sha'afi RI. 1993. Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils. Biochem J 291: 211-217.
    • (1993) Biochem J , vol.291 , pp. 211-217
    • Gomez-Cambronero, J.1    Colasanto, J.M.2    Huang, C.K.3    Sha'afi, R.I.4
  • 24
    • 0035113010 scopus 로고    scopus 로고
    • A novel role for protein tyrosine phosphatase shpl in controlling glial activation in the normal and injured nervous system
    • Horvat A, Schwaiger F, Hager G, Brocker F, Streif R, Knyazev P, Ullrich A, Kreutzberg GW. 2001. A novel role for protein tyrosine phosphatase shpl in controlling glial activation in the normal and injured nervous system. J Neurosci 21:865-874.
    • (2001) J Neurosci , vol.21 , pp. 865-874
    • Horvat, A.1    Schwaiger, F.2    Hager, G.3    Brocker, F.4    Streif, R.5    Knyazev, P.6    Ullrich, A.7    Kreutzberg, G.W.8
  • 25
    • 0030601207 scopus 로고    scopus 로고
    • A novel gene ibal in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage
    • Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S. 1996. A novel gene ibal in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Comm 224:855-862.
    • (1996) Biochem Biophys Res Comm , vol.224 , pp. 855-862
    • Imai, Y.1    Ibata, I.2    Ito, D.3    Ohsawa, K.4    Kohsaka, S.5
  • 26
    • 0026748742 scopus 로고
    • Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
    • Jalink K, Moolenaar WH. 1992. Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J Cell Biol 118:411-419.
    • (1992) J Cell Biol , vol.118 , pp. 411-419
    • Jalink, K.1    Moolenaar, W.H.2
  • 27
    • 0030755363 scopus 로고    scopus 로고
    • Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: Detection of potential HCP substrates in GM-CSF signal transduction
    • Jiao H, Yang W, Berrada K, Tabrizi M, Shultz L, Yi T. 1997. Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction. Exp Hematol 25:592-600.
    • (1997) Exp Hematol , vol.25 , pp. 592-600
    • Jiao, H.1    Yang, W.2    Berrada, K.3    Tabrizi, M.4    Shultz, L.5    Yi, T.6
  • 28
    • 0032496735 scopus 로고    scopus 로고
    • Transforming growth factor β's 1, 2 and 3 inhibit proliferation of ramified microglia on an astrocyte monolayer
    • Jones LL, Kreutzberg GW, Raivich G. 1998. Transforming growth factor β's 1, 2 and 3 inhibit proliferation of ramified microglia on an astrocyte monolayer. Brain Res 795:301-306.
    • (1998) Brain Res , vol.795 , pp. 301-306
    • Jones, L.L.1    Kreutzberg, G.W.2    Raivich, G.3
  • 30
    • 0023131742 scopus 로고
    • Structure-activity analysis of the activation of pertussis toxin
    • Kaslow HR, Lim LK, Moss J, Lesikar DD. 1987. Structure-activity analysis of the activation of pertussis toxin. Biochemistry 26:123-127.
    • (1987) Biochemistry , vol.26 , pp. 123-127
    • Kaslow, H.R.1    Lim, L.K.2    Moss, J.3    Lesikar, D.D.4
  • 31
    • 0019783304 scopus 로고
    • Islet-activating protein. A modifier of receptor-mediated regulation of rat islet adenylate cyclase
    • Katada T, Ui M. 1981. Islet-activating protein. A modifier of receptormediated regulation of rat islet adenylate cyclase. J Biol Chem 256:8310-8317.
    • (1981) J Biol Chem , vol.256 , pp. 8310-8317
    • Katada, T.1    Ui, M.2
  • 32
    • 0028047334 scopus 로고
    • Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells
    • Kharbanda S, Saleem A, Emoto Y, Stone R, Rapp U, Kufe D. 1994. Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells. J Biol Chem 269:872-878.
    • (1994) J Biol Chem , vol.269 , pp. 872-878
    • Kharbanda, S.1    Saleem, A.2    Emoto, Y.3    Stone, R.4    Rapp, U.5    Kufe, D.6
  • 33
    • 0026581386 scopus 로고
    • Regional and generalized changes in cytosolic free calcium in monocytes during phagocytosis
    • Kim E, Enelow RI, Sullivan GW, Mandell GL. 1992. Regional and generalized changes in cytosolic free calcium in monocytes during phagocytosis. Infect Immun 60:1244-1248.
    • (1992) Infect Immun , vol.60 , pp. 1244-1248
    • Kim, E.1    Enelow, R.I.2    Sullivan, G.W.3    Mandell, G.L.4
  • 34
    • 0030612563 scopus 로고    scopus 로고
    • Proliferation of ramified microglia on an astrocyte monolayer: Characterization of stimulatory and inhibitory cytokines
    • Kloss CUA, Kreutzberg GW, Raivich G. 1997. Proliferation of ramified microglia on an astrocyte monolayer: characterization of stimulatory and inhibitory cytokines. J Neurosci Res 49:248-254.
    • (1997) J Neurosci Res , vol.49 , pp. 248-254
    • Kloss, C.U.A.1    Kreutzberg, G.W.2    Raivich, G.3
  • 35
    • 0033575752 scopus 로고    scopus 로고
    • The integrin family of cell adhesion molecules in the injured brain: Regulation and cellular localization in the normal and regenerating mouse facial nucleus
    • Kloss CUA, Werner A, Shen J, Klein MA, Kreutzberg GW. Raivich G. 1999. The integrin family of cell adhesion molecules in the injured brain: regulation and cellular localization in the normal and regenerating mouse facial nucleus. J Comp Neurol 441:162-178.
    • (1999) J Comp Neurol , vol.441 , pp. 162-178
    • Kloss, C.U.A.1    Werner, A.2    Shen, J.3    Klein, M.A.4    Kreutzberg, G.W.5    Raivich, G.6
  • 36
    • 0035120226 scopus 로고    scopus 로고
    • Effect of lipopolysaccharide on the morphology and integrin immunoreactivity of ramified microglia in the mouse brain and in cell culture
    • Kloss CUA, Bohatschek M, Kreutzberg GW, Raivich G. 2001. Effect of lipopolysaccharide on the morphology and integrin immunoreactivity of ramified microglia in the mouse brain and in cell culture. Exp Neurol 168:32-46.
    • (2001) Exp Neurol , vol.168 , pp. 32-46
    • Kloss, C.U.A.1    Bohatschek, M.2    Kreutzberg, G.W.3    Raivich, G.4
  • 37
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 38
    • 0028268025 scopus 로고
    • Differential role of hematogenous macrophages, resident microglia and astrocytes in antigen presentation and tissue damage during autoin-imune encephalomyelitis
    • Lassmann H, Rinner W, Hickey WF. 1994. Differential role of hematogenous macrophages, resident microglia and astrocytes in antigen presentation and tissue damage during autoin-imune encephalomyelitis, Neuropathol Appl Neurobiol 20:195-196.
    • (1994) Neuropathol Appl Neurobiol , vol.20 , pp. 195-196
    • Lassmann, H.1    Rinner, W.2    Hickey, W.F.3
  • 39
    • 0035284908 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: Contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages
    • Malik ZA, Iyer SS, Kusner DJ. 2001. Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages. J Immunol 166:3392-3401.
    • (2001) J Immunol , vol.166 , pp. 3392-3401
    • Malik, Z.A.1    Iyer, S.S.2    Kusner, D.J.3
  • 40
    • 0029003760 scopus 로고
    • Eicosanoids are produced by microglia, not by astrocytes, in rat glial cell cultures
    • Matsuo M, Hamasaki Y, Fujiyama F, Miyazaki S. 1995. Eicosanoids are produced by microglia, not by astrocytes, in rat glial cell cultures. Brain Res 685:201-204.
    • (1995) Brain Res , vol.685 , pp. 201-204
    • Matsuo, M.1    Hamasaki, Y.2    Fujiyama, F.3    Miyazaki, S.4
  • 42
    • 0035448270 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: A role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity
    • McMahon KA, Wilson NJ, Marks DC, Beecroft TL, Whitty GA, Hamilton JA, Csar XF. 2001. Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity. Biochem J 358(Pt 2):431-436.
    • (2001) Biochem J , vol.358 , Issue.PART 2 , pp. 431-436
    • McMahon, K.A.1    Wilson, N.J.2    Marks, D.C.3    Beecroft, T.L.4    Whitty, G.A.5    Hamilton, J.A.6    Csar, X.F.7
  • 43
    • 0001289054 scopus 로고    scopus 로고
    • FK506 mediates neuroprotection by downregulation of JNK activity and inhibition of microglia activation
    • Mielke K, Brecht S, Lucius R, Herdegen T. 1999. FK506 mediates neuroprotection by downregulation of JNK activity and inhibition of microglia activation. Soc Neurosci Abs 25:289.
    • (1999) Soc Neurosci Abs , vol.25 , pp. 289
    • Mielke, K.1    Brecht, S.2    Lucius, R.3    Herdegen, T.4
  • 44
    • 0028805463 scopus 로고
    • Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures
    • Minghetti L, Levi G. 1995. Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures. J Neurochem 65:2690-2698.
    • (1995) J Neurochem , vol.65 , pp. 2690-2698
    • Minghetti, L.1    Levi, G.2
  • 45
    • 0033822556 scopus 로고    scopus 로고
    • Thrombin-induced activation of cultured rodent microglia
    • Moller T, Hanisch UK, Ransom BR. 2000. Thrombin-induced activation of cultured rodent microglia. J Neurochem 75:1539-1547.
    • (2000) J Neurochem , vol.75 , pp. 1539-1547
    • Moller, T.1    Hanisch, U.K.2    Ransom, B.R.3
  • 46
  • 47
    • 0035881917 scopus 로고    scopus 로고
    • Impaired microglial activation in the brain of IL-18-gene-disrupted mice after neurovirulent influenza A virus infection
    • Mori I, Hossain MJ, Takeda K, Okamura H, Imai Y, Kohsaka S, Kimura Y. 2001. Impaired microglial activation in the brain of IL-18-gene-disrupted mice after neurovirulent influenza A virus infection. Virology 287:163-170.
    • (2001) Virology , vol.287 , pp. 163-170
    • Mori, I.1    Hossain, M.J.2    Takeda, K.3    Okamura, H.4    Imai, Y.5    Kohsaka, S.6    Kimura, Y.7
  • 48
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya S, Sugimoto Y, Ushikubi F. 1999. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79:1193-1226.
    • (1999) Physiol Rev , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 49
    • 0028369990 scopus 로고
    • Microglial cells in the brain of Pleurodeles wald (Urodela, Salamandridae) after wallerian degeneration in the primary visual system using Bandeiraea simplicifolia isolectin B4-cytochemistry
    • Naujoks-Manteuffel C, Niemann U. 1994. Microglial cells in the brain of Pleurodeles wald (Urodela, Salamandridae) after wallerian degeneration in the primary visual system using Bandeiraea simplicifolia isolectin B4-cytochemistry. Glia 10:101-113.
    • (1994) Glia , vol.10 , pp. 101-113
    • Naujoks-Manteuffel, C.1    Niemann, U.2
  • 50
    • 0030825278 scopus 로고    scopus 로고
    • Coexistence of purino- and pyrimidinoceptors on activated rat microglial cells
    • Norenberg W, Cordes A, Blohbaum G, Frohlich R, Illes P. 1997. Coexistence of purino- and pyrimidinoceptors on activated rat microglial cells. Br J Pharmacol 121:1087-1098.
    • (1997) Br J Pharmacol , vol.121 , pp. 1087-1098
    • Norenberg, W.1    Cordes, A.2    Blohbaum, G.3    Frohlich, R.4    Illes, P.5
  • 51
    • 0033824729 scopus 로고    scopus 로고
    • Involvement of Ibain membrane ruffling and phagocytosis of macrophages/microglia
    • Ohsawa K, Imai Y, Kanazawa H, Sasaki Y, Kohsaka S. 2000. Involvement of Ibain membrane ruffling and phagocytosis of macrophages/microglia. J Cell Sci 113:3073-3084.
    • (2000) J Cell Sci , vol.113 , pp. 3073-3084
    • Ohsawa, K.1    Imai, Y.2    Kanazawa, H.3    Sasaki, Y.4    Kohsaka, S.5
  • 52
    • 0032524318 scopus 로고    scopus 로고
    • Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitirc-oxide synthase in rat astrocytes and macrophages
    • Pahan K, Sheikh FG, Namboodiri AM, Singh I. 1998. Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitirc-oxide synthase in rat astrocytes and macrophages. J Biol Chem 273:12219-26.
    • (1998) J Biol Chem , vol.273 , pp. 12219-12226
    • Pahan, K.1    Sheikh, F.G.2    Namboodiri, A.M.3    Singh, I.4
  • 53
    • 0022387412 scopus 로고
    • Inummohistochemical localization of macrophages and microglia in the adult and developing mouse brain
    • Perry VH, Hume DA, Gordon S. 1985. Inummohistochemical localization of macrophages and microglia in the adult and developing mouse brain. Neuroscience 15:313-326.
    • (1985) Neuroscience , vol.15 , pp. 313-326
    • Perry, V.H.1    Hume, D.A.2    Gordon, S.3
  • 54
    • 0023893302 scopus 로고
    • Macrophages and microglia in the nervous system
    • Perry VH, Gordon S. 1988. Macrophages and microglia in the nervous system. Trends Neurosci 11:273-277.
    • (1988) Trends Neurosci , vol.11 , pp. 273-277
    • Perry, V.H.1    Gordon, S.2
  • 55
    • 0025609657 scopus 로고
    • Accessory phenotype and function of macrophages induced by cyclic adenosine monophosphate
    • Peters JH, Borner T, Ruppert J. 1990. Accessory phenotype and function of macrophages induced by cyclic adenosine monophosphate. Int Immunol 2:1195-1202.
    • (1990) Int Immunol , vol.2 , pp. 1195-1202
    • Peters, J.H.1    Borner, T.2    Ruppert, J.3
  • 56
    • 0031606019 scopus 로고    scopus 로고
    • Compartmentalization of PDE-4 and cAMP-dependent protein kinase in neutrophils and macrophages during phagocytosis
    • Pryzwansky KB, Kidao S, Merricks EP. 1998. Compartmentalization of PDE-4 and cAMP-dependent protein kinase in neutrophils and macrophages during phagocytosis. Cell Biochem Biophys 28:251-275.
    • (1998) Cell Biochem Biophys , vol.28 , pp. 251-275
    • Pryzwansky, K.B.1    Kidao, S.2    Merricks, E.P.3
  • 57
    • 0028050415 scopus 로고
    • Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse
    • Raivich G, Moreno-Flores MT, Moller JC, Kreutzberg GW. 1994. Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse. Eur J Neurosci 6:1615-1618.
    • (1994) Eur J Neurosci , vol.6 , pp. 1615-1618
    • Raivich, G.1    Moreno-Flores, M.T.2    Moller, J.C.3    Kreutzberg, G.W.4
  • 58
    • 0032814562 scopus 로고    scopus 로고
    • Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
    • Raivich G, Bohatschek M, Kloss CUA, Werner A, Jones LL, Kreutzberg GW. 1999. Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Rev 30:77-105.
    • (1999) Brain Res Rev , vol.30 , pp. 77-105
    • Raivich, G.1    Bohatschek, M.2    Kloss, C.U.A.3    Werner, A.4    Jones, L.L.5    Kreutzberg, G.W.6
  • 59
    • 0036934895 scopus 로고    scopus 로고
    • Cytotoxic potential of proinflammatory cytokines: Combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse
    • in press
    • Raivich G, Liu ZQ, Kloss CUA, Labow M, Bluethmann H, Bohatschek M. 2002. Cytotoxic potential of proinflammatory cytokines: combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse. Exp Neurol in press.
    • (2002) Exp Neurol
    • Raivich, G.1    Liu, Z.Q.2    Kloss, C.U.A.3    Labow, M.4    Bluethmann, H.5    Bohatschek, M.6
  • 63
    • 0035189588 scopus 로고    scopus 로고
    • Pertussis toxin and lipopolysaccharide influence phagocytosis of Bordetella pertussis by human monocytes
    • Schaeffer LM, Weiss AA. 2001. Pertussis toxin and lipopolysaccharide influence phagocytosis of Bordetella pertussis by human monocytes. Infect Immun 69:7635-7641.
    • (2001) Infect Immun , vol.69 , pp. 7635-7641
    • Schaeffer, L.M.1    Weiss, A.A.2
  • 66
    • 0028676161 scopus 로고
    • Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: Morphology
    • Sievers J, Parwaresch R, Wottge HU. 1994. Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: morphology. Glia 12:245-258.
    • (1994) Glia , vol.12 , pp. 245-258
    • Sievers, J.1    Parwaresch, R.2    Wottge, H.U.3
  • 68
    • 0030769625 scopus 로고    scopus 로고
    • Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation
    • Sontag E, Sontag JM, Garcia A. 1997. Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation. EMBO J 16:5662-5671.
    • (1997) EMBO J , vol.16 , pp. 5662-5671
    • Sontag, E.1    Sontag, J.M.2    Garcia, A.3
  • 69
    • 0024601752 scopus 로고
    • Light microscopic study of degenerating cobalt-filled optic axons in goldfish: Role of microglia and radial glia in debris removal
    • Springer AD, Wilson BR. 1989. Light microscopic study of degenerating cobalt-filled optic axons in goldfish: role of microglia and radial glia in debris removal. J Comp Neurol 282:119-132.
    • (1989) J Comp Neurol , vol.282 , pp. 119-132
    • Springer, A.D.1    Wilson, B.R.2
  • 70
    • 0023213595 scopus 로고
    • Lectin binding by resting and reactive microglia
    • Streit WJ, Kreutzberg GW. 1987. Lectin binding by resting and reactive microglia. J Neurocytol 16:249-260.
    • (1987) J Neurocytol , vol.16 , pp. 249-260
    • Streit, W.J.1    Kreutzberg, G.W.2
  • 71
    • 0024281211 scopus 로고
    • Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin
    • Streit WJ, Kreutzberg GW. 1988. Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin. J Comp Neurol 268:248-263.
    • (1988) J Comp Neurol , vol.268 , pp. 248-263
    • Streit, W.J.1    Kreutzberg, G.W.2
  • 72
    • 0030925772 scopus 로고    scopus 로고
    • Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes
    • Stromhaug PE, Berg TO, Gjoen T, Seglen PO. 1997. Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes. Eur J Cell Biol 73:28-39.
    • (1997) Eur J Cell Biol , vol.73 , pp. 28-39
    • Stromhaug, P.E.1    Berg, T.O.2    Gjoen, T.3    Seglen, P.O.4
  • 74
    • 0025853565 scopus 로고
    • Morphological transformation of microglia in vitro
    • Suzumura A, Marunouchi T, Yamamoto H. 1991. Morphological transformation of microglia in vitro. Brain Res 545:301-306.
    • (1991) Brain Res , vol.545 , pp. 301-306
    • Suzumura, A.1    Marunouchi, T.2    Yamamoto, H.3
  • 75
    • 0029935764 scopus 로고    scopus 로고
    • Microglial ramification requires nondiffusible factors derived from astrocytes
    • Tanaka J, Maeda N. 1996. Microglial ramification requires nondiffusible factors derived from astrocytes. Exp Neurol 137:367-375.
    • (1996) Exp Neurol , vol.137 , pp. 367-375
    • Tanaka, J.1    Maeda, N.2
  • 76
    • 0032189990 scopus 로고    scopus 로고
    • Induction of resting microglia in culture medium devoid of glycine and serine
    • Tanaka J, Toku K, Matsuda S, Sudo S, Fujita H, Sakanaka M, Maeda N. 1998. Induction of resting microglia in culture medium devoid of glycine and serine. Glia 24:198-215.
    • (1998) Glia , vol.24 , pp. 198-215
    • Tanaka, J.1    Toku, K.2    Matsuda, S.3    Sudo, S.4    Fujita, H.5    Sakanaka, M.6    Maeda, N.7
  • 77
    • 0030736771 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 env impairs Fc receptor-mediated phagocytosis via a cyclic adenosine monophosphate-dependent mechanism
    • Thomas CA, Weinberger OK, Ziegler BL, Greenberg S, Schieren I, Silverstein SC, El Khoury J. 1997. Human immunodeficiency virus-1 env impairs Fc receptor-mediated phagocytosis via a cyclic adenosine monophosphate-dependent mechanism. Blood 90:3760-3765.
    • (1997) Blood , vol.90 , pp. 3760-3765
    • Thomas, C.A.1    Weinberger, O.K.2    Ziegler, B.L.3    Greenberg, S.4    Schieren, I.5    Silverstein, S.C.6    El Khoury, J.7
  • 78
    • 0023666950 scopus 로고
    • Immunological and biochemical differentiation of guanyl nucleotide binding proteins: Interaction of Go alpha with rhodopsin, anti-Go alpha polyclonal antibodies, and a monoclonal antibody against transducin alpha subunit and Gi alpha
    • Tsai SC, Adamik R, Kanaho Y, Halpern JL, Moss J. 1987. Immunological and biochemical differentiation of guanyl nucleotide binding proteins: interaction of Go alpha with rhodopsin, anti-Go alpha polyclonal antibodies, and a monoclonal antibody against transducin alpha subunit and Gi alpha. Biochemistry 26:4728-4733.
    • (1987) Biochemistry , vol.26 , pp. 4728-4733
    • Tsai, S.C.1    Adamik, R.2    Kanaho, Y.3    Halpern, J.L.4    Moss, J.5
  • 79
    • 0032982796 scopus 로고    scopus 로고
    • Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density
    • Umeda S, Beamer WG, Takagi K, Naito M, Hayashi S, Yonemitsu H, Yi T, Shultz LD. 1999. Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density. Am J Pathol 155:223-233.
    • (1999) Am J Pathol , vol.155 , pp. 223-233
    • Umeda, S.1    Beamer, W.G.2    Takagi, K.3    Naito, M.4    Hayashi, S.5    Yonemitsu, H.6    Yi, T.7    Shultz, L.D.8
  • 80
    • 0029615413 scopus 로고
    • Microglia in normal and regenerating visual pathways of the tench (Tinca tinca L, 1758; Teleost): A study with tomato lectin
    • Velasco A, Cammos E, Vecino E, Lara JM, Aijon J. 1995. Microglia in normal and regenerating visual pathways of the tench (Tinca tinca L, 1758; Teleost): a study with tomato lectin. Brain Res 705:315-324.
    • (1995) Brain Res , vol.705 , pp. 315-324
    • Velasco, A.1    Cammos, E.2    Vecino, E.3    Lara, J.M.4    Aijon, J.5
  • 81
    • 0019509120 scopus 로고
    • Defective Fc-mediated phagocytosis in C3H/HeJ macrophages: II, correction by cAMP agonists
    • Vogel SN, Weedon LL, Oppenheim JJ, Rosenstreich DL. 1981. Defective Fc-mediated phagocytosis in C3H/HeJ macrophages: II, correction by cAMP agonists. J Immunol 126:441-445.
    • (1981) J Immunol , vol.126 , pp. 441-445
    • Vogel, S.N.1    Weedon, L.L.2    Oppenheim, J.J.3    Rosenstreich, D.L.4
  • 84
    • 0032983068 scopus 로고    scopus 로고
    • In vitro-staining specificity of the antibody 5-D-4 for microglia but not for monocytes and macrophages indicates that microglia are a unique subgroup of the myelomonocytic lineage
    • Wilms H, Wollmer MA, Sievers J. 1999. In vitro-staining specificity of the antibody 5-D-4 for microglia but not for monocytes and macrophages indicates that microglia are a unique subgroup of the myelomonocytic lineage. J Neuroimmunol 98:89-95.
    • (1999) J Neuroimmunol , vol.98 , pp. 89-95
    • Wilms, H.1    Wollmer, M.A.2    Sievers, J.3
  • 86
    • 0033214196 scopus 로고    scopus 로고
    • Thapsigargin induces microglial transformation from ameboid to ramified type in vitro
    • Yagi R, Tanaka S, Koike T. 2000. Thapsigargin induces microglial transformation from ameboid to ramified type in vitro. Glia 28:49-52.
    • (2000) Glia , vol.28 , pp. 49-52
    • Yagi, R.1    Tanaka, S.2    Koike, T.3
  • 87
    • 0036346580 scopus 로고    scopus 로고
    • Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis
    • Zakany R, Szucs K, Bako E, Felszeghy S, Czifra G, Biro T, Modis L, Gergely P. 2002. Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis. Exp Cell Res 275:1-8.
    • (2002) Exp Cell Res , vol.275 , pp. 1-8
    • Zakany, R.1    Szucs, K.2    Bako, E.3    Felszeghy, S.4    Czifra, G.5    Biro, T.6    Modis, L.7    Gergely, P.8
  • 88
    • 0036172694 scopus 로고    scopus 로고
    • Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: Comparison with other types of cAMP-elevating agents
    • Zhang B, Yang L, Konishi Y, Maeda N, Sakanaka M, Tanaka J. 2002. Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: comparison with other types of cAMP-elevating agents. Neuropharmacology 42:262-269.
    • (2002) Neuropharmacology , vol.42 , pp. 262-269
    • Zhang, B.1    Yang, L.2    Konishi, Y.3    Maeda, N.4    Sakanaka, M.5    Tanaka, J.6


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