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Volumn 21, Issue 1, 2003, Pages 79-89

Hematopoietic recovery following autologous bone marrow transplantation in a nonhuman primate: Effect of variation in treatment schedule with PEG-rHuMGDF

Author keywords

Bone marrow transplant; Hematopoietic; Nonhuman primate; PEG rHuMGDF; Platelet

Indexed keywords

CYTOKINE; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; MYELOABLATIVE AGENT; PEGYLATED RECOMBINANT HUMAN MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; UNCLASSIFIED DRUG;

EID: 0037237460     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.21-1-79     Document Type: Article
Times cited : (14)

References (73)
  • 1
    • 0026504705 scopus 로고
    • Effect of peripheral blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high dose chemotherapy
    • Sheridan WP, Begley G, Juttner CA et al. Effect of peripheral blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high dose chemotherapy. Lancet 1992;339:640-644.
    • (1992) Lancet , vol.339 , pp. 640-644
    • Sheridan, W.P.1    Begley, G.2    Juttner, C.A.3
  • 2
    • 0023222563 scopus 로고
    • Peripheral blood stem cells collected in very early remission produce rapid and sustained autologous haemopoietic reconstitution in acute non-lymphoblastic leukemia
    • To LB, Dyson PG, Branford AL. Peripheral blood stem cells collected in very early remission produce rapid and sustained autologous haemopoietic reconstitution in acute non-lymphoblastic leukemia. Bone Marrow Transplant 1987;2:103-108.
    • (1987) Bone Marrow Transplant , vol.2 , pp. 103-108
    • To, L.B.1    Dyson, P.G.2    Branford, A.L.3
  • 3
    • 0027247497 scopus 로고
    • Rapid and sustained hematopoietic reconstitution by peripheral blood stem cell infusion alone following high-dose chemotherapy
    • Schwartzberg L, Birch R, Blanco R et al. Rapid and sustained hematopoietic reconstitution by peripheral blood stem cell infusion alone following high-dose chemotherapy. Bone Marrow Transplant 1993;11:369-374.
    • (1993) Bone Marrow Transplant , vol.11 , pp. 369-374
    • Schwartzberg, L.1    Birch, R.2    Blanco, R.3
  • 4
    • 0027405268 scopus 로고
    • Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy
    • Chao NJ, Schriber JR, Grimes K et al. Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy. Blood 1993;81:2031-2035.
    • (1993) Blood , vol.81 , pp. 2031-2035
    • Chao, N.J.1    Schriber, J.R.2    Grimes, K.3
  • 5
    • 0018190618 scopus 로고
    • Successful engraftment of cryopreserved autologous bone marrow in patients with malignant lymphoma
    • Appelbaum FR, Herzig GP, Ziegler JL et al. Successful engraftment of cryopreserved autologous bone marrow in patients with malignant lymphoma. Blood 1978;52:85-95.
    • (1978) Blood , vol.52 , pp. 85-95
    • Appelbaum, F.R.1    Herzig, G.P.2    Ziegler, J.L.3
  • 6
    • 0026591775 scopus 로고
    • Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants
    • To LB, Roberts MM, Haylock DN et al. Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants. Bone Marrow Transplant 1992;9:277-284.
    • (1992) Bone Marrow Transplant , vol.9 , pp. 277-284
    • To, L.B.1    Roberts, M.M.2    Haylock, D.N.3
  • 7
    • 0024538025 scopus 로고
    • Engraftment in 86 patients with lymphoid malignancy after autologous marrow transplantation
    • Hill RS, Mazza P, Amos D. Engraftment in 86 patients with lymphoid malignancy after autologous marrow transplantation. Bone Marrow Transplant 1989;4:69-74.
    • (1989) Bone Marrow Transplant , vol.4 , pp. 69-74
    • Hill, R.S.1    Mazza, P.2    Amos, D.3
  • 8
    • 1842417173 scopus 로고    scopus 로고
    • A prospective randomized trial of buffy coat versus CD34-selected autologous bone marrow support in high-risk breast cancer patients receiving high-dose chemotherapy
    • Shpall EJ, LeMaistre CF, Holland K et al. A prospective randomized trial of buffy coat versus CD34-selected autologous bone marrow support in high-risk breast cancer patients receiving high-dose chemotherapy. Blood 1997;90:4313-4320.
    • (1997) Blood , vol.90 , pp. 4313-4320
    • Shpall, E.J.1    LeMaistre, C.F.2    Holland, K.3
  • 9
    • 0027191820 scopus 로고
    • High-dose chemotherapy and autologous bone marrow support after standard-dose adjuvant therapy for high-risk primary breast cancer
    • Peters WP, Ross M, Vredenburgh JJ et al. High-dose chemotherapy and autologous bone marrow support after standard-dose adjuvant therapy for high-risk primary breast cancer. J Clin Oncol 1993;11:1132-1143.
    • (1993) J Clin Oncol , vol.11 , pp. 1132-1143
    • Peters, W.P.1    Ross, M.2    Vredenburgh, J.J.3
  • 10
    • 0028779536 scopus 로고
    • Bone marrow transplantation
    • Armitage JO. Bone marrow transplantation. N Engl J Med 1994;330:827-838.
    • (1994) N Engl J Med , vol.330 , pp. 827-838
    • Armitage, J.O.1
  • 11
    • 0023392425 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model
    • Nienhuis AW, Donahue RE, Karlsson S et al. Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest 1987;80:573-577.
    • (1987) J Clin Invest , vol.80 , pp. 573-577
    • Nienhuis, A.W.1    Donahue, R.E.2    Karlsson, S.3
  • 12
    • 0023555579 scopus 로고
    • The effect of recombinant GM-CSF on the recovery of monkeys transplanted with autologous bone marrow
    • Monroy RL, Skelly RR, MacVittie TJ et al. The effect of recombinant GM-CSF on the recovery of monkeys transplanted with autologous bone marrow. Blood 1987;70:1696-1699.
    • (1987) Blood , vol.70 , pp. 1696-1699
    • Monroy, R.L.1    Skelly, R.R.2    MacVittie, T.J.3
  • 13
    • 0026428605 scopus 로고
    • Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer
    • Nemunaitis J, Rabinowe SN, Singer JW et al. Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer. N Engl J Med 1991;324:1773-1778.
    • (1991) N Engl J Med , vol.324 , pp. 1773-1778
    • Nemunaitis, J.1    Rabinowe, S.N.2    Singer, J.W.3
  • 14
    • 0344834092 scopus 로고
    • Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation
    • Sheridan WP, Morstyn G, Wolf M et al. Granulocyte colony-stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. Lancet 1989;2:891-895.
    • (1989) Lancet , vol.2 , pp. 891-895
    • Sheridan, W.P.1    Morstyn, G.2    Wolf, M.3
  • 15
    • 0028224131 scopus 로고
    • Placebo-controlled phase III trial of lenograstim in bone-marrow transplantation
    • Published erratum in Lancet 1994 26;343:804
    • Gisselbrecht C, Prentice HG, Bacigalupo A et al. Placebo-controlled phase III trial of lenograstim in bone-marrow transplantation [Published erratum in Lancet 1994 26;343:804]. Lancet 1994;343:696-700.
    • (1994) Lancet , vol.343 , pp. 696-700
    • Gisselbrecht, C.1    Prentice, H.G.2    Bacigalupo, A.3
  • 16
    • 0024833397 scopus 로고
    • Recombinant human granulocyte colony-stimulating factor hastens granulocyte recovery after high-dose chemotherapy and autologous bone marrow transplantation in Hodgkin's disease
    • Taylor KM, Jagannath S, Spitzer G et al. Recombinant human granulocyte colony-stimulating factor hastens granulocyte recovery after high-dose chemotherapy and autologous bone marrow transplantation in Hodgkin's disease. J Clin Oncol 1989;7:1791-1799.
    • (1989) J Clin Oncol , vol.7 , pp. 1791-1799
    • Taylor, K.M.1    Jagannath, S.2    Spitzer, G.3
  • 17
    • 0031024117 scopus 로고    scopus 로고
    • An analysis of the effects of combined treatment with RmGM-CSF and PEG-RHuMGDF in murine bone marrow transplant recipients
    • Molineux G, Hartley C, McElroy P et al. An analysis of the effects of combined treatment with RmGM-CSF and PEG-RHuMGDF in murine bone marrow transplant recipients. STEM CELLS 1997;15:43-49.
    • (1997) Stem Cells , vol.15 , pp. 43-49
    • Molineux, G.1    Hartley, C.2    McElroy, P.3
  • 18
    • 0029839244 scopus 로고    scopus 로고
    • Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation
    • Molineux G, Hartley C, McElroy P et al. Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation. Blood 1996;88:1509-1514.
    • (1996) Blood , vol.88 , pp. 1509-1514
    • Molineux, G.1    Hartley, C.2    McElroy, P.3
  • 19
    • 0030443702 scopus 로고    scopus 로고
    • Improvement of thrombocytopenia following bone marrow transplantation by pegylated recombinant human megakaryocyte growth and development factor in mice
    • Kabaya K, Shibuya K, Torii Y et al. Improvement of thrombocytopenia following bone marrow transplantation by pegylated recombinant human megakaryocyte growth and development factor in mice. Bone Marrow Transplant 1996;18:1035-1041.
    • (1996) Bone Marrow Transplant , vol.18 , pp. 1035-1041
    • Kabaya, K.1    Shibuya, K.2    Torii, Y.3
  • 20
    • 0028787175 scopus 로고
    • Accelerated reconsitufion of platelets and erythrocytes after syngenic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice
    • Fibbe WE, Heemskerk DP, Laterveer L et al. Accelerated reconsitufion of platelets and erythrocytes after syngenic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice. Blood 1995;86:3308-3313.
    • (1995) Blood , vol.86 , pp. 3308-3313
    • Fibbe, W.E.1    Heemskerk, D.P.2    Laterveer, L.3
  • 21
    • 0030929124 scopus 로고    scopus 로고
    • Lack of efficacy of thrombopoietin and granulocyte colony-stimulating factor after high dose total-body irradiation and autologous stem cell or bone marrow transplantation in rhesus monkeys
    • Neelis KJ, Dubbelman YD, Wognum AW et al. Lack of efficacy of thrombopoietin and granulocyte colony- stimulating factor after high dose total-body irradiation and autologous stem cell or bone marrow transplantation in rhesus monkeys. Exp Hematol 1997;25:1094-1103.
    • (1997) Exp Hematol , vol.25 , pp. 1094-1103
    • Neelis, K.J.1    Dubbelman, Y.D.2    Wognum, A.W.3
  • 22
    • 0003281961 scopus 로고    scopus 로고
    • Hematopoietic recovery following autologous bone marrow transplantation: Effect of pretreatment and/or therapeutic administration of PEG-rHuMGDF
    • Farese AM, Stead RB, Roskos L et al. Hematopoietic recovery following autologous bone marrow transplantation: effect of pretreatment and/or therapeutic administration of PEG-rHuMGDF. Blood 1996;88:600a.
    • (1996) Blood , vol.88
    • Farese, A.M.1    Stead, R.B.2    Roskos, L.3
  • 23
    • 0036053616 scopus 로고    scopus 로고
    • Effect of C-Mpl ligands after total body irradiation (TBI) with and without allogeneic hematopoietic stem cell transplantation: Low-dose TBI does not prevent sensitization
    • Nash RA, Takatu A, Feng Z et al. Effect of C-Mpl ligands after total body irradiation (TBI) with and without allogeneic hematopoietic stem cell transplantation: low-dose TBI does not prevent sensitization. Biol Blood Marrow Transplant 2002;8:360-367.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 360-367
    • Nash, R.A.1    Takatu, A.2    Feng, Z.3
  • 24
    • 0030799430 scopus 로고    scopus 로고
    • The efficacy of single-dose administration of thrombopoietin with coadministration of either granulocyte/macrophage or granulocyte colony-stimulating factor in myelosuppressed rhesus monkeys
    • Neelis KJ, Hartong SC, Egeland T et al. The efficacy of single-dose administration of thrombopoietin with coadministration of either granulocyte/macrophage or granulocyte colony-stimulating factor in myelosuppressed rhesus monkeys. Blood 1997;90:2565-2573.
    • (1997) Blood , vol.90 , pp. 2565-2573
    • Neelis, K.J.1    Hartong, S.C.2    Egeland, T.3
  • 25
    • 0030882894 scopus 로고    scopus 로고
    • Simultaneous administration of TPO and G-CSF after cytoreductive treatment of rhesus monkeys prevents thrombocytopenia, accelerates platelet and red cell reconstitution, alleviates neutropenia, and promotes the recovery of immature bone marrow cells
    • Neelis KJ, Dubbelman YD, Qingliang L et al. Simultaneous administration of TPO and G-CSF after cytoreductive treatment of rhesus monkeys prevents thrombocytopenia, accelerates platelet and red cell reconstitution, alleviates neutropenia, and promotes the recovery of immature bone marrow cells. Exp Hematol 1997;25:1084-1093.
    • (1997) Exp Hematol , vol.25 , pp. 1084-1093
    • Neelis, K.J.1    Dubbelman, Y.D.2    Qingliang, L.3
  • 26
    • 0029963122 scopus 로고    scopus 로고
    • Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia
    • Farese AM, Hunt P, Grab LB et al. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia. J Clin Invest 1996;97:2145-2151.
    • (1996) J Clin Invest , vol.97 , pp. 2145-2151
    • Farese, A.M.1    Hunt, P.2    Grab, L.B.3
  • 27
    • 0029150347 scopus 로고
    • Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy
    • Kaushansky K, Broudy VC, Grossmann A et al. Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. J Clin Invest 1995;96:1683-1687.
    • (1995) J Clin Invest , vol.96 , pp. 1683-1687
    • Kaushansky, K.1    Broudy, V.C.2    Grossmann, A.3
  • 28
    • 0032704722 scopus 로고    scopus 로고
    • PEG-RHuMGDF promotes multilineage hematopoietic recovery in myelosuppressed mice
    • Ulich TR, del Castillo JD, Senaldi G et al. PEG-RHuMGDF promotes multilineage hematopoietic recovery in myelosuppressed mice. Exp Hematol 1999;27:1776-1781.
    • (1999) Exp Hematol , vol.27 , pp. 1776-1781
    • Ulich, T.R.1    Del Castillo, J.D.2    Senaldi, G.3
  • 29
    • 0029051730 scopus 로고
    • Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice
    • Ulich TR, del Castillo J, Yin S et al. Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice. Blood 1995;86:971-976.
    • (1995) Blood , vol.86 , pp. 971-976
    • Ulich, T.R.1    Del Castillo, J.2    Yin, S.3
  • 30
    • 9544248772 scopus 로고    scopus 로고
    • Effect of recombinant human thrombopoietin in nonhuman primates with chemotherapy-induced thrombocytopenia
    • Akahori H, Shibuya A, Obuchi M et al. Effect of recombinant human thrombopoietin in nonhuman primates with chemotherapy-induced thrombocytopenia. Br J Haematol 1996;94:722-728.
    • (1996) Br J Haematol , vol.94 , pp. 722-728
    • Akahori, H.1    Shibuya, A.2    Obuchi, M.3
  • 31
    • 0030307632 scopus 로고    scopus 로고
    • In vivo biological effects of various forms of thrombopoietin in a murine model of transient thrombocytopenia
    • Thomas GR, Thibodeaux H, Erret CJ et al. In vivo biological effects of various forms of thrombopoietin in a murine model of transient thrombocytopenia. STEM CELLS 1996;14(suppl 1):246-255.
    • (1996) Stem Cells , vol.14 , Issue.SUPPL. 1 , pp. 246-255
    • Thomas, G.R.1    Thibodeaux, H.2    Erret, C.J.3
  • 32
    • 0031965018 scopus 로고    scopus 로고
    • Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice
    • Shibuya K, Akahori H, Takahashi K et al. Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice. Blood 1998;91:37-45.
    • (1998) Blood , vol.91 , pp. 37-45
    • Shibuya, K.1    Akahori, H.2    Takahashi, K.3
  • 33
    • 0029829805 scopus 로고    scopus 로고
    • Effects of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia induced by a new myelosuppressive chemotherapy regimen in mice
    • Akahori H, Shibuya A, Ozai M et al. Effects of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia induced by a new myelosuppressive chemotherapy regimen in mice. STEM CELLS 1996;14:678-689.
    • (1996) Stem Cells , vol.14 , pp. 678-689
    • Akahori, H.1    Shibuya, A.2    Ozai, M.3
  • 34
    • 0032228105 scopus 로고    scopus 로고
    • The combined administration of daniplestim and MpL ligand augments the hematopoietic reconstitution observed with single cytokine administration in a nonhuman primate model of myelosuppression
    • Farese A, MacVittie TJ, Lind LB et al. The combined administration of daniplestim and MpL ligand augments the hematopoietic reconstitution observed with single cytokine administration in a nonhuman primate model of myelosuppression. STEM CELLS 1998;16(suppl 2):143-154.
    • (1998) Stem Cells , vol.16 , Issue.SUPPL. 2 , pp. 143-154
    • Farese, A.1    MacVittie, T.J.2    Lind, L.B.3
  • 35
    • 0029807901 scopus 로고    scopus 로고
    • Recombinant human ligand for MPL, megakaryocyte growth and development factor (MGDF), stimulates thrombopoiesis in vivo in normal and myelosuppressed baboons
    • Andrews RG, Winkler A, Myerson D et al. Recombinant human ligand for MPL, megakaryocyte growth and development factor (MGDF), stimulates thrombopoiesis in vivo in normal and myelosuppressed baboons. STEM CELLS 1996;14:661-677.
    • (1996) Stem Cells , vol.14 , pp. 661-677
    • Andrews, R.G.1    Winkler, A.2    Myerson, D.3
  • 36
    • 0034895667 scopus 로고    scopus 로고
    • Promegapoietin-la, an engineered chimeric IL-3 and Mpl-L receptor agonist, stimulates hematopoietic recovery in conventional and abbreviated schedules following radiation-induced myelosuppression in nonhuman primates
    • Farese AM, Smith WG, Giri JG et al. Promegapoietin-la, an engineered chimeric IL-3 and Mpl-L receptor agonist, stimulates hematopoietic recovery in conventional and abbreviated schedules following radiation-induced myelosuppression in nonhuman primates. STEM CELLS 2001;19:329-338.
    • (2001) Stem Cells , vol.19 , pp. 329-338
    • Farese, A.M.1    Smith, W.G.2    Giri, J.G.3
  • 37
    • 10344235968 scopus 로고    scopus 로고
    • Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-RHuMGDF) in patients with advanced cancer
    • Basser RL, Rasko JE, Clarke K et al. Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-RHuMGDF) in patients with advanced cancer. Lancet 1996;348:1279-1281.
    • (1996) Lancet , vol.348 , pp. 1279-1281
    • Basser, R.L.1    Rasko, J.E.2    Clarke, K.3
  • 38
    • 0031049879 scopus 로고    scopus 로고
    • Effects of polyethylene glycol -conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer
    • Fanucchi M, Glaspy J, Crawford J et al. Effects of polyethylene glycol -conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer. N Engl J Med 1997;336:404-409.
    • (1997) N Engl J Med , vol.336 , pp. 404-409
    • Fanucchi, M.1    Glaspy, J.2    Crawford, J.3
  • 39
    • 17944389931 scopus 로고    scopus 로고
    • Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer
    • Basser RL, Rasko JEJ, Clarke K et al. Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer. Blood 1997;89:3118-3128.
    • (1997) Blood , vol.89 , pp. 3118-3128
    • Basser, R.L.1    Rasko, J.E.J.2    Clarke, K.3
  • 40
    • 0034050651 scopus 로고    scopus 로고
    • Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic malignancy
    • Vadhan-Raj S, Verschraegen CF, Bueso-Ramos C et al. Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic malignancy. Ann Intern Med 2000;132:364-368.
    • (2000) Ann Intern Med , vol.132 , pp. 364-368
    • Vadhan-Raj, S.1    Verschraegen, C.F.2    Bueso-Ramos, C.3
  • 41
    • 10344238601 scopus 로고    scopus 로고
    • Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation
    • O'Malley CJ, Rasko JE, Basser RL et al. Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation. Blood 1996;88:3288-3298.
    • (1996) Blood , vol.88 , pp. 3288-3298
    • O'Malley, C.J.1    Rasko, J.E.2    Basser, R.L.3
  • 42
    • 0034655649 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia
    • Schiffer CA, Miller K, Larson RA et al. A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia. Blood 2000;95:2530-2534.
    • (2000) Blood , vol.95 , pp. 2530-2534
    • Schiffer, C.A.1    Miller, K.2    Larson, R.A.3
  • 43
    • 0033485568 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-RHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia
    • Archimbaud E, Ottmann OG, Liu-Yin JA et al. A randomized, double-blinded, placebo controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-RHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia. Blood 1999;94:3694-3701.
    • (1999) Blood , vol.94 , pp. 3694-3701
    • Archimbaud, E.1    Ottmann, O.G.2    Liu-Yin, J.A.3
  • 44
    • 0001690215 scopus 로고    scopus 로고
    • Effect of pegylated recombinant megakaryocyte growth and development factor (PEG-RHuMGDF) before high dose chemotherapy with peripheral blood progenitor cell (PBPC) support
    • Glaspy J, Vredenburgh JJ, Demetri GD et al. Effect of pegylated recombinant megakaryocyte growth and development factor (PEG-RHuMGDF) before high dose chemotherapy with peripheral blood progenitor cell (PBPC) support. Blood 1997;90:580a.
    • (1997) Blood , vol.90
    • Glaspy, J.1    Vredenburgh, J.J.2    Demetri, G.D.3
  • 45
    • 85036702889 scopus 로고    scopus 로고
    • Schedule effect of recombinant human thrombopoietin (rhTPO) in attenuating thrombocytopenia in patients receiving dose intensive chemotherapy with adriamycin (A) and ifosfamide (I)
    • Vadhan-Raj S, Patel S, Broxmeyer H et al. Schedule effect of recombinant human thrombopoietin (rhTPO) in attenuating thrombocytopenia in patients receiving dose intensive chemotherapy with adriamycin (A) and ifosfamide (I). Blood 2000;96:455a.
    • (2000) Blood , vol.96
    • Vadhan-Raj, S.1    Patel, S.2    Broxmeyer, H.3
  • 46
    • 0033631018 scopus 로고    scopus 로고
    • A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation
    • Nash RA, Kurzrock R, DiPersio J et al. A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2000;6:25-34.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 25-34
    • Nash, R.A.1    Kurzrock, R.2    DiPersio, J.3
  • 47
    • 0033709243 scopus 로고    scopus 로고
    • Use of PEG-RHuMGDF in platelet engraftment after autologous stem cell transplantation
    • Fields KK, Crump M, Bence-Bruckler I et al. Use of PEG-RHuMGDF in platelet engraftment after autologous stem cell transplantation. Bone Marrow Transplant 2000;26:1083-1088.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 1083-1088
    • Fields, K.K.1    Crump, M.2    Bence-Bruckler, I.3
  • 48
    • 0033930709 scopus 로고    scopus 로고
    • Phase I study of pegylated recombinant human megkaryocyte growth and development factor (PEG-RHuMGDF) in breast cancer patients after autologous peripheral blood progenitor cell (PBPC) transplantation
    • Bolwell B, Vredenburgh J, Overmoyer B et al. Phase I study of pegylated recombinant human megkaryocyte growth and development factor (PEG-RHuMGDF) in breast cancer patients after autologous peripheral blood progenitor cell (PBPC) transplantation. Bone Marrow Transplant 2000;26:141-145.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 141-145
    • Bolwell, B.1    Vredenburgh, J.2    Overmoyer, B.3
  • 49
    • 17744390344 scopus 로고    scopus 로고
    • Recombinant human thrombopoietin (RhTPO) after autologous bone marrow transplantation: A phase I pharmacokinetic and pharmacodynamic study
    • Wolff SN, Herzig R, Lynch J et al. Recombinant human thrombopoietin (RhTPO) after autologous bone marrow transplantation: a phase I pharmacokinetic and pharmacodynamic study. Bone Marrow Transplant 2001;27:261-268.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 261-268
    • Wolff, S.N.1    Herzig, R.2    Lynch, J.3
  • 50
    • 0004857866 scopus 로고    scopus 로고
    • A cytokinetic model of platelet (PLT) production and destruction following administration of PEG-rHuMGDF
    • Roskos L, Stead R, Harker L et al. A cytokinetic model of platelet (PLT) production and destruction following administration of PEG-rHuMGDF. Blood 1997;90:171a.
    • (1997) Blood , vol.90
    • Roskos, L.1    Stead, R.2    Harker, L.3
  • 51
    • 0034656323 scopus 로고    scopus 로고
    • Effect of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers
    • Harker LA, Roskos LK, Marzec UM et al. Effect of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers. Blood 2000;95:2514-2522.
    • (2000) Blood , vol.95 , pp. 2514-2522
    • Harker, L.A.1    Roskos, L.K.2    Marzec, U.M.3
  • 52
    • 0029097145 scopus 로고
    • Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
    • Mackarehtschian K, Hardin JD, Moore KA et al. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 1995;3:147-161.
    • (1995) Immunity , vol.3 , pp. 147-161
    • Mackarehtschian, K.1    Hardin, J.D.2    Moore, K.A.3
  • 53
    • 0035187822 scopus 로고    scopus 로고
    • A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques
    • Farese AM, Casey DB, Vigneulle RM et al. A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques. STEM CELLS 2001;19:514-521.
    • (2001) Stem Cells , vol.19 , pp. 514-521
    • Farese, A.M.1    Casey, D.B.2    Vigneulle, R.M.3
  • 54
    • 0001690214 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients (Pts) following autologous bone marrow transplantation (ABMT)
    • Beveridge R, Schuster M, Waller E et al. Randomized, double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients (Pts) following autologous bone marrow transplantation (ABMT). Blood 1997;90:580a.
    • (1997) Blood , vol.90
    • Beveridge, R.1    Schuster, M.2    Waller, E.3
  • 55
    • 0003216382 scopus 로고    scopus 로고
    • Schedule-dependent reduction in thrombocytopenia by recombinant human thrombopoietin (rhTPO) in patients with sarcoma receiving high dose chemotherapy (CT) with adriamycin (A) and ifosfamide (I)
    • Vadhan-Raj S, Patel S, Broxmeyer H et al. Schedule-dependent reduction in thrombocytopenia by recombinant human thrombopoietin (rhTPO) in patients with sarcoma receiving high dose chemotherapy (CT) with adriamycin (A) and ifosfamide (I). Proc Am Soc Clin Oncol 1999;18:52a.
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Vadhan-Raj, S.1    Patel, S.2    Broxmeyer, H.3
  • 56
    • 0033065969 scopus 로고    scopus 로고
    • Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation
    • Mouthon MA, Van der Meeren A, Gaugler MH et al. Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation. Int J Radiat Oncol Biol Phys 1999;43:867-875.
    • (1999) Int J Radiat Oncol Biol Phys , vol.43 , pp. 867-875
    • Mouthon, M.A.1    Van der Meeren, A.2    Gaugler, M.H.3
  • 57
    • 0035496922 scopus 로고    scopus 로고
    • mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis
    • Pestina TI, Cleveland JL, Yang C et al. mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis. Blood 2001;98:2084-2090.
    • (2001) Blood , vol.98 , pp. 2084-2090
    • Pestina, T.I.1    Cleveland, J.L.2    Yang, C.3
  • 58
    • 0032227134 scopus 로고    scopus 로고
    • The efficacy of recombinant TPO in murine and nonhuman primate models for myelosuppression and stem cell transplantation
    • Wagemaker G, Neelis KJ, Hartong SC et al. The efficacy of recombinant TPO in murine and nonhuman primate models for myelosuppression and stem cell transplantation. STEM CELLS 1998;16(suppl 2):127-141.
    • (1998) Stem Cells , vol.16 , Issue.SUPPL. 2 , pp. 127-141
    • Wagemaker, G.1    Neelis, K.J.2    Hartong, S.C.3
  • 59
    • 0029858989 scopus 로고    scopus 로고
    • Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro
    • Borge OJ, Ramsfjell V, Veiby OP et al. Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro. Blood 1996;88:2859-2870.
    • (1996) Blood , vol.88 , pp. 2859-2870
    • Borge, O.J.1    Ramsfjell, V.2    Veiby, O.P.3
  • 60
    • 0030823542 scopus 로고    scopus 로고
    • - bone marrow cells with multilineage potential at the single-cell level: Key role of thrombopoietin
    • - bone marrow cells with multilineage potential at the single-cell level: key role of thrombopoietin. Blood 1997;90:2282-2292.
    • (1997) Blood , vol.90 , pp. 2282-2292
    • Borge, O.J.1    Ramsfjell, V.2    Cui, L.3
  • 61
    • 0003293589 scopus 로고
    • Effect of delayed administration of recombinant human megakaryocyte growth and development factor on hematopoietic reconstitution in nonhuman primates following radiation-induced marrow aplasia
    • MacVittie TJ, Farese AM, Grab LB et al. Effect of delayed administration of recombinant human megakaryocyte growth and development factor on hematopoietic reconstitution in nonhuman primates following radiation-induced marrow aplasia. Exp Hematol 1995;23:830a.
    • (1995) Exp Hematol , vol.23
    • MacVittie, T.J.1    Farese, A.M.2    Grab, L.B.3
  • 62
    • 0029770391 scopus 로고    scopus 로고
    • In vivo adenovirus vector-mediated transfer of the human thrombopoietin cdna maintains platelet levels during radiation- and chemotherapy-induced bone marrow suppression
    • Ohwada A, Rafii S, Moore MA et al. In vivo adenovirus vector-mediated transfer of the human thrombopoietin cdna maintains platelet levels during radiation- and chemotherapy-induced bone marrow suppression. Blood 1996;88:778.
    • (1996) Blood , vol.88 , pp. 778
    • Ohwada, A.1    Rafii, S.2    Moore, M.A.3
  • 63
    • 0036330339 scopus 로고    scopus 로고
    • Thrombopoietin expands hematopoietic stem cells after transplantation
    • Fox N, Priestley GV, Papayannopoulou T et al. Thrombopoietin expands hematopoietic stem cells after transplantation. J Clin Invest 2002;110:389-394.
    • (2002) J Clin Invest , vol.110 , pp. 389-394
    • Fox, N.1    Priestley, G.V.2    Papayannopoulou, T.3
  • 64
    • 0032227226 scopus 로고    scopus 로고
    • Endogenous TPO (ETPO) levels in health and disease: Possible clues for therapeutic intervention
    • Nichol JL. Endogenous TPO (ETPO) levels in health and disease: possible clues for therapeutic intervention. STEM CELLS 1998;16(suppl 2):165-175.
    • (1998) Stem Cells , vol.16 , Issue.SUPPL. 2 , pp. 165-175
    • Nichol, J.L.1
  • 65
    • 0029865443 scopus 로고    scopus 로고
    • Regulation of thrombopoietin levels by C-Mpl-mediated binding to platelets
    • Fielder PJ, Gurney AL, Stefanich E et al. Regulation of thrombopoietin levels by C-Mpl-mediated binding to platelets. Blood 1996;87:2154-2161.
    • (1996) Blood , vol.87 , pp. 2154-2161
    • Fielder, P.J.1    Gurney, A.L.2    Stefanich, E.3
  • 66
    • 0029030356 scopus 로고
    • The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit
    • Kuter DJ, Rosenberg RD. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood 1995;85:2720-2730.
    • (1995) Blood , vol.85 , pp. 2720-2730
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 67
    • 0029881744 scopus 로고    scopus 로고
    • Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction
    • Emmons RV, Reid DM, Cohen RL et al. Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. Blood 1996;87:4068-4071.
    • (1996) Blood , vol.87 , pp. 4068-4071
    • Emmons, R.V.1    Reid, D.M.2    Cohen, R.L.3
  • 68
    • 17144456144 scopus 로고    scopus 로고
    • Serum thrombopoietin levels in patients undergoing autologous peripheral blood stem cell transplantation
    • Shimazaki C, Inaba T, Uchiyama H et al. Serum thrombopoietin levels in patients undergoing autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 1997;19:771-775.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 771-775
    • Shimazaki, C.1    Inaba, T.2    Uchiyama, H.3
  • 69
    • 0021343092 scopus 로고
    • The megakaryocyte DNA content and platelet formation after the sublethal whole body irradiation of rats
    • Tanum G. The megakaryocyte DNA content and platelet formation after the sublethal whole body irradiation of rats. Blood 1984;63:917-920.
    • (1984) Blood , vol.63 , pp. 917-920
    • Tanum, G.1
  • 70
    • 0030068687 scopus 로고    scopus 로고
    • Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates
    • Harker LA, Hunt P, Marzec UM et al. Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates. Blood 1996;87:1833-1844.
    • (1996) Blood , vol.87 , pp. 1833-1844
    • Harker, L.A.1    Hunt, P.2    Marzec, U.M.3
  • 71
    • 0028114126 scopus 로고
    • Cytokine production by primary bone marrow megakaryocytes
    • Jiang S, Levine JD, Fu Y et al. Cytokine production by primary bone marrow megakaryocytes. Blood 1994;84:4151-4156.
    • (1994) Blood , vol.84 , pp. 4151-4156
    • Jiang, S.1    Levine, J.D.2    Fu, Y.3
  • 72
    • 0028985440 scopus 로고
    • Secretion of cytokines (Interleukins-1, -3, and -6 and granulocyte macrophage colony-stimulating factor) by normal human bone marrow megakaryocytes
    • Wickenhauser C, Lorenzen J, Thiele J et al. Secretion of cytokines (Interleukins-1, -3, and -6 and granulocyte macrophage colony-stimulating factor) by normal human bone marrow megakaryocytes. Blood 1995;85:685-691.
    • (1995) Blood , vol.85 , pp. 685-691
    • Wickenhauser, C.1    Lorenzen, J.2    Thiele, J.3
  • 73
    • 0030020395 scopus 로고    scopus 로고
    • Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation
    • Nagahisa H, Nagata Y, Ohnuki T et al. Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation. Blood 1996;87:1309-1316.
    • (1996) Blood , vol.87 , pp. 1309-1316
    • Nagahisa, H.1    Nagata, Y.2    Ohnuki, T.3


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