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Volumn 9, Issue 1, 2003, Pages 27-32

Therapeutic dendritic-cell vaccine for simian aids

Author keywords

[No Author keywords available]

Indexed keywords

INACTIVATED VIRUS VACCINE; INACTIVATED WHOLE VIRUS PULSED DENDRITIC CELL VACCINE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS RNA;

EID: 0037234103     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm806     Document Type: Article
Times cited : (219)

References (37)
  • 1
    • 0036530017 scopus 로고    scopus 로고
    • Persistent numbers of tetramer(+) CD8(+) T cells, but loss of interferon-γ(+) HIV-specific T cells during progression to AIDS
    • Kostense, S. et al. Persistent numbers of tetramer(+) CD8(+) T cells, but loss of interferon-γ(+) HIV-specific T cells during progression to AIDS. Blood 99, 2505-2511 (2002).
    • (2002) Blood , vol.99 , pp. 2505-2511
    • Kostense, S.1
  • 2
    • 0037122796 scopus 로고    scopus 로고
    • Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
    • Barouch, D.H. et al. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415, 335-339 (2002).
    • (2002) Nature , vol.415 , pp. 335-339
    • Barouch, D.H.1
  • 3
    • 0035885920 scopus 로고    scopus 로고
    • Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection
    • Lieberman, J., Shankar, P., Manjunath, N. & Andersson, J. Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood 98, 1667-1677 (2001).
    • (2001) Blood , vol.98 , pp. 1667-1677
    • Lieberman, J.1    Shankar, P.2    Manjunath, N.3    Andersson, J.4
  • 4
    • 0035282444 scopus 로고    scopus 로고
    • Skewed maturation of memory HIV-specific CD8 T lymphocytes
    • Champagne, P. et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 410, 106-111 (2001).
    • (2001) Nature , vol.410 , pp. 106-111
    • Champagne, P.1
  • 5
    • 0030726383 scopus 로고    scopus 로고
    • Host factors in the pathogenesis of HIV disease
    • Cohen, O.J., Kinter, A. & Fauci, A.S. Host factors in the pathogenesis of HIV disease. Immunol. Rev. 159, 31-48 (1997).
    • (1997) Immunol. Rev. , vol.159 , pp. 31-48
    • Cohen, O.J.1    Kinter, A.2    Fauci, A.S.3
  • 6
    • 0030175971 scopus 로고    scopus 로고
    • Broad cross-neutralizing activity in serum is associated with slow progression and low risk of transmission in primate lentivirus infections
    • Fenyo, E.M. & Putkonen, P. Broad cross-neutralizing activity in serum is associated with slow progression and low risk of transmission in primate lentivirus infections. Immunol. Lett. 51, 95-99 (1996).
    • (1996) Immunol. Lett. , vol.51 , pp. 95-99
    • Fenyo, E.M.1    Putkonen, P.2
  • 8
    • 0031694872 scopus 로고    scopus 로고
    • Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
    • Rossio, J.L. et al. Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins. J. Virol. 72, 7992-8001 (1998).
    • (1998) J. Virol. , vol.72 , pp. 7992-8001
    • Rossio, J.L.1
  • 9
    • 0035106473 scopus 로고    scopus 로고
    • MHC-I-restricted presentation of HIV-1 virion antigens without viral replication
    • Buseyne, F. et al. MHC-I-restricted presentation of HIV-1 virion antigens without viral replication. Nature Med. 7, 344-349 (2001).
    • (2001) Nature Med. , vol.7 , pp. 344-349
    • Buseyne, F.1
  • 10
    • 0036469216 scopus 로고    scopus 로고
    • Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses
    • Mehlhop, E. et al. Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses. J. Immunol. Methods 260, 219-234 (2002).
    • (2002) J. Immunol. Methods , vol.260 , pp. 219-234
    • Mehlhop, E.1
  • 11
    • 0033011902 scopus 로고    scopus 로고
    • Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses
    • Sapp, M. et al. Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses. Immunol. Lett. 66, 121-128 (1999).
    • (1999) Immunol. Lett. , vol.66 , pp. 121-128
    • Sapp, M.1
  • 12
    • 0033179535 scopus 로고    scopus 로고
    • Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: Implications for immunotherapy
    • Chougnet, C. et al. Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: implications for immunotherapy. J. Immunol. 163, 1666-1673 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 1666-1673
    • Chougnet, C.1
  • 13
    • 0035451366 scopus 로고    scopus 로고
    • Enhanced dendritic-cells-driven proliferation and anti-HIV activity of CD8+ T cells by a new phenothiazine derivative aminoperazine
    • Lu, W., Achour, A., Arlie, M., Cao, L. & Andrieu, J.M. Enhanced dendritic-cells-driven proliferation and anti-HIV activity of CD8+ T cells by a new phenothiazine derivative aminoperazine. J. Immunol. 167, 2929-2935 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 2929-2935
    • Lu, W.1    Achour, A.2    Arlie, M.3    Cao, L.4    Andrieu, J.M.5
  • 14
    • 0034858032 scopus 로고    scopus 로고
    • In vitro HIV eradication by autologous CD8+ T cells expanded with inactivated-virus-pulsed dendritic cells
    • Lu, W. & Andrieu, J.M. In vitro HIV eradication by autologous CD8+ T cells expanded with inactivated-virus-pulsed dendritic cells. J. Virol. 75, 8949-8956 (2001).
    • (2001) J. Virol. , vol.75 , pp. 8949-8956
    • Lu, W.1    Andrieu, J.M.2
  • 15
    • 0034564472 scopus 로고    scopus 로고
    • Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention
    • Hirsch, V.M. & Lifson, J.D. Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention. Adv. Pharmacol. 49, 437-477 (2000).
    • (2000) Adv. Pharmacol. , vol.49 , pp. 437-477
    • Hirsch, V.M.1    Lifson, J.D.2
  • 16
    • 0032822698 scopus 로고    scopus 로고
    • Equivalent amplification of intrinsically variable nucleic acid sequences by multiple-primer-induced overlapping amplification assay: Applications for universal detection and quantitation
    • Lu, W., Cao, L., Ty, L., Arlie, M. & Andrieu, J.M. Equivalent amplification of intrinsically variable nucleic acid sequences by multiple-primer-induced overlapping amplification assay: applications for universal detection and quantitation. Nature Med. 5, 1081-1085 (1999).
    • (1999) Nature Med. , vol.5 , pp. 1081-1085
    • Lu, W.1    Cao, L.2    Ty, L.3    Arlie, M.4    Andrieu, J.M.5
  • 17
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • Nair, S.K. et al. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nature Biotechnol. 16, 364-369 (1998).
    • (1998) Nature Biotechnol. , vol.16 , pp. 364-369
    • Nair, S.K.1
  • 18
    • 0343953009 scopus 로고    scopus 로고
    • Quantitative analysis of the antiviral activity of CD8(+) T cells from human immunodeficiency virus-positive asymptomatic patients with different rates of CD4(+) T-cell decrease
    • Salerno-Goncalves, R., Lu, W. & Andrieu, J.M. Quantitative analysis of the antiviral activity of CD8(+) T cells from human immunodeficiency virus-positive asymptomatic patients with different rates of CD4(+) T-cell decrease. J. Virol. 74, 6648-6651 (2000).
    • (2000) J. Virol. , vol.74 , pp. 6648-6651
    • Salerno-Goncalves, R.1    Lu, W.2    Andrieu, J.M.3
  • 19
    • 0029008769 scopus 로고
    • Prospective views of HIV pathology. Clues for therapeutic strategies
    • Lu, W. & Andrieu, J.M. Prospective views of HIV pathology. Clues for therapeutic strategies. Adv. Exp. Med. Biol. 374, 235-242 (1995).
    • (1995) Adv. Exp. Med. Biol. , vol.374 , pp. 235-242
    • Lu, W.1    Andrieu, J.M.2
  • 20
    • 0028795278 scopus 로고
    • Viro-immunopathogenesis of HIV disease: Implications for therapy
    • Andrieu, J.M. & Lu, W. Viro-immunopathogenesis of HIV disease: implications for therapy. Immunol. Today 16, 5-7 (1995).
    • (1995) Immunol. Today , vol.16 , pp. 5-7
    • Andrieu, J.M.1    Lu, W.2
  • 21
    • 0034653828 scopus 로고    scopus 로고
    • CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity
    • Hermans, I.F., Ritchie, D.S., Yang, J., Roberts, J.M. & Ronchese, F. CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity. J. Immunol. 164, 3095-3101 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 3095-3101
    • Hermans, I.F.1    Ritchie, D.S.2    Yang, J.3    Roberts, J.M.4    Ronchese, F.5
  • 22
    • 0036200852 scopus 로고    scopus 로고
    • Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo
    • Norbury, C.C., Malide, D., Gibbs, J.S., Bennink, J.R. & Yewdell, J.W. Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo. Nature Immunol. 3, 265-271 (2002).
    • (2002) Nature Immunol. , vol.3 , pp. 265-271
    • Norbury, C.C.1    Malide, D.2    Gibbs, J.S.3    Bennink, J.R.4    Yewdell, J.W.5
  • 23
    • 0032502698 scopus 로고    scopus 로고
    • Low CD83, but normal MHC class II and costimulatory molecule expression, on spleen dendritic cells from HIV+ patients
    • McIlroy, D. et al. Low CD83, but normal MHC class II and costimulatory molecule expression, on spleen dendritic cells from HIV+ patients. AIDS Res. Hum. Retroviruses 14, 505-513 (1998).
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 505-513
    • McIlroy, D.1
  • 24
    • 0037089418 scopus 로고    scopus 로고
    • Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS
    • Zimmer, M.I. et al. Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS. Blood 99, 2859-2868 (2002).
    • (2002) Blood , vol.99 , pp. 2859-2868
    • Zimmer, M.I.1
  • 25
    • 0033567061 scopus 로고    scopus 로고
    • Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells
    • Ludewig, B. et al. Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells. J. Immunol. 163, 1839-1844 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 1839-1844
    • Ludewig, B.1
  • 26
    • 0034279805 scopus 로고    scopus 로고
    • An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes
    • Jin, X. et al. An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes. Mol. Med. 6, 803-809 (2000).
    • (2000) Mol. Med. , vol.6 , pp. 803-809
    • Jin, X.1
  • 27
    • 0032789091 scopus 로고    scopus 로고
    • Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy
    • Kalams, S.A. et al. Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy. J. Virol. 73, 6721-6728 (1999).
    • (1999) J. Virol. , vol.73 , pp. 6721-6728
    • Kalams, S.A.1
  • 28
    • 0033083859 scopus 로고    scopus 로고
    • Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART)
    • Gray, C.M. et al. Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART). J. Immunol. 162, 1780-1788 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 1780-1788
    • Gray, C.M.1
  • 29
    • 0035892117 scopus 로고    scopus 로고
    • Reduced blood CD123+ (lymphoid) and CD11 c+ (myeloid) dendritic cell numbers in primary HIV-1 infection
    • Pacanowski, J. et al. Reduced blood CD123+ (lymphoid) and CD11 c+ (myeloid) dendritic cell numbers in primary HIV-1 infection. Blood 98, 3016-3021 (2001).
    • (2001) Blood , vol.98 , pp. 3016-3021
    • Pacanowski, J.1
  • 30
    • 0035178909 scopus 로고    scopus 로고
    • Decreased interferon-α production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors
    • Feldman, S. et al. Decreased interferon-α production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors. Clin. Immunol. 101, 201-210 (2001).
    • (2001) Clin. Immunol. , vol.101 , pp. 201-210
    • Feldman, S.1
  • 31
    • 0035889156 scopus 로고    scopus 로고
    • Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load
    • Donaghy, H. et al. Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load. Blood 98, 2574-2576 (2001).
    • (2001) Blood , vol.98 , pp. 2574-2576
    • Donaghy, H.1
  • 32
    • 0032950671 scopus 로고    scopus 로고
    • Depletion in blood CD11c-positive dendritic cells from HIV-infected patients
    • Grassi, F. et al. Depletion in blood CD11c-positive dendritic cells from HIV-infected patients. Aids 13, 759-766 (1999).
    • (1999) Aids , vol.13 , pp. 759-766
    • Grassi, F.1
  • 33
    • 0034687071 scopus 로고    scopus 로고
    • Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy
    • Grabar, S. et al. Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann. Intern. Med. 133, 401-410 (2000).
    • (2000) Ann. Intern. Med. , vol.133 , pp. 401-410
    • Grabar, S.1
  • 34
    • 0034641205 scopus 로고    scopus 로고
    • Immune restoration with antiretroviral therapies: Implications for clinical management
    • Lederman, M.M. & Valdez, H. Immune restoration with antiretroviral therapies: implications for clinical management. JAMA 284, 223-228 (2000).
    • (2000) JAMA , vol.284 , pp. 223-228
    • Lederman, M.M.1    Valdez, H.2
  • 35
    • 0000228695 scopus 로고    scopus 로고
    • Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression
    • Hatano, H. et al. Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression. Aids 14, 1357-1363 (2000).
    • (2000) Aids , vol.14 , pp. 1357-1363
    • Hatano, H.1
  • 36
    • 0033592967 scopus 로고    scopus 로고
    • HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
    • Davey, R.T. Jr. et al. HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression. Proc. Natl. Acad. Sci. USA 96, 15109-15114 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 15109-15114
    • Davey R.T., Jr.1
  • 37
    • 0034235402 scopus 로고    scopus 로고
    • HIV protease inhibitors restore impaired T-cell proliferative response in vivo and in vitro: A viral-suppression-independent mechanism
    • Lu, W. & Andrieu, J.M. HIV protease inhibitors restore impaired T-cell proliferative response in vivo and in vitro: a viral-suppression-independent mechanism. Blood 96, 250-258 (2000).
    • (2000) Blood , vol.96 , pp. 250-258
    • Lu, W.1    Andrieu, J.M.2


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