메뉴 건너뛰기




Volumn 96, Issue 1, 2000, Pages 250-258

HIV protease inhibitors restore impaired T-cell proliferative response in vivo and in vitro: A viral-suppression-independent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; BETA 2 MICROGLOBULIN; CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; INDINAVIR; LAMIVUDINE; NUCLEOSIDE ANALOG; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

EID: 0034235402     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.1.250.013k28_250_258     Document Type: Article
Times cited : (66)

References (34)
  • 1
    • 2442723342 scopus 로고    scopus 로고
    • Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine
    • Collier AC, Coombs RW, Schoenfeld DA, et al. Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. N Engl J Med. 1996;334:1011-1017.
    • (1996) N Engl J Med , vol.334 , pp. 1011-1017
    • Collier, A.C.1    Coombs, R.W.2    Schoenfeld, D.A.3
  • 2
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in patients with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    • Hammer SM, Squires KE, Hugher MD, et al. A controlled trial of two nucleoside analogues plus indinavir in patients with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med. 1997; 337:725-733.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hugher, M.D.3
  • 3
    • 15144342918 scopus 로고    scopus 로고
    • Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
    • Cavert W, Notermans DW, Staskus K, et al. Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science. 1997; 276:960-964.
    • (1997) Science , vol.276 , pp. 960-964
    • Cavert, W.1    Notermans, D.W.2    Staskus, K.3
  • 4
    • 0032490305 scopus 로고    scopus 로고
    • Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease
    • Li TS, Tubiana R, Katlama C, Calvez V, Mohand HA, Autran B. Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease. Lancet. 1998;351:1682-1686.
    • (1998) Lancet , vol.351 , pp. 1682-1686
    • Li, T.S.1    Tubiana, R.2    Katlama, C.3    Calvez, V.4    Mohand, H.A.5    Autran, B.6
  • 5
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • Palella FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med. 1998;338:853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 6
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME, et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature. 1995,373:117-122.
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 8
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation
    • Pakker NG, Notermans DW, de Boer RJ, et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nat Med. 1998;4:208-214.
    • (1998) Nat Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    De Boer, R.J.3
  • 9
    • 0031873665 scopus 로고    scopus 로고
    • + T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy
    • + T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy. Nat Med. 1998;4:794-801.
    • (1998) Nat Med , vol.4 , pp. 794-801
    • Fleury, S.1    De Boer, R.J.2    Rizzardi, G.P.3
  • 10
    • 0032492398 scopus 로고    scopus 로고
    • CD4-cell count in HIV-1-infected individuals remaining viraemic with Highly Active Antiretroviral Therapy (HAART): Swiss HIV Cohort Study
    • Kaufmann D, Pantaleo G, Sudre P, Telenti A. CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART): Swiss HIV Cohort Study. Lancet. 1998;351:723-724.
    • (1998) Lancet , vol.351 , pp. 723-724
    • Kaufmann, D.1    Pantaleo, G.2    Sudre, P.3    Telenti, A.4
  • 11
    • 0032499143 scopus 로고    scopus 로고
    • + cell counts despite persistently detectable HIV load
    • + cell counts despite persistently detectable HIV load. N Engl J Med. 1998;338:1074-1075.
    • (1998) N Engl J Med , vol.338 , pp. 1074-1075
    • Levetz, S.M.1
  • 12
    • 0032548547 scopus 로고    scopus 로고
    • AIDS therapy: Failure isn't what it used to be . . .but neither is success
    • Cohen J. AIDS therapy: failure isn't what it used to be . . .but neither is success. Science. 1998; 279:1133-1134.
    • (1998) Science , vol.279 , pp. 1133-1134
    • Cohen, J.1
  • 13
    • 0032900581 scopus 로고    scopus 로고
    • Stable plasma levels of cytokines and soluble activation markers in patients with immunodeficiency virus infection
    • Aziz N, Nishanian P, Taylor JM, et al. Stable plasma levels of cytokines and soluble activation markers in patients with immunodeficiency virus infection. J Infect Dis. 1999;179:843-848.
    • (1999) J Infect Dis , vol.179 , pp. 843-848
    • Aziz, N.1    Nishanian, P.2    Taylor, J.M.3
  • 14
    • 0025069873 scopus 로고
    • The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1
    • Fahey JL, Tayler JM, Detels R, el al. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med. 1990;322;166-172.
    • (1990) N Engl J Med , vol.322 , pp. 166-172
    • Fahey, J.L.1    Tayler, J.M.2    Detels, R.3    El, A.4
  • 15
    • 0026762698 scopus 로고
    • 2-microglobulin and prediction of progression to AIDS in HIV infection
    • 2-microglobulin and prediction of progression to AIDS in HIV infection. Lancet. 1992;339: 1436-1440.
    • (1992) Lancet , vol.339 , pp. 1436-1440
    • Lifson, A.R.1    Hesso, N.A.2    Buchbinder, S.P.3
  • 16
    • 0028795278 scopus 로고
    • Viro-immunopathogenesis of HIV disease: Implications for therapy
    • Andrieu JM, Lu W. Viro-immunopathogenesis of HIV disease: implications for therapy. Immunol Today. 1995;16:5-7.
    • (1995) Immunol Today , vol.16 , pp. 5-7
    • Andrieu, J.M.1    Lu, W.2
  • 17
    • 0028889950 scopus 로고
    • + T lymphocytes from activation-induced apoptosis triggered by HIV-1 : Implication for pathogenesis and therapy
    • + T lymphocytes from activation-induced apoptosis triggered by HIV-1 : implication for pathogenesis and therapy. AIDS. 1995;9:35-42.
    • (1995) AIDS , vol.9 , pp. 35-42
    • Lu, W.1    Salerno-Goncalves, R.2    Yuan, J.3    Sylvie, D.4    Han, D.S.5    Andrieu, J.M.6
  • 18
    • 0028916825 scopus 로고
    • Sustained increases in CD4 cell counts in asymptomatic human immunodeficiency virus type 1-seropositive patients treated with prednisolone for 1 year
    • Andrieu JM, Lu W, Levy R. Sustained increases in CD4 cell counts in asymptomatic human immunodeficiency virus type 1-seropositive patients treated with prednisolone for 1 year. J Infect Dis. 1995;171:523-530.
    • (1995) J Infect Dis , vol.171 , pp. 523-530
    • Andrieu, J.M.1    Lu, W.2    Levy, R.3
  • 19
    • 0031753527 scopus 로고    scopus 로고
    • Resistance mutations in protease and reverse transcriptase genes of human immunodeficiency virus type 1 isolates from patients with combination antiretroviral therapy failure
    • Young B, Johnson S, Bahktiari M, et al. Resistance mutations in protease and reverse transcriptase genes of human immunodeficiency virus type 1 isolates from patients with combination antiretroviral therapy failure. J Infect Dis. 1998; 178:1497-1501.
    • (1998) J Infect Dis , vol.178 , pp. 1497-1501
    • Young, B.1    Johnson, S.2    Bahktiari, M.3
  • 20
    • 0030792728 scopus 로고    scopus 로고
    • Toxicity, efficacy, plasma drug concentrations and protease mutations in patients with advanced HIV infection treated with ritonavir plus saquinavir
    • Lorenzi PL, Yerly S, Abderrakim K, et al. Toxicity, efficacy, plasma drug concentrations and protease mutations in patients with advanced HIV infection treated with ritonavir plus saquinavir. AIDS. 1997;11:F95-F99.
    • (1997) AIDS , vol.11
    • Lorenzi, P.L.1    Yerly, S.2    Abderrakim, K.3
  • 21
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlations of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
    • Condra JH, Holder DJ, Schleif WA, et al. Genetic correlations of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol. 1996;70:8270-8276.
    • (1996) J Virol , vol.70 , pp. 8270-8276
    • Condra, J.H.1    Holder, D.J.2    Schleif, W.A.3
  • 22
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutation in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, et al. Ordered accumulation of mutation in HIV protease confers resistance to ritonavir. Nat Med. 1996;2:760-766.
    • (1996) Nat Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3
  • 25
    • 0025455456 scopus 로고
    • Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus infected men
    • Van Noesel CJ, Gruter RA, Terpstra FA, Schelledens PT, Van Lier RA, Miedema F. Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus infected men. J Clin Invest 1990; 86:293-299.
    • (1990) J Clin Invest , vol.86 , pp. 293-299
    • Van Noesel, C.J.1    Gruter, R.A.2    Terpstra, F.A.3    Schelledens, P.T.4    Van Lier, R.A.5    Miedema, F.6
  • 26
    • 0031041479 scopus 로고    scopus 로고
    • Relation of impaired lymphocyte proliferative function to other major human immunodeficiency virus type 1-induced immunological changes
    • Bass HZ, Fahey JL, Nishanian P, et al. Relation of impaired lymphocyte proliferative function to other major human immunodeficiency virus type 1-induced immunological changes. Clin Diagn Lab Immunol. 1997;4:64-69.
    • (1997) Clin Diagn Lab Immunol , vol.4 , pp. 64-69
    • Bass, H.Z.1    Fahey, J.L.2    Nishanian, P.3
  • 27
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature. 1993;362:355-358.
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3
  • 28
    • 0027516822 scopus 로고
    • Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
    • Embretson J, Zupancic M, Ribas JL, et al. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature. 1993;362:359-362.
    • (1993) Nature , vol.362 , pp. 359-362
    • Embretson, J.1    Zupancic, M.2    Ribas, J.L.3
  • 29
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV-infected lymph nodes
    • Finkel TH, Tudor-Williams G, Banda NK, et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV-infected lymph nodes. Nat Med. 1995;1: 129-134.
    • (1995) Nat Med , vol.1 , pp. 129-134
    • Finkel, T.H.1    Tudor-Williams, G.2    Banda, N.K.3
  • 30
    • 84993888631 scopus 로고
    • Apoptosis and HIV disease
    • Lu W, Andrieu JM. Apoptosis and HIV disease. Nat Med. 1995;1:386-387.
    • (1995) Nat Med , vol.1 , pp. 386-387
    • Lu, W.1    Andrieu, J.M.2
  • 31
    • 0033550965 scopus 로고    scopus 로고
    • Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: A prospective cohort study
    • Ledergerber B, Egger M, Opravil M, et al. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Lancet. 1999;353:863-868.
    • (1999) Lancet , vol.353 , pp. 863-868
    • Ledergerber, B.1    Egger, M.2    Opravil, M.3
  • 33
    • 3042799131 scopus 로고    scopus 로고
    • Early effects of antiretroviral combination therapy on activation, apoptosis and regeneration of T cells in HIV-1-infected children and adolescents
    • Bohler T, Walcher J, Golzl-Wening G, et al. Early effects of antiretroviral combination therapy on activation, apoptosis and regeneration of T cells in HIV-1-infected children and adolescents. AIDS. 1999;13:779-789.
    • (1999) AIDS , vol.13 , pp. 779-789
    • Bohler, T.1    Walcher, J.2    Golzl-Wening, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.