Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS

Blood

Volumn 99, Issue 8, 2002, Pages 2859-2868

  Zimmer, Michael I ^a,b   Larregina, Adriana T ^a,b   Castillo, Cielo M ^a,b   Capuano III, Saverio ^a,b   Falo Jr , Louis D ^a,b   Murphey Corb, Michael ^a,b   Reinhart, Todd A ^a,b   Barratt Boyes, Simon M ^a,b  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD83 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DENDRITIC CELL; DISEASE COURSE; FEMALE; FLOW CYTOMETRY; HOMEOSTASIS; IMMUNOPATHOLOGY; LANGERHANS CELL; LYMPH NODE; MALE; MONKEY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0037089418     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.8.2859     Document Type: Article

References (59)

1. Immunobiology of dendritic cells
2. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites
3. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
4. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells
5. Cutting edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
6. Human interdigitating dendritic cells directly stimulate CD40-activated naive B cells
7. Phenotypic characterization of five dendritic cell subsets in human tonsils
8. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques
9. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells
10. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV -1
11. Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia
12. Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid
13. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
14. Dendritic cell infection, depletion and dysfunction in HIV-infected individuals
15. Depletion in blood CD11 c-positive dendritic cells from HIV-infected patients
16. Comparative loss and maturation of peripheral blood dendritic cell subpopulations in African and non-African HIV-1-infected patients
17. Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients
18. - T cell demographics and dynamics in lymphatic tissues
19. Low CD83, but normal MHC class II and costimulatory molecule expression, on spleen dendritic cells from HIV+ patients
20. Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons
21. Modulation of T cell responses to recall antigens presented by Langerhans cells in HIV-discordant identical twins by anti-interleukin (IL)-10 antibodies and IL-12
22. Does HIV disease progression influence epidermal Langerhans cell density?
23. Retrovirus-induced immunosuppression via blocking of dendritic cell migration and down-regulation of adhesion molecules
24. Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys
25. Flow cytometric analysis of cytokine receptors on human Langerhans' cells. Changes observed after short-term culture
26. Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies
27. Direct transfection and activation of human cutaneous dendritic cells
28. Maturation and trafficking of monocyte-derived dendritic cells in monkeys: Implications for dendritic cell-based vaccines
29. Improved detection of simian immunodeficiency virus RNA by in situ hybridization in fixed tissue sections: Combined effects of temperatures for tissue fixation and probe hybridization
30. In vivo migration of dendritic cells differentiated in vitro: A chimpanzee model
31. A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily
32. Circulating human dendritic cells differentially express high levels of a 55-kd actin-bundling protein
33. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses
34. Fascin is involved in the antigen presentation activity of mature dendritic cells
35. Immunophenotypic characterization of simian immunodeficiency virus-infected dendritic cells in cervix, vagina, and draining lymph nodes of rhesus monkeys
36. Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection
37. Macrophage-tropic HIV induces and exploits dendritic cell chemotaxis
38. Immunohistochemical study of normal skin of HIV-1-infected patients shows no evidence of infection of epidermal Langerhans cells by HIV
39. Epidermal Langerhans cells are not principal reservoirs of virus in HIV disease
40. - T cells
41. Inhibition of dendritic cell maturation by herpes simplex virus
42. Trypanosoma cruzi infects human dendritic cells and prevents their maturation: Inhibition of cytokines, HLA-DR, and costimulatory molecules
43. Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways
44. Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells
45. - T lymphocytes in spleens of human immunodeficiency virus-positive patients
46. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells
47. Mechanism of measles virus-induced suppression of inflammatory immune responses
48. Role of IL12 in HIV disease/AIDS
49. HIV-induced immunopathogenesis
50. Induction of tolerance by IL-10-treated dendritic cells
51. Macaques with rapid disease progression and simian immunodeficiency virus encephalitis have a unique cytokine profile in peripheral lymphoid tissues
52. Enhanced epidermal Langerhans cell migration in IL-10 knockout mice
53. Help for cytotoxic-T-ce responses is mediated by CD40 signaling
54. - T-helper and a T-killer cell
55. T-cell help for cytotoxic T lyrr phocytes is mediated by CD40-CD40L interactions
56. DNA-based immunization by in vivo transfection of dendritic cells
57. Induc tion of mucosal protection against primary, heter ologous SIV by a DNA vaccine
58. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
59. Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection