-
1
-
-
0023735981
-
Epidemiology and the prevention of cancer: some recent developments
-
Doll R. Epidemiology and the prevention of cancer: some recent developments. J Cancer Res Clin Oncol 1988 ; 114: 447-58.
-
(1988)
J Cancer Res Clin Oncol
, vol.114
, pp. 447-458
-
-
Doll, R.1
-
2
-
-
0027333079
-
Groopman J. Diet and carcinogenesis
-
Rogers AE, Zeisel SH, and Groopman J. Diet and carcinogenesis. Carcinogenesis 1993; 14: 2205-17.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2205-2217
-
-
Rogers, A.E.1
Zeisel, S.H.2
-
3
-
-
0028596157
-
A need to reinvent biotechnology regulation at the EPA
-
Miller HI. A need to reinvent biotechnology regulation at the EPA. Science 1994 ; 266 : 1815-18.
-
(1994)
Science
, vol.266
, pp. 1815-1818
-
-
Miller, H.I.1
-
5
-
-
0023158058
-
Carcinogenicity of mutagens : Predictive capability of the Salmonella mutagenesis assay for rodent carcinogenicity
-
Zeiger E. Carcinogenicity of mutagens : Predictive capability of the Salmonella mutagenesis assay for rodent carcinogenicity. Cancer Res 1987 ; 47 : 1287-96.
-
(1987)
Cancer Res
, vol.47
, pp. 1287-1296
-
-
Zeiger, E.1
-
6
-
-
0023855146
-
A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures
-
Ishidate M Jr, Harnois MC, and Sofuni T. A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures. Mutat Res 1988 195: 151-213.
-
(1988)
Mutat Res
, vol.195
, pp. 151-213
-
-
Ishidate, M.1
Harnois, M.C.2
Sofuni, T.3
-
7
-
-
85024735632
-
Definitive relationship among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U. S. NTP
-
Ashby J and Tennant RW. Definitive relationship among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U. S. NTP. Mutat Res 1991 257229-306.
-
(1991)
Mutat Res
, pp. 257229-257306
-
-
Ashby, J.1
-
8
-
-
0023752610
-
Development of new medium-term bioassays for carcinogens
-
Ward JM and Ito N. Development of new medium-term bioassays for carcinogens. Cancer Res 1988 ; 48 : 5051-54.
-
(1988)
Cancer Res
, vol.48
, pp. 5051-5054
-
-
Ward, J.M.1
-
9
-
-
0015142880
-
Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene
-
Peraino C, Fry RJM, and Staffeldt E. Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene. Cancer Res 1971 31 1506-12.
-
(1971)
Cancer Res
, pp. 1506-1512
-
-
Peraino, C.1
Fry, R.J.M.2
Staffeldt, E.3
-
10
-
-
0021669403
-
Comparison of different models of rat liver carcinogenesis: conclusions from a systemic analysis
-
de Gerlache J, Lans M, Preat V, Taper H, and Roberfroid M. Comparison of different models of rat liver carcinogenesis: conclusions from a systemic analysis. Toxicol Pathol 1984; 12: 374-82.
-
(1984)
Toxicol Pathol
, vol.12
, pp. 374-382
-
-
de Gerlache, J.1
Lans, M.2
Preat, V.3
Taper, H.4
Roberfroid, M.5
-
11
-
-
77957185391
-
An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenicity bioassay
-
Dragan YP, Rizvi T, Xu YH, Hully JR, Bawa N, Campbell HA, Maronpot RR, and Pitot H. An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenicity bioassay. Fund Appl Toxicol 1991; 16: 525-47.
-
(1991)
Fund Appl Toxicol
, vol.16
, pp. 525-547
-
-
Dragan, Y.P.1
Rizvi, T.2
Xu, Y.H.3
Hully, J.R.4
Bawa, N.5
Campbell, H.A.6
Maronpot, R.R.7
Pitot, H.8
-
12
-
-
0017166164
-
New principle for the analysis of chemical carcinogenesis
-
Solt D and Farber E. New principle for the analysis of chemical carcinogenesis. Nature 1976; 263 : 701-3.
-
(1976)
Nature
, vol.263
, pp. 701-703
-
-
Solt, D.1
-
13
-
-
0020554928
-
Assay of some endogenous and synthetic sex steroids for tumor-initiation activity in rat liver using the Solt-Farber system
-
Schuppler J, Damme J, and Schulte-Hermann R. Assay of some endogenous and synthetic sex steroids for tumor-initiation activity in rat liver using the Solt-Farber system. Carcinogenesis 1983; 4 : 239-41.
-
(1983)
Carcinogenesis
, vol.4
, pp. 239-241
-
-
Schuppler, J.1
Damme, J.2
Schulte-Hermann, R.3
-
14
-
-
0023020296
-
Preneoplastic lesions as end points in carcinogenicity testing
-
Bannasch P. Preneoplastic lesions as end points in carcinogenicity testing. I. Hepatic neoplasia. Carcinogenesis 1986 ; 7: 689-95.
-
(1986)
I. Hepatic neoplasia. Carcinogenesis
, vol.7
, pp. 689-695
-
-
Bannasch, P.1
-
15
-
-
85024747098
-
Detection of chemical carcinogens by means of the rat liver bioassay
-
Oesterle D and Demi E. Detection of chemical carcinogens by means of the rat liver bioassay. Exp Pathol 1990; 39: 197206.
-
(1990)
Exp Pathol
, vol.39
, pp. 197206
-
-
Oesterle, D.1
-
16
-
-
0024364295
-
Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis
-
Ito N, Imaida K, Hasegawa R, and Tsuda H. Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis. CRC Crit Rev Toxicol 1989; 19: 385-415.
-
(1989)
CRC Crit Rev Toxicol
, vol.19
, pp. 385-415
-
-
Ito, N.1
Imaida, K.2
Hasegawa, R.3
Tsuda, H.4
-
17
-
-
0026497121
-
Medium-term bioassay for carcinogens
-
Ito N, Shirai T, and Hasegawa R. Medium-term bioassay for carcinogens. In: Mechanisms of Carcinogenesis in Risk Assessment, H Vainio, PN Magee, DB McGregor, AJ McMichael Eds, IARC Scientific Publications, No. 116, Lyon: IARC, 345-80, 1992.
-
(1992)
IARC Scientific Publications
, vol.345
-
-
Ito, N.1
Shirai, T.2
Hasegawa, R.3
-
18
-
-
0019254038
-
The effects of various chemicals on the development of hyperplastic liver nodules in hepatectom-ized rats treated with N-nitrosodiethylamine or N-2-fluorenylacetamide
-
Ito N, Tatematsu M, Nakanishi K, Hasegawa R, Takano T, Imaida K, and Ogiso T. The effects of various chemicals on the development of hyperplastic liver nodules in hepatectom-ized rats treated with N-nitrosodiethylamine or N-2-fluorenylacetamide. Gann 1980 ; 71: 832-42.
-
(1980)
Gann
, vol.71
, pp. 832-842
-
-
Ito, N.1
Tatematsu, M.2
Nakanishi, K.3
Hasegawa, R.4
Takano, T.5
Imaida, K.6
Ogiso, T.7
-
19
-
-
0019843755
-
Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis
-
Imaida K, Shirai T, Tatematsu M, Takano T, and Ito N. Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis. Cancer Lett 1981; 14: 279-83.
-
(1981)
Cancer Lett
, vol.14
, pp. 279-283
-
-
Imaida, K.1
Shirai, T.2
Tatematsu, M.3
Takano, T.4
Ito, N.5
-
20
-
-
0021843339
-
Different responses to phenobarbital promotion in the development of y-glutamyl tranpeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetylaminofluorene and aflatoxin B
-
Shirai T, Imaida K, Ohshima M, Fukushima S, Lee M-S, King MC, and Ito N. Different responses to phenobarbital promotion in the development of y-glutamyl tranpeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetylaminofluorene and aflatoxin B,. Jpn J Cancer Res (Gann) 1985; 76: 16-19. 22. Shirai T, Masuda A, Imaida K, Ogiso T, and Ito N. Effects of phenobarbital and carbazole on carcinogenesis of the lung, thyroid, kidney, and bladder of rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. Jpn J Cancer Res (Gann) 1988 ; 79 : 460-65.
-
(1985)
Jpn J Cancer Res (Gann)
, vol.1988
, pp. 16-19
-
-
Shirai, T.1
Imaida, K.2
Ohshima, M.3
Fukushima, S.4
Lee, M-S.5
King, M.C.6
Ito, N.7
-
21
-
-
0019863469
-
Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethyl-nitrosamine orally
-
Hirose M, Shirai T, Tsuda H, Fukushima S, Ogiso T, and Ito N. Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethyl-nitrosamine orally. Carcinogenesis 1981 ; 2: 1299-302.
-
(1981)
Carcinogenesis
, vol.2
, pp. 1299-1302
-
-
Hirose, M.1
Shirai, T.2
Tsuda, H.3
Fukushima, S.4
Ogiso, T.5
Ito, N.6
-
22
-
-
0019154463
-
Effects of various promoters on the induction of hyperplastic nodules in rat liver
-
Ito N, Tatematsu M, Imaida K, Hasegawa R, and Murasaki G. Effects of various promoters on the induction of hyperplastic nodules in rat liver. Gann 1980; 71: 415-16.
-
(1980)
Gann
, vol.71
, pp. 415-416
-
-
Ito, N.1
Tatematsu, M.2
Imaida, K.3
Hasegawa, R.4
Murasaki, G.5
-
23
-
-
0020964668
-
Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats
-
Tatematsu M, Hasegawa R, Imaida K, Tsuda H, and Ito N. Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats. Carcinogenesis 1983; 4: 381-86.
-
(1983)
Carcinogenesis
, vol.4
, pp. 381-386
-
-
Tatematsu, M.1
Hasegawa, R.2
Imaida, K.3
Tsuda, H.4
Ito, N.5
-
24
-
-
0026356948
-
Dose response study of N-nitrosodiethanolamine for initiation of rat hepatocarcinogenesis
-
Ogawa K, Hasegawa R, Wada S, Yamaguchi S, and Ito N. Dose response study of N-nitrosodiethanolamine for initiation of rat hepatocarcinogenesis. Teratogen Carcinogen Mutagen 1992; 11: 245-50.
-
(1992)
Teratogen Carcinogen Mutagen
, vol.11
, pp. 245-250
-
-
Ogawa, K.1
Hasegawa, R.2
Wada, S.3
Yamaguchi, S.4
Ito, N.5
-
25
-
-
0022225586
-
Promotion effects of phenobarbital and 3ʹ-methyl-4-dimethylaminoazobenzene on the appearance of γ-glutamyl transpeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine
-
Shirai T, Hosoda K, Hirose K, Hirose M, and Ito N. Promotion effects of phenobarbital and 3ʹ-methyl-4-dimethylaminoazobenzene on the appearance of γ-glutamyl transpeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine. Cancer Lett 1985 ; 28 : 127-33.
-
(1985)
Cancer Lett
, vol.28
, pp. 127-133
-
-
Shirai, T.1
Hosoda, K.2
Hirose, K.3
Hirose, M.4
Ito, N.5
-
26
-
-
0022486201
-
Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens
-
Hasegawa R, Tsuda H, Shirai T, Kurata Y, Masuda A, and Ito N. Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. Cancer Lett 1986; 32: 15-23.
-
(1986)
Cancer Lett
, vol.32
, pp. 15-23
-
-
Hasegawa, R.1
Tsuda, H.2
Shirai, T.3
Kurata, Y.4
Masuda, A.5
Ito, N.6
-
27
-
-
0029151624
-
Hepatocyte growth factor enhancement of preneoplastic hepatic foci development in rats treated with diethylnitrosamine and N-ethyl-N-hydroxyethyl-nitrosamine
-
Yaono M, Hasegawa R, Mizoguchi Y, Futakuchi M, Nakamura K, Ito N, and Shirai T. Hepatocyte growth factor enhancement of preneoplastic hepatic foci development in rats treated with diethylnitrosamine and N-ethyl-N-hydroxyethyl-nitrosamine. Jpn J Cancer Res 1995; 86 : 718-23.
-
(1995)
Jpn J Cancer Res
, vol.86
, pp. 718-723
-
-
Yaono, M.1
Hasegawa, R.2
Mizoguchi, Y.3
Futakuchi, M.4
Nakamura, K.5
Ito, N.6
Shirai, T.7
-
28
-
-
0017644142
-
Rapid production of hyperplastic liver nodules in rats treated with carcinogenic chemicals : a new approach for an in vivo short-term screening test for hepatocarcinogens
-
Tatematsu M, Shirai T, Tsuda H, Miyata Y, Shinohara Y, and Ito N. Rapid production of hyperplastic liver nodules in rats treated with carcinogenic chemicals : a new approach for an in vivo short-term screening test for hepatocarcinogens. Gann 1977; 68 : 499-507.
-
(1977)
Gann
, vol.68
, pp. 499-507
-
-
Tatematsu, M.1
Shirai, T.2
Tsuda, H.3
Miyata, Y.4
Shinohara, Y.5
Ito, N.6
-
29
-
-
0018740820
-
Sequential quantitative studies on hyperplastic nodules in the liver of rats treated with carcinogenic chemicals
-
Tatematsu M, Murasaki G, Nakanishi K, Miyata Y, Shinohara Y, and Ito N. Sequential quantitative studies on hyperplastic nodules in the liver of rats treated with carcinogenic chemicals. Gann 1979 ; 70 : 125-30.
-
(1979)
Gann
, vol.70
, pp. 125-130
-
-
Tatematsu, M.1
Murasaki, G.2
Nakanishi, K.3
Miyata, Y.4
Shinohara, Y.5
Ito, N.6
-
30
-
-
0024852384
-
Strain difference in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system
-
Asamoto M, Tsuda H, Kagawa M, de Camargo JLV, Ito N, and Nagase S. Strain difference in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system. Jpn J Cancer Res 1989 ; 80 : 939-44.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 939-944
-
-
Asamoto, M.1
Tsuda, H.2
Kagawa, M.3
de Camargo, J.L.V.4
Ito, N.5
Nagase, S.6
-
31
-
-
0021024831
-
Dose and sex dependent effects of 2-acetylaminofluorene, 3ʹ-methyl-4-dimethylaminoazobenzene and DL-ethionine in induction of y-glutamyl transpeptidase-positive liver cell foci in rats
-
Tamano S, Tsuda H, Fukushima S, Masui T, Hosoda K, and Ito N. Dose and sex dependent effects of 2-acetylaminofluorene, 3ʹ-methyl-4-dimethylaminoazobenzene and DL-ethionine in induction of y-glutamyl transpeptidase-positive liver cell foci in rats. Cancer Lett 1983 ; 20: 313-21.
-
(1983)
Cancer Lett
, vol.20
, pp. 313-321
-
-
Tamano, S.1
Tsuda, H.2
Fukushima, S.3
Masui, T.4
Hosoda, K.5
Ito, N.6
-
32
-
-
0026034157
-
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rat initially treated with diethylnitrosamine
-
Hasegawa R, Takahashi S, Imaida K, Yamaguchi S, Shirai T, and Ito N. Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rat initially treated with diethylnitrosamine. Jpn J Cancer Res 1991; 82 : 293-97.
-
(1991)
Jpn J Cancer Res
, vol.82
, pp. 293-297
-
-
Hasegawa, R.1
Takahashi, S.2
Imaida, K.3
Yamaguchi, S.4
Shirai, T.5
Ito, N.6
-
33
-
-
0021262406
-
The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical carcinogenesis
-
Sato K, Kitahara A, Satoh K, Ichikawa T, Tatematsu M, and Ito N. The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical carcinogenesis. Gann 1984; 75: 199-202.
-
(1984)
Gann
, vol.75
, pp. 199-202
-
-
Sato, K.1
Kitahara, A.2
Satoh, K.3
Ichikawa, T.4
Tatematsu, M.5
Ito, N.6
-
34
-
-
0022179540
-
Relative merits of immunohistochemical demonstration of placental A, B and C forms of glutathione S-transferase and histochemical demonstration of y-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats
-
Tatematsu M, Mera Y, Ito N, Satoh K, and Sato K. Relative merits of immunohistochemical demonstration of placental A, B and C forms of glutathione S-transferase and histochemical demonstration of y-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats. Carcinogenesis 1985; 6: 1621-26.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1621-1626
-
-
Tatematsu, M.1
Mera, Y.2
Ito, N.3
Satoh, K.4
Sato, K.5
-
35
-
-
0023934310
-
Effect of modifying agents on the phenotypic expression of cytochrome P-450, glutathione S-transferase molecular forms, microsomal epoxide hydrolase, glucose-6-phosphate dehydrogenase and y-glutamyltranspeptidase in rat liver preneoplastic lesions
-
Tsuda H, Moore MA, Asamoto M, Inoue T, Ito N, Sato K, Ichihara A, Nakamura T, Amelizad Z, and Oesch F. Effect of modifying agents on the phenotypic expression of cytochrome P-450, glutathione S-transferase molecular forms, microsomal epoxide hydrolase, glucose-6-phosphate dehydrogenase and y-glutamyltranspeptidase in rat liver preneoplastic lesions. Carcinogenesis 1988 ; 9 : 547-54.
-
(1988)
Carcinogenesis
, vol.9
, pp. 547-554
-
-
Tsuda, H.1
Moore, M.A.2
Asamoto, M.3
Inoue, T.4
Ito, N.5
Sato, K.6
Ichihara, A.7
Nakamura, T.8
Amelizad, Z.9
Oesch, F.10
-
36
-
-
0022296627
-
Comparative effects of carcinogens on the induction of placental glutathione S-transferase-positive liver nodules in a short-term assay and of hepatocellular carcinomas in a long-term assay
-
Ogiso T, Tatematsu M, Tamano S, Tsuda H, and Ito N. Comparative effects of carcinogens on the induction of placental glutathione S-transferase-positive liver nodules in a short-term assay and of hepatocellular carcinomas in a long-term assay. Toxicol Pathol 1985 ; 13 : 257-63.
-
(1985)
Toxicol Pathol
, vol.13
, pp. 257-263
-
-
Ogiso, T.1
Tatematsu, M.2
Tamano, S.3
Tsuda, H.4
Ito, N.5
-
37
-
-
0025812038
-
Dose-dependent effects of 2-acetylaminofluorene on hepatic foci development and cell proliferation in rats
-
Tiwawech D, Hasegawa R, Kurata Y, Tatematsu M, Shibata M-A, Thamavit W, and Ito N. Dose-dependent effects of 2-acetylaminofluorene on hepatic foci development and cell proliferation in rats. Carcinogenesis 1991; 12 : 985-90,
-
(1991)
Carcinogenesis
, vol.12
, pp. 985-990
-
-
Tiwawech, D.1
Hasegawa, R.2
Kurata, Y.3
Tatematsu, M.4
Shibata, M-A.5
Thamavit, W.6
Ito, N.7
-
38
-
-
0026795742
-
Dose-dependent formation of preneoplastic foci and DNA adducts in rat liver with 2-amino-3-methyl-9H-pyrido[2, 3-6]indole (MeAarC) and 2-amino-1-methyl-6-phenylimidazo[4, 5-b] pyridine (PhIP)
-
Hasegawa R, Takahashi S, Shirai T, Iwasaki S, Kim D-J, Ochiai M, Nagao M, Sugimura T, and Ito N. Dose-dependent formation of preneoplastic foci and DNA adducts in rat liver with 2-amino-3-methyl-9H-pyrido[2,3-6]indole (MeAarC) and 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP). Carcinogenesis 1992; 13: 1427-31.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1427-1431
-
-
Hasegawa, R.1
Takahashi, S.2
Shirai, T.3
Iwasaki, S.4
Kim, D-J.5
Ochiai, M.6
Nagao, M.7
Sugimura, T.8
Ito, N.9
-
39
-
-
0030062279
-
Medium-term bioassay for the hepatocarcinogenicity of hexachlorobenzene
-
Cabral R, Hoshiya T, Hakoi K, Hasegawa R, and Ito N. Medium-term bioassay for the hepatocarcinogenicity of hexachlorobenzene. Cancer Lett 1996 ; 100: 223-26.
-
(1996)
Cancer Lett
, vol.100
, pp. 223-226
-
-
Cabral, R.1
Hoshiya, T.2
Hakoi, K.3
Hasegawa, R.4
Ito, N.5
-
40
-
-
85024725133
-
Practical applicability of a medium-term liver bioassay system for detection of carcinogens (in Japanese)
-
Hasegawa R, Imaida K, Masui T, Ogawa K, Kato T, and Ito N. Practical applicability of a medium-term liver bioassay system for detection of carcinogens (in Japanese). Jpn J Mutagen Test Chem 1993; 2: 1-10.
-
(1993)
Jpn J Mutagen Test Chem
, vol.2
, pp. 1-10
-
-
Hasegawa, R.1
Imaida, K.2
Masui, T.3
Ogawa, K.4
Kato, T.5
Ito, N.6
-
41
-
-
0028851257
-
Effect of ingestion of 20 pesticides in combination at acceptable daily intake levels on rat liver carcinogenesis
-
Ito N, Hasegawa R, Imaida K, Kurata Y, Hagiwara A, and Shirai T. Effect of ingestion of 20 pesticides in combination at acceptable daily intake levels on rat liver carcinogenesis. Food Chem Toxicol 1995 ; 33 : 159-63.
-
(1995)
Food Chem Toxicol
, vol.33
, pp. 159-163
-
-
Ito, N.1
Hasegawa, R.2
Imaida, K.3
Kurata, Y.4
Hagiwara, A.5
Shirai, T.6
-
42
-
-
0023858438
-
Enhancing effects of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats-an approach for a new medium-term bioassay system
-
Ito N, Tsuda H, Tatematsu M, Inoue T, Tagawa Y, Aoki T, Uwagawa S, Kagawa M, Ogiso T, Masui T, Imaida K, Fukushima S, and Asamoto M. Enhancing effects of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats-an approach for a new medium-term bioassay system. Carcinogenesis 1988 ; 9: 387-94.
-
(1988)
Carcinogenesis
, vol.9
, pp. 387-394
-
-
Ito, N.1
Tsuda, H.2
Tatematsu, M.3
Inoue, T.4
Tagawa, Y.5
Aoki, T.6
Uwagawa, S.7
Kagawa, M.8
Ogiso, T.9
Masui, T.10
Imaida, K.11
Fukushima, S.12
Asamoto, M.13
-
43
-
-
0027062789
-
Liver medium-term bioassay in rats for screening of carcinogens and modifying factors in hepatocarcinogenesis
-
Hasegawa R and Ito N. Liver medium-term bioassay in rats for screening of carcinogens and modifying factors in hepatocarcinogenesis. Food Chem Toxicol 1992 ; 30 : 979-92.
-
(1992)
Food Chem Toxicol
, vol.30
, pp. 979-992
-
-
Hasegawa, R.1
-
44
-
-
0024806442
-
Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction
-
Imaida K, Tatematsu M, Kato T, Tsuda H, and Ito N. Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction. Jpn J Cancer Res 1989 ; 80 : 326-30.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 326-330
-
-
Imaida, K.1
Tatematsu, M.2
Kato, T.3
Tsuda, H.4
Ito, N.5
-
45
-
-
0028058137
-
Lack of promoting activity of 7-methoxy-2-nitro-naphth-o-[2, l-b]furan (R7000) in a medium-term rat liver bioassay
-
Cui L, Hasegawa R, Zajdela F, Puapairoj P, Shirai T, and Ito N. Lack of promoting activity of 7-methoxy-2-nitro-naphth-o-[2, l-b]furan (R7000) in a medium-term rat liver bioassay. Cancer Lett 1994; 76: 161-66.
-
(1994)
Cancer Lett
, vol.76
, pp. 161-166
-
-
Cui, L.1
Hasegawa, R.2
Zajdela, F.3
Puapairoj, P.4
Shirai, T.5
Ito, N.6
-
46
-
-
0028245956
-
Effect of ethanol on paraquat toxicity in F344 rats
-
Puapairoj P, Cui L, Ogawa K, Akagi K, Hasegawa R, and Ito N. Effect of ethanol on paraquat toxicity in F344 rats. Food Chem Toxicol 1994 ; 32 : 379-86.
-
(1994)
Food Chem Toxicol
, vol.32
, pp. 379-386
-
-
Puapairoj, P.1
Cui, L.2
Ogawa, K.3
Akagi, K.4
Hasegawa, R.5
Ito, N.6
-
47
-
-
0027252563
-
Strong inhibition of 2-amino-6-methyldipyrido[ 1
-
Hirose M, Akagi K, Hasegawa R, Satoh T, Nihno Y, Miki T, Sugimura T, and Ito N. Strong inhibition of 2-amino-6-methyldipyrido[ 1, 2-a ; 3ʹ, 2ʹ-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2, 3, 5-trimethylhydroquinone. Jpn J Cancer Res 1993 ; 84 : 481-84.
-
(1993)
3ʹ, 2ʹ-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2
, vol.3
, pp. 481-484
-
-
Hirose, M.1
Akagi, K.2
Hasegawa, R.3
Satoh, T.4
Nihno, Y.5
Miki, T.6
Sugimura, T.7
Ito, N.8
-
48
-
-
0029616654
-
-
Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6 methyldipyrido[1, 2-a : 3ʹ, 2ʹ-d] imidazole (Glu-P-l)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3, 8-dimethylimidazo [4, 5-f] quinoxaline (MelQx).
-
Hirose M, Hasegawa R, Kimura J, Akagi K, Yoshida Y, Tanaka H, Miki T, Satoh T, Wakabayashi K, Ito N, and Shirai T. Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6 methyldipyrido[1, 2-a : 3ʹ, 2ʹ-d] imidazole (Glu-P-l)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3, 8-dimethylimidazo [4, 5-f] quinoxaline (MelQx). Carcinogenesis 1995; 16: 3049-3055.
-
(1995)
Carcinogenesis
, vol.16
, pp. 3049-3055
-
-
Hirose, M.1
Hasegawa, R.2
Kimura, J.3
Akagi, K.4
Yoshida, Y.5
Tanaka, H.6
Miki, T.7
Satoh, T.8
Wakabayashi, K.9
Ito, N.10
Shirai, T.11
-
49
-
-
0029549760
-
Lack of promoting activity of four pesticides on induction of preneoplastic liver cell foci in rats
-
Kato T, Ogiso T, Kato K, Sano M, Hasegawa R, Shirai T, and Ito N. Lack of promoting activity of four pesticides on induction of preneoplastic liver cell foci in rats. Teratog Carcinog Mutag 1995; 15: 251-57.
-
(1995)
Teratog Carcinog Mutag
, vol.15
, pp. 251-257
-
-
Kato, T.1
Ogiso, T.2
Kato, K.3
Sano, M.4
Hasegawa, R.5
Shirai, T.6
Ito, N.7
-
50
-
-
21544451982
-
Effects of carbamate insecticides in a rat medium-term bioassay for hepatocarcinogens
-
Tanaka H, Hasegawa R, Takesada Y, Ogiso T, Hirose M, and Shirai T. Effects of carbamate insecticides in a rat medium-term bioassay for hepatocarcinogens. J Toxicol Environ Health 1996 ; 47: 493-98.
-
(1996)
J Toxicol Environ Health
, vol.47
, pp. 493-498
-
-
Tanaka, H.1
Hasegawa, R.2
Takesada, Y.3
Ogiso, T.4
Hirose, M.5
Shirai, T.6
-
51
-
-
0345300691
-
Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat
-
Futakuchi M, Lijinsky W, Hasegawa R, Hirose M, Ito N, and Shirai T. Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat. Cancer Lett 1996; 104: 37-41.
-
(1996)
Cancer Lett
, vol.104
, pp. 37-41
-
-
Futakuchi, M.1
Lijinsky, W.2
Hasegawa, R.3
Hirose, M.4
Ito, N.5
Shirai, T.6
-
52
-
-
0027763648
-
Hepatic peroxisome proliferation in rodents and its significance for humans
-
Bentley P, Calder I, Elcombe C, Grasso P, Stringer D, and Wiegand H-J. Hepatic peroxisome proliferation in rodents and its significance for humans. Food Chem Toxicol 1993 ; 31: 857-907.
-
(1993)
Food Chem Toxicol
, vol.31
, pp. 857-907
-
-
Bentley, P.1
Calder, I.2
Elcombe, C.3
Grasso, P.4
Stringer, D.5
Wiegand, H-J.6
-
53
-
-
0028172089
-
Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis
-
Ashby J, Brady A, Elcombe CR, Elliott BM, Ishmael J, Odun J, Tugwood JD, Kettle S, and Purchase IFH. Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum Exp Toxicol 1994; 13(Suppl 2): SI-SI 17.
-
(1994)
Hum Exp Toxicol
, pp. 17
-
-
Ashby, J.1
Brady, A.2
Elcombe, C.R.3
Elliott, B.M.4
Ishmael, J.5
Odun, J.6
Tugwood, J.D.7
Kettle, S.8
Purchase, I.F.H.9
-
54
-
-
0027397629
-
Tamoxifen induces hepatocellular carcinoma in rat liver: a 1 year study with two antiestrogens
-
Hirsimaki P, Hirsimaki Y, Nieminen L, and Payne BJ. Tamoxifen induces hepatocellular carcinoma in rat liver: a 1 year study with two antiestrogens. Arch Toxicol 1993; 67: 49-54.
-
(1993)
Arch Toxicol
, vol.67
, pp. 49-54
-
-
Hirsimaki, P.1
Hirsimaki, Y.2
Nieminen, L.3
Payne, B.J.4
-
55
-
-
0027254570
-
Enhancement by non-mutagenic pesticides of GST-P positive hepatic foci development initiated with diethylnitrosamine in the rat
-
Hoshiya T, Hasegawa R, Hakoi K, Cui L, Ogiso T, Cabral R, and Ito N. Enhancement by non-mutagenic pesticides of GST-P positive hepatic foci development initiated with diethylnitrosamine in the rat. Cancer Lett 1993 ; 72 : 59-64.
-
(1993)
Cancer Lett
, vol.72
, pp. 59-64
-
-
Hoshiya, T.1
Hasegawa, R.2
Hakoi, K.3
Cui, L.4
Ogiso, T.5
Cabral, R.6
Ito, N.7
-
56
-
-
0004160916
-
McMichael AJ. Complex Mixtures and Cancer Risk. IARC Scientific Publications, No
-
Vainio H, Sorsa M, and McMichael AJ. Complex Mixtures and Cancer Risk. IARC Scientific Publications, No. 104. Lyon: IARC, 1990.
-
(1990)
Lyon: IARC
, pp. 104
-
-
Vainio, H.1
Sorsa, M.2
-
57
-
-
0025760019
-
Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses
-
Ito N, Hasegawa R, Shirai T, Fukushima S, Hakoi K, Takaba K, Iwasaki S, Wakabayashi K, Nagao M, and Sugimura T. Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses. Carcinogenesis 1991; 12 : 767-72.
-
(1991)
Carcinogenesis
, vol.12
, pp. 767-772
-
-
Ito, N.1
Hasegawa, R.2
Shirai, T.3
Fukushima, S.4
Hakoi, K.5
Takaba, K.6
Iwasaki, S.7
Wakabayashi, K.8
Nagao, M.9
Sugimura, T.10
-
58
-
-
0026350770
-
Synergistic enhancement of glutathione S-transferase placental form-positive hepatic cell foci development in diethylnitrosamine-treated rats by combined administration of five heterocyclic amines at low doses
-
Hasegawa R, Shirai T, Hakoi K, Takaba K, Iwasaki S, Hoshiya T, Ito N, Nagao M, and Sugimura T. Synergistic enhancement of glutathione S-transferase placental form-positive hepatic cell foci development in diethylnitrosamine-treated rats by combined administration of five heterocyclic amines at low doses. Jpn J Cancer Res 1991 ; 82 : 1378-84.
-
(1991)
Jpn J Cancer Res
, vol.82
, pp. 1378-1384
-
-
Hasegawa, R.1
Shirai, T.2
Hakoi, K.3
Takaba, K.4
Iwasaki, S.5
Hoshiya, T.6
Ito, N.7
Nagao, M.8
Sugimura, T.9
-
59
-
-
0028179822
-
Synergistic enhancement of hepatic foci development by combined treatment of rats with 10 heterocyclic amines at low doses
-
Hasegawa R, Miyata E, Futakuchi M, Hagiwara A, Nagao M, Sugimura T, and Ito N. Synergistic enhancement of hepatic foci development by combined treatment of rats with 10 heterocyclic amines at low doses. Carcinogenesis 1994; 15: 1037-41.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1037-1041
-
-
Hasegawa, R.1
Miyata, E.2
Futakuchi, M.3
Hagiwara, A.4
Nagao, M.5
Sugimura, T.6
Ito, N.7
-
60
-
-
0029857907
-
Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat
-
Hasegawa R, Yoshimura I, Imaida K, Ito N, and Shirai T. Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat. Jpn J Cancer Res 1996, 87 ; 1125-33.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 1125-1133
-
-
Hasegawa, R.1
Yoshimura, I.2
Imaida, K.3
Ito, N.4
Shirai, T.5
-
61
-
-
0028298317
-
Biphasic modifying effect of indole-3-carbinol on diethylnitor-osamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats
-
Kim DJ, Lee KK, Han BS, Ahn B, Bae JH, and Jang JJ. Biphasic modifying effect of indole-3-carbinol on diethylnitor-osamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats. Jpn J Cancer Res 1994; 85: 578-83.
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 578-583
-
-
Kim, D.J.1
Lee, K.K.2
Han, B.S.3
Ahn, B.4
Bae, J.H.5
Jang, J.J.6
-
62
-
-
26844576040
-
Smith WC and, Richardson FC. Dose-dependent induction of GST-P+ staining foci by the rat hepatocarcinogen methapyrilene in the medium-term bioassay
-
Horn DM, Jordan WH, Holloway DC, Smith WC and, Richardson FC. Dose-dependent induction of GST-P+ staining foci by the rat hepatocarcinogen methapyrilene in the medium-term bioassay. Fund Appl Toxicol 1996 ; 29 : 19497.
-
(1996)
Fund Appl Toxicol
, vol.29
, pp. 19497
-
-
Horn, D.M.1
Jordan, W.H.2
Holloway, D.C.3
-
63
-
-
0027531048
-
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats
-
Hagiwara A, Tanaka H, Imaida K, Tamano S, Fukushima S, and Ito N. Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats. Jpn J Cancer Res 1993; 84 : 237-45.
-
(1993)
Jpn J Cancer Res
, vol.84
, pp. 237-245
-
-
Hagiwara, A.1
Tanaka, H.2
Imaida, K.3
Tamano, S.4
Fukushima, S.5
Ito, N.6
-
64
-
-
0027300414
-
Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats
-
Hasegawa R, Cabral R, Hoshiya T, Hakoi K, Ogiso T, Boonyaphiphat P, Shirai T, and Ito N. Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats. Int J Cancer 1993 ; 54 : 489-93.
-
(1993)
Int J Cancer
, vol.54
, pp. 489-493
-
-
Hasegawa, R.1
Cabral, R.2
Hoshiya, T.3
Hakoi, K.4
Ogiso, T.5
Boonyaphiphat, P.6
Shirai, T.7
Ito, N.8
-
65
-
-
0027203611
-
Effects of green tea catechins in a rat multi-organ carcinogenesis model
-
Hirose M, Hoshiya T, Akagi K, Takahashi S, Hara Y, and Ito N. Effects of green tea catechins in a rat multi-organ carcinogenesis model. Carcinogenesis 1993; 14: 1549-53.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1549-1553
-
-
Hirose, M.1
Hoshiya, T.2
Akagi, K.3
Takahashi, S.4
Hara, Y.5
Ito, N.6
-
66
-
-
0028805063
-
Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model
-
Shibata M-A, Hasegawa R, Imaida K, Hagiwara A, Ogawa K, Hirose M, Ito N, and Shirai T. Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model. Cancer Res 1995 ; 55 : 4870-74.
-
(1995)
Cancer Res
, vol.55
, pp. 4870-4874
-
-
Shibata, M-A.1
Hasegawa, R.2
Imaida, K.3
Hagiwara, A.4
Ogawa, K.5
Hirose, M.6
Ito, N.7
Shirai, T.8
-
67
-
-
0030037528
-
Lack of chemopreventive effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model
-
Kimura J, Takahashi S, Ogiso T, Yoshida Y, Akagi K, Hasegawa R, Kurata M, Hirose M, and Shirai T. Lack of chemopreventive effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model. Jpn J Cancer Res 1996 ; 87 : 589-94.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 589-594
-
-
Kimura, J.1
Takahashi, S.2
Ogiso, T.3
Yoshida, Y.4
Akagi, K.5
Hasegawa, R.6
Kurata, M.7
Hirose, M.8
Shirai, T.9
-
68
-
-
0025818622
-
Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model
-
Jang JJ, Cho KJ, Lee YS, and Bae JH. Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model. Carcinogenesis 1991 12, 691-95.
-
(1991)
Carcinogenesis
, vol.12
, pp. 691-695
-
-
Jang, J.J.1
Cho, K.J.2
Lee, Y.S.3
Bae, J.H.4
|