Long-term intracerebroventricular infusion of corticotropin-releasing hormone alters neuroendocrine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge

Journal of Neuroscience

Volumn 17, Issue 11, 1997, Pages 4448-4460

  Linthorst, Astrid C E ^a   Flachskamm, Cornelia ^a   Hopkins, Stephen J ^b   Hoadley, Margaret E ^b   Labeur, Marta S ^a   Holsboer, Florian ^a   Reul, Johannes M H M ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

biotelemetry; body temperature; corticosterone; corticotropin releasing hormone; endotoxin; hippocampus; hypothalamic pituitary adrenocortical axis; in vivo microdialysis; interleukin 1; interleukin 6; locomotion; rat; serotonin; sickness behavior

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; SEROTONIN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; FEVER; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; MALE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; RAT; STRESS; TELEMETRY;

EID: 0031006645     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-11-04448.1997     Document Type: Article

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