A novel fibronectin binding site required for fibronectin fibril growth during matrix assembly

Journal of Cell Biology

Volumn 154, Issue 5, 2001, Pages 1081-1088

  Sechler, Jan L ^a   Rao, Hongwei ^a   Cumiskey, Anne Marie ^a   Vega Colón, Irbert ^a   Smith, Michael S ^a   Murata, Takatoshi ^a   Schwarzbauer, Jean E ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Fibronectin; Matrix assembly; RGD sequence; Self association; Type III repeats

Indexed keywords

FIBRONECTIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; FIBER; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; EXTRACELLULAR MATRIX; FIBRONECTINS; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0035802114     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200102034     Document Type: Article

References (34)

1. Fibronectin self-association is mediated by complementary sites within the amino-terminal one-third of the molecule
2. The structure and stability of human plasma cold-insoluble globulin
3. Fibronectin fibrillo-genesis involves the heparin II binding domain of fibronectin
4. Formation of sodium dodecyl sulfate-stable fibronectin multimers
5. Monoclonal antibody to fibronectin which inhibits extracellular matrix assembly
6. Role of the I-9 and III-1 modules of fibronectin in the formation of an exttacellular fibronectin matrix
7. Reversible unfolding offibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin
8. Fibronection in extended and compact conformations. Electron microscopy and sedimentation analysis
9. Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin
10. A novel role for the integrin-binding III-10 module in fibronectin matrix assembly
11. Cryptic self-association sites in type III modules of fibronectin
12. The compact conformation of fibronectin is determined by intramolecular ionic interactions
13. Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch
14. Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix
15. Binding of plasma fibronectin to cell layers of human skin fibroblasts
16. Interaction of the 70,000-mol. wt. amino terminal fragment of fibronectin with matrix-assembly receptor of fibroblasts
17. A fibtonectin self-assembly site involved in fibronectin matrix assembly: Reconstruction in a synthetic peptide
18. Superfibronectin is a functionally distinct form of fibronectin
19. 5 repeat contains a novel cell adhesion sequence, KLDAPT, which binds activated α4β1 and α4β7 integtins
20. Dependence of the shape of the plasma fibronectin molecule on solvent composition
21. Identification of the fibronectin sequences required for assembly of a fibrillat matrix
22. Fibronectin fibrillogenesis: A paradigm for extracellular matrix assembly
23. Modulatory roles for integrin activation and the synergy site of fibronectin during matrix assembly
24. A novel RGD-independent fibronectin assembly pathway initiated by α4β1 integrin binding to the alternatively spliced V region
25. Altered rate of fibronectin matrix assembly by deletion of the first type III repeats
26. Five type I modules of fibronectin form a functional unit that binds to fibroblasts and Staphylococcus aureus
27. N-terminal type I modules required for fibronectin binding to fibroblasts and to fibtonectin's III1 module
28. Conformational transitions in the cell binding domain of fibronectin
29. β1 integrin-dependent and -independent polymerization of fibronectin
30. Conformational states of fibronectin. Effects of pH, ionic strength, and collagen-binding
31. Integrin activation and cytoskeletal interaction are critical steps in the assembly of a fibronectin matrix
32. Identification of a new biological function for the integtin αvβ3: Initiation of fibronectin matrix assembly