Synthesis of N-Fmoc 3-(4-(di-(tert-butyl)phosphonomethyl)-phenyl)pipecolic acid as a conformationally constrained phosphotyrosyl mimetic suitably protected for peptide synthesis

Tetrahedron

Volumn 58, Issue 52, 2002, Pages 10423-10428

  Liu, Ding Guo ^a   Wang, Xiang Zhu ^a   Gao, Yang ^a   Li, Bihua ^b   Yang, Dajun ^b   Burke Jr , Terrence R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Inhibitor; Mimetic; Tripeptide

Indexed keywords

AMINO ACID DERIVATIVE; KETONE DERIVATIVE; N 9 FLUORENYLMETHYLOXYCARBONYL 3 [4 [DI (TERT BUTYL)PHOSPHONOMETHYL]PHENYL]PIPECOLIC ACID; PHOSPHORUS DERIVATIVE; PIPECOLIC ACID DERIVATIVE; PROTEIN; PROTEIN SH2; TRIPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHIRALITY; CONFORMATION; ENANTIOSELECTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEOMETRY; HYDROLYSIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; STEREOCHEMISTRY; SYNTHESIS;

EID: 0037164662     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(02)01421-7     Document Type: Article

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