Enantioselective synthesis of Nα-Fmoc protected (2S,3R)-3-phenylpipecolic acid. A constrained phenylalanine analogue suitably protected for solid-phase peptide synthesis

Journal of Organic Chemistry

Volumn 67, Issue 5, 2002, Pages 1448-1452

  Liu, Ding Guo ^a   Gao, Yang ^a   Wang, Xiangzhu ^a   Kelley, James A ^a   Burke Jr , Terrence R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOLID PHASE PEPTIDE SYNTHESIS;

CONFORMATIONS; STEREOCHEMISTRY; TORSION TESTING;

ORGANIC COMPOUNDS;

3 PHENYLPIPECOLIC ACID; PHENYLALANINE DERIVATIVE; PIPECOLIC ACID; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BROMINATION; CHIRALITY; CONFORMATIONAL TRANSITION; PEPTIDE SYNTHESIS; REACTION ANALYSIS; SOLID PHASE EXTRACTION; STEREOCHEMISTRY;

CARBOXYLIC ACIDS; CATALYSIS; FLUORENES; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; OXAZOLES; PEPTIDES; PHENYLALANINE; PIPECOLIC ACIDS; STEREOISOMERISM;

EID: 0037040647     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo010124+     Document Type: Article

References (22)