-
1
-
-
0034199806
-
The role of oncogenic kinases in human cancer
-
Tsatsanis C, Spandidos DA. The role of oncogenic kinases in human cancer (review). Int J Mol Med 2000;5:583-90.
-
(2000)
Int J Mol Med
, vol.5
, pp. 583-590
-
-
Tsatsanis, C.1
Spandidos, D.A.2
-
2
-
-
0034777519
-
Ras signaling pathway proteins as therapeutic targets
-
Adjei AA. Ras signaling pathway proteins as therapeutic targets, Curr Pharm Des 2001;7:1581-94.
-
(2001)
Curr Pharm Des
, vol.7
, pp. 1581-1594
-
-
Adjei, A.A.1
-
3
-
-
0034788453
-
Tyrosine kinase inhibitors: From rational design to clinical trials
-
Traxler P, Bold G, Buchdunger E, Caravatti G, Furet P, Manley P, O'Reilly T, Wood J, Zimmermann J., Traxler P, Bold G, Buchdunger E, et al. Tyrosine kinase inhibitors: from rational design to clinical trials. Med Res Rev 2001;21:499-512.
-
(2001)
Med Res Rev
, vol.21
, pp. 499-512
-
-
Traxler, P.1
Bold, G.2
Buchdunger, E.3
Caravatti, G.4
Furet, P.5
Manley, P.6
O'Reilly, T.7
Wood, J.8
Zimmermann, J.9
Traxler, P.10
Bold, G.11
Buchdunger, E.12
-
4
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, Lydon NB, Kantarjian H, Capdeville R, Ohno-Jones S, Sawyers CL. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344:1031-7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
5
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
-
Tuveson DA, Willis NA, Jacks T, Griffin JD, Singer S, Fletcher CD, Fletcher JA, Demetri GD. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene 2000;20:5054-8.
-
(2000)
Oncogene
, vol.20
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
Griffin, J.D.4
Singer, S.5
Fletcher, C.D.6
Fletcher, J.A.7
Demetri, G.D.8
-
6
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, Fleming T, Eiermann W, Wolter J, Pegram M, Baselga J, Norton L. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
8
-
-
0035403876
-
Approval heralds new generation of kinase inhibitors
-
Fletcher L. Approval heralds new generation of kinase inhibitors. Nature Biotech 2001;19:599-600.
-
(2001)
Nature Biotech
, vol.19
, pp. 599-600
-
-
Fletcher, L.1
-
9
-
-
0034799139
-
A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
-
Ciardiello F, Tortora G. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin Cancer Res 2001;7:2958-70.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2958-2970
-
-
Ciardiello, F.1
Tortora, G.2
-
10
-
-
0030910482
-
Humanization of a mouse monoclonal antibody that blocks the EGF-R: Recovery of antagonistic activity
-
Mateo C, Moreno E, Amour K, Lombardero J, Harris W, Pérez R. Humanization of a mouse monoclonal antibody that blocks the EGF-R: recovery of antagonistic activity. Immunotechnology 1997; 3:71-81.
-
(1997)
Immunotechnology
, vol.3
, pp. 71-81
-
-
Mateo, C.1
Moreno, E.2
Amour, K.3
Lombardero, J.4
Harris, W.5
Pérez, R.6
-
11
-
-
0027530122
-
Acquired multicellular-mediated resistance to alkylating agents in cancer
-
Kobayashi H, Man S, Graham CH, Kapitain SJ, Teicher BA, Kerbel RS. Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc Natl Acad Sci USA 1993;90:3294-8.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3294-3298
-
-
Kobayashi, H.1
Man, S.2
Graham, C.H.3
Kapitain, S.J.4
Teicher, B.A.5
Kerbel, R.S.6
-
12
-
-
0034074638
-
Humanized versus murine anti-human epidemal growth factor receptor monoclonal antibodies for immunoscintographic studies
-
Morales AA, Duconge J, Alvarez-Ruiz D, Becquer-Viart ML, Nunez-Gandolff G, Fernandez E, Caballero-Torres I, Iznaga-Escobar N. Humanized versus murine anti-human epidemal growth factor receptor monoclonal antibodies for immunoscintographic studies. Nucl Med Biol 2000;27:199-206.
-
(2000)
Nucl Med Biol
, vol.27
, pp. 199-206
-
-
Morales, A.A.1
Duconge, J.2
Alvarez-Ruiz, D.3
Becquer-Viart, M.L.4
Nunez-Gandolff, G.5
Fernandez, E.6
Caballero-Torres, I.7
Iznaga-Escobar, N.8
-
13
-
-
0028819660
-
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
-
Goldstein NI, Prewett M, Zuklys K, Rockwell P, Mendelsohn J. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res 1995;1:311-8.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 311-318
-
-
Goldstein, N.I.1
Prewett, M.2
Zuklys, K.3
Rockwell, P.4
Mendelsohn, J.5
-
14
-
-
0034489914
-
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
-
Sirotnak FM, Zakowski MF, Miller VA, Scher HI, Kris MG. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 2000;6:4885-92.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4885-4892
-
-
Sirotnak, F.M.1
Zakowski, M.F.2
Miller, V.A.3
Scher, H.I.4
Kris, M.G.5
-
16
-
-
0031039923
-
Transforming growth factor alpha induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene that requires AP-2 dependent DNA binding and transactivation
-
Gille J, Swerlick RA, Caughman SW. Transforming growth factor alpha induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene that requires AP-2 dependent DNA binding and transactivation. Embo J 1997;16:750-9.
-
(1997)
Embo J
, vol.16
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
17
-
-
0027412319
-
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
-
Goldman CK, Kim J, Wong WL, King V, Brock T, Gillespie GY. Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 1993;4:121-33.
-
(1993)
Mol Biol Cell
, vol.4
, pp. 121-133
-
-
Goldman, C.K.1
Kim, J.2
Wong, W.L.3
King, V.4
Brock, T.5
Gillespie, G.Y.6
-
18
-
-
16144362509
-
Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A
-
Ciardiello F, Damiano V, Bianco R, Bianco C, Fontanini G, De Laurentiis M, De Placido S, Mendelsohn J, Bianco AR, Tortora G. Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A. J Natl Cancer Inst 1996;88:1770-6.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1770-1776
-
-
Ciardiello, F.1
Damiano, V.2
Bianco, R.3
Bianco, C.4
Fontanini, G.5
De Laurentiis, M.6
De Placido, S.7
Mendelsohn, J.8
Bianco, A.R.9
Tortora, G.10
-
19
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
Perrotte P, Matsumoto T, Inoue K, Kuniyasu H, Eve BY, Hicklin DJ, Radinsky R, Dinney CP. Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res 1999;5:257-65.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
Kuniyasu, H.4
Eve, B.Y.5
Hicklin, D.J.6
Radinsky, R.7
Dinney, C.P.8
-
20
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
Viloria-Petit AM, Rak J, Hung MC, Rockwell P, Goldstein N, Fendly B, Kerbel RS. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 1997;151:523-30.
-
(1997)
Am J Pathol
, vol.151
, pp. 523-530
-
-
Viloria-Petit, A.M.1
Rak, J.2
Hung, M.C.3
Rockwell, P.4
Goldstein, N.5
Fendly, B.6
Kerbel, R.S.7
-
21
-
-
0026767229
-
A new monoclonal antibody for detection of the EGF-R in Western Blot and paraffin embedded tissue sections
-
Fernandez A, Spitzer E, Perez R, Boehmer FD, Eckert K, Zschiesche W, Grosse R. A new monoclonal antibody for detection of the EGF-R in Western Blot and paraffin embedded tissue sections. J Cell Biochem 1992;49:157-65.
-
(1992)
J Cell Biochem
, vol.49
, pp. 157-165
-
-
Fernandez, A.1
Spitzer, E.2
Perez, R.3
Boehmer, F.D.4
Eckert, K.5
Zschiesche, W.6
Grosse, R.7
-
22
-
-
0021154199
-
Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells
-
Xu YH, Ishii S, Clark AJ, Sullivan M, Wilson RK, Ma DP, Roe BA, Merlino GT, Pastan I. Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature 1984;309:806-10.
-
(1984)
Nature
, vol.309
, pp. 806-810
-
-
Xu, Y.H.1
Ishii, S.2
Clark, A.J.3
Sullivan, M.4
Wilson, R.K.5
Ma, D.P.6
Roe, B.A.7
Merlino, G.T.8
Pastan, I.9
-
23
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, Dull TJ, Gray A, Tam AW, Lee J, Yarden Y, Libermann TA, Schlessinger J. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984;309: 418-25.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
Dull, T.J.4
Gray, A.5
Tam, A.W.6
Lee, J.7
Yarden, Y.8
Libermann, T.A.9
Schlessinger, J.10
-
24
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000;19:6550-65.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
26
-
-
0027999356
-
Effects of antiepidermal growth factor receptor antibody 528 on the proliferation and differentiation of head and neck cancer
-
Sturgis EM, Sacks PG, Masui H, Mendelsohn J, Schantz SP. Effects of antiepidermal growth factor receptor antibody 528 on the proliferation and differentiation of head and neck cancer. Otolaryngol Head Neck Surg 1994;111:633-45.
-
(1994)
Otolaryngol Head Neck Surg
, vol.111
, pp. 633-645
-
-
Sturgis, E.M.1
Sacks, P.G.2
Masui, H.3
Mendelsohn, J.4
Schantz, S.P.5
-
27
-
-
0029670014
-
Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody
-
Wu X, Rubin M, Fan Z, DeBlasio T, Soos T, Koff A, Mendelsohn J. Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody. Oncogene 1996;12:1397-403.
-
(1996)
Oncogene
, vol.12
, pp. 1397-1403
-
-
Wu, X.1
Rubin, M.2
Fan, Z.3
DeBlasio, T.4
Soos, T.5
Koff, A.6
Mendelsohn, J.7
-
28
-
-
0029776415
-
Antiepidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145
-
Peng D, Fan Z, Lu Y, DeBlasio T, Scher H, Mendelsohn J. Antiepidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145. Cancer Res 1996;56:3666-9.
-
(1996)
Cancer Res
, vol.56
, pp. 3666-3669
-
-
Peng, D.1
Fan, Z.2
Lu, Y.3
DeBlasio, T.4
Scher, H.5
Mendelsohn, J.6
-
29
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK, Arnold L, Boman B, Cunningham A, DiOrio C, Doty J, Morin MJ, Moyer MP, Neveu M, Pollack VA, et al. Induction of apoptosis and cell cycle arrest by CP-358774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997;57:4838-48.
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
Arnold, L.4
Boman, B.5
Cunningham, A.6
DiOrio, C.7
Doty, J.8
Morin, M.J.9
Moyer, M.P.10
Neveu, M.11
Pollack, V.A.12
-
30
-
-
0024549349
-
Induction of angiogenesis during the transition from hyperplasia to neoplasia
-
Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989; 339:58-61.
-
(1989)
Nature
, vol.339
, pp. 58-61
-
-
Folkman, J.1
Watson, K.2
Ingber, D.3
Hanahan, D.4
-
31
-
-
0001042452
-
Vascular endothelial growth factor/vascular permeability factor: Multiple biological activities for promoting angiogenesis
-
Voest EE, D'Amore P. New York: Marcel Decker
-
Senger DR. Vascular endothelial growth factor/vascular permeability factor: multiple biological activities for promoting angiogenesis. In: Voest EE, D'Amore P. Tumor angiogenesis and microcirculation. New York: Marcel Decker, 2001. 167-84.
-
(2001)
Tumor angiogenesis and microcirculation
, pp. 167-184
-
-
Senger, D.R.1
-
33
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996;380:439-42.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
34
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-9.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
-
35
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
-
Cheng SY, Huang HJ, Nagane M, Ji XD, Wang D, Shih CC, Arap W, Huang CM, Cavenee WK. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci USA 1996;93: 8502-7.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8502-8507
-
-
Cheng, S.Y.1
Huang, H.J.2
Nagane, M.3
Ji, X.D.4
Wang, D.5
Shih, C.C.6
Arap, W.7
Huang, C.M.8
Cavenee, W.K.9
-
36
-
-
0030059075
-
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
-
Melnyk O, Shuman MA, Kim KJ. Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth. Cancer Res 1996;56:921-4.
-
(1996)
Cancer Res
, vol.56
, pp. 921-924
-
-
Melnyk, O.1
Shuman, M.A.2
Kim, K.J.3
-
37
-
-
0029863730
-
Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo
-
Millauer B, Longhi MP, Plate KH, Shawver LK, Risau W, Ullrich A, Strawn LM. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo. Cancer Res 1996;56:1615-20.
-
(1996)
Cancer Res
, vol.56
, pp. 1615-1620
-
-
Millauer, B.1
Longhi, M.P.2
Plate, K.H.3
Shawver, L.K.4
Risau, W.5
Ullrich, A.6
Strawn, L.M.7
-
38
-
-
0032698140
-
Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors
-
Prewett M, Huber J, Li Y, Santiago A, O'Connor W, King K, Overholser J, Hooper A, Pytowski B, Witte L, Bohlen P, Hicklin DJ. Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors. Cancer Res 1999;59:5209-18.
-
(1999)
Cancer Res
, vol.59
, pp. 5209-5218
-
-
Prewett, M.1
Huber, J.2
Li, Y.3
Santiago, A.4
O'Connor, W.5
King, K.6
Overholser, J.7
Hooper, A.8
Pytowski, B.9
Witte, L.10
Bohlen, P.11
Hicklin, D.J.12
-
39
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, Hicklin D, Bohlen P, Schlaeppi JM, Rak J, Kerbel RS. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res 2001;1:5090-101.
-
(2001)
Cancer Res
, vol.1
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
Hicklin, D.4
Bohlen, P.5
Schlaeppi, J.M.6
Rak, J.7
Kerbel, R.S.8
-
40
-
-
0030005902
-
Antiangiogenic therapy of transgenic mice impairs de novo tumor growth
-
Parangi S, O'Reilly M, Christofori G, Holmgren L, Grosfeld J, Folkman J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. PNAS 1996;93:2002-7.
-
(1996)
PNAS
, vol.93
, pp. 2002-2007
-
-
Parangi, S.1
O'Reilly, M.2
Christofori, G.3
Holmgren, L.4
Grosfeld, J.5
Folkman, J.6
Hanahan, D.7
-
41
-
-
0034532027
-
The control of microvascular survival
-
Benjamin LE. The control of microvascular survival. Cancer Metastasis Rev 2000;19:75-81.
-
(2000)
Cancer Metastasis Rev
, vol.19
, pp. 75-81
-
-
Benjamin, L.E.1
-
42
-
-
0035906852
-
Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway
-
Clarke K, Smith K, Gullick WJ, Harris AL. Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway. Br J Cancer 2001;84:1322-9.
-
(2001)
Br J Cancer
, vol.84
, pp. 1322-1329
-
-
Clarke, K.1
Smith, K.2
Gullick, W.J.3
Harris, A.L.4
-
43
-
-
0027818836
-
Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies
-
Fan Z, Masui H, Altas I, Mendelsohn J. Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res 1993;53:4322-8.
-
(1993)
Cancer Res
, vol.53
, pp. 4322-4328
-
-
Fan, Z.1
Masui, H.2
Altas, I.3
Mendelsohn, J.4
-
44
-
-
0032844121
-
Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer. Herceptin Multinational Investigator Study Group
-
Shak S. Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer. Herceptin Multinational Investigator Study Group. Semin Oncol 1999;26:71-7.
-
(1999)
Semin Oncol
, vol.26
, pp. 71-77
-
-
Shak, S.1
-
45
-
-
0033966576
-
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
-
Milas L, Mason K, Hunter N, Petersen S, Yamakawa M, Ang K, Mendelsohn J, Fan Z. In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res 2000;6:701-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 701-708
-
-
Milas, L.1
Mason, K.2
Hunter, N.3
Petersen, S.4
Yamakawa, M.5
Ang, K.6
Mendelsohn, J.7
Fan, Z.8
-
46
-
-
0034084314
-
Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
-
Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000;6:2166-74.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2166-2174
-
-
Huang, S.M.1
Harari, P.M.2
-
47
-
-
0035398021
-
Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
-
Robert F, Ezekiel MP, Spencer SA, Meredith RF, Bonner JA, Khazaeli MB, Saleh MN, Carey D, LoBuglio AF, Wheeler RH, Cooper MR, Waksal HW. Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J Clin Oncol 2001;19:3234-43.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3234-3243
-
-
Robert, F.1
Ezekiel, M.P.2
Spencer, S.A.3
Meredith, R.F.4
Bonner, J.A.5
Khazaeli, M.B.6
Saleh, M.N.7
Carey, D.8
LoBuglio, A.F.9
Wheeler, R.H.10
Cooper, M.R.11
Waksal, H.W.12
-
48
-
-
19244366949
-
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
Baselga J, Pfister D, Cooper MR, Cohen R, Burtness B, Bos M, D'Andrea G, Seidman A, Norton L, Gunnett K, Falcey J, Anderson V, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000;18:904-14.
-
(2000)
J Clin Oncol
, vol.18
, pp. 904-914
-
-
Baselga, J.1
Pfister, D.2
Cooper, M.R.3
Cohen, R.4
Burtness, B.5
Bos, M.6
D'Andrea, G.7
Seidman, A.8
Norton, L.9
Gunnett, K.10
Falcey, J.11
Anderson, V.12
|