Humanized versus murine anti-human epidermal growth factor receptor monoclonal antibodies for immunoscintigraphic studies

Nuclear Medicine and Biology

Volumn 27, Issue 2, 2000, Pages 199-206

  Morales, Alejo A Morales ^a   Ducongé, Jorge ^b   Alvarez Ruiz, Daniel ^b   Becquer Viart, Maria De Los Angeles ^b   Núñez Gandolff, Gilda ^a   Fernández, Eduardo ^b   Caballero Torres, Idania ^a   Iznaga Escobar, Normando ^a  

^a CENTER OF MOLECULAR IMMUNOLOGY   (Cuba)

^b UNIVERSITY OF HAVANA   (Cuba)

Author keywords

Biodistribution; Humanized antibodies Radiolabeling; Monoclonal antibodies; Nude mice

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; IMMUNOSCINTIGRAPHY; ISOTOPE LABELING; MOUSE; NONHUMAN; SQUAMOUS CELL CARCINOMA;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CARCINOMA, SQUAMOUS CELL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FREEZE DRYING; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS, GLANDULAR AND EPITHELIAL; RADIOIMMUNOASSAY; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SULFHYDRYL COMPOUNDS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0034074638     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00094-3     Document Type: Article

References (37)

1. 99mTc-labeled anti-CEA antibody to tumor immunoscintigraphy, first clinical results. Nucl. Med. Commun. 10:1989;345-352.
2. 111I-labeled anticarcioembryonic antigen monoclonal antibody. Cancer Res. 46:1986;6494-6502.
3. Dadparvar S., Krishna L., Miyamoto C., Brady L.W., Brown S.J., Bender H., Slizofski W.J., Eshleman J., Chevres A., Woo D.V. Indium-111-labeled anti-EGF-r-425 scintigraphy in the detection of malignant gliomas. Cancer. 73:1994;884-889.
4. Divgi C.R., Welt S., Kris M. Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma. J. Natl. Cancer Inst. 83:1991;97-104.
5. Divgi C.R., McDermott K., Johnson D.K., Schnobrich K.E., Finn R.D., Cohen A.M., Larson S.M. Detection of hepatic metastases from colorectal carcinoma using indium-111 (111In) labeled monoclonal antibody (mAb) MSKCC experience with mAb 111In-C110 . Int. J. Rad. Appl. Instrum. [B]. 18:(7):1991;705-710.
6. Ellman G.L. Tissue sulphydryl groups. Arch. Biochem. Biophys. 82:1959;70-77.
7. Epenetos A.A., Carr D., Johnson P.M., Bodmer W.F., Lavender J.P. Antibody-guide radiolocalization of tumor in patient with testicular or ovarian cancer using two radioiodinated antibodies to placental alkaline phosphatase. Br. J. Radiol. 59:1986;117-125.
8. Fernández A., Pérez R., Macias A., Velandia A., Alvarez I., Ramos M., Velozo A. Generación y caracterización primaria de anticuerpos monoclonales contra el receptor del factor de crecimiento epidérmico. Interferón y Biotecnología. 6:1989;289-299.
9. Fernández A., Spitzer E., Pérez R., Boehmer F.D., Eckert K., Zschiesche W., Grosse R. A new monoclonal antibody for detection of EGF-receptors in Western blots and paraffin-embedded tissue sections. J. Cell Biochem. 49:1992;157-165.
10. 99mTc using N2S2 ligands. J. Nucl. Med. 27:1986;957-958.
11. Goldenberg D.M., Kim E.E., Bennett S., Nelson M.O., Deland F.H. CEA radioimmunodetection in the evaluation of colorectal cancer and in the detection of occult neoplasm. Gastroenterology. 84:1983;524-532.
12. 123I-labeled monoclonal antibody imaging in ovarian cancer. J. Clin. Oncol. 4:1986;730-736.
13. 99mTc-labeled monclonal CEA antibody in the follow-up of colorectal cancer and other tumor producing CEA. Br. J. Cancer. 62:1990;34-36.
14. Iznaga N., Morales A., Ñúñez G. Micromethod for quantification of SH groups generated after reduction of monoclonal antibodies. Nucl. Med. Biol. 23:1996;641-644.
15. Lindmo T., Boven E., Cuttitta F., Fedorko J., Bunn P.A. Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess. J. Immunol. Methods. 72:1984;77-89.
16. Macias A., Pérez R., Lage A. Estudios sobre el factor de crecimiento epidérmico (EGF) II Desarrollo de un radioreceptor analisis para la determinación de cantidades picomolares . Interferon y Biotecnología. 2:1985;115-127.
17. Magnusson I., Rosen A.V., Nilsson R., Macias A., Pérez R., Skoog L. Receptors for epidermal growth factor and sex steroid hormones in human colorectal carcinomas. Anticancer Res. 9:1989;299-302.
18. Mateo C., Moreno E., Amour K., Lombardero J., Harris W., Pérez R. Humanization of a mouse monoclonal antibody that blocks the epidermal growth factor receptor Recovery of antagonistic activity . Immunotechnology. 3:1997;71-81.
19. Mateo C., Moreno E., Amour K., Lombardero J., Harris W., Pérez R. Humanization of a mouse monoclonal antibody that blocks the epidermal growth factor receptor Recovery of antagonistic activity . Immunotechnology. 3:1997;71-81.
20. Mather S.J., Ellison D. Reduction mediated technetium-99m labeling of monoclonal antibody. J. Nucl. Med. 31:1990;692-697.
21. Morales A., Zayas F., Núñez G., Iznaga N., Pérez N., Izquierdo J.C. Technetium-99m direct radiolabeling of monoclonal antibody ior egf/r3. Nucl. Med. Biol. 25:1998;25-30.
22. Munson P., Rodbard D. Ligand A versatile computerized approach for characterization of ligand-binding system . Anal. Biochem. 107:1980;120-139.
23. Murthy U., Basu A., Rodeck U., Herlyn M., Ross A.H., Das M. Binding of antagonistic monoclonal antibody to an intact and fragmented EGF-receptor polypeptide. Arch. Biochem. Biophys. 72:1987;77-89.
24. Neal D.E., March C., Benett M.K., Abel P.D., Hall R.R., Sainsbury J.R.C., Harris A.L. Epidermal growth factor receptors in human bladder cancer. Comparison of invasive and superficial tumors. Lancet. 1:1985;346-348.
25. Pérez R., Pascual M.R., Macias A., Lage A. Epidermal growth factor receptors in human breast cancer. Breast Cancer Res. Treat. 4:1984;189-193.
26. Rhodes B.C., Zamora P.O., Newell K.D., Valdez E.F. Technetium-99m labeling of murine monoclonal antibody fragments. J. Nucl. Med. 27:1986;685-693.
27. Rios M.A., Fernández A., Tormo B.R., Quintero S., Pérez I., Skoog L., Pérez R. Heterogeneous expression of the EGF-receptor in human breast carcinoma. Anticancer Res. 12:1992;205-208.
28. 99mTc como diagnóstico de cáncer de origen epitelial [Abstract]. Rev. Esp. Med. Nucl. 14, 285.
29. Rygaard J., Povosen C.O. Heterotransplantation of a human malignant tumor to nude mice. Acta Pathol. Microbiol. Scand. 77:1969;758-760.
30. Schwarz A. and Steinstrasser A. (1987). A novel approach to Tc-99m-labeled monoclonal antibodies [abstract]. J. Nucl. Med. 28, 721.
31. Snelling L., Miyamoto C.T., Bender H., Brady L.W., Steplewski Z., Class R. Epidermal growth factor receptor 425 monoclonal antibodies radiolabeled with Iodine-125 in the adjuvant treatment of high-grade astrocytomas. Hybridoma. 14:1995;111-114.
32. Takahashi H., Nakazawa S., Herlyn D. Experimental radioimmunotherapy of a xenografted human glioma using 131I-labeled monoclonal antibody to epidermal growth factor receptor. Neurol. Med. Chir. (Tokyo). 33:1993;610-615.
33. 99mTc-HSA. J. Nucl. Med. 19:1976;796-803.
34. Vázquez A.M., Tormo B.R., Alfonso M., Velandia A., Fernández L.E., Giscombe R., Ansotegui I., Jeddi-Tehrani M., Cedeño M., Toledo A.L., Pérez R., Mellstedt H., Biberfeld P. Characterization of ior C5 colorectal tumor associated antigen. Inmunología Española. 14:1995;130-132.
35. Vázquez A.M., Tormo B.R., Velandia A., Giscombe R., Ansotegui I., Jeddi-Tehroni M., Pérez R., Mellstedt H., Biberfeld P. Characterization of colorectal antigen ior C2. Hybridoma. 11:1992;245-256.
36. Vázquez A.M., Tormo B.R., Velandia A., Gómez C.A., Alfonso M., Giscombe R., Ansotegui I., Jeddi-Tehrani M., Pérez R., Mellstedt H., Biberfeld P. Characterization of the colorectal antigen ior C2. II. Year Immunol. 7:1993;137-145.
37. Veale D., Ashcroft T., March C., Gibson G.J., Harris A.L. Epidermal growth factor receptors in non-small cell lung cancer. Br. J. Cancer. 55:1987;513-516.