Antiangiogenic therapy of transgenic mice impairs de novo tumor growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 5, 1996, Pages 2002-2007

  Parangi, Sareh ^a,b   O'Reilly, Michael ^b   Christofori, Gerhard ^a,c   Holmgren, Lars ^b,d   Grosfeld, Jeffrey ^b   Folkman, Judah ^b   Hanahan, Douglas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

angiogenesis inhibitors; antitumor therapy; apoptosis; interferon; TNP 470; tumor angiogenesis

Indexed keywords

ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC ANTIBIOTIC; BETA INTERFERON; CYTOKINE; FUMAGILLOL CHLOROACETYLCARBAMATE; MINOCYCLINE; PLASMINOGEN; THROMBOSPONDIN;

ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; GROWTH INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SOLID TUMOR; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSGENIC MOUSE; TUMOR BLOOD FLOW; TUMOR GROWTH;

ADENOMA, ISLET CELL; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL DIVISION; CYCLOHEXANES; INTERFERON TYPE I; MICE; MICE, TRANSGENIC; MINOCYCLINE; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; S PHASE; SESQUITERPENES;

EID: 0030005902     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.5.2002     Document Type: Article

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