Bioprocess applications of a sindbis virus-based temperature-inducible expression system

Biotechnology and Bioengineering

Volumn 79, Issue 6, 2002, Pages 602-609

  Boorsma, M ^a,b,c   Hoenke, S ^a   Marrero, A ^b   Fischer, R ^b   Bailey, J E ^b   Renner, W A ^a   Bachmann, M F ^a  

^a CYTOS BIOTECHNOLOGY AG   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c DSM RESOLVE   (Netherlands)

Author keywords

Inducible expression; Interferon; PCytTS; Recombinant protein production; Selection

Indexed keywords

BETA INTERFERON; BIOLOGICAL MARKER; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHOTOPROTEIN; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CULTURE TECHNIQUE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; KIDNEY; METABOLISM; METHODOLOGY; MOLECULAR CLONING; REPLICON; SINDBIS VIRUS; TEMPERATURE; BIOPROCESS; CELL CULTURE; CYTOKINE PRODUCTION; HUMAN CELL; MUTATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TEMPERATURE DEPENDENCE; THERMOREGULATION;

ANIMALS; BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CELL LINE; CLONING, MOLECULAR; CRICETINAE; GENE EXPRESSION REGULATION, VIRAL; GREEN FLUORESCENT PROTEINS; HUMANS; INTERFERON-BETA; KIDNEY; LUMINESCENT PROTEINS; RECOMBINANT FUSION PROTEINS; REPLICON; SINDBIS VIRUS; TEMPERATURE; TRANSFECTION; ANIMAL; CELL CULTURE; HAMSTERS; HUMAN;

CELL CULTURE; CELLS; CLONING; PROTEINS; RNA; VIRUSES;

TEMPERATURE-INDUCIBLE EXPRESSION SYSTEMS;

BIOTECHNOLOGY;

SINDBIS VIRUS;

EID: 0037144081     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10311     Document Type: Article

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