Comparative analysis of two controlled proliferation strategies regarding product quality, influence on tetracycline-regulated gene expression, and productivity

Biotechnology and Bioengineering

Volumn 72, Issue 6, 2001, Pages 592-602

  Kaufmann, Hitto ^a   Mazur, Xenia ^a,b   Marone, Romina ^a   Bailey, James E ^a   Fussenegger, Martin ^a  

^a ETH ZURICH   (Switzerland)

^b SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

Controlled proliferation; Glycosylation; Low temperature

Indexed keywords

ALKALINE PHOSPHATASE; GLYCOPROTEIN; MESSENGER RNA; PROTEIN P27; TETRACYCLINE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHO CELL; GENE EXPRESSION REGULATION; GROWTH INHIBITION; LOW TEMPERATURE; NONHUMAN; NORTHERN BLOTTING; PRODUCTIVITY; PROTEIN QUALITY; SIALYLATION; TECHNIQUE; TWO DIMENSIONAL ELECTROPHORESIS;

ALKALINE PHOSPHATASE; ANIMALS; BLOTTING, NORTHERN; CELL CULTURE TECHNIQUES; CELL CYCLE PROTEINS; CELL DIVISION; CHO CELLS; CRICETINAE; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION; QUALITY CONTROL; RNA; TEMPERATURE; TETRACYCLINE; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0035916852     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20010320)72:6<592::AID-BIT1024>3.0.CO;2-J     Document Type: Article

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