Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2

Journal of Medicinal Chemistry

Volumn 43, Issue 13, 2000, Pages 2506-2513

  Otyepka, Michal ^a   Kryštof, Vladimír ^a   Havlíček, Libor ^b   Siglerová, Věra ^c   Strnad, Miroslav ^a   Koča, Jaroslav ^d  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF EXPERIMENTAL BOTANY   (Czech Republic)

^d MASARYK UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PURINE DERIVATIVE;

ARTICLE; CELL DIVISION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBUNIT; MOLECULAR MODEL; X RAY ANALYSIS;

CATALYTIC DOMAIN; CDC2 PROTEIN KINASE; CDC2-CDC28 KINASES; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; DRUG DESIGN; ENZYME INHIBITORS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0342757880     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990506w     Document Type: Article

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