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Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1587, Issue 2-3, 2002, Pages 107-117

Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents

a ALBERT EINSTEIN COLLEGE OF MEDICINE (United States)

Author keywords

Apoptosis; Autoimmunity; Deoxyguanosine toxicity; Immucillin; Purine nucleoside phosphorylase; T cell leukemia; Transition state

Indexed keywords

DEOXYCYTIDINE; DEOXYGUANOSINE; DEOXYGUANOSINE TRIPHOSPHATE; IMMUCILLIN H; INTERLEUKIN 2; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; AUTOIMMUNE DISEASE; CATALYSIS; DEGRADATION; DISSOCIATION CONSTANT; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SYNTHESIS; GRAFT REJECTION; HUMAN; IMMUNE DEFICIENCY; LYMPHOCYTE PROLIFERATION; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DESIGN; ELECTROSTATICS; ENZYME INHIBITORS; HUMANS; LEUKEMIA, T-CELL; MICE; NUCLEOSIDES; PURINE-NUCLEOSIDE PHOSPHORYLASE; PYRIMIDINONES; PYRROLES; T-LYMPHOCYTES; TRANSPLANTATION, HETEROLOGOUS;

EID: 0037130281 PISSN: 09254439 EISSN: None Source Type: Journal
DOI: 10.1016/S0925-4439(02)00073-X Document Type: Review

Times cited : (88)

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