-
2
-
-
0020597565
-
Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
-
Samuelson, B. 1983. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science (Wash. DC). 220:568-575.
-
(1983)
Science (Wash. DC)
, vol.220
, pp. 568-575
-
-
Samuelson, B.1
-
3
-
-
0019311062
-
Leukotriene B4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
-
Ford-Hutchinson, A.W., M.A. Bray, M.V. Doig, M.E. Shipley, and M.J. Smith. 1980. Leukotriene B4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature (Lond.). 286:264-265.
-
(1980)
Nature (Lond.)
, vol.286
, pp. 264-265
-
-
Ford-Hutchinson, A.W.1
Bray, M.A.2
Doig, M.V.3
Shipley, M.E.4
Smith, M.J.5
-
4
-
-
0019254822
-
Leukotrienes are potent constrictors of human bronchi
-
Dahlen, S.E., P. Hedqvist, S. Hammarstrom, and B. Samuelsson. 1980. Leukotrienes are potent constrictors of human bronchi. Nature (Lond.). 288:484-486.
-
(1980)
Nature (Lond.)
, vol.288
, pp. 484-486
-
-
Dahlen, S.E.1
Hedqvist, P.2
Hammarstrom, S.3
Samuelsson, B.4
-
5
-
-
0005602116
-
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities
-
Rouzer, C.A., T. Matsumoto, and B. Samuelsson. 1986. Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc. Natl. Acad. Sci. USA. 83:857-861.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 857-861
-
-
Rouzer, C.A.1
Matsumoto, T.2
Samuelsson, B.3
-
6
-
-
0027504207
-
5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes
-
Woods, R.J., J.F. Evans, D. Ethier, S. Scott, P.J. Vickers, L. Hearn, J.A. Heibein, S. Charleson, and I.I. Singer. 1993. 5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J. Exp. Med. 178:1935-1946.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1935-1946
-
-
Woods, R.J.1
Evans, J.F.2
Ethier, D.3
Scott, S.4
Vickers, P.J.5
Hearn, L.6
Heibein, J.A.7
Charleson, S.8
Singer, I.I.9
-
7
-
-
0028937635
-
5-lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation
-
Woods, J.W., M.J. Coffey, T.G. Brock, I.I. Singer, and M. Peters-Golden. 1994. 5-lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation. J. Clin. Invest. 95:2035-2046.
-
(1994)
J. Clin. Invest.
, vol.95
, pp. 2035-2046
-
-
Woods, J.W.1
Coffey, M.J.2
Brock, T.G.3
Singer, I.I.4
Peters-Golden, M.5
-
8
-
-
0025021789
-
Identification and isolation of a membrane protein necessary for leukotriene production
-
Miller, D.K., J.W. Gillard, P.J. Vickers, S. Sadowski, C. Leveille, J.A. Mancini, P. Charleson, R.A.F. Dixon, A.W. Ford-Hutchinson, R. Fortin et al. 1990. Identification and isolation of a membrane protein necessary for leukotriene production. Nature (Lond.). 343:278-281.
-
(1990)
Nature (Lond.)
, vol.343
, pp. 278-281
-
-
Miller, D.K.1
Gillard, J.W.2
Vickers, P.J.3
Sadowski, S.4
Leveille, C.5
Mancini, J.A.6
Charleson, P.7
Dixon, R.A.F.8
Ford-Hutchinson, A.W.9
Fortin, R.10
-
9
-
-
0024348059
-
L-663,536 (MK-886), a novel, orally active leukotriene biosynthesis inhibitor
-
Gillard, J., A.W. Ford-Hutchinson, C. Chan, S. Charleson, D. Denis, A. Foster, R. Fortin, S. Leger, C.S. McFarlane, H. Morton et al. 1989. L-663,536 (MK-886), a novel, orally active leukotriene biosynthesis inhibitor. Can. J. Physiol. Pharmacol. 67:456-464.
-
(1989)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 456-464
-
-
Gillard, J.1
Ford-Hutchinson, A.W.2
Chan, C.3
Charleson, S.4
Denis, D.5
Foster, A.6
Fortin, R.7
Leger, S.8
McFarlane, C.S.9
Morton, H.10
-
10
-
-
0025022489
-
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
-
Dixon, R.A.F., R.E. Diehl, E. Opas, E. Rands, P.J. Vickers, J.F. Evans, J.W. Gillard, and D.K. Miller. 1990. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature (Lond.). 343:282-284.
-
(1990)
Nature (Lond.)
, vol.343
, pp. 282-284
-
-
Dixon, R.A.F.1
Diehl, R.E.2
Opas, E.3
Rands, E.4
Vickers, P.J.5
Evans, J.F.6
Gillard, J.W.7
Miller, D.K.8
-
11
-
-
0028172747
-
Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: Implications for biological regulation of 5-lipoxygenase
-
Hatzelmann, A., R. Fruchtmann, K.H. Mohrs, S. Raddatz, M. Matzke, U. Pleiss, J. Keldenich, and R. Muller-Peddinghaus. 1994. Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: implications for biological regulation of 5-lipoxygenase. Agents Actions. 43:64-68.
-
(1994)
Agents Actions
, vol.43
, pp. 64-68
-
-
Hatzelmann, A.1
Fruchtmann, R.2
Mohrs, K.H.3
Raddatz, S.4
Matzke, M.5
Pleiss, U.6
Keldenich, J.7
Muller-Peddinghaus, R.8
-
12
-
-
0029886863
-
Molecular cloning of the gene for human leukotriene C4 synthase
-
Penrose, J.F., J. Spector, M. Baldasaro, K. Xu, J. Boyce, J.P. Arm, K.F. Austen, and B.K. Lam. 1996. Molecular cloning of the gene for human leukotriene C4 synthase. J. Biol. Chem. 271:11356-11361.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11356-11361
-
-
Penrose, J.F.1
Spector, J.2
Baldasaro, M.3
Xu, K.4
Boyce, J.5
Arm, J.P.6
Austen, K.F.7
Lam, B.K.8
-
13
-
-
0028589332
-
Altered inflammatory responses in leukotriene-deficient mice
-
Goulet, J.L., J.N. Snouwaert, A.M. Latour, T.M. Coffman, and B.H. Koller. 1994. Altered inflammatory responses in leukotriene-deficient mice. Proc. Natl. Acad. Sci. USA. 91: 12852-12856.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12852-12856
-
-
Goulet, J.L.1
Snouwaert, J.N.2
Latour, A.M.3
Coffman, T.M.4
Koller, B.H.5
-
14
-
-
0027945466
-
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
-
Chen, X.-S., J.R. Sheller, E.N. Johnson, and C.D. Funk. 1994. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature (Lond.). 372:179-182.
-
(1994)
Nature (Lond.)
, vol.372
, pp. 179-182
-
-
Chen, X.-S.1
Sheller, J.R.2
Johnson, E.N.3
Funk, C.D.4
-
15
-
-
0019512029
-
Type II collagen-induced arthritis. 1. MHC (I-region) linkage and antibody correlates
-
Wooley, P.H., H.S. Luthra, J.M. Stuart, and C.S. David. 1981. Type II collagen-induced arthritis. 1. MHC (I-region) linkage and antibody correlates. J. Exp. Med. 154:688-700.
-
(1981)
J. Exp. Med.
, vol.154
, pp. 688-700
-
-
Wooley, P.H.1
Luthra, H.S.2
Stuart, J.M.3
David, C.S.4
-
16
-
-
0028981040
-
Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis
-
Griffiths, R.J., E.R. Pettipher, K. Koch, C.A. Farrell, R. Breslow, M.J. Conklyn, M.A. Smith, B.C. Hackman, D.J. Wimberly, A.J. Milici et al. 1995. Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis. Proc. Natl. Acad. Sci. USA. 92:517-521.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 517-521
-
-
Griffiths, R.J.1
Pettipher, E.R.2
Koch, K.3
Farrell, C.A.4
Breslow, R.5
Conklyn, M.J.6
Smith, M.A.7
Hackman, B.C.8
Wimberly, D.J.9
Milici, A.J.10
-
17
-
-
0029866858
-
The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation
-
Nickerson-Nutter, C.L., and E.D. Medvedeff. 1996. The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation. Arthritis Rheum. 39:515-521.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 515-521
-
-
Nickerson-Nutter, C.L.1
Medvedeff, E.D.2
-
18
-
-
0024421396
-
Isolation and characterization of biologically active murine interleukin-1 alpha derived from expression of a synthetic gene in Escherichia coli
-
Daumy, G.O., J.M. Merenda, A.S. McColl, G.C. Andrews, A.E. Franke, K.F. Geoghegan, and I.G. Otterness. 1986. Isolation and characterization of biologically active murine interleukin-1 alpha derived from expression of a synthetic gene in Escherichia coli. Biochim. Biophys. Acta. 998:32-42.
-
(1986)
Biochim. Biophys. Acta
, vol.998
, pp. 32-42
-
-
Daumy, G.O.1
Merenda, J.M.2
McColl, A.S.3
Andrews, G.C.4
Franke, A.E.5
Geoghegan, K.F.6
Otterness, I.G.7
-
19
-
-
0027501676
-
Production of chimeras between embryonic stem cells and embryos
-
Stewart, C.L. 1993. Production of chimeras between embryonic stem cells and embryos. Methods Enzymol. 225:823-855.
-
(1993)
Methods Enzymol.
, vol.225
, pp. 823-855
-
-
Stewart, C.L.1
-
20
-
-
0028847175
-
A new embryonic stem cell line from DBA/ 1lacJ mice allows genetic modification in a murine model of human inflammation
-
Roach, M.L., J.L. Stock, R. Byrum, B.H. Koller, and J.D. McNeish. 1995. A new embryonic stem cell line from DBA/ 1lacJ mice allows genetic modification in a murine model of human inflammation. Exp. Cell Res. 221:520-525.
-
(1995)
Exp. Cell Res.
, vol.221
, pp. 520-525
-
-
Roach, M.L.1
Stock, J.L.2
Byrum, R.3
Koller, B.H.4
McNeish, J.D.5
-
21
-
-
0022499792
-
Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products
-
Eskra, J.D., M.J. Pereira, and M.J. Ernest. 1986. Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. Anal. Biochem. 154: 332-337.
-
(1986)
Anal. Biochem.
, vol.154
, pp. 332-337
-
-
Eskra, J.D.1
Pereira, M.J.2
Ernest, M.J.3
-
22
-
-
0023549436
-
Spectrophotometric monitoring of lipoxygenase and cyclooxygenase pathway activity using ionophore stimulated whole blood
-
Sweeney, F., J. Eskra, and T. Carty. 1987. Spectrophotometric monitoring of lipoxygenase and cyclooxygenase pathway activity using ionophore stimulated whole blood. Agents Actions. 21:393-396.
-
(1987)
Agents Actions
, vol.21
, pp. 393-396
-
-
Sweeney, F.1
Eskra, J.2
Carty, T.3
-
23
-
-
24544436972
-
A universal automated method for solid-phase extraction, HPLC, and fractionation of biological fluids for drug level and eicosanoid quantitation by UV detection and enzyme immunoassay
-
Wright, C., and J. Eskra. 1993. A universal automated method for solid-phase extraction, HPLC, and fractionation of biological fluids for drug level and eicosanoid quantitation by UV detection and enzyme immunoassay. Pharmaceutical Res. 10(Suppl.):S-57.
-
(1993)
Pharmaceutical Res.
, vol.10
, Issue.SUPPL.
-
-
Wright, C.1
Eskra, J.2
-
24
-
-
0023675940
-
In vivo administration with IL-1 accelerates the development of collagen-induced arthritis in mice
-
Hom, J.T., A.M. Bendele, and D.G. Carlson. 1988. In vivo administration with IL-1 accelerates the development of collagen-induced arthritis in mice. J. Immunol. 141:834-841.
-
(1988)
J. Immunol.
, vol.141
, pp. 834-841
-
-
Hom, J.T.1
Bendele, A.M.2
Carlson, D.G.3
-
25
-
-
0024543692
-
Interleukin-1 potentiates the development of collagen-induced arthritis in mice
-
Killar, L.M., and C.J. Dunn. 1989. Interleukin-1 potentiates the development of collagen-induced arthritis in mice. Clin. Sci. 76:535-538.
-
(1989)
Clin. Sci.
, vol.76
, pp. 535-538
-
-
Killar, L.M.1
Dunn, C.J.2
-
26
-
-
0026096856
-
A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the knee joint and peritoneal cavity
-
Griffiths, R.J., S.W. Li, B.E. Wood, and A. Blackham. 1991. A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the knee joint and peritoneal cavity. Agents Actions. 32:312-320.
-
(1991)
Agents Actions
, vol.32
, pp. 312-320
-
-
Griffiths, R.J.1
Li, S.W.2
Wood, B.E.3
Blackham, A.4
-
27
-
-
0023144327
-
Activation of leukocyte movement and displacement of leukotriene B4 from leukocyte membrane preparations by (12R)- And (12S)-hydroxyeicosatetraenoic acid
-
Evans, J.F., Y. Leblanc, B.J. Fitzsimmons, S. Charleson, D. Nathaniel, and C. Leveille. 1987. Activation of leukocyte movement and displacement of leukotriene B4 from leukocyte membrane preparations by (12R)-and (12S)-hydroxyeicosatetraenoic acid. Biochim. Biophys. Acta. 917:406-410.
-
(1987)
Biochim. Biophys. Acta
, vol.917
, pp. 406-410
-
-
Evans, J.F.1
Leblanc, Y.2
Fitzsimmons, B.J.3
Charleson, S.4
Nathaniel, D.5
Leveille, C.6
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