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Volumn 16, Issue 6, 1997, Pages 1351-1359

The role of the PH domain in the signal-dependent membrane targeting of Sos

Author keywords

Leading edge; Lipids; PH domains; Ras; Sos

Indexed keywords

PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PLECKSTRIN; RAS PROTEIN; RECOMBINANT PROTEIN;

EID: 0031002348     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.6.1351     Document Type: Article
Times cited : (117)

References (44)
  • 1
    • 0027931640 scopus 로고
    • Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
    • Aronheim, A.D., Engelberg, D., Li, N., al-Alawi, N., Schlessinger, J. and Karin, M. (1994) Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell, 78, 949-961.
    • (1994) Cell , vol.78 , pp. 949-961
    • Aronheim, A.D.1    Engelberg, D.2    Li, N.3    Al-Alawi, N.4    Schlessinger, J.5    Karin, M.6
  • 2
    • 0029040133 scopus 로고
    • The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor
    • Batzer, A.G., Blaikie, P., Nelson, K., Schlessinger, J. and Margolis, B. (1995) The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor. Mol. Cell. Biol., 15, 4403-4409.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4403-4409
    • Batzer, A.G.1    Blaikie, P.2    Nelson, K.3    Schlessinger, J.4    Margolis, B.5
  • 3
    • 0029640799 scopus 로고
    • A phosphotyrosine interaction domain
    • Bork, P. and Margolis, B. (1995) A phosphotyrosine interaction domain. Cell, 80, 693-694.
    • (1995) Cell , vol.80 , pp. 693-694
    • Bork, P.1    Margolis, B.2
  • 4
    • 0029742101 scopus 로고    scopus 로고
    • The N terminal pleckstrin, coiled-coil and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium
    • Buchsbaum, R., Telliez, J.-B., Goonesekera, S. and Feig, L. (1996) The N terminal pleckstrin, coiled-coil and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium. Mol. Cell. Biol., 16, 4888-1896.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4888-11896
    • Buchsbaum, R.1    Telliez, J.-B.2    Goonesekera, S.3    Feig, L.4
  • 5
    • 0027153103 scopus 로고
    • ras through the formation of a complex receptor, Grb2 adaptor protein and Sos nucleotide exchange factor
    • ras through the formation of a complex receptor, Grb2 adaptor protein and Sos nucleotide exchange factor. Cell, 48, 611-620.
    • (1993) Cell , vol.48 , pp. 611-620
    • Buday, L.1    Downward, J.2
  • 7
    • 0028040136 scopus 로고
    • D-myo-inositol 1,4,5-triphosphate inhibits binding of phospholipase C-δ1 to bilayer membranes
    • Cifuentes, M.E., Delaney, T. and Rebecchi, M.J. (1994) D-myo-inositol 1,4,5-triphosphate inhibits binding of phospholipase C-δ1 to bilayer membranes. J. Biol. Chem., 269, 1945-1948.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1945-1948
    • Cifuentes, M.E.1    Delaney, T.2    Rebecchi, M.J.3
  • 9
    • 0030010590 scopus 로고    scopus 로고
    • Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
    • Eck, M.J. Dhe-Paganon, S., Trub, T., Nolte, R.T. and Shoelson, S.E. (1996) Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor. Cell, 85, 695-705.
    • (1996) Cell , vol.85 , pp. 695-705
    • Eck, M.J.1    Dhe-Paganon, S.2    Trub, T.3    Nolte, R.T.4    Shoelson, S.E.5
  • 10
    • 0027910431 scopus 로고
    • Association of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
    • Egan, S.E., Giddings, B.W., Brooks, M.W., Buday, L., Sizeland, A.M. and Weinberg, R. (1993) Association of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 363, 45-51.
    • (1993) Nature , vol.363 , pp. 45-51
    • Egan, S.E.1    Giddings, B.W.2    Brooks, M.W.3    Buday, L.4    Sizeland, A.M.5    Weinberg, R.6
  • 11
    • 0029617615 scopus 로고
    • Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
    • Ferguson, K.M., Lemmon, M.A., Schlessinger, J. and Sigler, P. (1995) Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell, 83, 1037-1046.
    • (1995) Cell , vol.83 , pp. 1037-1046
    • Ferguson, K.M.1    Lemmon, M.A.2    Schlessinger, J.3    Sigler, P.4
  • 12
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T.F., Yang, S.-I., Chan, T.O., Datta, K., Kazlauskas, A., Morrison, D.K., Kaplan, D.R. and Tsichlis, P.N. (1995) The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell, 81, 727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.-I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 14
    • 0028021882 scopus 로고
    • Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
    • Harlan, J.E., Hajduk, P.J., Yoon, H.S. and Fesik, S.W. (1994) Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature, 371, 168-170.
    • (1994) Nature , vol.371 , pp. 168-170
    • Harlan, J.E.1    Hajduk, P.J.2    Yoon, H.S.3    Fesik, S.W.4
  • 17
    • 0028670203 scopus 로고
    • The pleckstrin homolog domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta
    • Konishi, H., Kuroda, S. and Kikkawa, U. (1994) The pleckstrin homolog domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta. Biochem. Biophys. Res. Commun., 205, 1770-1775.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1770-1775
    • Konishi, H.1    Kuroda, S.2    Kikkawa, U.3
  • 18
    • 0028874438 scopus 로고
    • Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
    • Lemmon, M.A., Ferguson, K.M., Sigler, P.B. and Schlessinger, J. (1995) Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proc. Natl Acad. Sci. USA, 92, 10472-10476.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 10472-10476
    • Lemmon, M.A.1    Ferguson, K.M.2    Sigler, P.B.3    Schlessinger, J.4
  • 19
    • 0029939448 scopus 로고    scopus 로고
    • PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface
    • Lemmon, M.A., Ferguson, K.M. and Schlessinger, J. (1996) PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell, 85, 621-624.
    • (1996) Cell , vol.85 , pp. 621-624
    • Lemmon, M.A.1    Ferguson, K.M.2    Schlessinger, J.3
  • 20
    • 0027312272 scopus 로고
    • Guanine-nucleotide-releasing factor hSos 1 binds to Grb2 and links receptor tyrosine kinases to ras signaling
    • Li., N., Batzer, A., Daly, R., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B. and Schlessinger, J. (1993) Guanine-nucleotide-releasing factor hSos 1 binds to Grb2 and links receptor tyrosine kinases to ras signaling. Nature, 363, 85-88.
    • (1993) Nature , vol.363 , pp. 85-88
    • Li, N.1    Batzer, A.2    Daly, R.3    Yajnik, V.4    Skolnik, E.5    Chardin, P.6    Bar-Sagi, D.7    Margolis, B.8    Schlessinger, J.9
  • 21
    • 0029029153 scopus 로고
    • Functional roles for the pleckstrin and Db1 homology regions in the Ras exchange factor Son of sevenless
    • McCollam, L., Bonfini, L., Karlovich, C.A., Conway, B.R., Kozma, L.M., Banerjee, U. and Czech, M.P. (1995) Functional roles for the pleckstrin and Db1 homology regions in the Ras exchange factor Son of sevenless. J. Biol. Chem., 270, 15954-15957.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15954-15957
    • McCollam, L.1    Bonfini, L.2    Karlovich, C.A.3    Conway, B.R.4    Kozma, L.M.5    Banerjee, U.6    Czech, M.P.7
  • 22
    • 0027212082 scopus 로고
    • Signal transduction. How receptors turn Ras on
    • McCormick, F. (1993) Signal transduction. How receptors turn Ras on. Nature, 363, 15-16.
    • (1993) Nature , vol.363 , pp. 15-16
    • McCormick, F.1
  • 23
    • 0027183541 scopus 로고
    • The PH domain: A common piece in the structural patchwork of signalling proteins
    • Musacchio, A., Gibson, T., Rice, P. Thompson, J. and Saraste, M. (1993) The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem. Sci., 18, 343-348.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 343-348
    • Musacchio, A.1    Gibson, T.2    Rice, P.3    Thompson, J.4    Saraste, M.5
  • 25
    • 0027468233 scopus 로고
    • A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange
    • Olivier, J.P. Raabe, T., Henkemayer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, J., Hafen, E. and Pawson, T. (1993) A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange. Sos. Cell, 73, 179-191.
    • (1993) Sos. Cell , vol.73 , pp. 179-191
    • Olivier, J.P.1    Raabe, T.2    Henkemayer, M.3    Dickson, B.4    Mbamalu, G.5    Margolis, B.6    Schlessinger, J.7    Hafen, E.8    Pawson, T.9
  • 26
  • 27
    • 0029039613 scopus 로고
    • Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with GßY subunits and lipid
    • Pitcher, J.A., Touhara, K., Payne, E.S. and Lefkowitz, R.J. (1995) Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with GßY subunits and lipid. J. Biol. Chem., 270, 11707-11710.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11707-11710
    • Pitcher, J.A.1    Touhara, K.2    Payne, E.S.3    Lefkowitz, R.J.4
  • 28
    • 0027999033 scopus 로고
    • Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity
    • Quilliam, L.A., Huff, S.Y., Rabun, K.M., Wei, W., Park, W., Broek, D. and Der, C.J. (1994) Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proc. Natl Acad. Sci. USA, 91, 8512-8516.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8512-8516
    • Quilliam, L.A.1    Huff, S.Y.2    Rabun, K.M.3    Wei, W.4    Park, W.5    Broek, D.6    Der, C.J.7
  • 29
    • 0027305921 scopus 로고
    • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
    • Rawlings, D.J. et al. (1993) Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science. 260, 358-361.
    • (1993) Science , vol.260 , pp. 358-361
    • Rawlings, D.J.1
  • 30
    • 0027050183 scopus 로고
    • Phosphoinositide-specific phospholipase C-51 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-biphosphate
    • Rebecchi, M., Peterson, A. and McLaughlin, S. (1992) Phosphoinositide-specific phospholipase C-51 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-biphosphate. Biochemistry, 31, 12742-12747.
    • (1992) Biochemistry , vol.31 , pp. 12742-12747
    • Rebecchi, M.1    Peterson, A.2    McLaughlin, S.3
  • 31
    • 0026462867 scopus 로고
    • Dynamics of beta 1 integrin-mediated adhesive contacts in motile fibroblasts
    • Regen, C.M. and Horwitz, A.F. (1992) Dynamics of beta 1 integrin-mediated adhesive contacts in motile fibroblasts. J. Cell Biol. 119, 1347-1359.
    • (1992) J. Cell Biol. , vol.119 , pp. 1347-1359
    • Regen, C.M.1    Horwitz, A.F.2
  • 32
    • 0030040967 scopus 로고
    • The pleckstrin homology domain: An intriguing multifunctional protein module
    • Shaw, G. (1995) The pleckstrin homology domain: an intriguing multifunctional protein module. BioEssays, 18, 35-46.
    • (1995) BioEssays , vol.18 , pp. 35-46
    • Shaw, G.1
  • 33
    • 0027261447 scopus 로고
    • Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes
    • Thomas, J.D., Sideras, P., Smith, C.I.E., Vorechovsky, I., Chapman, V. and Paul, W.E. (1993) Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science, 261, 355-358.
    • (1993) Science , vol.261 , pp. 355-358
    • Thomas, J.D.1    Sideras, P.2    Smith, C.I.E.3    Vorechovsky, I.4    Chapman, V.5    Paul, W.E.6
  • 35
    • 0029029892 scopus 로고
    • Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region
    • Voliovitch, H., Schindler, D.G., Hadari, Y.R., Taylor, S.I., Accili, D. and Zick, Y. (1995) Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region. J. Biol. Chem., 270, 18083-18087.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18083-18087
    • Voliovitch, H.1    Schindler, D.G.2    Hadari, Y.R.3    Taylor, S.I.4    Accili, D.5    Zick, Y.6
  • 36
    • 0029031112 scopus 로고
    • The Grb2 binding domain of mSos1 is not required for downstream signal transduction
    • Wang, W., Fisher, E.M.C., Jia, Q., Dum, J.M., Porfiri, E., Downward, J. and Egan, S.E. (1995) The Grb2 binding domain of mSos1 is not required for downstream signal transduction. Nature Genet., 10, 294-300.
    • (1995) Nature Genet. , vol.10 , pp. 294-300
    • Wang, W.1    Fisher, E.M.C.2    Jia, Q.3    Dum, J.M.4    Porfiri, E.5    Downward, J.6    Egan, S.E.7
  • 38
    • 0017647917 scopus 로고
    • Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells
    • Wigler, M., Silverstein, S., Lee, L.S., Pellicer, A., Cheng, Y.C. and Axel, R. (1977) Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell, 11, 223-227.
    • (1977) Cell , vol.11 , pp. 223-227
    • Wigler, M.1    Silverstein, S.2    Lee, L.S.3    Pellicer, A.4    Cheng, Y.C.5    Axel, R.6
  • 39
    • 0028132554 scopus 로고
    • Expression and characterization of an inositol 1,4,5-tnsphosphate binding domain of phosphatidylinositol-specific phospholipase Cδ1
    • Yagisawa, H. et al. (1994) Expression and characterization of an inositol 1,4,5-tnsphosphate binding domain of phosphatidylinositol-specific phospholipase Cδ1. J. Biol. Chem., 269, 20179-20188.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20179-20188
    • Yagisawa, H.1
  • 40
    • 0030058206 scopus 로고    scopus 로고
    • Identification of residues within the SHC phosphotyrosine binding/phosphotyrosine interaction domain crucial for phosphopeptide interaction
    • Yajnik, V., Blaikie, P., Bork, P. and Margolis, B. (1996) Identification of residues within the SHC phosphotyrosine binding/phosphotyrosine interaction domain crucial for phosphopeptide interaction. J. Biol Chem., 271, 1813-1816.
    • (1996) J. Biol Chem. , vol.271 , pp. 1813-1816
    • Yajnik, V.1    Blaikie, P.2    Bork, P.3    Margolis, B.4
  • 41
    • 0028564915 scopus 로고
    • The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C
    • Yao, L., Kawakami, Y. and Kawakami, T. (1994) The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc. Natl Acad. Sci. USA, 91, 9175-9179.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 9175-9179
    • Yao, L.1    Kawakami, Y.2    Kawakami, T.3
  • 42
    • 0029978885 scopus 로고    scopus 로고
    • Identification of the binding site for acidic phospholipids on the PH domain of dynamin: Implications for stimulation of GTPase activity
    • Zheng, J., Cahill, S., Lemmon, M.A., Fushman, D., Schlessinger, J. and Cowburn, D. (1996a) Identification of the binding site for acidic phospholipids on the PH domain of dynamin: implications for stimulation of GTPase activity. J. Mol. Biol., 255, 14-21.
    • (1996) J. Mol. Biol. , vol.255 , pp. 14-21
    • Zheng, J.1    Cahill, S.2    Lemmon, M.A.3    Fushman, D.4    Schlessinger, J.5    Cowburn, D.6
  • 43
    • 0029783037 scopus 로고    scopus 로고
    • The pleckstrin homology domain mediates transformation by oncogenic Db1 through specific intracellular targeting
    • Zheng, Y., Zangrilli, D., Cerione, R.A. and Eva, A. (1996b) The pleckstrin homology domain mediates transformation by oncogenic Db1 through specific intracellular targeting. J. Biol. Chem., 271, 19017-19020.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19017-19020
    • Zheng, Y.1    Zangrilli, D.2    Cerione, R.A.3    Eva, A.4
  • 44
    • 0028860968 scopus 로고
    • Structure and ligand recognition of the phosphotyrosine binding domain of She
    • Zhou, M.-M. et al. (1995) Structure and ligand recognition of the phosphotyrosine binding domain of She. Nature. 378, 584-592.
    • (1995) Nature , vol.378 , pp. 584-592
    • Zhou, M.-M.1


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