-
1
-
-
0024463389
-
Genetic analysis of mammalian GAP expressed in yeast
-
Ballester, R., T. Michaeli, K. Ferguson, H.-P. Xu, F. McCormick, and M. Wigler. 1989. Genetic analysis of mammalian GAP expressed in yeast. Cell 59:681-686.
-
(1989)
Cell
, vol.59
, pp. 681-686
-
-
Ballester, R.1
Michaeli, T.2
Ferguson, K.3
Xu, H.-P.4
McCormick, F.5
Wigler, M.6
-
2
-
-
0026011490
-
Mutational analysis of the putative effector domain of the GTP-binding YPT1 protein in yeast suggests specific regulation by a novel GAP activity
-
Becker, J., T. J. Tan, H.-H. Trepte, and D. Gallwitz. 1991: Mutational analysis of the putative effector domain of the GTP-binding YPT1 protein in yeast suggests specific regulation by a novel GAP activity. EMBO J. 10:785-792.
-
(1991)
EMBO J.
, vol.10
, pp. 785-792
-
-
Becker, J.1
Tan, T.J.2
Trepte, H.-H.3
Gallwitz, D.4
-
3
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
Boguski, M. S., and F. McCormick. 1993. Proteins regulating Ras and its relatives. Nature 366:643-654.
-
(1993)
Nature
, vol.366
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
4
-
-
0027232605
-
Emerging concepts in the Ras superfamily of GTP-binding proteins
-
Bokoch, G. M., and C. J. Der. 1993. Emerging concepts in the Ras superfamily of GTP-binding proteins. FASEB J. 7:750-759.
-
(1993)
FASEB J.
, vol.7
, pp. 750-759
-
-
Bokoch, G.M.1
Der, C.J.2
-
5
-
-
0032560850
-
The structural basis of the activation of Ras by Sos
-
Boriack-Sjodin, P. A., M. Margarit, D. Bar-Sagi, and J. Kuriyan. 1998. The structural basis of the activation of Ras by Sos. Nature (London) 394:337-343.
-
(1998)
Nature (London)
, vol.394
, pp. 337-343
-
-
Boriack-Sjodin, P.A.1
Margarit, M.2
Bar-Sagi, D.3
Kuriyan, J.4
-
6
-
-
0026026818
-
The GTPase superfamily: Conserved structure and molecular mechanism
-
Bourne, H. R., D. A. Sanders, and F. McCormick. 1991. The GTPase superfamily: conserved structure and molecular mechanism. Nature 349:117-127.
-
(1991)
Nature
, vol.349
, pp. 117-127
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
7
-
-
0023652371
-
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway
-
Broek, D., T. Toda, T. Michaili, L. Levin, C. Birchmeier, M. Zollar, S. Powers, and M. Wigler. 1987. The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell 48:789-799.
-
(1987)
Cell
, vol.48
, pp. 789-799
-
-
Broek, D.1
Toda, T.2
Michaili, T.3
Levin, L.4
Birchmeier, C.5
Zollar, M.6
Powers, S.7
Wigler, M.8
-
9
-
-
0026463861
-
Amino acid residues in the ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A
-
Burstein, E. S., W. H. Brondyk, and I. G. Macara. 1992. Amino acid residues in the ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A. J. Biol. Chem. 267:22715-22718.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22715-22718
-
-
Burstein, E.S.1
Brondyk, W.H.2
Macara, I.G.3
-
10
-
-
0027417269
-
A mammalian guanine nucleotide releasing protein enhances function of yeast secretory protein Sec4
-
Burton, J. L., D. Roberts, M. Montaldi, P. Novick, and P. DeCamilli. 1993. A mammalian guanine nucleotide releasing protein enhances function of yeast secretory protein Sec4. Nature 361:464-467.
-
(1993)
Nature
, vol.361
, pp. 464-467
-
-
Burton, J.L.1
Roberts, D.2
Montaldi, M.3
Novick, P.4
DeCamilli, P.5
-
11
-
-
0031021685
-
An evolutionary conserved domain in a subfamily of Rabs is crucial for the interaction with the guanyl nucleotide exchange factor Mss4
-
Burton, J. L., V. Slepnev, and P. V. De Camilli. 1997. An evolutionary conserved domain in a subfamily of Rabs is crucial for the interaction with the guanyl nucleotide exchange factor Mss4. J. Biol. Chem. 272:3663-3668.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3663-3668
-
-
Burton, J.L.1
Slepnev, V.2
De Camilli, P.V.3
-
12
-
-
0001766152
-
Structural conservation of ras-related proteins and its functional implications
-
F. D. Burton and B. Lutz (ed.), Spring-Verlag KG, Berlin, Germany
-
Chardin, D. 1993. Structural conservation of ras-related proteins and its functional implications, p. 159-176. In F. D. Burton and B. Lutz (ed.), GTPases in biology I, vol. 108. Spring-Verlag KG, Berlin, Germany.
-
(1993)
GTPases in Biology I
, vol.108
, pp. 159-176
-
-
Chardin, D.1
-
13
-
-
0027215522
-
RAG-2-deficient blastocyst complementation: An assay of gene function in lymphocyte development
-
Chen, J., R. Lansford, V. Stewart, F. Young, and F. W. Alt. 1993. RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc. Natl. Acad. Sci. USA 90:4528-4532.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4528-4532
-
-
Chen, J.1
Lansford, R.2
Stewart, V.3
Young, F.4
Alt, F.W.5
-
14
-
-
0028122478
-
Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor
-
Chen, S. Y., S. Y. Huff, C. C. Lai, C. J. Der, and S. Powers. 1994. Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor. Oncogene 9:2691-2698.
-
(1994)
Oncogene
, vol.9
, pp. 2691-2698
-
-
Chen, S.Y.1
Huff, S.Y.2
Lai, C.C.3
Der, C.J.4
Powers, S.5
-
16
-
-
0030054980
-
Distal switch II region of Ras2p is required for interaction with guanine nucleotide exchange factor
-
Crechet, J.-B., A. Bernardi, and A. Parmeggiani. 1996. Distal switch II region of Ras2p is required for interaction with guanine nucleotide exchange factor. J. Biol. Chem. 271:17234-17240.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17234-17240
-
-
Crechet, J.-B.1
Bernardi, A.2
Parmeggiani, A.3
-
17
-
-
85038544895
-
-
Day, G.-J., and D. Broek. Unpublished results
-
Day, G.-J., and D. Broek. Unpublished results.
-
-
-
-
18
-
-
13144250140
-
The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways
-
Fan, W.-T., A. Koch, C. L. de Hoog, N. P. Fam, and M. F. Moran. 1998. The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways. Curr. Biol. 8:935-938.
-
(1998)
Curr. Biol.
, vol.8
, pp. 935-938
-
-
Fan, W.-T.1
Koch, A.2
De Hoog, C.L.3
Fam, N.P.4
Moran, M.F.5
-
19
-
-
0028216328
-
Guanine-nucleotide exchange factors: A family of positive regulators of Ras and related GTPases
-
Feig, L. A. 1994. Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases. Curr. Opin. Cell Biol. 6:204-211.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 204-211
-
-
Feig, L.A.1
-
20
-
-
0023715225
-
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
-
Feig, L. A., and G. M. Cooper. 1988. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8:3235-3243.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3235-3243
-
-
Feig, L.A.1
Cooper, G.M.2
-
21
-
-
0031582212
-
Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain
-
Freshney, N. W., S. D. Goonesekera, and L. A. Feig. 1997. Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain. FEBS Lett. 407:111-115.
-
(1997)
FEBS Lett.
, vol.407
, pp. 111-115
-
-
Freshney, N.W.1
Goonesekera, S.D.2
Feig, L.A.3
-
22
-
-
0021015541
-
A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product
-
Gallwitz, D., C. Donath, and C. Sander. 1983. A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product. Nature (London) 306:704-707.
-
(1983)
Nature (London)
, vol.306
, pp. 704-707
-
-
Gallwitz, D.1
Donath, C.2
Sander, C.3
-
23
-
-
0024336096
-
The ras oncogene - An important regulatory element in lower eucaryotic organisms
-
Gibbs, J. B., and M. S. Marshall. 1989. The ras oncogene - an important regulatory element in lower eucaryotic organisms. Microbiol. Rev. 53:171-185.
-
(1989)
Microbiol. Rev.
, vol.53
, pp. 171-185
-
-
Gibbs, J.B.1
Marshall, M.S.2
-
24
-
-
3643144757
-
-
Personal communication
-
Goldberg, J. 1998. Personal communication.
-
(1998)
-
-
Goldberg, J.1
-
25
-
-
0027587322
-
Ras-related proteins
-
Hall, A. 1993. Ras-related proteins. Curr. Opin. Cell Biol. 5:265-268.
-
(1993)
Curr. Opin. Cell Biol.
, vol.5
, pp. 265-268
-
-
Hall, A.1
-
26
-
-
0031034050
-
Lck regulates Vav activation of members of the Rho family of GTPases
-
Han, J., B. Das, W. Wei, L. Van Aelst, R. D. Mosteller, R. Khosravi-Far, J. K. Westwick, C. J. Der, and D. Broek. 1997. Lck regulates Vav activation of members of the Rho family of GTPases. Mol. Cell. Biol. 17:1346-1353.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1346-1353
-
-
Han, J.1
Das, B.2
Wei, W.3
Van Aelst, L.4
Mosteller, R.D.5
Khosravi-Far, R.6
Westwick, J.K.7
Der, C.J.8
Broek, D.9
-
27
-
-
3643089568
-
-
Personal communication
-
Han, J., and D. Broek. 1998. Personal communication.
-
(1998)
-
-
Han, J.1
Broek, D.2
-
28
-
-
0028365073
-
Cdc25p, the guanine nucleotide exchange factor for the Ras proteins of Saccharomyces cerevisiae, promotes exchange by stabilizing Ras in a nucleotide-free state
-
Haney, S. A., and J. R. Broach. 1994. Cdc25p, the guanine nucleotide exchange factor for the Ras proteins of Saccharomyces cerevisiae, promotes exchange by stabilizing Ras in a nucleotide-free state. J. Biol. Chem. 269: 16541-16548.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16541-16548
-
-
Haney, S.A.1
Broach, J.R.2
-
29
-
-
0023661362
-
The ras-related ypt protein is an ubiquitous eukaryotic protein: Isolation and sequence analysis of mouse DNA highly homologous to the yeast YPT1 gene
-
Haubruck, H., C. Disela, P. Wagner, and D. Gallwitz. 1987. The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse DNA highly homologous to the yeast YPT1 gene. EMBO J. 6:4049-4053.
-
(1987)
EMBO J.
, vol.6
, pp. 4049-4053
-
-
Haubruck, H.1
Disela, C.2
Wagner, P.3
Gallwitz, D.4
-
30
-
-
17344377424
-
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
-
Horiuchi, H., R. Lippe, H. M. McBride, M. Rubino, P. Woodman, H. Stenmark, V. Rybin, M. Wilm, K. Ashman, M. Mann, and M. Zerial. 1997. A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 90:1149-1159.
-
(1997)
Cell
, vol.90
, pp. 1149-1159
-
-
Horiuchi, H.1
Lippe, R.2
McBride, H.M.3
Rubino, M.4
Woodman, P.5
Stenmark, H.6
Rybin, V.7
Wilm, M.8
Ashman, K.9
Mann, M.10
Zerial, M.11
-
31
-
-
0020529962
-
Transformation of intact yeast cells treated with alkali cations
-
Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163-168.
-
(1983)
J. Bacteriol.
, vol.153
, pp. 163-168
-
-
Ito, H.1
Fukuda, Y.2
Murata, K.3
Kimura, A.4
-
32
-
-
0028820010
-
The YPT1 GTPase is essential for the first two steps of the yeast secretory pathway
-
Jedd, G., C. Richardson, R. Litt, and N. Segev. 1995. The YPT1 GTPase is essential for the first two steps of the yeast secretory pathway. J. Cell Biol. 131:583-590.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 583-590
-
-
Jedd, G.1
Richardson, C.2
Litt, R.3
Segev, N.4
-
33
-
-
0029098572
-
Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport
-
Jones, S., R. J. Litt, C. J. Richardson, and N. Segev. 1995. Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport. J. Cell Biol. 130:1051-1061.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 1051-1061
-
-
Jones, S.1
Litt, R.J.2
Richardson, C.J.3
Segev, N.4
-
34
-
-
0028287285
-
Two types of RAS mutants that dominantly interfere with activators of RAS
-
Jung, V., W. Wei, R. Ballester, J. Camonis, S. Mi, L. Van Aelst, M. Wigler, and D. Broek. 1994. Two types of RAS mutants that dominantly interfere with activators of RAS. Mol. Cell. Biol. 14:3707-3718.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3707-3718
-
-
Jung, V.1
Wei, W.2
Ballester, R.3
Camonis, J.4
Mi, S.5
Van Aelst, L.6
Wigler, M.7
Broek, D.8
-
35
-
-
0029890896
-
Oncogenic Ras activation of Raf/mitogen-aetivated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
Khosravi-Far, R., M. A. White, J. K. Westwick, P. A. Solski, M. Chrzanowska-Wodnicka, L. Van Aelst, M. H. Wigler, and C. J. Der. 1996. Oncogenic Ras activation of Raf/mitogen-aetivated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol. Cell. Biol. 16:3923-3933.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowska-Wodnicka, M.5
Van Aelst, L.6
Wigler, M.H.7
Der, C.J.8
-
36
-
-
0025193871
-
Three-dimensional structures of H-ras p21 mutants: Molecular bases for their inability to function as signal switch molecules
-
Krengel, U., L. Schlichting, A. Scherer, R. Shumann, M. Frech, J. John, W. Kabsch, E. F. Pai, and A. Wittinghofer. 1990. Three-dimensional structures of H-ras p21 mutants: molecular bases for their inability to function as signal switch molecules. Cell 62:539-548.
-
(1990)
Cell
, vol.62
, pp. 539-548
-
-
Krengel, U.1
Schlichting, L.2
Scherer, A.3
Shumann, R.4
Frech, M.5
John, J.6
Kabsch, W.7
Pai, E.F.8
Wittinghofer, A.9
-
37
-
-
0027502176
-
Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins
-
Lai, C.-C., M. Boguski, D. Broek, and S. Powers. 1993. Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol. Cell. Biol. 13:1345-1352.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1345-1352
-
-
Lai, C.-C.1
Boguski, M.2
Broek, D.3
Powers, S.4
-
38
-
-
0029838770
-
Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release
-
Leonardsen, L., J. E. DeClue, H. Lybaek, D. R. Lowy, and B. M. Willumsen. 1996. Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release. Oncogene 13:2177-2187.
-
(1996)
Oncogene
, vol.13
, pp. 2177-2187
-
-
Leonardsen, L.1
DeClue, J.E.2
Lybaek, H.3
Lowy, D.R.4
Willumsen, B.M.5
-
39
-
-
0030462224
-
Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization
-
Lounsbury, K. M., S. A. Richards, K. L. Carey, and I. G. Macara. 1996. Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization. J. Biol. Chem. 271:32834-32841.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32834-32841
-
-
Lounsbury, K.M.1
Richards, S.A.2
Carey, K.L.3
Macara, I.G.4
-
41
-
-
0029985757
-
The ras superfamily of GTPases
-
Macara, I. G., K. M. Lounsbury, S. A. Richards, C. McKiernan, and D. Bar-Sagi. 1996. The ras superfamily of GTPases. FASEB J. 10:625-630.
-
(1996)
FASEB J.
, vol.10
, pp. 625-630
-
-
Macara, I.G.1
Lounsbury, K.M.2
Richards, S.A.3
McKiernan, C.4
Bar-Sagi, D.5
-
43
-
-
0027404270
-
Characterization of ras effector mutant interactions with the NF1-GAP related domain
-
Marshall, M. S., and L. A. Hettich. 1993. Characterization of ras effector mutant interactions with the NF1-GAP related domain. Oncogene 8:425-431.
-
(1993)
Oncogene
, vol.8
, pp. 425-431
-
-
Marshall, M.S.1
Hettich, L.A.2
-
44
-
-
0028137615
-
Activators and effectors of ras p21 proteins
-
McCormick, F. 1994. Activators and effectors of ras p21 proteins. Curr. Opin. Genet. Dev. 4:71-76.
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, pp. 71-76
-
-
McCormick, F.1
-
45
-
-
0026371984
-
Regulation of ras p21 by GTPase activating proteins
-
McCormick, F., G. A. Martin, R. Clark, G. Bollag, and P. Polakis. 1991. Regulation of ras p21 by GTPase activating proteins. Cold Spring Harbor Symp. Quant. Biol. 56:237-241.
-
(1991)
Cold Spring Harbor Symp. Quant. Biol.
, vol.56
, pp. 237-241
-
-
McCormick, F.1
Martin, G.A.2
Clark, R.3
Bollag, G.4
Polakis, P.5
-
46
-
-
0028518520
-
Phenotype of the fission yeast cell cycle regulatory mutant pim 1-46 is suppressed by a tobacco cDNA encoding a small, Ran-like GTP-binding protein
-
Merkle, T., T. Haizel, T. Matsumoto, K. Harter, G. Dallmann, and F. Nagy. 1994. Phenotype of the fission yeast cell cycle regulatory mutant pim 1-46 is suppressed by a tobacco cDNA encoding a small, Ran-like GTP-binding protein. Plant J. 6:555-565.
-
(1994)
Plant J.
, vol.6
, pp. 555-565
-
-
Merkle, T.1
Haizel, T.2
Matsumoto, T.3
Harter, K.4
Dallmann, G.5
Nagy, F.6
-
47
-
-
0026632813
-
Mutations of Ha-ras p21 that define important regions for guanine nucleotide dissociation stimulator
-
Mistou, M. Y., E. Jacquet, P. Poullet, H. Rensland, P. Gideon, I. Schlichting, A. Wittinghofer, and A. Parmeggiani. 1992. Mutations of Ha-ras p21 that define important regions for guanine nucleotide dissociation stimulator. EMBO J. 11:2391-2397.
-
(1992)
EMBO J.
, vol.11
, pp. 2391-2397
-
-
Mistou, M.Y.1
Jacquet, E.2
Poullet, P.3
Rensland, H.4
Gideon, P.5
Schlichting, I.6
Wittinghofer, A.7
Parmeggiani, A.8
-
48
-
-
0032488847
-
Structure of the guanine nucleotide exchange factor Sec7 domain of human Aron and analysis of the interaction with ARF GTPase
-
Mossessova, E., J. M. Gulbis, and J. Goldberg. 1998. Structure of the guanine nucleotide exchange factor Sec7 domain of human Aron and analysis of the interaction with ARF GTPase. Cell 92:415-423.
-
(1998)
Cell
, vol.92
, pp. 415-423
-
-
Mossessova, E.1
Gulbis, J.M.2
Goldberg, J.3
-
49
-
-
0028178179
-
Identification of residues of the H-Ras protein critical for functional interaction with guanine nucleotide exchange factors
-
Mosteller, R. D., J. Han, and D. Broek. 1994. Identification of residues of the H-Ras protein critical for functional interaction with guanine nucleotide exchange factors. Mol. Cell. Biol. 14:1104-1112.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1104-1112
-
-
Mosteller, R.D.1
Han, J.2
Broek, D.3
-
50
-
-
0027401746
-
DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function
-
Moya, M., D. Roberts, and P. Novick. 1993. DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function. Nature 361:460-463.
-
(1993)
Nature
, vol.361
, pp. 460-463
-
-
Moya, M.1
Roberts, D.2
Novick, P.3
-
51
-
-
0026636994
-
The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo
-
Munder, T., and P. Furst. 1992. The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo. Mol. Cell. Biol. 12:2091-2099.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2091-2099
-
-
Munder, T.1
Furst, P.2
-
52
-
-
0028358785
-
Cloning of cDNAs encoding a cell-cycle-regulatory GTP-binding low-Mr (GBLM) protein, Ran/TC4, from micronucleated Tetrahymena thermophila and amicronucleated Tetrahymena pyriformis
-
Nagata, K.-I., T. Takemasa, S. Alam, T. Hattori, Y. Watanabe, and Y. Nozawa. 1994. Cloning of cDNAs encoding a cell-cycle-regulatory GTP-binding low-Mr (GBLM) protein, Ran/TC4, from micronucleated Tetrahymena thermophila and amicronucleated Tetrahymena pyriformis. Gene 144: 123-125.
-
(1994)
Gene
, vol.144
, pp. 123-125
-
-
Nagata, K.-I.1
Takemasa, T.2
Alam, S.3
Hattori, T.4
Watanabe, Y.5
Nozawa, Y.6
-
53
-
-
0032559211
-
Coupling Ras and Rac guanosine triphosphatases through the Ras exchanger Sos
-
Nimnual, A. S., B. A. Yatsula, and D. Bar-Sagi. 1998. Coupling Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Science 279:560-563.
-
(1998)
Science
, vol.279
, pp. 560-563
-
-
Nimnual, A.S.1
Yatsula, B.A.2
Bar-Sagi, D.3
-
54
-
-
0030860083
-
The diversity of Rab proteins in vesicle transport
-
Novick, P., and M. Zerial. 1997. The diversity of Rab proteins in vesicle transport. Curr. Opin. Cell Biol. 9:496-504.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 496-504
-
-
Novick, P.1
Zerial, M.2
-
55
-
-
0028239912
-
GTPases: Multifunctional molecular switches regulating vesicular traffic
-
Nuoffer, C., and W. E. Balch. 1994. GTPases: multifunctional molecular switches regulating vesicular traffic. Annu. Rev. Biochem. 63:949-990.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 949-990
-
-
Nuoffer, C.1
Balch, W.E.2
-
56
-
-
0028138578
-
Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras
-
Park, W., R. D. Mosteller, and D. Broek. 1994. Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras. Mol. Cell. Biol. 14:8117-8122.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8117-8122
-
-
Park, W.1
Mosteller, R.D.2
Broek, D.3
-
57
-
-
0028817697
-
Properties of the catalytic domain of Sdc25p, a yeast GDP/GTP exchange factor of Ras proteins
-
Poullet, P., J.-B. Crechet, A. Bernardi, and A. Parmeggiani. 1995. Properties of the catalytic domain of Sdc25p, a yeast GDP/GTP exchange factor of Ras proteins. Eur. J. Biochem. 227:537-544.
-
(1995)
Eur. J. Biochem.
, vol.227
, pp. 537-544
-
-
Poullet, P.1
Crechet, J.-B.2
Bernardi, A.3
Parmeggiani, A.4
-
58
-
-
0024599698
-
Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae
-
Powers, S., K. O'Neill, and M. Wigler. 1989. Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae. Mol. Cell. Biol. 9:390-395.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 390-395
-
-
Powers, S.1
O'Neill, K.2
Wigler, M.3
-
59
-
-
15844372678
-
Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors
-
Quilliam, L. A., M. M. Hisaka, S. Zhong, A. Lowry, R. D. Mosteller, J. Han, J. K. Drugan, D. Broek, S. L. Campbell, and C. J. Der. 1996. Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. J. Biol. Chem. 271:11076-11082.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11076-11082
-
-
Quilliam, L.A.1
Hisaka, M.M.2
Zhong, S.3
Lowry, A.4
Mosteller, R.D.5
Han, J.6
Drugan, J.K.7
Broek, D.8
Campbell, S.L.9
Der, C.J.10
-
60
-
-
0028147401
-
Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors
-
Quilliam, L. A., K. Kato, K.-M. Rabun, M.-M. Hisaka, S. Y. Huff, S. Campbell-Burk, and C. J. Der. 1994. Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors. Mol. Cell. Biol. 14:1113-1121.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1113-1121
-
-
Quilliam, L.A.1
Kato, K.2
Rabun, K.-M.3
Hisaka, M.-M.4
Huff, S.Y.5
Campbell-Burk, S.6
Der, C.J.7
-
61
-
-
0029294676
-
Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins
-
Quilliam, L. A., R. Khosravi-Far, S. Y. Huff, and C. J. Der. 1995. Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins. Bioessays 17:395-404.
-
(1995)
Bioessays
, vol.17
, pp. 395-404
-
-
Quilliam, L.A.1
Khosravi-Far, R.2
Huff, S.Y.3
Der, C.J.4
-
62
-
-
0031950849
-
GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport
-
Richardson, C. J., S. Jones, R. J. Litt, and N. Segev. 1998. GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport. Mol. Cell. Biol. 18:827-838.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 827-838
-
-
Richardson, C.J.1
Jones, S.2
Litt, R.J.3
Segev, N.4
-
63
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., P. H. Warne, A. Khwaja, B. M. Marte, D. Pappin, P. Das, M. D. Waterfield, A. Ridley, and J. Downward. 1997. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 89:457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
64
-
-
0029758214
-
p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins
-
Rosa, J. L., R. P. Casaroli-Marano, A. J. Buckler, S. Vilaro, and M. Barbacid. 1996. p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins. EMBO J. 15:4262-4273.
-
(1996)
EMBO J.
, vol.15
, pp. 4262-4273
-
-
Rosa, J.L.1
Casaroli-Marano, R.P.2
Buckler, A.J.3
Vilaro, S.4
Barbacid, M.5
-
65
-
-
0003903343
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
66
-
-
0025275582
-
Time-resolved x-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis
-
Schlichting, I., S. C. Almo, G. Rapp, K. Wilson, K. Petratos, A. Lentfer, A. Wittinghofer, W. Kabsch, E. F. Pai, and G. A. Pestko. 1990. Time-resolved x-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis. Nature 345:309-315.
-
(1990)
Nature
, vol.345
, pp. 309-315
-
-
Schlichting, I.1
Almo, S.C.2
Rapp, G.3
Wilson, K.4
Petratos, K.5
Lentfer, A.6
Wittinghofer, A.7
Kabsch, W.8
Pai, E.F.9
Pestko, G.A.10
-
67
-
-
0027393408
-
The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17
-
Schweighoffer, F., H. Cai, M. C. Chevallier-Multon, I. Fath, G. Cooper, and B. Tocque. 1993. The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17. Mol. Cell. Biol. 13:39-43.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 39-43
-
-
Schweighoffer, F.1
Cai, H.2
Chevallier-Multon, M.C.3
Fath, I.4
Cooper, G.5
Tocque, B.6
-
68
-
-
0028819526
-
Two distinct regions of Ras participate in functional interaction with GDP-GTP exchangers
-
Segal, M., I. Marbach, B. M. Willumsen, and A. Levitzki. 1995. Two distinct regions of Ras participate in functional interaction with GDP-GTP exchangers. Eur. J. Biochem. 228:96-101.
-
(1995)
Eur. J. Biochem.
, vol.228
, pp. 96-101
-
-
Segal, M.1
Marbach, I.2
Willumsen, B.M.3
Levitzki, A.4
-
69
-
-
0027175224
-
Residues crucial for Ras interaction with GDP-GTP exchangers
-
Segal, M., B. M. Willumsen, and A. Levitzki. 1993. Residues crucial for Ras interaction with GDP-GTP exchangers. Proc. Natl. Acad. Sci. USA 90:5564-5568.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5564-5568
-
-
Segal, M.1
Willumsen, B.M.2
Levitzki, A.3
-
70
-
-
0023369514
-
The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response
-
Segev, N., and D. Botstein. 1987. The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response. Mol. Cell. Biol. 7:2367-2377.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2367-2377
-
-
Segev, N.1
Botstein, D.2
-
71
-
-
0029118307
-
Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates
-
Self, A. J., and A. Hall. 1995. Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates. Methods Enzymol. 256:67-76.
-
(1995)
Methods Enzymol.
, vol.256
, pp. 67-76
-
-
Self, A.J.1
Hall, A.2
-
72
-
-
0003549085
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
Sherman, F., G. R. Fink, and J. B. Hicks. 1986. Laboratory course manual for methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
(1986)
Laboratory Course Manual for Methods in Yeast Genetics
-
-
Sherman, F.1
Fink, G.R.2
Hicks, J.B.3
-
73
-
-
0026628881
-
RAS residues that are distant from the GDP binding site play a critical role in dissociation factor-stimulated release of GDP
-
Verrotti, A. C., J.-B. Crechet, F. Di Blasi, G. Seidita, M. G. Mirisola, C. Kavounis, V. Nastopoulos, E. Burden, E. De Vendittis, A. Parmeggiani, and O. Fasano. 1992. RAS residues that are distant from the GDP binding site play a critical role in dissociation factor-stimulated release of GDP. EMBO J. 11:2855-2862.
-
(1992)
EMBO J.
, vol.11
, pp. 2855-2862
-
-
Verrotti, A.C.1
Crechet, J.-B.2
Di Blasi, F.3
Seidita, G.4
Mirisola, M.G.5
Kavounis, C.6
Nastopoulos, V.7
Burden, E.8
De Vendittis, E.9
Parmeggiani, A.10
Fasano, O.11
-
74
-
-
0023681723
-
Cloning of bovine GAP and its interaction with oncogenic ras p21
-
Vogel, U. S., R. A. Dixon, M. D. Schaber, R. E. Diehl, M. S. Marshall, E. M. Scolnick, I. S. Sigal, and J. B. Gibbs. 1988. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (London) 335:90-93.
-
(1988)
Nature (London)
, vol.335
, pp. 90-93
-
-
Vogel, U.S.1
Dixon, R.A.2
Schaber, M.D.3
Diehl, R.E.4
Marshall, M.S.5
Scolnick, E.M.6
Sigal, I.S.7
Gibbs, J.B.8
-
75
-
-
0031041373
-
Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G protein
-
Wada, M., H. H. Nakanishi, A. Satoh, H. Hirano, H. Obaishi, Y. Matsuura, and Y. Takai. 1997. Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G protein. J. Biol. Chem. 272:3875-3878.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3875-3878
-
-
Wada, M.1
Nakanishi, H.H.2
Satoh, A.3
Hirano, H.4
Obaishi, H.5
Matsuura, Y.6
Takai, Y.7
-
76
-
-
0030930514
-
Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles
-
Walch-Solimena, C., R. N. Collins, and P. Novick. 1997. Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J. Cell Biol. 137:1495-1509.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1495-1509
-
-
Walch-Solimena, C.1
Collins, R.N.2
Novick, P.3
-
77
-
-
0023392867
-
Biochemical properties of the ras-related YPT protein in yeast: A mutational analysis
-
Wangner, P., C. M. T. Molenaar, A. J. G. Rauth, R. Brokel, H. D. Schmitt, and D. Gallitz. 1987. Biochemical properties of the ras-related YPT protein in yeast: a mutational analysis. EMBO J. 6:2373-2379.
-
(1987)
EMBO J.
, vol.6
, pp. 2373-2379
-
-
Wangner, P.1
Molenaar, C.M.T.2
Rauth, A.J.G.3
Brokel, R.4
Schmitt, H.D.5
Gallitz, D.6
-
78
-
-
0031026132
-
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
-
Westwick, J. K., Q. T. Lambert, G. J. Clark, M. Symons, L. Van Aelst, R. G. Pestell, and C. J. Der. 1997. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol. Cell. Biol. 17:1324-1335.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1324-1335
-
-
Westwick, J.K.1
Lambert, Q.T.2
Clark, G.J.3
Symons, M.4
Van Aelst, L.5
Pestell, R.G.6
Der, C.J.7
-
79
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White, M. A., C. Nicolette, A. Minden, A. Polverino, L. van Aelst, M. Karin, and M. H. Wigler. 1995. Multiple Ras functions can contribute to mammalian cell transformation. Cell 80:533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicolette, C.2
Minden, A.3
Polverino, A.4
Van Aelst, L.5
Karin, M.6
Wigler, M.H.7
-
81
-
-
0028336749
-
Genetic evidence for a functional interaction between Saccharomyces cerevisiae CDC24 and CDC42
-
Ziman, M., and D. Johnson. 1994. Genetic evidence for a functional interaction between Saccharomyces cerevisiae CDC24 and CDC42. Yeast 10:463-474.
-
(1994)
Yeast
, vol.10
, pp. 463-474
-
-
Ziman, M.1
Johnson, D.2
|