Sec14p-like domains in NF1 and Dbl-like proteins indicate lipid regulation of Ras and Rho signaling

Current Biology

Volumn 9, Issue 6, 1999, Pages

  Aravind, L ^a   Neuwald, A F ^a   Ponting, C P ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033602422     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(99)80127-4     Document Type: Letter

References (20)

1. MS Boguski F McCormick Proteins regulating Ras and its relatives Nature 366 1993 643 654
2. R White P O'Connell Identification and characterization of the gene for neurofibromatosis type 1 Curr Opin Genet Dev 1 1991 15 19
3. GF Xu P O'Connell D Viskochil R Cawthon M Robertson M Culver D Dunn J Stevens R Gesteland R White The neurofibromatosis type 1 gene encodes a protein related to GAP Cell 62 1990 599 608
4. I Whitehead H Kirk R Kay Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor Oncogene 10 1995 713 721
5. JM Boyd S Malstrom T Subramanian LK Venkatesh U Schaeper B Elangovan C D'Sa-Eipper G Chinnadurai Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins Cell 79 1994 341 351
6. S Cockcroft Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic Bioessays 20 1998 423 432
7. A Bateman E Birney R Durbin SR Eddy RD Finn ELL Sonnhammer Pfam 3.1:1313 multiple alignments and profile HMMs match the majority of proteins Nucleic Acids Res 27 1999 260 262
8. K Hofmann P Bucher L Falquet A Bairoch The PROSITE database, its status in 1999 Nucleic Acids Res 27 1999 215 219
9. B Sha SE Phillips VA Bankaitis M Luo Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol- transfer protein Nature 391 1998 506 510
10. VA Bankaitis JR Aitken AE Cleves W Dowhan An essential role for a phospholipid transfer protein in yeast Golgi function Nature 347 1990 561 562
11. MR Alam RC Johnson DN Darlington TA Hand RE Mains BA Eipper Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme J Biol Chem 272 1997 12667 12675
12. V Colomer S Engelender AH Sharp K Duan JK Cooper A Lanahan G Lyford P Worley CA Ross Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain Hum Mol Genet 6 1997 1519 1525
13. A Debant C Serra-Pages K Seipel S O'Brien M Tang SH Park M Streuli The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac- specific and rho- specific guanine nucleotide exchange factor domains Proc Natl Acad Sci USA 93 1996 5466 5471
14. G Bollag F McCormick Differential regulation of rasGAP and neurofibromatosis gene product activities Nature 351 1991 576 579
15. M Golubic K Tanaka S Dobrowolski D Wood MH Tsai M Marshall F Tamanoi DW Stacey The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid EMBO J 10 1991 2897 2903
16. M Upadhyaya J Maynard M Osborn PS Harper Six novel mutations in the neurofibromatosis type 1 (NF1) gene Hum Mutat 10 1997 248 250
17. M Tassabehji T Strachan M Sharland A Colley D Donnai R Harris N Thakker Tandem duplication within a neurofibromatosis type 1 (NF1) gene exon in a family with features of Watson syndrome and Noonan syndrome Am J Hum Genet 53 1993 90 95
18. Y Horii JF Beeler K Sakaguchi M Tachibana T Miki A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways EMBO J 13 1994 4776 4786
19. D Ron SR Tronick SA Aaronson A Eva Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells EMBO J 7 1988 2465 2473
20. SF Altschul TL Madden AA Schaffer J Zhang Z Zhang W Miller DJ Lipman Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Nucleic Acids Res 25 1997 3389 3402