A novel costimulatory signaling in human T lymphocytes by a splice variant of CD28

Blood

Volumn 99, Issue 6, 2002, Pages 2138-2145

  Hanawa, Haruo ^a,b,c   Ma, Yong ^a,b,c   Mikolajczak, Sebastian A ^a,b,c   Charles, Matthew L ^a,b,c   Yoshida, Tetsuya ^a,b,c   Yoshida, Ryoko ^a,b,c   Strathdee, Craig A ^a,b,c   Litchfield, David W ^a,b,c   Ochi, Atsuo ^a,b,c  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b NIIGATA UNIVERSITY   (Japan)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; BINDING SITE; CONTROLLED STUDY; CROSS LINKING; EXON; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0037085769     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.6.2138     Document Type: Article

References (32)

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4. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
5. Regulation of self-tolerance by CD80/CD86 interactions
6. CD28 and apoptosis
7. Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites
8. Upstream-downstream: CD28 cosignaling pathways and T cell function
9. CD28 signals through acidic sphingomyelinase
10. Sphingomyelin-ceramide turnover in CD28 costimulatory signaling
11. CD28-costimulation activates cyclic AMP-responsive element-binding protein in T lymphocytes
12. CD3- and CD28-dependent induction of PDE7 required for T cell activation
13. The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A
14. NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
15. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta
16. Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals
17. Stimulation of CD28 with B7-2 promotes focal adhesion-like cell contacts where Rho family small G proteins accumulate in T cells
18. T lymphocyte costimulation mediated by reorganization of membrane microdomains
19. Identification of three alternatively spliced variants of human CD28 mRNA
20. The genomic organization of the CD28 gene: Implications for the regulation of CD28 mRNA expression and heterogeneity
21. Quantification of mRNA by non-radioactive RT-PCR and CCD imaging system
22. Cis-acting transcriptional regulatory sequences in the gibbon ape leukemia virus (GALV) long terminal repeat
23. Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors
24. Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins
25. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and Tcell-specific protein-tyrosine kinase ITK: Implications for T-cell costimulation
26. Role of 4-1 BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP
27. Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation
28. The alternatively spliced CD64 transcript Fcgamma-Rlb2 does not specify a surface-expressed isoform
29. A novel receptor involved in T-cell activation
30. Heteromultimeric complexes of CD40 ligand are present on the cell surface of human T lymphocytes
31. CD28 is an inducible Tcell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes
32. Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence