Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP)

Journal of Biological Chemistry

Volumn 277, Issue 45, 2002, Pages 43143-43151

  Lutz, Christina ^a   Nimpf, Johannes ^a   Jenny, Marcel ^b   Boecklinger, Karl ^a   Enzinger, Christiane ^b   Utermann, Gerd ^a   Baier Bitterlich, Gabriele ^b   Baier, Gottfried ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; MICROSCOPIC EXAMINATION;

RECOMBINANT FUSION;

PROTEINS;

ALPHA 2 MACROGLOBULIN; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN C JUN; RECOMBINANT PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ALPHA-MACROGLOBULINS; ANIMALS; CAMPTOTHECIN; CEREBELLUM; DNA PRIMERS; ENHANCER ELEMENTS (GENETICS); GENES, REPORTER; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; KINETICS; LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; PC12 CELLS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-JUN; RAC1 GTP-BINDING PROTEIN; RATS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA; CERVUS ELAPHUS;

EID: 0037044716     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204426200     Document Type: Article

References (65)

1. Herz, J. (2001) Neuron 29, 571-581
2. Herz, J., and Beffert, U. (2000) Nat. Rev. Neurosci. 1, 51-58
3. Krieger, M., and Herz, J. (1994) Annu. Rev. Biochem. 63, 601-637
4. Marzolo, M. P., von Bernhardi, R., Bu, G., and Inestrosa, N. C. (2000) J. Neurosci. Res. 60, 401-411
5. Herz, J., Clouthier, D. E., and Hammer, R. E. (1992) Cell 71, 411-421
6. May, P., Reddy, Y. K., and Herz, J. (2002) J. Biol. Chem. 277, 18736-18743
7. Trommsdorff, M., Borg, J. P., Margolis, B., and Herz, J. (1998) J. Biol. Chem. 273, 33556-33560
8. Willnow, T. E., Orth, K., and Herz, J. (1994) J. Biol. Chem. 269, 15827-15832
9. Kounnas, M. Z., Moir, R. D., Rebeck, G. W., Bush, A. I., Argraves, W. S., Tanzi, R. E., Hyman, B. T., and Strickland, D. K. (1995) Cell 82, 331-340
10. Herz, J., and Strickland, D. K. (2001) J. Clin. Invest. 108, 779-784
11. Kinoshita, A., Whelan, C. M., Smith, C. J., Mikhailenko, I., Rebeck, G. W., Strickland, D. K., and Hyman, B. T. (2001) J. Neurosci. 21, 8354-8361
12. Barnes, H., Larsen, B., Tyers, M., and van Der Geer, P. (2001) J. Biol. Chem. 276, 19119-19125
13. Loukinova, E., Ranganathan, S., Kuznetsov, S., Gorlatov, N., Migliorini, M. M., Loukinov, D., Ulery, P. G, Mikhailenko, I., Lawrence, D. A., and Strickland, D. K. (2002) J. Biol. Chem. 277, 15499-15506
14. Boucher, P., Liu, P., Gotthardt, M., Hiesberger, T., Anderson, R. G., and Herz, J. (2002) J. Biol. Chem. 277, 15507-15513
15. Gotthardt, M., Trommsdorff, M., Nevitt, M. F., Shelton, J., Richardson, J. A., Stockinger, W., Nimpf, J., and Herz, J. (2000) J. Biol. Chem. 275, 25616-25624
16. Stockinger, W., Brandes, C., Fasching, D., Hermann, M., Gotthardt, M., Herz, J., Schneider, W. J., and Nimpf, J. (2000) J. Biol. Chem. 275, 25625-25632
17. Chang, L., and Karin, M. (2001) Nature 410, 37-40
18. Russo, T., Faraonio, R., Minopoli, G., De Candia, P., De Renzis, S., and Zambrano, N. (1998) FEBS Lett. 434, 1-7
19. Matsuda, S., Yasukawa, T., Homma, Y., Ito, Y., Niikura, T., Hiraki, T., Hirai, S., Ohno, S., Kita, Y., Kawasumi, M., Kouyama, K., Yamamoto, T., Kyriakis, J. M., and Nishimoto, I. (2001) J. Neurosci. 21, 6597-6607
20. Scheinfeld, M. H., Roncarati, R., Vito, P., Lopez, P. A., Abdallah, M., and D'Adamio, L. (2002) J. Biol. Chem. 277, 3767-3775
21. Romeo, C., Kolanus, W., Amiot, M., and Seed, B. (1992) Cold Spring Harbor Symp. Quant. Biol. 57, 117-125
22. Kolanus, W., Romeo, C., and Seed, B. (1993) Cell 74, 171-183
23. Ghaffari-Tabrizi, N., Bauer, B., Villunger, A., Baier-Bitterlich, G., Altman, A., Utermann, G., Uberall, F., and Baier, G. (1999) Eur. J. Immunol. 29, 132-142
24. Villunger, A., Ghaffari-Tabrizi, N., Tinhofer, I., Krumbock, N., Bauer, B., Schneider, T., Kasibhatla, S., Greil, R., Baier-Bitterlich, G., Uberall, F., Green, D. R., and Baier, G. (1999) Eur. J. Immunol. 29, 3549-3561
25. Bonny, C., Nicod, P., and Waeber, G. (1998) J. Biol. Chem. 273, 1843-1846
26. Zeitlmann, L., Knorr, T., Knoll, M., Romeo, C., Sirim, P., and Kolanus, W. (1998) J. Biol. Chem. 273, 15445-15452
27. Hatten, M. E. (1985) J. Cell Biol. 100, 384-396
28. Enzinger, C., Wirleitner, B., Lutz, C., Bock, G., Tomaselli, B., Baier, G., Fuchs, D., Baier-Bitterlich, G. (2002) Eur J. Cell Biol. 81, 97-202
29. Bauer, B., Krumbock, N., Ghaffari-Tabrizi, N., Kampfer, S., Villunger, A., Wilda, M., Hameister, H., Utermann, G., Leitges, M., Uberall, F., and Baier, G. (2000) Eur. J. Immunol. 30, 3645-3654
30. Cavigelli, M., Dolfi, F., Claret, F. X., and Karin, M. (1995) EMBO J. 14, 5957-5964
31. Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., and Herz, J. (1999) Cell 97, 689-701
32. Herz, J., Gotthardt, M., and Willnow, T. E. (2000) Curr. Opin. Lipidol. 11, 161-166
33. Zhu, Y., Lin, J. H., Liao, H. L., Friedli, O., Jr., Verna, L., Marten, N. W., Straus, D. S., and Stemerman, M. B. (1998) Arterioscler. Thromb. Vasc. Biol. 18, 473-480
34. Zhuo, M., Holtzman, D. M., Li, Y., Osaka, H., DeMaro, J., Jacquin, M., and Bu, G. (2000) J. Neurosci. 20, 542-549
35. Roses, A. D., and Saunders, A. M. (1994) Curr. Opin. Biotechnol. 5, 663-667
36. Ho, Y. Y., Deckelbaum, R. J., Chen, Y., Vogel, T., and Talmage, D. A. (2001) J. Biol. Chem. 276, 43455-43462
37. Mao, B., Wu, W., Li, Y., Hoppe, D., Stannek, P., Glinka, A., and Niehrs, C. (2001) Nature 411, 321-325
38. Pinson, K. I., Brennan, J., Monkley, S., Avery, B. J., and Skarnes, W. C. (2000) Nature 407, 535-538
39. Tamai, K., Semenov, M., Kato, Y., Spokony, R., Liu, C., Katsuyama, Y., Hess, F., Saint-Jeannet, J. P., and He, X. (2000) Nature 407, 530-535
40. Yasuda, J., Whitmarsh, A. J., Cavanagh, J., Sharma, M., and Davis, R. J. (1999) Mol. Cell. Biol. 19, 7245-7254
41. Dickens, M., Rogers, J. S., Cavanagh, J., Raitano, A., Xia, Z., Halpern, J. R., Greenberg, M. E., Sawyers, C. L., and Davis, R. J. (1997) Science 277, 693-696
42. Fuchs, S. Y., Adler, V., Pincus, M. R., and Ronai, Z. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10541-10546
43. Buschmann, T., Potapova, O., Bar-Shira, A., Ivanov, V. N., Fuchs, S. Y., Henderson, S., Fried, V. A., Minamoto, T., Alarcon-Vargas, D., Pincus, M. R., Gaarde, W. A., Holbrook, N. J., Shiloh, Y., and Ronai, Z. (2001) Mol. Cell. Biol. 21, 2743-2754
44. Inamura, N., Enokido, Y., and Hatanaka, H. (2001) Brain Res. 904, 270-278
45. Kobayashi, K., and Tsukamoto, I. (2001) Biochim. Biophys. Acta 1537, 79-88
46. Hashimoto, Y., Jiang, H., Niikura, T., Ito, Y., Hagiwara, A., Umezawa, K., Abe, Y., Murayama, Y. Nishimoto, I. (2001) J. Neurosci. 20, 8401-8409
47. Verhey, K. J., Meyer, D., Deehan, R., Blenis, J., Schnapp, B. J., Rapoport, T. A., and Margolis, B. (2001) J. Cell Biol. 152, 959-970
48. Logan, S. K., Falasca, M., Hu, P., and Schlessinger, J. (1997) Mol. Cell. Biol. 17, 5784-5790
49. Lopez-Ilasaca, M., Crespo, P., Pellici, P. G., Gutkind, J. S., and Wetzker, R. (1997) Science 275, 394-397
50. Hashimoto, A., Kurosaki, M., Gotoh, N., Shibuya, M., and Kurosaki, T. (1999) J. Biol. Chem. 274, 20139-20143
51. Whitmarsh, A. J., and Davis, R. J. (2000) Nature 403, 255-256
52. Whitmarsh, A. J., Kuan, C. Y., Kennedy, N. J., Kelkar, N., Haydar, T. F., Mordes, J. P., Appel, M., Rossini, A. A., Jones, S. N., Flavell, R. A., Rakic, P., and Davis, R. J. (2001) Genes Dev. 15, 2421-2432
53. Sluss, H. K., Han, Z., Barrett, T., Davis, R. J., and Ip, Y. T. (1996) Genes Dev. 10, 2745-2758
54. Otto, I. M., Raabe, T., Rennefahrt, U. E., Bork, P., Rapp, U. R., and Kerkhoff, E. (2000) Curr. Biol. 10, 345-348
55. Kerkhoff, E., Simpson, J. C., Leberfinger, C. B., Otto, I. M., Doerks, T., Bork, P., Rapp, U. R., Raabe, T., and Pepperkok, R. (2001) Curr. Biol. 11, 1963-1968
56. Bellosta, S., Nathan, B. P., Orth, M., Dong, L. M., Mahley, R. W., and Pitas, R. E. (1995) J. Biol. Chem. 270, 27063-27071
57. Holtzman, D. M., Pitas, R. E., Kilbridge, J., Nathan, B., Mahley, R. W., Bu, G., and Schwartz, A. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9480-9484
58. Fagan, A. M., Bu, G., Sun, Y., Daugherty, A., and Holtzman, D. (1996) J. Biol. Chem. 271, 30121-30125
59. Postuma, R. B., Martins, R. N., Cappai, R., Beyreuther, K., Masters, C. L., Strickland, D. K., Mok, S. S., and Small, D. H. (1998) FEBS Lett. 428, 13-16
60. Narita, M., Bu, G., Holtzman, D. M., and Schwartz, A. L. (1997) J. Neurochem. 68, 587-595
61. Rozemuller, J. M., van der Valk, P., and Eikelenboom, P. (1992) Res. Immunol. 143, 646-649
62. Sheng, J. G., Mrak, R. E., and Griffin, W. S. (1997) Acta Neuropathol. (Berlin) 94, 1-5
63. Kang, D. E., Saitoh, T., Chen, X., Xia, Y., Masliah, E., Hansen, L. A., Thomas, R. G., Thal, L. J., and Katzman, R. (1997) Neurology 49, 56-61
64. Cao, X., and Sudhof, T. C. (2001) Science 293, 115-120
65. Weidemann, A., Eggert, S., Reinhard, F. B., Vogel, M., Paliga, K., Baier, G., Masters, C. L., Beyreuther, K., and Evin, G. (2002) Biochemistry 41, 2825-2835