7,8-dihydroneopterin induces apoptosis of Jurkat T-lymphocytes via a Bcl-2-sensitive pathway

European Journal of Cell Biology

Volumn 81, Issue 4, 2002, Pages 197-202

  Enzinger, Christiane ^a   Wirleitner, Barbara ^a   Lutz, Christina ^b   Böck, Günther ^c   Tomaselli, Bettina ^a   Baier, Gottfried ^b   Fuchs, Dietmar ^a   Baier Bitterlich, Gabriele ^a,d  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b Inst for Med Biol and Hum Genet   (Austria)

^c Institute for General and Experimental Pathology   (Austria)

^d Institute of Biochemistry   (Austria)

Author keywords

7,8 dihydroneopterin; Apoptosis; Bcl 2; CrmA; Jurkat T lymphocytes; Oxidative stress; Pteridines

Indexed keywords

7,8 DIHYDRONEOPTERIN; PROTEIN BCL 2; PTERIN DERIVATIVE; UNCLASSIFIED DRUG; 7,8-DIHYDRONEOPTERIN; ANTIOXIDANT; DRUG DERIVATIVE; ENZYME INHIBITOR; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; INTERLEUKIN-1BETA-CONVERTING ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NEOPTERIN; PTERIDINE DERIVATIVE; SERINE PROTEINASE INHIBITOR; STAUROSPORINE; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; ASSAY; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE CONSTRUCT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; T LYMPHOCYTE; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; APOPTOSIS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; JURKAT CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPTERIN; PROTO-ONCOGENE PROTEINS C-BCL-2; PTERIDINES; SERPINS; SIGNAL TRANSDUCTION; STAUROSPORINE; VIRAL PROTEINS;

EID: 0036011162     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00236     Document Type: Article

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