Effects of intra-hippocampal infusion of WAY-100635 on plus-maze behavior in mice: Influence of site of injection and prior test experience

Brain Research

Volumn 927, Issue 1, 2002, Pages 87-96

  Nunes de Souza, Ricardo Luiz ^a   Canto de Souza, Azair ^b   Rodgers, Robert John ^c  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

5 HT1A Receptor; Anxiety; Dorsal hippocampus; Elevated plus maze; Mouse; Ventral hippocampus

Indexed keywords

N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INFUSION; EXPERIENCE; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; HYPOTHESIS; INJECTION SITE; LOCOMOTION; MALE; MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; STIMULUS RESPONSE; TASK PERFORMANCE;

ANIMALS; ANXIETY; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE; MICROINJECTIONS; PIPERAZINES; PYRIDINES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN ANTAGONISTS;

EID: 0037039533     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03335-2     Document Type: Article

References (71)

1. 1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours, respectively
2. 1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties
3. An autoradiographic analysis of the differential ascending projections of the dorsal and median raphé nuclei in the rat
4. 1A receptors as targets for the development of novel anxiolytic drugs: Models, mechanisms and further directions
5. 1A receptor antagonists (+)-WAY 100135 and WAY 100635
6. 1A receptor ligands in the mouse
7. Different behavioural profiles of R-(+)- and S-(-)-enantiomers of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) in the murine elevated plus-maze
8. 1A
9. 1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190
10. 1A receptor antagonist, in the murine elevated plus-maze
11. Comparative behavioural profiles of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in the murine elevated plus-maze
12. 1A receptor ligands, LY293284, LY315712 and LY297996, on plus-maze anxiety in mice
13. 1A receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model
14. Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: Comparison with haloperidol
15. 1A antagonist, WAY 100635
16. 1A receptors that are negatively coupled to adenylate cyclase
17. Ethopharmacological analysis of rat behavior on the elevated plus-maze
18. 1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats
19. 1A receptor agonists: Recent developments and controversial issues
20. 1A receptors and anxiety
21. The influence of open arm ledges and maze experience in the elevated plus-maze
22. One-trial tolerance to the anxiolytic effects of benzodiazepines in the plus-maze
23. Behavioural detection of anxiolytic action
24. 1A receptor ligands in dorsal raphe and ventral hippocampus
25. 1A receptor modulation of anxiety in two ethological animal tests
26. 'One trial tolerance' to the anxiolytic actions of benzodiazepines in the elevated plus-maze, or the development of a phobic state?
27. Trial 2 in the elevated plus-maze: A different form of fear?
28. 1A receptor antagonists: Utility as research tools and therapeutic agents
29. 1A receptor antagonist
30. 1A receptor antagonist, WAY-100635
31. 1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze
32. A 5-min experience in the elevated plus-maze alters the state of the benzodiazepine receptor in the dorsal raphe nucleus
33. 1A receptor function: A link between anxiety and depression?
34. 5-Hydroxytrptamine-interacting drugs in animal models of anxiety: More than 30 years of research
35. 1A receptor antagonists
36. 1A receptor antagonists in three rat models of anxiety
37. The use of the rat plus-maze to discriminate non-selective and BZ-1 (ω1) selective, benzodiazepine receptor ligands
38. Contrasting behavioural effects of 8-OH-DPAT in the dorsal raphe nucleus and ventral hippocampus
39. Responses of Swiss-Webster mice to repeated plus-maze experience: Further evidence for a qualitative shift in emotional state?
40. 1B recognition sites
41. 1A receptor agonists and their inhibitory effects on the firing of serotonergic neurons in the rat?
42. 1A receptor antagonists and their interaction on the fear-potentiated startle response
43. 1 receptors
44. Intra-hippocampal buspirone in animal models of anxiety
45. 3H]WAY 100635 in the mouse
46. The use of a plus-maze to measure anxiety in the mouse
47. The septum and the hippocampus differentially mediate anxiolytic effects of R-(+)-8-OH-DPAT
48. Effects of centrally administered anxiolytic compounds in animal models of anxiety
49. 1A receptors on elevated plus-maze exploration after a single restraint experience
50. Antiaggressive and anxiolytic effects of gepirone in mice, and their attenuation by WAY 100635
51. 1A) receptors. 2. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties
52. 1A receptor antagonist (S)-UH-301 in rodents and monkeys
53. Effects of β-adrenoceptor ligands in the elevated X-maze 'anxiety' model and antagonism of the 'anxiogenic' response to 8-OH-DPAT
54. Serotonin receptors in the human brain. III. Autoradiographic mapping of serotonin-1 receptors
55. 1A compounds 8-hydroxy-2-(di-n-propylamino)tetralin and ipsapirone in the social interaction paradigm: Evidence of a presynaptic acton
56. 1A) receptor antagonist in rat brain
57. 1A) receptors in the anticonflict activity of β-adrenoceptor antagonists
58. 1A receptor modulators
59. 1A receptor antagonist, in the murine elevated plus-maze test
60. Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety
61. Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience
62. 1A receptor antagonists
63. 1A receptors play an important role in modulation of behavior of rats in a two-compartment black and white box
64. 1A receptor agonists 8-OH-DPAT, ipsapirone and buspirone in the rat
65. The role of 5-HT receptor subtypes in the anxiolytic effects of selective serotonin reuptake inhibitors in the rat ultrasonic vocalization test
66. 1A receptor agonists, partial agonists and a silent antagonist on the performance of the conditioned emotional response test in the rat
67. 1A receptor agonists
68. Anxiogenic stimuli in the elevated plus-maze
69. A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat