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Volumn 129, Issue 4, 1997, Pages 365-371

Anxiolytic-like profile of p-MPPI, a novel 5HT(1A) receptor antagonist, in the murine elevated plus-maze

Author keywords

5 HT(1A) receptors; Anxiety; Elevated plus maze; Mice; p MPPI

Indexed keywords

4 (2' METHOXYPHENYL) 1 [2' (2'' PYRIDINYL) 4 IODOBENZAMIDO] ETHYLPIPERAZINE; ANXIOLYTIC AGENT; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

EID: 0031057229     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050202     Document Type: Article
Times cited : (40)

References (54)
  • 2
    • 0028171876 scopus 로고
    • 1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively
    • 1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. Eur J Pharmacol 264:259-264
    • (1994) Eur J Pharmacol , vol.264 , pp. 259-264
    • Andrews, N.1    Hogg, S.2    Gonzalez, L.E.3    File, S.E.4
  • 3
    • 0027208571 scopus 로고
    • 1A receptors as targets for the development of novel anxiolytic drgus: Models, mechanisms and further directions
    • 1A receptors as targets for the development of novel anxiolytic drgus: models, mechanisms and further directions. Psychopharmacology 112:1-12
    • (1993) Psychopharmacology , vol.112 , pp. 1-12
    • Barrett, J.E.1    Vanover, K.2
  • 7
    • 0028305932 scopus 로고
    • Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo
    • Cadogan AK, Kendall DA, Fink H, Marsden CA (1994) Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo. Behav Pharmacol 5: 299-305
    • (1994) Behav Pharmacol , vol.5 , pp. 299-305
    • Cadogan, A.K.1    Kendall, D.A.2    Fink, H.3    Marsden, C.A.4
  • 8
    • 0030426163 scopus 로고    scopus 로고
    • Different behavioural profiles of R(+)-and S(-)-enantiomers of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) in the murine elevated plus-maze
    • in press
    • Cao B-J, Rodgers RJ (1996a) Different behavioural profiles of R(+)-and S(-)-enantiomers of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) in the murine elevated plus-maze. Behav Pharmacol 7 (in press)
    • (1996) Behav Pharmacol , vol.7
    • Cao, B.-J.1    Rodgers, R.J.2
  • 10
    • 8044234470 scopus 로고
    • 1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN 190
    • in press
    • 1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN 190. Pharmacol Biochem Behav (in press).
    • (1966) Pharmacol Biochem Behav
    • Cao, B.-J.1    Rodgers, R.J.2
  • 11
    • 0028971294 scopus 로고
    • 3) receptor anagonists increase rates of punished responding in rats
    • 3) receptor anagonists increase rates of punished responding in rats. Pharmacol Biochem Behav 52:621-676
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 621-676
    • Cervo, L.1    Samanin, R.2
  • 14
    • 0027139227 scopus 로고
    • An ethological analysis of the effects of chloridazpoxide and bretazenil (Ro 16-6028) in the murine elevated plus-maze
    • Cole JC, Rodgers RJ (1993) An ethological analysis of the effects of chloridazpoxide and bretazenil (Ro 16-6028) in the murine elevated plus-maze. Behav Pharmacol 4:573-580
    • (1993) Behav Pharmacol , vol.4 , pp. 573-580
    • Cole, J.C.1    Rodgers, R.J.2
  • 15
    • 0028332455 scopus 로고
    • Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: Comparison with haloperidol
    • Cole JC, Rodgers RJ (1994) Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol. Psychopharmacology 114:288-296
    • (1994) Psychopharmacology , vol.114 , pp. 288-296
    • Cole, J.C.1    Rodgers, R.J.2
  • 16
    • 0029081397 scopus 로고
    • Ethological comparison of the effects of diazepam and acture/chronic imipramine on the behaviour of mice in the elevated plus-maze
    • Cole JC, Rodgers RJ (1995) Ethological comparison of the effects of diazepam and acture/chronic imipramine on the behaviour of mice in the elevated plus-maze. Pharmacol Biochem Behav 52:473-478
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 473-478
    • Cole, J.C.1    Rodgers, R.J.2
  • 19
    • 0028990742 scopus 로고
    • 1A receptor agonists: Recent developments and controversial issues
    • 1A receptor agonists: recent developments and controversial issues. Psychopharmacology 121: 1-26
    • (1995) Psychopharmacology , vol.121 , pp. 1-26
    • De Vry, J.1
  • 20
    • 0001817804 scopus 로고
    • 1A receptor and anxiety
    • Dourish CT, Ahlenius S, Hutson PH (eds) Ellis Horwood, Chichester
    • 1A receptors. Ellis Horwood, Chichester, pp 261-277
    • (1987) 1A Receptors , pp. 261-277
    • Dourish, C.T.1
  • 21
    • 0027474372 scopus 로고
    • Social interaction and elevated plus-maze tests: Changes in release and uptake of 5-HT and GABA
    • File SE, Zangrossi H, Andrews N (1993) Social interaction and elevated plus-maze tests: changes in release and uptake of 5-HT and GABA. Neuropharmacology 32:217-221
    • (1993) Neuropharmacology , vol.32 , pp. 217-221
    • File, S.E.1    Zangrossi, H.2    Andrews, N.3
  • 22
    • 0030010685 scopus 로고    scopus 로고
    • 1A receptor modulation of anxiety in two ethological animal tests
    • 1A receptor modulation of anxiety in two ethological animal tests. J Neurosci 16: 4810-4815
    • (1996) J Neurosci , vol.16 , pp. 4810-4815
    • File, S.E.1    Gonzalez, L.E.2    Andrews, N.3
  • 26
    • 0002774116 scopus 로고
    • Single unit recordings from freely-moving animals provide evidence that WAY 100635, but not (S)-WAY 100135, blocks the action of endogenous serotonin at the 5-HT receptor
    • Fornal C, Metzler CW, Veasey SC, McCreary AC, Dourish CT, Jacobs BL (1994) Single unit recordings from freely-moving animals provide evidence that WAY 100635, but not (S)-WAY 100135, blocks the action of endogenous serotonin at the 5-HT receptor. Br J Pharmacol 112:92P
    • (1994) Br J Pharmacol , vol.112
    • Fornal, C.1    Metzler, C.W.2    Veasey, S.C.3    McCreary, A.C.4    Dourish, C.T.5    Jacobs, B.L.6
  • 28
    • 0028986825 scopus 로고
    • 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
    • Griebel G (1995) 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacol Ther 65:319-395
    • (1995) Pharmacol Ther , vol.65 , pp. 319-395
    • Griebel, G.1
  • 31
    • 0028935942 scopus 로고
    • 5-Hydroxytryptamine pathways in anxiety and its treatment
    • Handley SL (1995) 5-Hydroxytryptamine pathways in anxiety and its treatment. Pharmacol Ther 66:103-148
    • (1995) Pharmacol Ther , vol.66 , pp. 103-148
    • Handley, S.L.1
  • 32
    • 0021706422 scopus 로고
    • 5-HT and anxiety
    • Iversen SD (1984) 5-HT and anxiety. Neuropharmacology 23: 1553-1560
    • (1984) Neuropharmacology , vol.23 , pp. 1553-1560
    • Iversen, S.D.1
  • 36
    • 0028881530 scopus 로고
    • 125I] p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: In vitro binding and autoradiographic studies
    • 125I] p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: In vitro binding and autoradiographic studies. J Pharmacol Exp Ther 272:429-437
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 429-437
    • Kung, M.-P.1    Frederick, D.2    Mu, M.3    Zhang, Z.-P.4    Kung, H.F.5
  • 37
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister RG (1987) The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 92:180-185
    • (1987) Psychopharmacology , vol.92 , pp. 180-185
    • Lister, R.G.1
  • 39
    • 0026357341 scopus 로고
    • Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans
    • Murphy DL, Lesch KP, Aulakh CS, Pigott TA (1991) Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans. Pharmacol Rev 43:527-552
    • (1991) Pharmacol Rev , vol.43 , pp. 527-552
    • Murphy, D.L.1    Lesch, K.P.2    Aulakh, C.S.3    Pigott, T.A.4
  • 40
    • 0024415699 scopus 로고
    • Panic attacks, buspirone and serotonin function
    • Norman TR, Judd FK (1989) Panic attacks, buspirone and serotonin function. Lancet 2:615
    • (1989) Lancet , vol.2 , pp. 615
    • Norman, T.R.1    Judd, F.K.2
  • 42
    • 0002358097 scopus 로고
    • The elevated plus-maze: Pharmacology, methodology and ethology
    • Cooper SJ, Hendrie CA (eds) Wiley, Chichester
    • Rodgers RJ, Cole JC (1994a) The elevated plus-maze: pharmacology, methodology and ethology. In: Cooper SJ, Hendrie CA (eds) Ethology and psychopharmacology. Wiley, Chichester, pp 9-44
    • (1994) Ethology and Psychopharmacology , pp. 9-44
    • Rodgers, R.J.1    Cole, J.C.2
  • 43
    • 0028111617 scopus 로고
    • 1A receptor antagonist, in the murine elevated plus-maze test
    • 1A receptor antagonist, in the murine elevated plus-maze test. Eur J Pharmacol 261:321-325
    • (1994) Eur J Pharmacol , vol.261 , pp. 321-325
    • Rodgers, R.J.1    Cole, J.C.2
  • 44
    • 0029083245 scopus 로고
    • Factor analysis of spatiotemporal and ethological measures in the elevated plus-maze test of anxiety
    • Rodgers RJ, Johnson NJT (1995) Factor analysis of spatiotemporal and ethological measures in the elevated plus-maze test of anxiety. Pharmacol Biochem Behav 52:297-303
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 297-303
    • Rodgers, R.J.1    Johnson, N.J.T.2
  • 45
    • 0027056458 scopus 로고
    • Anxiogenic-like effects of fluprazine and etoprazine in the mouse elevated plus-maze: Profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP
    • Rodgers RJ, Cole JC, Cobain MR, Daly P, Doran PJ, Eells JR, Wallis P (1992) Anxiogenic-like effects of fluprazine and etoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP. Behav Pharmacol 3:621-634
    • (1992) Behav Pharmacol , vol.3 , pp. 621-634
    • Rodgers, R.J.1    Cole, J.C.2    Cobain, M.R.3    Daly, P.4    Doran, P.J.5    Eells, J.R.6    Wallis, P.7
  • 47
    • 0029665346 scopus 로고    scopus 로고
    • 1A receptor antagonists
    • 1A receptor antagonists. Behav Brain Res 73:153-156
    • (1996) Behav Brain Res , vol.73 , pp. 153-156
    • Routledge, C.1
  • 51
    • 0030424356 scopus 로고    scopus 로고
    • 4-(2′-Methoxy-phenyl)-1-[2′-N-2″-pyridinyl-p- iodobenzamido]-ethyl-piperazine and 4-(2′-methoxy-phenyl)-1-[2′-(N-2″-pyridinyl)-p- fluorobenzamido]-ethyl-piperazine two new antagonists at pre- and postsynaptic serotonin-1A receptors
    • Thielen RJ, Fangon NB, Frazer A (1996) 4-(2′-Methoxy-phenyl)-1-[2′-N-2″-pyridinyl)-p-iodobenzamido]- ethyl-piperazine and 4-(2′-methoxy-phenyl)-1-[2′-(N-2″-pyridinyl)-p- fluorobenzamido]-ethyl-piperazine two new antagonists at pre- and postsynaptic serotonin-1A receptors. J Pharmacol Exp Ther 277:661-670
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 661-670
    • Thielen, R.J.1    Fangon, N.B.2    Frazer, A.3
  • 53
    • 0026440925 scopus 로고
    • Effects of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze
    • Wright IK, Upton N, Marsden CA (1992) Effects of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze. Psychopharmacology 109:338-346
    • (1992) Psychopharmacology , vol.109 , pp. 338-346
    • Wright, I.K.1    Upton, N.2    Marsden, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.