The selective serotonin (5-HT)1(A) receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats a comparison with other anxiolytic agents

Psychopharmacology

Volumn 152, Issue 1, 2000, Pages 55-66

  Dekeyne, A ^a   Brocco, M ^a   Adhumeau, A ^a   Gobert, A ^a   Millan, M J ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

5 HT1(A) receptor; Anxiety; Microdialysis; S15535; Social interaction; Vogel conflict

Indexed keywords

1 (1,4 BENZODIOXAN 5 YL) 4 (2 INDANYL)PIPERAZINE; 1,2,3,5 TETRAHYDRO 5 METHYL 1 (3 PYRIDYLCARBAMOYL)PYRROLO[2,3 F]INDOLE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ANXIOLYTIC AGENT; BUSPIRONE; DIAZEPAM; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 2C ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; CONFLICT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; HIPPOCAMPUS; LOCOMOTION; MALE; MICRODIALYSIS; MODEL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; SOCIAL INTERACTION; TRANQUILIZING ACTIVITY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMAL; ANTI-ANXIETY AGENTS; ANTI-ANXIETY AGENTS, BENZODIAZEPINE; ATAXIA; COMPARATIVE STUDY; CONFLICT (PSYCHOLOGY); DIALYSIS; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; INTERPERSONAL RELATIONS; MALE; MOTOR ACTIVITY; PIPERAZINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0033801680     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130000449     Document Type: Article

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