메뉴 건너뛰기




Volumn 36, Issue 8, 1997, Pages 1089-1097

Comparative behavioural profiles of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in the murine elevated plus-maze

Author keywords

1 PP; 5 HT(1A) receptors; Anxiety; Buspirone; Elevated plus maze; Mice; Proadifen

Indexed keywords

1 (2 PYRIMIDINYL)PIPERAZINE; BUSPIRONE; DRUG METABOLITE; ENZYME INHIBITOR; PROADIFEN;

EID: 0030806429     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00094-4     Document Type: Article
Times cited : (39)

References (41)
  • 1
    • 0030426724 scopus 로고    scopus 로고
    • Novel benzodioxan derivative, 5-{3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy}-1,3-benzodioxole Hc1 (MKC-242), with anxiolytic-like and antidepressant-like effects in animal models
    • Abe M., Tabata R., Saito K.-I., Matsuda T., Baba A. and Egawa M. (1996) Novel benzodioxan derivative, 5-{3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy}-1,3-benzodioxole Hc1 (MKC-242), with anxiolytic-like and antidepressant-like effects in animal models. Journal of Pharmacology and Experimental Therapeutics 278: 898-905.
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.278 , pp. 898-905
    • Abe, M.1    Tabata, R.2    Saito, K.-I.3    Matsuda, T.4    Baba, A.5    Egawa, M.6
  • 2
    • 0027255756 scopus 로고
    • Comparison of the anticonflict effect of buspirone and its major metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in rats
    • Amano M., Goto A., Sakai A., Achiha M., Hara N., Takahashi N., Hara C. and Ogawa N. (1993) Comparison of the anticonflict effect of buspirone and its major metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in rats. Japanese Journal of Pharmacology 61: 311-317.
    • (1993) Japanese Journal of Pharmacology , vol.61 , pp. 311-317
    • Amano, M.1    Goto, A.2    Sakai, A.3    Achiha, M.4    Hara, N.5    Takahashi, N.6    Hara, C.7    Ogawa, N.8
  • 3
    • 0030426163 scopus 로고    scopus 로고
    • Different behavioural profiles of R(+)- and S(-)-enantiomers of 8-hydroxy-2-(din-propylamino)tetralin (8-OH-DPAT) in the marine elevated plus-maze
    • Cao B.-J. and Rodgers R. J. (1996) Different behavioural profiles of R(+)- and S(-)-enantiomers of 8-hydroxy-2-(din-propylamino)tetralin (8-OH-DPAT) in the marine elevated plus-maze. Behavioural Pharmacology 7: 810-819.
    • (1996) Behavioural Pharmacology , vol.7 , pp. 810-819
    • Cao, B.-J.1    Rodgers, R.J.2
  • 4
    • 0031057229 scopus 로고    scopus 로고
    • 1A receptor antagonist, has anxiolytic-like profile in the murine elevated plus-maze
    • 1A receptor antagonist, has anxiolytic-like profile in the murine elevated plus-maze. Psychopharmacology 129: 365-371.
    • (1997) Psychopharmacology , vol.129 , pp. 365-371
    • Cao, B.-J.1    Rodgers, R.J.2
  • 6
    • 0030609834 scopus 로고    scopus 로고
    • 1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN 190
    • In press
    • 1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN 190. Pharmacology, Biochemistry and Behaviour. In press.
    • (1997) Pharmacology, Biochemistry and Behaviour
    • Cao, B.-J.1    Rodgers, R.J.2
  • 7
    • 0024204356 scopus 로고    scopus 로고
    • Different effects of intracerebral and systemic administration of buspirone in the forced swimming test: Involvement of a metabolite
    • Cervo L., Grignaschi G. and Samanin R. 1997c Different effects of intracerebral and systemic administration of buspirone in the forced swimming test: involvement of a metabolite. Life Sciences 43: 2095-2102.
    • (1997) Life Sciences , vol.43 , pp. 2095-2102
    • Cervo, L.1    Grignaschi, G.2    Samanin, R.3
  • 8
    • 0028332455 scopus 로고
    • Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: Comparison with haloperidol
    • Cole J. C. and Rodgers R. J. (1994) Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol. Psychopharmacology 114: 288-296.
    • (1994) Psychopharmacology , vol.114 , pp. 288-296
    • Cole, J.C.1    Rodgers, R.J.2
  • 11
    • 0028204275 scopus 로고
    • Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat
    • Cullen W. K. and Rowan M. J. (1994) Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat. Pharmacology, Biochemistry and Behaviour 48: 301-306.
    • (1994) Pharmacology, Biochemistry and Behaviour , vol.48 , pp. 301-306
    • Cullen, W.K.1    Rowan, M.J.2
  • 12
    • 0027482177 scopus 로고
    • Shocked-induced ultrasonic vocalization in young adult rats: A model for testing putative anti-anxiety drugs
    • De Vry J., Benz U., Schreiber R. and Traber J. (1993) Shocked-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs. European Journal of Pharmacology 249: 331-339.
    • (1993) European Journal of Pharmacology , vol.249 , pp. 331-339
    • De Vry, J.1    Benz, U.2    Schreiber, R.3    Traber, J.4
  • 14
    • 18344404314 scopus 로고
    • Concentration of buspirone and 1-(2-pyrimidinyl)-piperazine, a metabolite, in rat brain
    • Gammans R. E., Mayol R. E. and Eison M. S. (1983) Concentration of buspirone and 1-(2-pyrimidinyl)-piperazine, a metabolite, in rat brain. Federation Proceedings 42: 377.
    • (1983) Federation Proceedings , vol.42 , pp. 377
    • Gammans, R.E.1    Mayol, R.E.2    Eison, M.S.3
  • 15
    • 0028986825 scopus 로고
    • 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
    • Griebel G. (1995) 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacological Therapy 65: 319-395.
    • (1995) Pharmacological Therapy , vol.65 , pp. 319-395
    • Griebel, G.1
  • 17
    • 0023747624 scopus 로고
    • 2-Adrenoceptor antagonist activity may account for the effects of buspirone in an anticonflict test in the rat
    • 2-Adrenoceptor antagonist activity may account for the effects of buspirone in an anticonflict test in the rat. European Journal of Pharmacology 155: 129-137.
    • (1988) European Journal of Pharmacology , vol.155 , pp. 129-137
    • Gower, A.J.1    Tricklebank, M.D.2
  • 18
    • 0027729920 scopus 로고
    • Multiple serotonin mechanisms in animal models of anxiety: Environmental, emotional and cognitive factors
    • Handley S. L., McBlane J. W., Critchley M. A. E. and Njung'e K. (1993) Multiple serotonin mechanisms in animal models of anxiety: environmental, emotional and cognitive factors. Behavioral Brain Research 58: 203-210.
    • (1993) Behavioral Brain Research , vol.58 , pp. 203-210
    • Handley, S.L.1    McBlane, J.W.2    Critchley, M.A.E.3    Njung'e, K.4
  • 19
    • 0021183219 scopus 로고
    • Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour
    • Handley S. L. and Mithani S. (1984) Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour. Naunyn-Schmiedeberg's Archives of Pharmacology 327: 1-5.
    • (1984) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.327 , pp. 1-5
    • Handley, S.L.1    Mithani, S.2
  • 21
    • 0029867314 scopus 로고    scopus 로고
    • A review of the validity and variability of the elevated plus-maze as an animal model of anxiety
    • Hogg S. (1996) A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacology, Biochemistry and Behaviour 54: 21-30.
    • (1996) Pharmacology, Biochemistry and Behaviour , vol.54 , pp. 21-30
    • Hogg, S.1
  • 22
    • 0002454197 scopus 로고
    • Autonomic and psychic effects of yohimbine hydrochloride
    • Holmberg G. and Gershon S. (1961) Autonomic and psychic effects of yohimbine hydrochloride. Psychopharmacologia 2: 93-106.
    • (1961) Psychopharmacologia , vol.2 , pp. 93-106
    • Holmberg, G.1    Gershon, S.2
  • 25
    • 0025735039 scopus 로고
    • 1A agonists in the learned helplessness paradigm in rats
    • 1A agonists in the learned helplessness paradigm in rats. Psychopharmacology 104: 275-278.
    • (1991) Psychopharmacology , vol.104 , pp. 275-278
    • Martin, P.1
  • 26
    • 0029616637 scopus 로고
    • Novel benzodioxan derivative, 5-{3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy}-1,3-benzodioxole Hcl (MKC-242), with a highly potent and selective agonist activity at rat central serotonin 1A receptors
    • Matsuda T., Yoshikawa T., Suzuki M., Anaso S., Somboonthum P., Takuma K., Nakano Y., Morita T., Nakasu Y., Kim H. S., Egawa M., Tobe A. and Baba A. (1995) Novel benzodioxan derivative, 5-{3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy}-1,3-benzodioxole Hcl (MKC-242), with a highly potent and selective agonist activity at rat central serotonin 1A receptors. Japanese Journal of Pharmacology 69: 357-366.
    • (1995) Japanese Journal of Pharmacology , vol.69 , pp. 357-366
    • Matsuda, T.1    Yoshikawa, T.2    Suzuki, M.3    Anaso, S.4    Somboonthum, P.5    Takuma, K.6    Nakano, Y.7    Morita, T.8    Nakasu, Y.9    Kim, H.S.10    Egawa, M.11    Tobe, A.12    Baba, A.13
  • 29
    • 0027446907 scopus 로고
    • In vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of α2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus
    • Mongeau R., Blier P. and Montigny C. de (1993) In vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of α2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus. Naunyn-Schmiedeberg's Archives of Pharmacology 347: 266-272.
    • (1993) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.347 , pp. 266-272
    • Mongeau, R.1    Blier, P.2    De Montigny, C.3
  • 30
    • 0024328772 scopus 로고
    • An evaluation of the elevated plus-maze test using the novel anxiolytic buspirone
    • Moser P. C. (1989) An evaluation of the elevated plus-maze test using the novel anxiolytic buspirone. Psychopharmacology 99: 48-53.
    • (1989) Psychopharmacology , vol.99 , pp. 48-53
    • Moser, P.C.1
  • 31
    • 0025167249 scopus 로고
    • Cerebral pharcokinetics of ipsapirone in rats after different routes of administration
    • Nocon H., Daniel W., Danek L. and Melzacka M. (1990) Cerebral pharcokinetics of ipsapirone in rats after different routes of administration. Journal of Pharmacy and Pharmacology 42: 642-645.
    • (1990) Journal of Pharmacy and Pharmacology , vol.42 , pp. 642-645
    • Nocon, H.1    Daniel, W.2    Danek, L.3    Melzacka, M.4
  • 32
    • 0025180487 scopus 로고
    • Antidepressant-like activity of ipsapirone, buspirone and gepirone in the forced swimming test in rats pretreated with proadifen
    • Przegalinski E., Tatarczynska E. and Chojnacka-Wojcik E. (1990) Antidepressant-like activity of ipsapirone, buspirone and gepirone in the forced swimming test in rats pretreated with proadifen. European Journal of Pharmacology 183: 1906.
    • (1990) European Journal of Pharmacology , vol.183 , pp. 1906
    • Przegalinski, E.1    Tatarczynska, E.2    Chojnacka-Wojcik, E.3
  • 33
    • 0028982068 scopus 로고
    • 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat
    • 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat. British Journal of Pharmacology 116: 2081-2089.
    • (1995) British Journal of Pharmacology , vol.116 , pp. 2081-2089
    • Redfern, W.S.1    Williams, A.2
  • 34
    • 0002358097 scopus 로고
    • The elevated plus-maze: Pharmacology, methodology and ethology
    • (Cooper S. J. and Hendrie C. A., Eds), J. Wiley and Sons, Chichester
    • Rodgers R. J. and Cole J. C. (1994a) The elevated plus-maze: pharmacology, methodology and ethology. In Ethology and psychopharmacology (Cooper S. J. and Hendrie C. A., Eds), pp. 9-44. J. Wiley and Sons, Chichester.
    • (1994) Ethology and Psychopharmacology , pp. 9-44
    • Rodgers, R.J.1    Cole, J.C.2
  • 36
    • 0029083245 scopus 로고
    • Factor analysis of spatiotemporal and ethological measures in the elevated plus-maze test of anxiety
    • Rodgers R. J. and Johnson N. J. T. (1995) Factor analysis of spatiotemporal and ethological measures in the elevated plus-maze test of anxiety. Pharmacology, Biochemistry and Behaviour 52: 297-303.
    • (1995) Pharmacology, Biochemistry and Behaviour , vol.52 , pp. 297-303
    • Rodgers, R.J.1    Johnson, N.J.T.2
  • 37
    • 0026725815 scopus 로고
    • Discriminative stimulus properties of 8-OH-DPAT: Relationship to affinity for 5-HT1A receptors
    • Sanger D. J. and Schoemaker H. (1992) Discriminative stimulus properties of 8-OH-DPAT: relationship to affinity for 5-HT1A receptors. Psychopharmacology 108: 85-92.
    • (1992) Psychopharmacology , vol.108 , pp. 85-92
    • Sanger, D.J.1    Schoemaker, H.2
  • 40
    • 0025739970 scopus 로고
    • The association of buspirone and its metabolite 1-pyrimidinyl piperazine in the remission of comorbid anxiety with depressive symptoms
    • Tollefson G. D., Lancaster S. P. and Montague-Clouse J. (1991) The association of buspirone and its metabolite 1-pyrimidinyl piperazine in the remission of comorbid anxiety with depressive symptoms. Psychopharmacology Bulletin 27: 163-170.
    • (1991) Psychopharmacology Bulletin , vol.27 , pp. 163-170
    • Tollefson, G.D.1    Lancaster, S.P.2    Montague-Clouse, J.3
  • 41
    • 0026440925 scopus 로고
    • Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze
    • Wright I. K., Upton N. and Marsden C. A. (1992) Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze. Psychopharmacology 109: 338-346.
    • (1992) Psychopharmacology , vol.109 , pp. 338-346
    • Wright, I.K.1    Upton, N.2    Marsden, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.