Gαq and Gβγ regulate PAR-1 signaling of thrombin-induced NF-κB activation and ICAM-1 transcription in endothelial cells

Circulation Research

Volumn 91, Issue 5, 2002, Pages 398-405

  Rahman, Arshad ^a   True, Andrea L ^a   Anwar, Khandaker N ^a   Ye, Richard D ^a   Voyno Yasenetskaya, Tatyana A ^a   Malik, Asrar B ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Akt; G proteins; Intercellular adhesion molecule 1; Nuclear factor B; Protein kinase C

Indexed keywords

DIMER; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 1; RGS PROTEIN; SCAVENGER; THREONYLPHENYLALANYLLEUCYLLEUCYLARGINYLASPARAGINYLPROLYLASPARAGINYLASPARTYL LYSINE; THROMBIN; TRANSDUCIN; UNCLASSIFIED DRUG; AKT1 PROTEIN, HUMAN; CHUK PROTEIN, HUMAN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; I KAPPA B KINASE; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; ISOENZYME; OLIGOPEPTIDE; ONCOPROTEIN; PRKCD PROTEIN, HUMAN; PROTEIN KINASE C DELTA; PROTEIN SERINE THREONINE KINASE; THROMBIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBUNIT; GENE ACTIVATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR MODEL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PLASMID; VASCULAR ENDOTHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ENDOTHELIUM, VASCULAR; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; I-KAPPA B KINASE; INTERCELLULAR ADHESION MOLECULE-1; ISOENZYMES; MUTATION; NF-KAPPA B; OLIGOPEPTIDES; PLASMIDS; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; THROMBIN; TRANSCRIPTION, GENETIC;

EID: 0037031487     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000033520.95242.A2     Document Type: Article

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