Antineoplastic agents 440. Asymmetric synthesis and evaluation of the combretastatin A-1 SAR probes (1S,2S)- and (1R,2R)-1,2-dihydroxy-1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3'' ,4'',5''-trimethoxyphenyl)-ethane

Journal of Natural Products

Volumn 63, Issue 7, 2000, Pages 969-974

  Pettit, George R ^a   Lippert III, John W ^a   Herald, Delbert L ^a   Hamel, Ernest ^b   Pettit, Robin K ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMBRETASTATIN; COMBRETASTATIN A1; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL GROWTH; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HYDROXYLATION; ISOMERISM; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG SCREENING ASSAYS, ANTITUMOR; ETHYLENE GLYCOLS; GUAIACOL; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR PROBES; STEREOISOMERISM; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TREES; TUMOR CELLS, CULTURED;

ANIMALIA; COMBRETUM; COMBRETUM CAFFRUM; MURINAE;

EID: 0033854914     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0000623     Document Type: Article

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