Binding of the neurotoxin fasciculin 2 to the acetylcholinesterase peripheral site drastically reduces the association and dissociation rate constants for N-methylacridinium binding to the active site

Biochemistry

Volumn 35, Issue 3, 1996, Pages 685-690

  Rosenberry, Terrone L ^a   Rabl, Carl Roland ^b   Neumann, Eberhard ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BIELEFELD UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; FASCICULIN; NEUROTOXIN; SNAKE VENOM;

ARTICLE; BINDING AFFINITY; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; TOXIN ANALYSIS;

ACETYLCHOLINESTERASE; ACRIDINES; BINDING SITES; CHOLINESTERASE INHIBITORS; ELAPID VENOMS; HUMANS; NEUROTOXINS; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 0030050490     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952431d     Document Type: Article

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