SUMO-I co-localized with mutant atrophin-I with expanded polyglutamines accelerates intranuclear aggregation and cell death

NeuroReport

Volumn 13, Issue 17, 2002, Pages 2359-2364

  Terashima, Tomoya ^a   Kawai, Hiromichi ^a   Fujitani, Masashi ^a   Maeda, Kengo ^a   Yasuda, Hitoshi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Aggregation; Atrophin I; CAG; DRPLA; Polyglutamine; SUMO I

Indexed keywords

ATROPHIN 1; MUTANT PROTEIN; POLYGLUTAMINE; PROTEIN DERIVATIVE; SUMO 1 PROTEIN; UNCLASSIFIED DRUG; ATROPHIN-1; NERVE PROTEIN; PEPTIDE;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN; CARBOXY TERMINAL SEQUENCE; CELL COUNT; CELL INCLUSION; CELL NUCLEUS; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENTATORUBROPALLIDOLUYSIAN ATROPHY; DISEASE MODEL; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; NERVE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RAT; ANIMAL; CELL DEATH; GENETICS; METABOLISM; MIDDLE AGED; MYOCLONUS EPILEPSY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRINUCLEOTIDE REPEAT;

ANIMALS; BRAIN; CELL DEATH; CELL NUCLEUS; HUMANS; INCLUSION BODIES; MIDDLE AGED; MYOCLONIC EPILEPSIES, PROGRESSIVE; NERVE TISSUE PROTEINS; NEURONS; PC12 CELLS; PEPTIDES; RATS; SUMO-1 PROTEIN; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0037015833     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200212030-00038     Document Type: Article

References (24)

1. Ross CA. Neuron 15, 493-496 (1995).
2. Paulson HL and Fischbeck KH. Annu Rev Neurosci 19, 79-107 (1996).
3. Yazawa I, Nukina N, Hashida H et al. Nature Genet 10, 99-103 (1995).
4. Schilling G, Wood JD, Duran K et al. Neuron 24, 275-286 (1999).
5. Cummings CJ, Mancini MA, Antalffy B et al. Nature Genet 19, 148-154 (1998).
6. Chai Y, Koppenhafer SL, Shoesmith SJ et al. Hum Mol Genet 8, 673-682 (1999).
7. Yasuda S, Inoue K, Hirabayashi M et al. Genes Cells 4, 743-756 (1999).
8. Kazantsev A, Preisinger E, Dranovsky A et al. Proc Natl Acad Sci USA 96, 11404-11409 (1999).
9. Steffan JS, Kazantsev A, Spasic-Boskovic O et al. Proc Natl Acad Sci USA 97, 6763-6768 (2000).
10. Liu YF. J Biol Chem 273, 28873-28877 (1998).
11. Nucifora FC Jr, Sasaki M, Peters MF et al. Science 291, 2423-2428 (2001).
12. Saitoh H, Pu RT and Dasso M. Trends Biochem Sci 22, 374-376 (1997).
13. Mahajan R, Gerace L and Melchior F. J Cell Biol 140, 259-270 (1998).
14. Muller S, Matunis MJ and Dejean A. EMBO J 17, 61-70 (1998).
15. Rodriguez MS, Desterro JM, Lain S et al. EMBO J 18, 6455-6461 (1999).
16. Muller S, Berger M, Lehembre F et al. J Biol Chem 275, 13321-13329 (2000).
17. Desterro JM, Rodriguez MS and Hay RT. Mol Cell 2, 233-239 (1998).
18. Hayashi Y, Kakita A, Yamada M et al. Acta Neuropathol (Berl) 96, 547-552 (1998).
19. Cummings CJ, Reinstein E, Sun Y et al. Neuron 24, 879-892 (1999).
20. Shimohata T, Nakajima T, Yamada M et al. Nature Genet 26, 29-36 (2000).
21. Seeler JS, Marchio A, Lossort R et al. Mol Cell Biol 21, 3314-3324 (2001).
22. Goodson ML, Hong Y, Rogers R et al. J Biol Chem 276, 18513-18518 (2001).
23. Li H, Leo C, Zhu J et al. Mol Cell Biol 20, 1784-1796 (2000).
24. Ishov AM, Sotnikov AG, Negorev D et al. J Cell Biol 147, 221-234 (1999).