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Volumn 41, Issue 35, 2002, Pages 10827-10833

An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis

(6) Kim, Beom Seok a Cropp, T Ashton a Florova, Galina a Lindsay, Yuko a Sherman, David H b Reynolds, Kevin A a

a VIRGINIA COMMONWEALTH UNIVERSITY (United States)

b UNIVERSITY OF MINNESOTA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDES;

CATALYSIS; SYNTHESIS (CHEMICAL);

ENZYMES;

6 DEOXYERYTHRONOLIDE B SYNTHASE; ERYTHROMYCIN; FUNGAL ENZYME; LACTONE; PIKROMYCIN; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME BINDING; HYPOTHESIS; MOLECULAR INTERACTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SACCHAROPOLYSPORA; SACCHAROPOLYSPORA ERYTHREA; SEQUENCE HOMOLOGY; STREPTOMYCES VENEZUELAE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; DRUG INTERACTIONS; ERYTHROMYCIN; GLYCOSIDES; LACTONES; MACROLIDES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PALMITOYL-COA HYDROLASE; PEPTIDE FRAGMENTS; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; SACCHAROPOLYSPORA; SEQUENCE DELETION; STREPTOMYCES;

ILEX COOKII; SACCHAROPOLYSPORA; STREPTOMYCES; STREPTOMYCES VENEZUELAE;

EID: 0037015162 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi0256779 Document Type: Article

Times cited : (29)

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