Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability

EMBO Journal

Volumn 20, Issue 14, 2001, Pages 3657-3666

  Garami, A ^a   Ilg, T ^a  

^a MAX PLANCK INST FÜR BIOLOGIE   (Germany)

Author keywords

GDP mannose pyrophosphorylase; Leishmania; Mannose; Metabolism; Virulence

Indexed keywords

GLYCOCONJUGATE; GLYCOLIPID; GLYCOPROTEIN; GUANOSINE DIPHOSPHATE MANNOSE; GUANOSINE DIPHOSPHATE MANNOSE PHOSPHORYLASE; MANNOSE; PHOSPHORYLASE; PROTEOGLYCAN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL LYSATE; ENZYME ACTIVITY; GENE DELETION; GENE MUTATION; GLYCOSYLATION; LEISHMANIA MEXICANA; LETHALITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REACTION ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE DELETION; GENE TARGETING; GENES, PROTOZOAN; GLYCOLIPIDS; GLYCOPROTEINS; LEISHMANIA MEXICANA; MACROPHAGES, PERITONEAL; MANNOSE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEOTIDYLTRANSFERASES; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE;

EID: 0035898610     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.14.3657     Document Type: Article

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