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Angewandte Chemie - International Edition

Volumn 41, Issue 17, 2002, Pages 3177-3180

Deracemization of α-methylbenzylamine using an enzyme obtained by in vitro evolution

(5) Alexeeva, Marina a Enright, Alexis a Dawson, Michael J b Mahmoudian, Mahmoud b Turner, Nicholas J a

a UNIVERSITY OF EDINBURGH (United Kingdom)

b GLAXOSMITHKLINE (United Kingdom)

Author keywords

Amino acids; Deracemization; Enzyme catalysis; Reduction

Indexed keywords

CATALYST SELECTIVITY; ENZYMES;

DERACEMIZATION; ENANTIOSELECTIVITY;

ORGANIC COMPOUNDS;

1-PHENETHYLAMINE; ALPHA METHYLBENZYLAMINE; AMINE OXIDASE (COPPER CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING); PEPTIDE LIBRARY; PHENETHYLAMINE DERIVATIVE;

ARTICLE; ASPERGILLUS NIGER; CATALYSIS; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; ENANTIOSELECTIVITY; ENZYME ANALYSIS; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; METABOLISM; METHODOLOGY; MOLECULAR CLONING; MOLECULAR EVOLUTION; OXIDATION REDUCTION REACTION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRODUCTIVITY; RACEMIC MIXTURE; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS; STEREOISOMERISM; SYNTHESIS;

AMINE OXIDASE (COPPER-CONTAINING); ASPERGILLUS NIGER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DIRECTED MOLECULAR EVOLUTION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PEPTIDE LIBRARY; PHENETHYLAMINES; STEREOISOMERISM;

EID: 0037008967 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3773(20020902)41:17<3177::AID-ANIE3177>3.0.CO;2-P Document Type: Article

Times cited : (216)

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