-
1
-
-
0030812206
-
Association between CpG island methylation and microsatellite instability in colorectal cancer
-
Ahuja N, Mohan AL, Li Q, Stolker JM, Herman JH, Hamilton SR, Baylin SB, Issa JP (1997) Association between CpG island methylation and microsatellite instability in colorectal cancer. Cancer Res 57: 3370-3374
-
(1997)
Cancer Res.
, vol.57
, pp. 3370-3374
-
-
Ahuja, N.1
Mohan, A.L.2
Li, Q.3
Stolker, J.M.4
Herman, J.H.5
Hamilton, S.R.6
Baylin, S.B.7
Issa, J.P.8
-
2
-
-
0020625970
-
Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach
-
Barranco SC, Townsend CM, Cacilda Casartelli BG, Macik NL, Burger WR, Boerwinkle WR, Gourley WK (1983) Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach. Cancer Res 43: 1703-1709
-
(1983)
Cancer Res.
, vol.43
, pp. 1703-1709
-
-
Barranco, S.C.1
Townsend, C.M.2
Cacilda Casartelli, B.G.3
Macik, N.L.4
Burger, W.R.5
Boerwinkle, W.R.6
Gourley, W.K.7
-
3
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP (1998) Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res 72: 141-196
-
(1998)
Adv. Cancer Res.
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
4
-
-
0028033422
-
Rates of p 16(MTS1) mutations in primary tumors with 9p loss
-
Cairns P, Mao L, Merlo A, Lee DJ, Schwab D, Eby Y, Tokino K, Van der Riet P, Blauground JE, Sidransky D (1994) Rates of p 16(MTS1) mutations in primary tumors with 9p loss. Science 265: 415-416
-
(1994)
Science
, vol.265
, pp. 415-416
-
-
Cairns, P.1
Mao, L.2
Merlo, A.3
Lee, D.J.4
Schwab, D.5
Eby, Y.6
Tokino, K.7
Van der Riet, P.8
Blauground, J.E.9
Sidransky, D.10
-
7
-
-
9444276546
-
ARF, and CDK4 in familial melanoma: Analysis of a clinic-based population
-
ARF, and CDK4 in familial melanoma: analysis of a clinic-based population, Proc Natl Acad Sci (Wash) 93: 8541-8545
-
Proc. Natl. Acad. Sci. (Wash)
, vol.93
, pp. 8541-8545
-
-
Fitzgerald, M.G.1
Harkin, D.P.2
Silva-Arrieta, S.3
MacDonald, D.J.4
Lucchina, L.C.5
Unsal, H.6
O'Neill, E.7
Koh, J.8
Finkelstein, D.M.9
Isselbacher, K.J.10
Sober, A.J.11
Haber, D.A.12
-
9
-
-
0021232786
-
Analysis of DNA ploidy pattern of gastric carcinomas of Japanease
-
Hattori T, Hosakawa Y, Fukuda M, Sugihara H, Hamada S, Takamatsu T, Nakanishi K, Tsuchihashi Y, Kitamura T, Fujita S (1984) Analysis of DNA ploidy pattern of gastric carcinomas of Japanease. Cancer 54: 1591-1597
-
(1984)
Cancer
, vol.54
, pp. 1591-1597
-
-
Hattori, T.1
Hosakawa, Y.2
Fukuda, M.3
Sugihara, H.4
Hamada, S.5
Takamatsu, T.6
Nakanishi, K.7
Tsuchihashi, Y.8
Kitamura, T.9
Fujita, S.10
-
10
-
-
9844219749
-
High frequency stimultaneous loss of p16- and p16beta-gene expression in squamous-cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach
-
Hayashi K, Metzger R, Salonga D, Danenberg K, Leichman LP, Fink U, Sendler A, Kelsen D, Schwartz GK, Groshen S, Lenz H, Janenberg PV (1997) High frequency stimultaneous loss of p16- and p16beta-gene expression in squamous-cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach. Oncogene 15: 1481-1488
-
(1997)
Oncogene
, vol.15
, pp. 1481-1488
-
-
Hayashi, K.1
Metzger, R.2
Salonga, D.3
Danenberg, K.4
Leichman, L.P.5
Fink, U.6
Sendler, A.7
Kelsen, D.8
Schwartz, G.K.9
Groshen, S.10
Lenz, H.11
Janenberg, P.V.12
-
11
-
-
0028845142
-
Inactivation of the CDK2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, Lapidus RG, Issa J-PJ, Davidson NE, Sidransky D, Baylin SB (1995) Inactivation of the CDK2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55: 4525-4530
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.-P.J.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
12
-
-
0029843950
-
Methylation specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB (1996) Methylation specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93: 9821-9826
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
13
-
-
13144266670
-
Incidence and functional consequence of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Wilson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB (1998) Incidence and functional consequence of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 95: 6870-6875
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
Markowitz, S.7
Wilson, J.K.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
14
-
-
0028059506
-
Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines
-
Igaki H, Sasaki H, Kishi T, Sakamoto H, Tachimori Y, Kato H, Watanabe H, Sugimura T, Terada M (1994) Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines. Biochem Biophys Res Commun 203: 1090-1095
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.203
, pp. 1090-1095
-
-
Igaki, H.1
Sasaki, H.2
Kishi, T.3
Sakamoto, H.4
Tachimori, Y.5
Kato, H.6
Watanabe, H.7
Sugimura, T.8
Terada, M.9
-
15
-
-
0029131251
-
Mutation frequency of the p16/CDKN2 gene in primary gastric cancers in upper digestive tract
-
Igaki H, Sasaki H, Tachimori Y, Kato H, Watanabe H, Kimura T, Harada Y, Sugimura T, Terada M (1995) Mutation frequency of the p16/CDKN2 gene in primary gastric cancers in upper digestive tract. Cancer Res 55: 3421-3423
-
(1995)
Cancer Res.
, vol.55
, pp. 3421-3423
-
-
Igaki, H.1
Sasaki, H.2
Tachimori, Y.3
Kato, H.4
Watanabe, H.5
Kimura, T.6
Harada, Y.7
Sugimura, T.8
Terada, M.9
-
17
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigan SV, Stockert E, Day III RS, Johnson BE, Skolnick MH (1994) A cell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436-440
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigan, S.V.6
Stockert, E.7
Day R.S. III8
Johnson, B.E.9
Skolnick, M.H.10
-
18
-
-
0030728468
-
ARF
-
ARF. Cell 91: 649-659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
19
-
-
0028276666
-
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
-
Kim H, Jen J, Vogelstein B, Hamilton SR (1994) Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 145: 148-156
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 148-156
-
-
Kim, H.1
Jen, J.2
Vogelstein, B.3
Hamilton, S.R.4
-
20
-
-
0029664483
-
INK4a: A gene with dual capacity to encode unrelated proteins that inhibit cell cycle progression
-
INK4a: a gene with dual capacity to encode unrelated proteins that inhibit cell cycle progression. Oncogene 12: 2041-2044
-
(1996)
Oncogene
, vol.12
, pp. 2041-2044
-
-
Lasen, C.J.1
-
21
-
-
12644292106
-
The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma
-
Lauren P (1965) The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta pathol Microbial Scand 64: 31-49
-
(1965)
Acta Pathol. Microbial. Scand.
, vol.64
, pp. 31-49
-
-
Lauren, P.1
-
22
-
-
9544251503
-
p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro
-
Liggett WH, Jr Sewll DA, Rocco J, Ahrendt SA, Koch W, Sidransky D (1996) p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro. Cancer Res 67: 4119-4123
-
(1996)
Cancer Res.
, vol.67
, pp. 4119-4123
-
-
Liggett W.H., Jr.1
Sewll, D.A.2
Rocco, J.3
Ahrendt, S.A.4
Koch, W.5
Sidransky, D.6
-
23
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathologic variables and family history
-
Lothe RA, Peltomaki P, Meling GI, Aaltonen LA, Nystrom Lathi M, Pylkkane L, Heimdal K, Andersen TI, Moller P, Rognum TO, Fossa SD, Haidorsen T, Langmark F, Brogger A, de la Chapelle A, Borresen AL (1993) Genomic instability in colorectal cancer: relationship to clinicopathologic variables and family history. Cancer Res 53, 5849-5852
-
(1993)
Cancer Res.
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
Aaltonen, L.A.4
Nystrom Lathi, M.5
Pylkkane, L.6
Heimdal, K.7
Andersen, T.I.8
Moller, P.9
Rognum, T.O.10
Fossa, S.D.11
Haidorsen, T.12
Langmark, F.13
Brogger, A.14
de la Chapelle, A.15
Borresen, A.L.16
-
24
-
-
0029113003
-
The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence dose not occur between gastric adenoma and adenocarcinoma
-
Maesawa C, Tamura G, Suzuki Y, Ogasawara S, Sakata K, Kashiwaba M, Satodate R (1995) The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence dose not occur between gastric adenoma and adenocarcinoma. J Pathol 176: 249-258
-
(1995)
J. Pathol.
, vol.176
, pp. 249-258
-
-
Maesawa, C.1
Tamura, G.2
Suzuki, Y.3
Ogasawara, S.4
Sakata, K.5
Kashiwaba, M.6
Satodate, R.7
-
25
-
-
0032403183
-
Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer
-
Markl IDC, Jones PA (1998) Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer. Cancer Res 58: 5348-5353
-
(1998)
Cancer Res.
, vol.58
, pp. 5348-5353
-
-
Markl, I.D.C.1
Jones, P.A.2
-
26
-
-
0029011539
-
5′ CpG-island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gamrielson E, Burger PC, Baylin SB, Sidransky D (1995) 5′ CpG-island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nature Med 1: 686-692
-
(1995)
Nature Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gamrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
27
-
-
0036216630
-
Different roles of p53 between Epstein-Barr Virus-positive and -negative gastric carcinomas of matched histology
-
Moritani S, Sugihara H, Kushima R., Hattori T (2002) Different roles of p53 between Epstein-Barr Virus-positive and -negative gastric carcinomas of matched histology. Virchow Arch 440: 367-375
-
(2002)
Virchow Arch.
, vol.440
, pp. 367-375
-
-
Moritani, S.1
Sugihara, H.2
Kushima, R.3
Hattori, T.4
-
28
-
-
0029587551
-
Alternative reading frames of INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ (1995) Alternative reading frames of INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83: 993-1000
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
29
-
-
0033592584
-
Inactivation of the INK4A/ARF locus frequency coexists with TP53 mutations in non-small cell lung cancer
-
Sanchez-Cespedes M, Reed AL, Buta M, Wu L, Westra WH, Herman JG, Yang SC, Jen J, Sidransky D (1999) Inactivation of the INK4A/ARF locus frequency coexists with TP53 mutations in non-small cell lung cancer. Oncogene 18: 5843-5849
-
(1999)
Oncogene
, vol.18
, pp. 5843-5849
-
-
Sanchez-Cespedes, M.1
Reed, A.L.2
Buta, M.3
Wu, L.4
Westra, W.H.5
Herman, J.G.6
Yang, S.C.7
Jen, J.8
Sidransky, D.9
-
31
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
(19939)
-
Serrano M, Hannon GJ, Beach D (19939) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.) 366: 704-707
-
Nature (Lond.)
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
32
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
Sherr CJ (1998) Tumor surveillance via the ARF-p53 pathway. Genes Dev 12: 2434-2442
-
(1998)
Genes Dev.
, vol.12
, pp. 2434-2442
-
-
Sherr, C.J.1
-
33
-
-
0342748644
-
Correlation of p 16 hypermethylation with the p16 protein loss in sporadic gastric carcinomas
-
Shim YH, Kang GH, Ro JY (2000) Correlation of p 16 hypermethylation with the p16 protein loss in sporadic gastric carcinomas. Lab Invest 80: 689-695
-
(2000)
Lab. Invest.
, vol.80
, pp. 689-695
-
-
Shim, Y.H.1
Kang, G.H.2
Ro, J.Y.3
-
34
-
-
0034662110
-
Methylation of specific CpG sites in the promoter region could significantly down-regulate p16 INK4a expression in gastric adenocacinoma
-
Song SH, Jong HS, Choi HH, Kang SH, Ryu MH, Kim NK, Kim WH, Bang YJ (2000) Methylation of specific CpG sites in the promoter region could significantly down-regulate p16 INK4a expression in gastric adenocacinoma. Int J Cancer 87: 236-240
-
(2000)
Int. J. Cancer
, vol.87
, pp. 236-240
-
-
Song, S.H.1
Jong, H.S.2
Choi, H.H.3
Kang, S.H.4
Ryu, M.H.5
Kim, N.K.6
Kim, W.H.7
Bang, Y.J.8
-
35
-
-
0029060657
-
Complex structure and regulation of the p16 (MTS1) locus
-
Stones S, Jiang P, Dayananth P, Tavtigian SV, Katcher H, Parry D, Peters G, Kamb A (1995) Complex structure and regulation of the p16 (MTS1) locus. Cancer Res 55: 2988-2994
-
(1995)
Cancer Res.
, vol.55
, pp. 2988-2994
-
-
Stones, S.1
Jiang, P.2
Dayananth, P.3
Tavtigian, S.V.4
Katcher, H.5
Parry, D.6
Peters, G.7
Kamb, A.8
-
36
-
-
0027408380
-
Progression of signet ring cell carcinomas in the human stomach
-
Sugihara H, Hattori T, Fukuda M, Katsura K, Fujita S (1993) Progression of signet ring cell carcinomas in the human stomach. Cancer 71: 1938-1947
-
(1993)
Cancer
, vol.71
, pp. 1938-1947
-
-
Sugihara, H.1
Hattori, T.2
Fukuda, M.3
Katsura, K.4
Fujita, S.5
-
37
-
-
0032848687
-
Distinct methylation pattern and microsatellite instability in sporadic gastric cancer
-
Suzuki H, Itoh F, Toyota M, Kikuchi T, Kakiuchi H, Hinoda Y, Imai K (1999) Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. Int J Cancer 83: 309-313
-
(1999)
Int. J. Cancer
, vol.83
, pp. 309-313
-
-
Suzuki, H.1
Itoh, F.2
Toyota, M.3
Kikuchi, T.4
Kakiuchi, H.5
Hinoda, Y.6
Imai, K.7
-
38
-
-
0033229890
-
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype
-
Toyota M, Ahuja N, Suzuki H, Itoh F, Toyota MO, Imai K, Baylin SB, Issa JJ (1999) Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res 59: 5442-6438
-
(1999)
Cancer Res.
, vol.59
, pp. 5442-6438
-
-
Toyota, M.1
Ahuja, N.2
Suzuki, H.3
Itoh, F.4
Toyota, M.O.5
Imai, K.6
Baylin, S.B.7
Issa, J.J.8
-
39
-
-
0030668305
-
Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer
-
Tsujimoto H, Sugihara H, Hagiwara A, Hattori T (1997) Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer. Virchow Arch 431: 383-389
-
(1997)
Virchow Arch.
, vol.431
, pp. 383-389
-
-
Tsujimoto, H.1
Sugihara, H.2
Hagiwara, A.3
Hattori, T.4
-
40
-
-
0030885597
-
Microsatellite instability, DNA ploidy, and mutation of transforming growth factor-β receptor type II gene in sporadic gastric cancer
-
Tsujimoto H, Sugihara H, Hagiwara A, Hattori T (1997) Microsatellite instability, DNA ploidy, and mutation of transforming growth factor-β receptor type II gene in sporadic gastric cancer. Cancer J 10: 211-216
-
(1997)
Cancer J.
, vol.10
, pp. 211-216
-
-
Tsujimoto, H.1
Sugihara, H.2
Hagiwara, A.3
Hattori, T.4
-
41
-
-
0032569736
-
Expression of p161NK/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
-
Vonlanthen S, Heighway J, Tschan MP, Borner MM, Altermatt HJ, Kappeler A, Tobler A, Fey MF, Thatcher N, Yarbrough WG, Betticher DC (1998) Expression of p161NK/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene 17: 2779-2785
-
(1998)
Oncogene
, vol.17
, pp. 2779-2785
-
-
Vonlanthen, S.1
Heighway, J.2
Tschan, M.P.3
Borner, M.M.4
Altermatt, H.J.5
Kappeler, A.6
Tobler, A.7
Fey, M.F.8
Thatcher, N.9
Yarbrough, W.G.10
Betticher, D.C.11
-
42
-
-
0033678874
-
Molecular charachteristics of eight gastric cancer cell lines established in Japan
-
Yokozaki H (2000) Molecular charachteristics of eight gastric cancer cell lines established in Japan. Pathol Int, 50: 767-777
-
(2000)
Pathol. Int.
, vol.50
, pp. 767-777
-
-
Yokozaki, H.1
-
43
-
-
0035124351
-
Genetic and epigenetic changes in stomach cancer
-
Yokozaki H, Yasui W, Tahara E (2001) Genetic and epigenetic changes in stomach cancer. Int Rev Cytol 204: 49-95
-
(2001)
Int. Rev. Cytol.
, vol.204
, pp. 49-95
-
-
Yokozaki, H.1
Yasui, W.2
Tahara, E.3
|