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Volumn 40, Issue C, 2002, Pages 63-105

3 Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of Hiv-1

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; QUINAZOLINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 0036987892     PISSN: 00796468     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6468(08)70082-1     Document Type: Article
Times cited : (23)

References (72)
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    • The White House, Office of the Press Secretary: A National Security Strategy for a New Century, January 5, 2000.
    • (2000) A National Security Strategy for a
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    • 77956672633 scopus 로고    scopus 로고
    • Information obtained from package inserts for indinavir (taken without food, ritonavir (taken with food to increase absorption, saquinavir taken with food to increase absorption
    • Information obtained from package inserts for indinavir (taken without food), ritonavir (taken with food to increase absorption), saquinavir (taken with food to increase absorption).
  • 12
    • 77956657510 scopus 로고    scopus 로고
    • Information on adverse events can be found in the package inserts or on the internet at http://www.aidsmeds.com/lessons/Drug_Chart.htm.
    • Information on adverse events can be found in the package inserts or on the internet at http://www.aidsmeds.com/lessons/Drug_Chart.htm.
  • 35
    • 77956665035 scopus 로고    scopus 로고
    • Britcher, S. F., Lumma, W. C., Goldman, M. E., Lyle, T. A., Huff, J. R., Payne, L. S., Quesada, M. L., Young, S. D., Sanders, W. M., Sanderson, P. E., Tucker, T. J. EP-00530994, 1993.
    • Britcher, S. F., Lumma, W. C., Goldman, M. E., Lyle, T. A., Huff, J. R., Payne, L. S., Quesada, M. L., Young, S. D., Sanders, W. M., Sanderson, P. E., Tucker, T. J. EP-00530994, 1993.
  • 45
    • 77956680738 scopus 로고    scopus 로고
    • Bacheler, L., Weislow, O., Snyder, S., Hanna, G., D'Aquila, R. and the SUSTIVA Resistance Study Team. Abstract presented at the 12th World AIDS Conference, Geneva, Switzerland, June 29-July 3, 1998.
    • Bacheler, L., Weislow, O., Snyder, S., Hanna, G., D'Aquila, R. and the SUSTIVA Resistance Study Team. Abstract presented at the 12th World AIDS Conference, Geneva, Switzerland, June 29-July 3, 1998.
  • 53
    • 77956661519 scopus 로고    scopus 로고
    • The biological activity presented for efavirenz is that of the single enantiomer and, unless reported otherwise, the activity reported for all other compounds is that of the racemate
    • The biological activity presented for efavirenz is that of the single enantiomer and, unless reported otherwise, the activity reported for all other compounds is that of the racemate.
  • 55
    • 77956657509 scopus 로고    scopus 로고
    • Cocuzza, A. J., Chidester, D. R., Cordova, B. C., Erickson-Viitanen, S., Trainor, G. L., Ko, S. S. To be submitted to Bioorg. Med. Chem. Lett.
    • Cocuzza, A. J., Chidester, D. R., Cordova, B. C., Erickson-Viitanen, S., Trainor, G. L., Ko, S. S. To be submitted to Bioorg. Med. Chem. Lett.
  • 57
    • 77956683803 scopus 로고    scopus 로고
    • The racemates contain only 50% of the active enantiomer, and the incorrect enantiomers (the R-isomer) are essentially inactive in the biological assays. Therefore, the activity of the single enantiomers would be expected to be approximately one-half that of the racemic values.
    • The racemates contain only 50% of the active enantiomer, and the incorrect enantiomers (the R-isomer) are essentially inactive in the biological assays. Therefore, the activity of the single enantiomers would be expected to be approximately one-half that of the racemic values.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.