AZT incorporation into mitochondria: Study in a human myeloid cell line

DNA and Cell Biology

Volumn 15, Issue 5, 1996, Pages 363-366

  Nusbaum, Neil J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; THYMIDINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; BONE MARROW TOXICITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IRON METABOLISM; MITOCHONDRIAL MYOPATHY; MITOCHONDRION; PRIORITY JOURNAL; VIRUS CELL INTERACTION;

HUMAN IMMUNODEFICIENCY VIRUS; MAMMALIA;

EID: 0029976922     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1996.15.363     Document Type: Article

References (4)

1. ABRAHAM, N.G., CHERTKOV, J.L., STAUDINGER, R., JIANG, S., LUTTON, J.D., ARGANI, I., LEVERE, R.D., and KAPPAS, A. (1993). Long-term bone marrow stromal and hemopoietic toxicity to AZT: Protective role of heme and IL-1. Exp. Hematol. 21, 263-268.
2. AGARWAL, R.P., and MIAN, A.M. (1991). Thymidine and zidovudine metabolism in chronically zidovudine-exposed cells in vitro. Biochem. Pharmacol. 42, 905-911.
3. ARNAUDO, E., DALAKAS, M., SHANSKE, S., MORALES, C.T., DIMAURO, S., and SCHON, E.A. (1991). Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet 337, 508-510.
4. BORST, P., and KROON, A.M. (1969). Mitochondrial DNA: Physieochemical properties, replication, and genetic function. Int. Rev. Cytol. 26, 107-190 at 146.