Transcriptional regulation of the Icant-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: Role for transcription factor EGR1

Journal of Experimental Medicine

Volumn 183, Issue 4, 1996, Pages 1747-1759

  Maltzman, Jonathan S ^a   Carman, Julie A ^a   Monroe, John G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE ANTIGEN RECEPTOR; PHORBOL ESTER; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL ADHESION; CELL MIGRATION; ELECTROPHORETIC MOBILITY; GENETIC TRANSCRIPTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION;

ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; BINDING SITES; CLONE CELLS; CONSENSUS SEQUENCE; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PHORBOL ESTERS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, ANTIGEN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029864377     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.4.1747     Document Type: Article

References (59)

1. Cambier, J.C., C.M. Pleiman, and M.R. Clark. 1994. Signal transduction by the B cell antigen receptor and its coreceptors. Annu. Rev. Immunol. 12:457-486.
2. Parker, D.C. 1993. T cell-dependent B cell activation. Annu. Rev. Immunol. 11:331-360.
3. Scholl, P.R., and R.S. Geha. 1994. MHC class II signaling in B-cell activation. Immunol. Today. 15:418-422.
4. Durie, F.H., T.M. Foy, S.R. Masters, J.D. Laman, and R.J. Noelle. 1994. The role of CD40 in the regulation of humoral and cell-mediated immunity. Immunol. Today. 15:406-411.
5. Poudrier, J., and T. Owens. 1994. CD54/mtercellular adhesion molecule 1 and major histocompatibility complex II signaling induces B cells to express mterleukin 2 receptors and complements help provided through CD40 ligation. J. Exp. Med. 179:1417-1427.
6. Lane, P.J.L., F.M. McConnell, E.A. Clark, and E. Mellins. 1991. Rapid signaling to B cells by antigen-specific T cells requires CD18/CD54 interaction. J. Immunol. 147:4103-4108.
7. de Fougerolles, A.R., and T.A. Springer. 1992. Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med. 175:185-190.
8. Staunton, D.E., M.L. Dustin, and T.A. Springer. 1989. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-I homologous to ICAM-L Nature (Lond.). 339:61-64.
9. Dustin, M.L., and T.A. Springer. 1991. Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annu. Rev. Immunol. 9:27-66.
10. Deleted in proof.
11. Dang, L.H., and K.L. Rock. 1991. Stimulation of B lymphocytes through surface Ig receptors induces LFA-1 and ICAM-1 dependent adhesion. J. Immunol. 146:3273-3279.
12. Branden, H., and E. Lundgren. 1993. Differential regulation of LFA-1 and ICAM-1 on human primary B-lymphocytes. Cell Immunol. 147:64-72.
13. Voraberger, G., R. Schafer, and C. Stratowa. 1991. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester. J. Immunol. 147:2777-2786.
14. Wertheimer, S.J., C.L. Myers, R.W. Wallace, and T.P. Parks. 1992. Intercellular adhesion molecule-1 gene expression in human endothelial cells: differential regulation by tumor necrosis factor-a and phorbol myristate acetate. J. Biol. Chem. 267:12030-12035.
15. Milbrandt, J. 1987. A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science (Wash. DC). 238:797-799.
16. Lemaire, P., O. Revelant, R. Bravo, and P. Charnay. 1988. Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells. Proc. Natl. Acad. Sci. USA. 85:4691-4695.
17. Christy, B.A., L.F. Lau, and D. Nathans. 1988. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. Proc. Natl. Acad Sci. USA. 85:7857-7861.
18. Lim, R.W., B.C. Barnum, and H.R. Herschman. 1987. Cloning of tetra-decanoyl phorbol ester-induced "primary response" sequences and their expression in density-arrested Swiss 3T3 cells and a TPA nonproliferative variant. Oncogene. 1:263-270.
19. Seyfert, V.L., S. McMahon, W. Glenn, X. Cao, V.P. Sukhatme, and J.G. Monroe. 1990. Egr-1 expression in surface Ig-mediated B cell activation: kinetics and association with protein kinase C activation. J. Immunol. 145:3647-3653.
20. Carman, J.A., and J.G. Monroe. 1995. The EGR1 protein contains a discrete transcriptional regulatory domain whose deletion results in a truncated protein that blocks EGR1-induced transcription. DNA Cell Biol. 14:581-589.
21. Gashler, A.L., S. Swaminathan, and V.P. Sukhatme. 1993. A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate early transcription factor Egr-1. Mol. Cell. Biol. 13:4556-4571.
22. Russo, M.W., C. Matheny, and J. Milbraridt. 1993. Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor. Mol. Cell. Biol. 13:6858-6865.
23. Kramer, B., A. Meichle, G. Hensel, P. Camay, and M. Kronke. 1994. Characterization of an Krox-24/Egr-1-responsive element in the human tumor necrosis factor promoter. Biochim. Biophys. Acta. 1219:413-421.
24. Molnar, G., A. Crozat, and A.B. Pardee. 1994. The immediate-early gene EGR-1 regulates the activity of the thymidme kinase promoter at the G0-to-G1 transition of the cell cycle. Mol. Cell. Biol. 14:5242-5248.
25. Thiel, G., S. Schoch, and D. Petersohn. 1994. Regulation of synapsm I gene expression by the zinc finger transcription factor zif268/egr-1. J. Biol. Chem. 269:15294-15301.
26. Ackerman, S.L., A.G. Minden, G.T. Williams, C. Bobnis, and C.-Y. Yeung. 1991. Functional significance of an over-lapping consensus binding motif for Sp1 and Zif268 in the muririe adenosine deaminase gene promoter. Proc. Natl. Acad. Sci. USA. 88:7523-7527.
27. Williams, G.T., and L.F. Lau. 1993. Activation of the inducible orphan receptor gene nur77 by serum growth factors: dissociation of immediate-early and delayed-early responses. Mol. Cell. Biol. 13:6124-6136.
28. Mutero, A., S. Camp, and P. Taylor. 1995. Promoter elements of the mouse acetylcholinesterase gene: transcriptional regulation during muscle differentiation. J. Biol. Chem. 270: 1866-1872.
29. McMahon, S.B., A. Norvell, K.J. Levine, and J.G. Monroe. 1995. Transient transfection of murine B lymphocyte blasts as a method for examining gene regulation in primary B cells. J. Immunol. Methods. 179:251-259.
30. Wechsler, R.J., and J.G. Monroe. 1995. sir-family tyrosine kinase p55jgr is expressed in murine splenic B cells and is activated in response to antigen receptor cross-linking. J. Immunol. 154:3234-3244.
31. Ballantyne, C.M., J. Sligh, Jr., X.Y. Dai, and A.L. Beaudet. 1992. Characterization of the murine Icam-1 gene. Genomics. 14:1076-1080.
32. McMahon, S.B., and J.G. Monroe. 1995. A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor cross-linking in B lymphocytes. Mol. Cell. Biol. 15: 1086-1093.
33. Horton, R.M., Z. Cai, S.N. Ho, and L.R. Pease. 1990. Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. Biotechniques. 8:528-535.
34. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
35. Seyfert, V.L., V.P. Sukhatme, and J.G. Monroe. 1989. Differential expression of a zinc finger-encoding gene in response to positive versus negative signaling through receptor immunoglobulin in murine B lymphocytes. Mol. Cell. Biol. 9: 2083-2088.
36. Xie, H., T.C. Chiles, and T.L. Rothstein. 1993. Induction of CREB activity via the surface Ig receptor of B cells. J. Immunol. 151:880-889.
37. Chiles, T.C., J. Liu, and T.L. Rothstein. 1991. Cross-linking of surface Ig receptors on murine B lymphocytes stimulates the expression of nuclear tetradecanoyl phorbol acetateresponse element-binding proteins. J. Immunol. 146:1730-1735.
38. Henthorn, P., P. Zervos, M. Raducha, H. Harris, and T. Kadesch. 1988. Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression. Proc. Natl. Acad. Sci. USA. 85:6342-6346.
39. Seyfert, V.L., S.B. McMahon, W.D. Glenn, A.J. Yellen, V.P. Sukhatme, X. Cao, and J.G. Monroe. 1990. Methylation of an immediate-early mducible gene as a mechanism for B cell tolerance induction. Science (Wash. DC). 250:797-800.
40. Sukhatme, V.P., X. Cao, L.C. Chang, C.-H. Tsai-Morris, D. Stamcnkovich, P.C.P. Ferreira, D.R. Cohen, S.A. Edwards, T.B. Shows, T. Curran, et al. 1988. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell. 53:37-43.
41. Patwardhan, S., A. Gashler, M.G. Siegel, L. C. Chang, L.J. Joseph, T.B. Shows, M.M. Le Beau, and V.P. Sukhatme. 1991. EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors. Oncogene. 6: 917-928.
42. Joseph, L.J., M.M. Le Beau, G.A.J. Jamieson, S. Acharya, T.B. Shows, J.D. Rowley, and V.P. Sukhatme. 1988. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure. Proc. Natl. Acad. Sci. USA. 85: 7164-7168.
43. Crosby, S.D., R.A. Veile, H. Donis-Keller, J.M. Baraban, R.V. Bhat, K.S. Simburger, and J. Milbrandt. 1992. Neural-specific expression, genomic structure, and chromosomal localization of the gene encoding the zinc-finger transcription factor NGFI-C. Proc. Natl. Acad. Sci. USA. 89:4739-4743.
44. Saffer, J.D., S.P. Jackson, and M.B. Annarella. 1991. Developmental expression of SpI in the mouse. Mol. Cell. Biol. 11: 2189-2199.
45. Sligh, J., Jr., C.M. Ballantyne, S.S. Rich, H.K. Hawkins, C.W. Smith, A. Bradley, and A.L. Beaudet. 1993. Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA. 90:8529-8533.
46. Xu, H., J.A. Gonzalo, Y. St Pierre, I.R. Williams, T.S. Kupper, R.S. Cotran, T.A. Springer, and J.C. Gutierrez-Ramos. 1994. Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. J. Exp. Med. 180: 95-109.
47. McMahon, S.B., and J.G. Monroe. 1995. Activation of the p21ras pathway couples antigen receptor stimulation to induction of the primary response gene egr-1 in B lymphocytes. J. Exp. Med. 181:417-422.
48. Cornelius, L.A., J.T. Taylor, K. Degitz, L.J. Li, T.J. Lawley, and S.W. Caughman. 1993. A 5′ portion of the ICAM-1 gene confers tissue-specific differential expression levels and cytokine responsiveness. J. Invest. Dermatol. 100:753-758.
49. Ledebur, H.C., and T.P. Parks. 1995. Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells: essential roles of a variant NF-kB site and p65 homodimers. J. Biol. Chem. 270:933-943.
50. Maltzman, J., J.A. Carman, and J.G. Monroe. 1996. A role for EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes. Mol. Cell. Biol. In press.
51. Scheinman, R.I., A. Gualberto, C.M. Jewell, J.A. Cidlowski, and A.S.J. Baldwin. 1995. Characterization of mechanisms involved in transrepression by activated glucocorticoid receptors. Mol. Cell Biol. 15:943-953.
52. Stein, B., and A.S.J. Baldwin. 1993. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kB. Mol. Cell. Biol. 13:7191-7198.
53. John, S., R B. Reeves, J.X. Lin, R. Child, J.M. Leiden, C.B. Thompson, and W.J. Leonard. 1995. Regulation of cell-type-specihc interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins. Mol. Cell. Biol. 15:1786-1796.
54. Gonzalez, G.A., and M.R. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell. 59:675-680.
55. Lee, C.Q., Y. Yun, J.P. Hoeffler, and J.F. Habener. 1990. Cyclic-AMP-responsivc transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO (Eur. Mol. Biol. Organ.) J. 9:4455-4465.
56. Hunter, T., and M. Karin. 1992. The regulation of transcription by phosphorylation. Cell. 70:375-387.
57. Lemaire, P., C. Vesque, J. Schmitt, H. Sunnenberg, R. Frank, and P. Chirney. 1990. The serum-inducible mouse gene Krox-24 encodes a sequence-specific transcriptional activator. Mol. Cell. Biol. 10:3456-3467.
58. Hyun, S.W., K. Park, Y.S. Lee, Y.I. Lee, and S.-J. Kim. 1994. Inhibition of protein phosphatases activates P4 promoter of the human insulin-like growth factor II gene through the specific promoter element. J. Biol. Chem. 269: 364-368.
59. Cao, X.M., R.A. Koski, A. Gashler, M. McKiernan, C.F. Moms, R. Gaffney, R.V. Hay, and V.P. Sukhatme. 1990. Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol. Cell. Biol. 10:1931-1939.