Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro

BioFactors

Volumn 14, Issue 1-4, 2001, Pages 169-177

  Unni, Emmanual ^a   Singh, Uma ^a   Ganther, Howard E ^b   Sinha, Raghu ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Apoptosis; Caspase 3 activation; Chemoprevention; Poly(ADP ribose)polymerase; Se methylselenocysteine

Indexed keywords

CASPASE 3; CASPASE 6; CASPASE 8; DNA FRAGMENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SE METHYLSELENOCYSTEINE; SELENOCYSTEINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BREAST TUMOR; CHEMOPROPHYLAXIS; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALIA;

EID: 0034840402     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520140122     Document Type: Conference Paper

References (37)

1. Comparative cytotoxicity of 14 novel selenocysteine se-conjugates in rat renal proximal tubular cells
2. Allium chemistry: Identification of selenoamino acids in ordinary and selenium-enriched garlic, onion, and broccoli using gas chromatography with atomic emission detection
3. Induction of apoptosis by selenite and selenodiglutathione in HL-60 cells: Correlation with cytotoxicity
4. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial
5. Caspases: The executioners of apoptosis
6. The role of caspases in T cell development and the control of immune responses
7. Mechanisms and functions of cell death
8. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: Complexities with thioredoxin reductase
9. Apoptosis: Molecular aspects of cell death and disease
10. Activity of methylated forms of selenium in cancer prevention
11. Relationship between chemical form of selenium and anticarcinogenic activity
12. Chemical form of selenium, critical metabolites and cancer prevention
13. Selenium enriched garlic inhibits the early stage but not the late stage of mammary carcinogenesis
14. Cytostasis and cancer chemoprevention: Investigating the action of triphenylselenonium chloride in in vivo models of mammary carcinogenesis
15. In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention
16. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
17. 1,3-Selenazine derivatives induce cytotoxicity and DNA fragmentation in human HT-1080 fibrosarcoma cells
18. The selenium metabolite selenodiglutathione induces p53 and apoptosis: Relevance to the chemopreventive effects of selenium
19. Selenite induction of DNA strand breaks and apoptosis in mouse leukemic L1210 cells
20. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
21. Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis
22. Involvement of polyamines in selenomethionine induced apoptosis and mitotic alterations in human tumor cells
23. Effects of organic and inorganic selenium compounds on rat mammary tumor cells
24. Caspases: Intracellular signaling by proteolysis
25. Sodium selenite-induced oxidative stress and apoptosis in human hepatoma HepG2 cells
26. Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells
27. Induction of differentiation and apoptosis by sodium selenite in human colonic carcinoma cells (HT29)
28. Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis
29. Selenium causes growth inhibition and apoptosis in human brain tumor cell lines
30. Yama/CPP32 beta, a mammalian homologue of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
31. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
32. Effect of selenium in combination with adriamycin or taxol on several different cancer cells
33. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
34. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer
35. Involvement of cellular proteolytic machinery in apoptosis
36. Apoptosis induced by selenium in human glioma cell lines