Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic chick sympathetic neurones

Journal of Physiology

Volumn 509, Issue 3, 1998, Pages 651-665

  Yu, C Ron ^a   Role, Lorna W ^a  

^a Columbia University Irving Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; ANTISENSE OLIGONUCLEOTIDE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; ACETYLCHOLINE; BUNGAROTOXIN RECEPTOR; CHLORIDE; METHYLLYCACONITINE; ACONITINE; ALPHA-BUNGAROTOXIN RECEPTOR; BUNGAROTOXIN; CALCIUM; DRUG DERIVATIVE; INSECTICIDE;

ANIMAL CELL; ARTICLE; CHICK EMBRYO; EMBRYO; NONHUMAN; PRIORITY JOURNAL; SYMPATHETIC NERVE CELL; ANIMAL EMBRYO; CHICK; CHLORIDE CURRENT; CONTROLLED STUDY; EVOKED RESPONSE; HIPPOCAMPUS; MEMBRANE CONDUCTANCE; PARASYMPATHETIC NERVE CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; CHANNEL GATING; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ELECTRIC CONDUCTIVITY; GENE DELETION; GENETICS; KINETICS; MUTAGENESIS; NERVE CELL; NUCLEIC ACID PROBE; PATCH CLAMP; PHYSIOLOGY; SYMPATHETIC GANGLION;

ACETYLCHOLINE; ACONITINE; ANIMALS; ANTISENSE ELEMENTS (GENETICS); BUNGAROTOXINS; CALCIUM; CHICK EMBRYO; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; GANGLIA, SYMPATHETIC; GENE DELETION; INSECTICIDES; ION CHANNEL GATING; KINETICS; MUTAGENESIS; NEURONS; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC;

EID: 0032525992     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.651bm.x     Document Type: Article

References (40)

1. ALKONDON, M. & ALBUQUERQUE, E. X. (1993). Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes. Journal of Pharmacology and Experimental Therapeutics 265, 1455-1473.
2. ALKONDON, M. & ALBUQUERQUE E. X. (1994). Presence of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat olfactory bulb neurons. Neuroscience Letters 176, 152-156.
3. ALKONDON, M., PEREIRA, E. F., WONNACOTT, S. & ALBUQUERQUE, E. X. (1992). Blockade of nicotinic currents in hippocampal neurons define methyllycaconitine as a potent and specific receptor antagonist. Molecular Pharmacology 41, 802-808.
4. ALKONDON, M., PEREIRA, E. F. R., BARBOSA, C. T. F. & ALBUQUERQUE, E. X. (1997a). Neuronal nicotinic acetylcholine receptor activation modulates GABA release from CA1 neurons of rat hippocampal slices. Journal of Pharmacology and Experimental Therapeutics 283, 1396-1411.
5. ALKONDON, M., PEREIRA, E. F. R., CORTES, W. S., MAELICKE, A. & ALBUQUERQUE, E. X. (1997b). Choline is a selective agonist of alpha 7 nicotinic acetylcholine receptors in the rat brain neurons. European Journal of Neuroscience 9, 2734-2742.
6. ANAND, R., PENG, X., BALLESTA, J. J. & LINDSTROM, J. (1993a). Pharmacological characterization of alpha-bungarotoxin-sensitive acetylcholine receptors immunoisolated from chick retina: contrasting properties of alpha 7 and alpha 8 subunit-containing subtypes. Molecular Pharmacology 44, 1046-1050.
7. ANAND, R., PENG, X. & LINDSTROM, J. (1993b). Homomeric and native alpha 7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex. FEBS Letters 327, 241-246.
8. BERTRAND, D., BERTRAND, S. & BALLIVET, M. (1992). Pharmacological properties of the homomeric alpha 7 receptor. Neuroscience Letters 146, 87-90.
9. BRITTO, L. R., HAMASSAKI-BRITTO, D. E., FERRO, E. S., KEYSER, K. T., KARTEN, H. J., & LINDSTROM, J. M. (1992). Neurons of the chick brain and retina expressing both alpha-bungarotoxin-sensitive and alpha-bungarotoxin-insensitive nicotinic acetylcholine receptors: an immunohistochemical analysis. Brain Research 590, 193-200.
10. BRUSSAARD, A. B., YANG, X., DOYLE, J. P., HUCK, S. & ROLE, L. W. (1994). Developmental regulation of multiple nicotinic AChR channel subtypes in embryonic chick habenula neurones: contributions of both the alpha 2 and alpha 4 subunit genes. Pflügers Archiv 429, 27-43.
11. CASTRO, N. G. & ALBUQUERQUE, E. X. (1995). alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophysical Journal 68, 516-524.
12. CLARKE, P. B. (1992). The fall and rise of neuronal alpha-bungarotoxin binding proteins. Trends in Pharmacological Sciences 13, 407-413.
13. CLARKE, P. B. S., SCHWARTZ, R. D., PAUL, S. M. & PERT, A. (1985). Nicotine binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin. Journal of Neuroscience 5, 1307-1315.
14. COUTURIER, S., BERTRAND, D., MATTER, J. M., HERNANDEZ, M. C., BERTRAND, S., MILLAR, N., VALERA, S., BARKAS, T. & BALLIVET, M. (1990). A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron 5, 847-856.
15. 2+/calmodulin-dependent kinase pathway. Journal of Neuroscience 15, 7966-7978.
16. DEVAY, P., Qu, X. & ROLE, L. (1994). Regulation of nAChR subunit gene expression relative to the development of pre- and postsynaptic projections of embryonic chick sympathetic neurons. Developmental Biology 162, 56-70.
17. DRASDO, A., CAULFIELD, M., BERTRAND, D., BERTRAND, S. & WONNACOTT, S. (1992). Methyllycaconitine: a novel nicotinic antagonist. Molecular and Cellular Neurosciences 3, 237-243.
18. GALZI, J. L., DEVILLERS-THIERY, A., HUSSY, N., BERTRAND, S., CHANGEUX, J. P., & BERTRAND, D. (1992). Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature 359, 500-505.
19. HOFFMAN, P. W., RAVINDRAN, A. & HUGANIR, R. L. (1994). Role of phosphorylation in desensitization of acetylcholine receptors expressed in Xenopus oocytes. Journal of Neuroscience 14, 4185-4195.
20. HOPFIELD, J. F., TANK, D. W., GREENGARD, P. & HUGANIR, R. L. (1988). Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation. Nature 336, 677-680.
21. JACOB, M. H. (1991). Acetylcholine receptor expression in developing chick ciliary ganglion neurons. Journal of Neuroscience 11, 1701-1712.
22. KEYSER, K. T., BRITTO, L. R., SCHOEPFER, R., WHITING, P., COOPER, J., CONROY, W., BROZOZOWSKA-PRECHTL, A., KARTEN, H. J., & LINDSTROM, J. (1993). Three subtypes of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors are expressed in chick retina. Journal of Neuroscience 13, 442-454.
23. LINDSTROM, J., ANAND, R., PENG, X., GERZANICH, V., WANG, F. & Li, Y. (1995). Neuronal nicotinic receptor subtypes. Annals of the New York Academy of Sciences 757, 100-116.
24. LISTERUD, M., BRUSSAARD, A. B., DEVAY, P., COLMAN, D. R, & ROLE, L. W. (1991). Functional contribution of neuronal AChR subunits revealed by antisense oligonucleotides Science 254, 1518-1521.
25. MCGEHEE, D. S., HEATH, M. J., GELBER, S., DEVAY, P & ROLE, L. W. (1995). Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269, 1692-1696.
26. MCGEHEE, D. S. & ROLE, L. W. (1995). Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annual Review of Physiology 57, 521-546.
27. MARGIOTTA, J. F. & GURANTZ, D. (1989). Changes in the number, function, and regulation of nicotinic acetylcholine receptors during neuronal development. Developmental Biology 135, 326-339.
28. Moss, B. L. & ROLE, L. W. (1993). Enhanced ACh sensitivity is accompanied by changes in ACh receptor channel properties and segregation of ACh receptor subtypes on sympathetic neurons during in nervation in vivo. Journal of Neuroscience 13, 13-28.
29. Moss, B. L., SCHUETZE, S. M. & ROLE, L. W, (1989). Functional properties and developmental regulation of nicotinic acetylcholine receptors on embryonic chicken sympathetic neurons. Neuron 3, 597-607.
30. PALMA, E., BERTRAND, S., BINZONI, T. & BERTRAND, D. (1996). Neuronal nicotinic α7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. Journal of Physiology 491, 151-162.
31. PUGH, P. C., CORRIVEAU, R. A., CONROY, W. G. & BERG, D. K. (1995). Novel subpopulation of neuronal acetylcholine receptors among those binding alpha-bungarotoxin. Molecular Pharmacology 47, 717-725.
32. SARGENT, P. B. (1993). The diversity of neuronal nicotinic acetylcholine receptors. Annual Review of Neuroscience 16, 403-443.
33. SEGUELA, P., WADICHE, J., DINELEY-MILLER, K., DANI, J. A. & PATRICK, J. W. (1993). Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. Journal of Neuroscience 13, 596-604.
34. SIMMONS, L. K., SCHUETZE, S. M. & ROLE, L. W. (1990). Substance P modulates single-channel properties of neuronal nicotinic acetylcholine receptors. Neuron 4, 393-403.
35. 2+ Neuron 8, 353-362.
36. WAKD, J. M., COCKCROFT, V. B., LUNT, G. G., SMILLIE, F. S. & WONNACOTT, S. (1990) Methyllycaconitine: a selective probe for neuronal alpha-bungarotoxin binding sites. FEBS Letter 270, 45-48.
37. WILKIE, G. I., HUTSON, P., SULLIVAN, J. P. & WONNACOTT, S. (1996). Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes. Neurochemistry Research 21, 1141-1148.
38. YU, C., BRUSSAARD, A. B., YANG, X., LISTERUD, M. & ROLE, L. W. (1993). Uptake of antisense oligonucleotides and functional block of acetylcholine receptor subunit gene expression in primary embryonic neurons. Developmental Genetics 14, 296-304.
39. YU, C. R. & ROLE, L. W. (1998). Functional contribution of the α5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurones. Journal of Physiology 509, 667-681.
40. ZHANG, Z. W., VIJAYARAGHAVAN, S. & BERG, D. K. (1994). Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron 12, 167-177.